We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.
In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
Read More
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
Read More
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
Read More
Most Useful Reviews
9
Promotes hair growth
4 people found this helpful
My mother has type 2 diabetes and since taking biotin, her hair loss has decreased significantly. After starting biotin alongside her ketogenic diet, she noticed new hair growth. She plans to continue purchasing this product as it has been effective for her hair and glucose levels.
Read More
7.5
Stabilises sugar levels
14 people found this helpful
I take biotin for its benefits on hair and nails. It assists with carbohydrate metabolism and is beneficial for hair fragility and skin health. The optimal dosage for hair treatment is about 5,000 mcg per day. I’ve been alternating it with other vitamins, and I've noticed my hair's improved shine and strength. It also seems to help stabilise my blood sugar levels as a diabetic.
Read More
7.5
Supports healthy hair
7 people found this helpful
I ordered biotin for my hair loss and it has helped tremendously. In addition to improving my hair health, I've noticed benefits for my skin and overall energy. Biotin's effects on glucose metabolism are particularly helpful for my condition as a diabetic. It has truly made a difference in my appearance and well-being.
We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.
In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
Read More
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
Read More
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.5
All Reviews
Positive Reviews
Negative Reviews
9
Promotes hair growth
4 people found this helpful
My mother has type 2 diabetes and since taking biotin, her hair loss has decreased significantly. After starting biotin alongside her ketogenic diet, she noticed new hair growth. She plans to continue purchasing this product as it has been effective for her hair and glucose levels.
Read More
7.5
Stabilises sugar levels
14 people found this helpful
I take biotin for its benefits on hair and nails. It assists with carbohydrate metabolism and is beneficial for hair fragility and skin health. The optimal dosage for hair treatment is about 5,000 mcg per day. I’ve been alternating it with other vitamins, and I've noticed my hair's improved shine and strength. It also seems to help stabilise my blood sugar levels as a diabetic.
Read More
7.5
Supports healthy hair
7 people found this helpful
I ordered biotin for my hair loss and it has helped tremendously. In addition to improving my hair health, I've noticed benefits for my skin and overall energy. Biotin's effects on glucose metabolism are particularly helpful for my condition as a diabetic. It has truly made a difference in my appearance and well-being.
Read More
7.5
Helps blood sugar
Biotin is excellent for strengthening hair and nails since it aids in keratin synthesis. It also enhances metabolic function and can lower blood sugar levels for diabetic patients. This vitamin may improve mood and stimulate better health overall. Consistency in taking biotin can lead to beneficial results.
Read More
7.5
Improves nails strength
Biotin plays a crucial role in metabolism, energy production and strengthening nails. Studies have shown it can reduce brittleness in nails. I’ve used a dosage of 10,000 mcg and have experienced good results in nail thickness and health. It may also be effective for managing blood glucose in diabetic individuals.
Diabetes is a chronic medical condition that occurs when the body either does not produce enough insulin or cannot effectively use the insulin it produces. Insulin is a hormone made by the pancreas that helps glucose from food enter the cells, providing them with energy. When diabetes is present, it leads to elevated levels of glucose in the blood, which can cause serious health complications if left unmanaged. There are primarily two types: Type 1 diabetes, which is an autoimmune condition where the body attacks insulin-producing cells, and Type 2 diabetes, which is often associated with lifestyle factors such as obesity and lack of physical activity, leading to insulin resistance.
Managing diabetes typically involves a combination of lifestyle changes, such as a balanced diet and regular exercise, along with monitoring blood sugar levels and, in many cases, medication or insulin therapy. Education is crucial for those with diabetes to understand how their condition works and how to manage it effectively. The goal of diabetes management is to keep blood sugar levels within a target range, helping to prevent complications such as heart disease, nerve damage, and kidney failure. Regular check-ups and consultations with healthcare professionals are essential to ensure optimal care.
Biotin, also known as vitamin B7, is a water-soluble B-vitamin that plays a crucial role in various metabolic processes in the body. It is essential for converting nutrients into energy and is involved in the synthesis of fatty acids, amino acids, and glucose. Biotin is naturally found in a variety of foods, including eggs, nuts, seeds, fish, meat, dairy products, and certain vegetables. While deficiencies are rare due to its abundance in common diets, they can lead to symptoms such as hair loss, skin rashes, and neurological issues.
Many people take biotin supplements believing they can improve hair, skin, and nail health. Although there is some evidence to support the benefits of biotin for hair growth—especially in those with a deficiency—more research is needed to establish its efficacy for those with sufficient levels. The FDA does not regulate dietary supplements as strictly as medications, so it’s crucial to choose high-quality products from reputable manufacturers. Always consult with a healthcare professional before starting any new supplement to ensure it’s appropriate for your specific needs.
Based on user reviews, the time it takes to see results from taking biotin for diabetes can vary. Many users report noticing improvements in hair loss and blood sugar regulation within a few weeks to a couple of months. For instance, one user mentioned that after nearly a month of use, they observed less hair loss and stronger nails alongside improved blood glucose levels Read Review. Another user experienced significant hair growth and nail thickness after three months, while also noting stabilization in blood sugar levels during that time Read Review.
Overall, many users seem to agree that consistency is key, and taking biotin regularly can lead to beneficial metabolic results over time. Some users mention that longer-term use, typically spanning several months, may be required to fully gauge its impact on glucose management, but even shorter durations can yield positive effects Read Review.
This supplement has some scientific research supporting its potential benefits for diabetes, particularly through biotin. A study indicated that biotin supplementation might aid metabolism in individuals with severe obesity and type 2 diabetes by enhancing gut health and potentially reducing blood sugar issues [2]. This suggests that biotin could play a role in preventing metabolic decline for those affected by these conditions.
Moreover, another study investigated high-dose biotin as an aid for managing type 1 diabetes, aiming to improve liver enzyme expression crucial for maintaining blood sugar levels. While early pilot trials showed promising outcomes, definitive benefits have yet to be confirmed, pointing towards the need for further research to better understand biotin's efficacy in diabetes management [3]. In conclusion, while there is some scientific support for biotin as a diabetes supplement, the evidence is not conclusive, warranting additional studies to fully unlock its potential.
Users have reported a range of improvements in symptoms after taking biotin, particularly regarding hair health and blood sugar regulation. For instance, one user noted a significant decrease in hair loss and new hair growth after combining biotin with a ketogenic diet Read Review. Another user mentioned experiencing thicker hair and rapid nail growth after three months of use, alongside stabilization of their blood sugar levels, highlighting biotin's potential benefits for those managing diabetes Read Review.
Additionally, several reviews indicate that biotin supports overall energy and skin health, contributing to a feeling of increased well-being. For those with brittle nails, users often report thickness and strength improvements Read Review. While users agree on the positive effects of biotin, individual results can vary. Consistency in dosage and a healthy lifestyle can significantly enhance its impact, with some users recommending dosages around 5,000 to 10,000 mcg Read Review.
Users report a positive experience when combining biotin with other supplements for managing diabetes. Many noted that biotin's effects on glucose metabolism can be enhanced by taking it alongside a healthy diet, such as a ketogenic approach, leading to improved hair growth and stabilization of blood sugar levels Read Review. Several users also mentioned positive outcomes when taking biotin with other vitamins, such as vitamin C, further suggesting that such combinations may bolster its benefits for both hair health and diabetes management Read Review.
Additionally, users highlight the importance of consistency in taking biotin to derive significant benefits. Combining it with a comprehensive health regimen, including adequate hydration and other nutrients, plays a crucial role in optimizing its effects on glucose regulation Read Review. Some users express optimism that, after a period of consistent use, biotin can contribute to better metabolic control and overall well-being, particularly for diabetics Read Review.
Based on user reviews, the right dose for biotin in treating diabetes appears to vary, but several users suggest a range between 5,000 to 10,000 mcg per day. One user specifically noted that they use a dosage of 5,000 mcg daily, which they found to effectively stabilize blood sugar levels while also improving hair health (Read Review). Another user reported positive results with a 10,000 mcg dosage, highlighting improvements not only in nail strength but also in the management of blood glucose levels for diabetic patients (Read Review).
Overall, users consistently emphasize biotin's benefits in aiding carbohydrate metabolism and potentially lowering blood sugar levels, which makes it a popular supplement among those managing diabetes. For instance, a user mentioned that biotin notably helped with glucose metabolism and overall well-being after usage (Read Review). While personal experiences may vary, these insights suggest that finding the right dose within this range could contribute positively to managing diabetes symptoms alongside other health benefits.
7.5
Reduces hair loss
After nearly a month of use, I've noticed less hair loss, likely due to age, diabetes, and COVID. My nails feel stronger too. I take it alongside vitamin C and believe it will help with hair loss further.
6
Improves stability
3 people found this helpful
After taking biotin for three months, I’ve experienced significant hair growth and thicker strands. Although I didn't see much change in my skin, my nails grew rapidly. As a person with insulin-dependent diabetes, I also noticed a stabilization in my blood sugar levels while using this supplement.
7.5
Helps manage diabetes
I started taking biotin based on an endocrinologist's advice to regulate my blood sugar with diabetes. She cited studies showing it could help lower sugar levels after several months. I'm hopeful about its long-term benefits for managing my dietary conditions while supporting my overall health.
9
Promotes hair growth
4 people found this helpful
My mother has type 2 diabetes and since taking biotin, her hair loss has decreased significantly. After starting biotin alongside her ketogenic diet, she noticed new hair growth. She plans to continue purchasing this product as it has been effective for her hair and glucose levels.
7.5
Improves nails strength
Biotin plays a crucial role in metabolism, energy production and strengthening nails. Studies have shown it can reduce brittleness in nails. I’ve used a dosage of 10,000 mcg and have experienced good results in nail thickness and health. It may also be effective for managing blood glucose in diabetic individuals.
7.5
Stabilises sugar levels
14 people found this helpful
I take biotin for its benefits on hair and nails. It assists with carbohydrate metabolism and is beneficial for hair fragility and skin health. The optimal dosage for hair treatment is about 5,000 mcg per day. I’ve been alternating it with other vitamins, and I've noticed my hair's improved shine and strength. It also seems to help stabilise my blood sugar levels as a diabetic.
7.5
Reduces sugar levels
Biotin is essential for metabolism and energy production, and it plays a critical role in regulating blood sugar levels. A deficiency can lead to various symptoms, including hair loss and skin issues. It’s particularly impactful for those managing diabetes, making it a useful supplement for overall health.
6
Improves blood sugar
84 people found this helpful
Biotin significantly helped my severe hair loss. It is vital for hair, skin, and nails, and is essential for glucose metabolism and the nervous system. After taking it, I've noticed improvements in my hair and skin condition, enhancing my overall well-being. It’s important for managing diabetes and aids protein absorption, promoting energy conversion.
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
References
Cai X, Zhang M, Zou J, Wang L, Zhan Y, et al. A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1 functionality enhances islet survival to improve islet transplantation outcome in diabetes treatment. J Nanobiotechnology. 2024;22:792. doi:10.1186/s12951-024-03072-5
Belda E, Voland L, Tremaroli V, Falony G, Adriouch S, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut. 2022;71:2463. doi:10.1136/gutjnl-2021-325753
McCarty MF. In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control. Med Hypotheses. 2016;95:45. doi:10.1016/j.mehy.2016.08.002