Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 12 Reviews
8
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Vitamin B-6 (as Pyridoxine Hydrochloride)
10 mg
588%
Calcium (as Calcium Carbonate)
60 mg
5%
Melatonin
5 mg
*

Top Medical Research Studies

9
Melatonin aids perimenopausal relief
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.

After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.

Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
Read More
9
Melatonin boosts bone health
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.

In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.

The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
Read More
We examined the impact of melatonin on chronic dyspepsia in postmenopausal women, particularly those infected with Helicobacter pylori. The study involved 152 participants across various groups, including healthy women and those with H. pylori infection.

After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.

Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
Read More

Most Useful Reviews

7.5
Effective sleep aid
10 people found this helpful
I was taking benzodiazepines for insomnia during menopause, but they didn’t work and left me dazed in the morning. After hearing positive feedback, I tried this and was astonished by its effectiveness. I felt drowsy within 20 minutes and slept through the night. I found it a bit strong, so I plan to cut the dosage next time. The size is small and tasteless, making it easy to take. I believe it offers great value for money.
Read More
9
Dramatic improvement
2 people found this helpful
This has saved me from the struggles of menopause! I often find it hard to sleep, but after taking this melatonin an hour before bed, I experience genuine drowsiness and fall asleep easily, without waking up at night. I’ve been using it every two days and have begun to sleep soundly even without it. It feels like a natural solution restoring my sleep.
Read More
9
Relief from insomnia
1 people found this helpful
This product is essential for me! It helps me sleep soundly at night, eliminating the disruptions caused by menopause. I take it every night and have found it incredibly reliable. I am grateful for its impact on my sleep quality.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
  • All Researches
9
Melatonin aids perimenopausal relief
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.

After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.

Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
Read More
9
Melatonin reduces menopause symptoms effectively
We explored how a blend of soy isoflavones, 8-prenylnaringenin, and melatonin affects hot flashes in postmenopausal women. Over 12 weeks, 44 participants reported significant reductions in hot flash frequency and improvements in health-related quality of life.

By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
Read More
9
Melatonin boosts bone health
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.

In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.

The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
Read More
We examined the impact of melatonin on chronic dyspepsia in postmenopausal women, particularly those infected with Helicobacter pylori. The study involved 152 participants across various groups, including healthy women and those with H. pylori infection.

After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.

Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
Read More
8
Melatonin shows promise for menopause
We explored the role of melatonin in reducing depression and anxiety among postmenopausal women by reviewing multiple randomized controlled trials. Our analysis included five studies with 441 participants, revealing that melatonin significantly lessened symptoms of both depression and anxiety.

This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective sleep aid
10 people found this helpful
I was taking benzodiazepines for insomnia during menopause, but they didn’t work and left me dazed in the morning. After hearing positive feedback, I tried this and was astonished by its effectiveness. I felt drowsy within 20 minutes and slept through the night. I found it a bit strong, so I plan to cut the dosage next time. The size is small and tasteless, making it easy to take. I believe it offers great value for money.
Read More
9
Dramatic improvement
2 people found this helpful
This has saved me from the struggles of menopause! I often find it hard to sleep, but after taking this melatonin an hour before bed, I experience genuine drowsiness and fall asleep easily, without waking up at night. I’ve been using it every two days and have begun to sleep soundly even without it. It feels like a natural solution restoring my sleep.
Read More
9
Relief from insomnia
1 people found this helpful
This product is essential for me! It helps me sleep soundly at night, eliminating the disruptions caused by menopause. I take it every night and have found it incredibly reliable. I am grateful for its impact on my sleep quality.
Read More
7.5
Just right dosage
1 people found this helpful
I was feeling that 3mg of melatonin wasn’t effective during menopause, so I switched to 5mg. This dosage feels just right; I fall asleep easily and wake up refreshed, without the drowsiness commonly associated with sleep aids. Now, it is an essential part of my routine for better sleep.
Read More
8
Effective for light sleep
I noticed sleep disturbances during menopause, such as light sleep and waking up at night. However, after taking this melatonin, I felt drowsy soon afterward and was able to fall asleep quickly, which was a relief.
Read More

Frequently Asked Questions

7.5
Effective sleep aid
10 people found this helpful
I was taking benzodiazepines for insomnia during menopause, but they didn’t work and left me dazed in the morning. After hearing positive feedback, I tried this and was astonished by its effectiveness. I felt drowsy within 20 minutes and slept through the night. I found it a bit strong, so I plan to cut the dosage next time. The size is small and tasteless, making it easy to take. I believe it offers great value for money.
9
Dramatic improvement
2 people found this helpful
This has saved me from the struggles of menopause! I often find it hard to sleep, but after taking this melatonin an hour before bed, I experience genuine drowsiness and fall asleep easily, without waking up at night. I’ve been using it every two days and have begun to sleep soundly even without it. It feels like a natural solution restoring my sleep.
7.5
Just right dosage
1 people found this helpful
I was feeling that 3mg of melatonin wasn’t effective during menopause, so I switched to 5mg. This dosage feels just right; I fall asleep easily and wake up refreshed, without the drowsiness commonly associated with sleep aids. Now, it is an essential part of my routine for better sleep.
9
Relief from insomnia
1 people found this helpful
This product is essential for me! It helps me sleep soundly at night, eliminating the disruptions caused by menopause. I take it every night and have found it incredibly reliable. I am grateful for its impact on my sleep quality.
6
Moderate effectiveness
1 people found this helpful
I often wake up multiple times at night due to sleep disorders from menopause. While this supplement helps me to some extent, I still occasionally wake up. I haven’t experienced any adverse reactions while using it, which is a plus.
7.5
Safe alternative
I purchased this for my mother, who struggles with sleep due to menopause. It appears to help her fall asleep more easily, even though she occasionally wakes up at night. I believe it is a safer alternative to regular sleeping pills, and I might try a higher dosage next time.
7.5
Natural sleep aid
1 people found this helpful
I’ve struggled with insomnia due to PMS, but since taking 5mg of melatonin, I find I can fall asleep easily and stay asleep. Previously, 3mg was insufficient. The melatonin suits me well, as it promotes natural sleep without the side effects often found in medications. I've recommended this to friends for its effectiveness.
6
Improved sleep
I bought this as I struggled with sleep due to menopause. I started with half a tablet, and I sleep better than without it. Afterward, I tried one tablet; I did wake up twice, but I wonder if I can sleep when I decide to sleep...
4
Melatonin shows limited menopausal benefits
We examined how melatonin affects menopausal symptoms through a systematic review of eight trials involving over 800 women. While melatonin showed some promise in easing physical symptoms, it didn’t significantly help with sleep quality or broader menopausal issues like mood changes, anxiety, or sexual health. Notably, there were no improvements in weight or hormone levels either. Despite these findings, more extensive research is needed to better understand melatonin's role in menopause management.
9
Melatonin aids perimenopausal relief
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.

After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.

Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
9
Melatonin reduces menopause symptoms effectively
We explored how a blend of soy isoflavones, 8-prenylnaringenin, and melatonin affects hot flashes in postmenopausal women. Over 12 weeks, 44 participants reported significant reductions in hot flash frequency and improvements in health-related quality of life.

By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
9
Melatonin boosts bone health
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.

In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.

The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
8
Melatonin shows promise for menopause
We explored the role of melatonin in reducing depression and anxiety among postmenopausal women by reviewing multiple randomized controlled trials. Our analysis included five studies with 441 participants, revealing that melatonin significantly lessened symptoms of both depression and anxiety.

This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.

References

  1. Demirhan Kayacik A, İlcioglu K. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials. Arch Womens Ment Health. 2024;27:265. doi:10.1007/s00737-023-01395-0
  2. Zhang J, Jiang B. Influence of Melatonin Treatment on Emotion, Sleep, and Life Quality in Perimenopausal Women: A Clinical Study. J Healthc Eng. 2023;2023:2198804. doi:10.1155/2023/2198804
  3. Estrugo CP, Rodríguez MT, de Guevara NM, Gómez JG, Ridocci F, et al. Combination of Soy Isoflavones, 8-Prenylnaringenin and Melatonin Improves Hot Flashes and Health-Related Quality of Life Outcomes in Postmenopausal Women: Flavie Study. J Menopausal Med. 2023;29:73. doi:10.6118/jmm.22034
  4. Guan H, Kong N, Tian R, Cao R, Liu G, et al. Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis. J Transl Med. 2022;20:132. doi:10.1186/s12967-022-03341-7
  5. Treister-Goltzman Y, Peleg R. Melatonin and the health of menopausal women: A systematic review. J Pineal Res. 2021;71:e12743. doi:10.1111/jpi.12743
  6. Yi M, Wang S, Wu T, Zhang X, Jiang L, et al. Effects of exogenous melatonin on sleep quality and menopausal symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials. Menopause. 2021;28:717. doi:10.1097/GME.0000000000001757
  7. Chojnacki C, Mędrek-Socha M, Konrad P, Chojnacki J, Błońska A. The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia. BMC Womens Health. 2020;20:262. doi:10.1186/s12905-020-01117-z
  8. Proserpio P, Marra S, Campana C, Agostoni EC, Palagini L, et al. Insomnia and menopause: a narrative review on mechanisms and treatments. Climacteric. 2020;23:539. doi:10.1080/13697137.2020.1799973
  9. Dodda BR, Bondi CD, Hasan M, Clafshenkel WP, Gallagher KM, et al. Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer. Front Oncol. 2019;9:525. doi:10.3389/fonc.2019.00525
  10. Zavodnov OP, Botasheva TL, Vasil'eva VV, Paliyeva NV, Zheleznyakova EV, et al. [Somnological status of women in late reproductive and perimenopausal periods during treatment of sleep disorders using partial light deprivation]. Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119:105. doi:10.17116/jnevro2019119042105
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