Natrol Melatonin Fast Dissolve Tablets

My neurologist suggested 3 mg a night to alleviate my chronic cough as a symptom of trigeminal autonomic cephalalgia. I find it works much better than the pharmacological treatments I tried, which not only failed to help but also caused debilitating side effects.

High Cholesterol details

Better sleep experience

Natrol Melatonin has significantly improved my sleep. Previously, I struggled with insomnia and often found it difficult to sleep, but since using this product, I've been falling asleep quicker and waking up refreshed. The 3mg dosage suits me perfectly, and I haven't encountered any side effects. If you have challenges sleeping or adjusting your sleep schedule, I highly recommend trying this product!

Cancer details

Safe for cancer patients

Excellent sleep aid! I have utilised melatonin as a sleep aid for years, and this product is the most effective I've found. I personally struggle to fall asleep but have no trouble staying asleep, so this product works better for me than time-release melatonin. A naturopathic doctor informed me that melatonin is safe for long-term use and even prescribes it to her cancer patients for its antioxidant benefits; however, she cautioned me never to take it during the day as it can act as a pro-oxidant when exposed to sunlight.

Heart Attack details

When I had worries that kept me awake for an hour, I tried this product. About 20 minutes after taking it, I experienced an intense sleep attack. The effect is remarkable. Even on days I missed a dose, I fell asleep better, possibly thanks to the vitamin B included.

Rash details

Improved sleep quality

The product truly works. I bought it knowing its benefits, not really focusing on any downsides, as I haven’t encountered any. With this product, I enjoy a deep sleep and notice my rash is improved by morning. I wake up early, around 5 am, and aim to stay awake until 10 pm. I engage in morning workouts from 7 am before heading to work. Melatonin enables me to get sufficient rest and wake up refreshed. Just ensure that after taking a pill before bed, you switch off all lights and the TV. The hormone functions best in complete darkness. I highly recommend trying it; you won’t regret it.

Chronic Fatigue Syndrome details

Melatonin ineffective for CFS symptoms

Questionable

Based on 7 Researches

USERS' SCORE

Good

Based on 9 Reviews

Therapy of circadian rhythm disorders in chronic fatigue syndrome: no symptomatic improvement with melatonin or phototherapy.

Most Relevant Research

We evaluated whether melatonin and bright-light phototherapy could help alleviate symptoms of chronic fatigue syndrome (CFS). In a controlled study with thirty participants, we assessed the effectiveness of these treatments by measuring various symptoms over several weeks.

Unfortunately, we found that neither melatonin nor phototherapy led to significant improvements in the patients’ symptoms or overall health. Our findings suggest that these treatments shouldn't be promoted for CFS unless proven beneficial.

9.5

Combatting fatigue effectively

Most Useful Review

An effective product for insomnia, it works quickly and has a lasting impact. It doesn't lead to headaches upon waking, and I can stop using it easily without becoming dependent.

Nausea details

Melatonin linked to nausea management

Based on 2 Researches

Melatonin Immunoreactivity in Malignant Small Intestinal Neuroendocrine Tumours.

Most Relevant Research

We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.

Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.

However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.

9.5

No nausea reported

Most Useful Review

The quality of this company is excellent, and the quantity in the box is appropriate. I recommend trying it for its effectiveness while ensuring you read the description. Importantly, it does not cause nausea.

Insomnia details

Melatonin delivery enhances sleep

Based on 23 Researches

Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.

Most Relevant Research

We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.

Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.

Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.

We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.

9.5

Improved sleep quality

Most Useful Review

Working well. This supplement truly aids my sleep. After struggling with insomnia, I now wake up feeling refreshed and cheerful. Before taking melatonin, I had difficulty sleeping and waking up. I no longer need an alarm clock. I recommend GABA for anyone facing similar insomnia issues.

Dizziness details

Melatonin's impact on dizziness

Addressing Sleep Disorders in Psychiatry: Comparing the Use of Melatonin, Trazodone, and Doxepin.

Most Relevant Research

We assessed how melatonin affects dizziness in patients dealing with sleep disturbances tied to psychiatric conditions. In a study with 175 participants, we found that melatonin was slightly less effective than trazodone and doxepin in improving overall sleep quality. However, it stood out for having a low incidence of adverse effects. Specifically, the rates of dizziness associated with melatonin use were measured, showing a relatively low occurrence.

While it did not provide the most substantial improvement in sleep quality, melatonin showed promise in enhancing tolerability among users. Only 10% of participants reported dizziness, which indicates that melatonin might be a safer option for those worried about side effects from more potent medications. By choosing melatonin, patients can potentially find a balance between managing sleep disturbances while minimizing unwanted symptoms like dizziness.

Overall, we observed that for individuals focused on avoiding adverse effects, melatonin serves as a viable alternative within this treatment landscape. Its effectiveness in curbing dizziness contributes to discussions on how best to treat sleep disorders in psychiatric patients without compromising their comfort.

8.3

Improved sleep quality

Most Useful Review

This has proven effective. Since taking magnesium and Sleep Deep, my sleep quality has significantly improved. I can now attain deep sleep and feel much better during the day, with no dizziness or discomfort, which is a relief.

Autoimmune Disorder details

Melatonin improves MS-related symptoms

Based on 16 Researches

12-week melatonin intake attenuates cardiac autonomic dysfunction and oxidative stress in multiple sclerosis patients: a randomized controlled trial.

Most Relevant Research

We explored the impact of melatonin on patients with multiple sclerosis (MS), aiming to improve heart function and sleep. In a randomized controlled trial, participants received either melatonin or a placebo for 12 weeks.

We observed significant improvements in heart rate variability and markers of oxidative stress, suggesting that melatonin could enhance heart health and lower stress in MS patients. Additionally, sleep quality and quantity also improved with melatonin use.

This study indicates that melatonin might be a beneficial treatment option for managing cardiac issues and sleep disturbances in MS.

9.5

Effective treatment

Most Useful Review

Really helps to establish a sleep routine and is non-addictive! I had a terrible schedule for years, only sleeping in the morning and working late at night. My body was exhausted, leading to hair loss and nodular alopecia, worsened by breastfeeding. After taking melatonin, I fell asleep quickly and adjusted my routine. My bald patches healed, and my hair stopped falling out. Occasionally, I stray from routine, but melatonin helps me return to normal.

Headache details

Agomelatine relieves hypnic headaches

Based on 15 Researches

Case report: Hypnic headache responds to agomelatine-a potential prophylactic treatment option.

Most Relevant Research

We explored how melatonin-based treatments, particularly agomelatine, can affect headaches, focusing on hypnic headaches (HH). This form of headache typically occurs during sleep, disrupting the rest of those affected. A fascinating case of a 58-year-old woman who experienced these nocturnal headaches for three years demonstrated the potential benefits of agomelatine.

After being prescribed 25 mg of agomelatine at bedtime, she reported an impressive 80% reduction in headache frequency and severity within a month. Remarkably, her headaches completely resolved after three months, allowing her to discontinue the medication.

This case highlights the importance of exploring prophylactic treatments aimed at reducing nighttime awakenings caused by HH. Given the significant impact these headaches can have on sleep quality in older populations, treatments that target melatonin receptors could offer a promising avenue for relieving this condition.

8.3

Good for headaches

Most Useful Review

My neurologist advised taking 3 mg nightly to alleviate symptoms of trigeminal autonomic cephalalgia. This is more effective and less taxing than other medications, which caused debilitating side effects.

Sleep Apnea details