Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B-6 (as Pyridoxine Hydrochloride)
10 mg
590%
Calcium (from Calcium Carbonate)
63 mg
4%
Melatonin
3 mg
*
Top Medical Research Studies
9
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
Read More
9
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
Read More
9
We examined the impact of melatonin on chronic dyspepsia in postmenopausal women, particularly those infected with Helicobacter pylori. The study involved 152 participants across various groups, including healthy women and those with H. pylori infection.
After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.
Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.
Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
Read More
Most Useful Reviews
9
Sleep improvement
4 people found this helpful
After ten years of insomnia resulting from menopause, I found melatonin to be the most effective solution compared to GABA and tryptophan. For the first time in ages, I experienced actual sleepiness and could return to sleep if I woke during the night. Initially taking vitamin D prior to melatonin may have helped.
Read More
7.5
Effective for sleep
1 people found this helpful
I switched from 5mg to 3mg as I was struggling to sleep because of menopause. Fortunately, 3mg worked well too, allowing me to drift off comfortably within 30 minutes. Previously, 5mg sometimes caused morning headaches depending on my health, but I haven't experienced any with 3mg. This dosage feels just right for me; I highly recommend it, especially when insomnia makes you feel dreadful.
Read More
9
Insomnia relief
I wouldn't want to be without melatonin. I've been taking it for years due to awful insomnia caused by menopause, and it really works. Moreover, it has improved the quality of my hair, which had started to thin and fall out. I appreciate iHerb's fast and straightforward service.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
- All Researches
9
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
Read More
9
Melatonin reduces menopause symptoms effectively
We explored how a blend of soy isoflavones, 8-prenylnaringenin, and melatonin affects hot flashes in postmenopausal women. Over 12 weeks, 44 participants reported significant reductions in hot flash frequency and improvements in health-related quality of life.
By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
Read More
9
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
Read More
9
We examined the impact of melatonin on chronic dyspepsia in postmenopausal women, particularly those infected with Helicobacter pylori. The study involved 152 participants across various groups, including healthy women and those with H. pylori infection.
After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.
Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
After treating with melatonin, we saw that 84.3% of those receiving the supplement reported symptom relief, compared to only 43.7% in the placebo group. This suggests that melatonin can be an effective treatment for this common issue in postmenopausal women.
Overall, our findings indicate that melatonin supplementation may indeed offer significant benefits in managing dyspeptic symptoms related to H. pylori infection.
Read More
8
We explored the role of melatonin in reducing depression and anxiety among postmenopausal women by reviewing multiple randomized controlled trials. Our analysis included five studies with 441 participants, revealing that melatonin significantly lessened symptoms of both depression and anxiety.
This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Sleep improvement
4 people found this helpful
After ten years of insomnia resulting from menopause, I found melatonin to be the most effective solution compared to GABA and tryptophan. For the first time in ages, I experienced actual sleepiness and could return to sleep if I woke during the night. Initially taking vitamin D prior to melatonin may have helped.
Read More
7.5
Effective for sleep
1 people found this helpful
I switched from 5mg to 3mg as I was struggling to sleep because of menopause. Fortunately, 3mg worked well too, allowing me to drift off comfortably within 30 minutes. Previously, 5mg sometimes caused morning headaches depending on my health, but I haven't experienced any with 3mg. This dosage feels just right for me; I highly recommend it, especially when insomnia makes you feel dreadful.
Read More
9
Insomnia relief
I wouldn't want to be without melatonin. I've been taking it for years due to awful insomnia caused by menopause, and it really works. Moreover, it has improved the quality of my hair, which had started to thin and fall out. I appreciate iHerb's fast and straightforward service.
Read More
9
Natural relaxation
Excellent! I purchased this for my trouble with falling asleep due to menopause, and it effectively makes me sleepy. I'm not a habitual drinker, but this product has really helped.
Read More
7.5
Deep sleep
I struggle with insomnia due to menopause, but this supplement has helped me fall asleep well and enjoy deep, restful sleep. I prefer 3mg over 5mg and plan to continue using it.
Read More
Frequently Asked Questions
7.5
Effective for sleep
1 people found this helpful
I switched from 5mg to 3mg as I was struggling to sleep because of menopause. Fortunately, 3mg worked well too, allowing me to drift off comfortably within 30 minutes. Previously, 5mg sometimes caused morning headaches depending on my health, but I haven't experienced any with 3mg. This dosage feels just right for me; I highly recommend it, especially when insomnia makes you feel dreadful.
7.5
Helps with insomnia
I purchased this product due to ongoing insomnia associated with menopause. I find that I can naturally fall asleep within an hour of taking it, so I believe it is effective. It also gives me a sense of security, acting as a comforting talisman before sleep. Additionally, the size is easy to drink.
9
Insomnia relief
I wouldn't want to be without melatonin. I've been taking it for years due to awful insomnia caused by menopause, and it really works. Moreover, it has improved the quality of my hair, which had started to thin and fall out. I appreciate iHerb's fast and straightforward service.
9
Sleep improvement
4 people found this helpful
After ten years of insomnia resulting from menopause, I found melatonin to be the most effective solution compared to GABA and tryptophan. For the first time in ages, I experienced actual sleepiness and could return to sleep if I woke during the night. Initially taking vitamin D prior to melatonin may have helped.
7.5
Deep sleep
I struggle with insomnia due to menopause, but this supplement has helped me fall asleep well and enjoy deep, restful sleep. I prefer 3mg over 5mg and plan to continue using it.
6
Youthful energy
3 people found this helpful
Without melatonin, life becomes unbearable, particularly during menopause. I felt that 5mg was too strong for me, causing drowsiness and weakness when waking. On the other hand, 3mg is excellent, and I've been purchasing melatonin here for years—my "vitamin of youth."
7.5
Overall improvement
Your sleep quality enhances, and you'll feel better! Since the onset of menopause, I've faced difficulties sleeping, leading to weakened immunity. After trying melatonin gummy candies, I found I could sleep better. I switched to this supplement type, which is easier to consume, and 3mg works perfectly for me. It’s now an essential supplement for my wellbeing.
8
We explored the role of melatonin in reducing depression and anxiety among postmenopausal women by reviewing multiple randomized controlled trials. Our analysis included five studies with 441 participants, revealing that melatonin significantly lessened symptoms of both depression and anxiety.
This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
This suggests melatonin could be an effective option for managing these emotional struggles during menopause. However, the findings indicate a need for more high-quality research to assess the treatment's long-term safety and efficacy.
9
We evaluated the effects of melatonin treatment on emotion, sleep, and quality of life in 100 healthy perimenopausal women. Participants were divided into two groups: one receiving melatonin and the other a placebo over three cycles.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
After analyzing various hormonal levels and using questionnaires to assess perimenopausal symptoms, sleep quality, anxiety, and mood, we found that melatonin significantly alleviated climacteric symptoms.
Participants reported improved sleep, enhanced mood, and a better overall quality of life without serious side effects.
9
Melatonin reduces menopause symptoms effectively
We explored how a blend of soy isoflavones, 8-prenylnaringenin, and melatonin affects hot flashes in postmenopausal women. Over 12 weeks, 44 participants reported significant reductions in hot flash frequency and improvements in health-related quality of life.
By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
By the end of the study, women experienced notable benefits across various life domains, with a 76.5% decrease in hot flashes and enhanced well-being. This combination could be a promising option for managing menopausal symptoms.
9
We explored the potential benefits of melatonin for treating osteoporosis in different stages of menopause using a rat model.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
In our study, rats were given melatonin or a solvent for eight weeks after undergoing ovariectomy, simulating perimenopausal and postmenopausal conditions.
The results showed that melatonin helped increase bone mass and improve bone metabolism, promoting the growth of bone-forming cells. This suggests melatonin could be a helpful treatment for osteoporosis associated with menopause.
4
Melatonin shows limited menopausal benefits
We examined how melatonin affects menopausal symptoms through a systematic review of eight trials involving over 800 women. While melatonin showed some promise in easing physical symptoms, it didn’t significantly help with sleep quality or broader menopausal issues like mood changes, anxiety, or sexual health. Notably, there were no improvements in weight or hormone levels either. Despite these findings, more extensive research is needed to better understand melatonin's role in menopause management.
References
- Demirhan Kayacik A, İlcioglu K. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials. Arch Womens Ment Health. 2024;27:265. 10.1007/s00737-023-01395-0
- Zhang J, Jiang B. Influence of Melatonin Treatment on Emotion, Sleep, and Life Quality in Perimenopausal Women: A Clinical Study. J Healthc Eng. 2023;2023:2198804. 10.1155/2023/2198804
- Estrugo CP, Rodríguez MT, de Guevara NM, Gómez JG, Ridocci F, et al. Combination of Soy Isoflavones, 8-Prenylnaringenin and Melatonin Improves Hot Flashes and Health-Related Quality of Life Outcomes in Postmenopausal Women: Flavie Study. J Menopausal Med. 2023;29:73. 10.6118/jmm.22034
- Guan H, Kong N, Tian R, Cao R, Liu G, et al. Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis. J Transl Med. 2022;20:132. 10.1186/s12967-022-03341-7
- Treister-Goltzman Y, Peleg R. Melatonin and the health of menopausal women: A systematic review. J Pineal Res. 2021;71:e12743. 10.1111/jpi.12743
- Yi M, Wang S, Wu T, Zhang X, Jiang L, et al. Effects of exogenous melatonin on sleep quality and menopausal symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials. Menopause. 2021;28:717. 10.1097/GME.0000000000001757
- Chojnacki C, Mędrek-Socha M, Konrad P, Chojnacki J, Błońska A. The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia. BMC Womens Health. 2020;20:262. 10.1186/s12905-020-01117-z
- Proserpio P, Marra S, Campana C, Agostoni EC, Palagini L, et al. Insomnia and menopause: a narrative review on mechanisms and treatments. Climacteric. 2020;23:539. 10.1080/13697137.2020.1799973
- Dodda BR, Bondi CD, Hasan M, Clafshenkel WP, Gallagher KM, et al. Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mammary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer. Front Oncol. 2019;9:525. 10.3389/fonc.2019.00525
- Zavodnov OP, Botasheva TL, Vasil'eva VV, Paliyeva NV, Zheleznyakova EV, et al. [Somnological status of women in late reproductive and perimenopausal periods during treatment of sleep disorders using partial light deprivation]. Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119:105. 10.17116/jnevro2019119042105
