Overview
SCIENTIFIC SCORE
Questionable
Based on 31 Researches
6.9
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
Top Medical Research Studies
8
We investigated the link between omega-3 fatty acids and the timing of menopause. Using a Mendelian randomization approach, we analyzed data from thousands of women to assess how different fatty acids influenced reproductive longevity—specifically, the age at menopause.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
Our findings revealed that higher plasma levels of DHA, a type of omega-3, were associated with a delayed onset of menopause. This suggests that increasing DHA could be a potential strategy for extending women's reproductive lifespan.
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9
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
8
We investigated how DHA-enriched fish oil affects cognitive challenges associated with menopause, particularly in female mice carrying the APOE4 gene, known to increase Alzheimer's risk. Our findings suggest that while this fish oil improved recognition memory, it did not significantly enhance spatial working memory.
Furthermore, the fish oil raised levels of DHA and other beneficial compounds in the brain, hinting at its potential protective effects against menopause-related cognitive decline, especially for those at higher risk. Overall, our study indicates a promising role for DHA-rich fish oil in supporting brain health during menopause.
Furthermore, the fish oil raised levels of DHA and other beneficial compounds in the brain, hinting at its potential protective effects against menopause-related cognitive decline, especially for those at higher risk. Overall, our study indicates a promising role for DHA-rich fish oil in supporting brain health during menopause.
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Most Useful Reviews
7.5
Menopause relief
9 people found this helpful
The condition of my skin and hair has improved. Omega-3 PUFAs, which the body cannot synthesise, are essential for various functions. They are particularly important for women during menopause, helping alleviate its symptoms, and reducing menstrual pain. I've noticed a positive effect on my digestive tract as well. After two to three weeks of taking two capsules daily, I experienced noticeable improvements. I will continue this as a preventive measure for my health and well-being.
Read More
9
Symptom alleviation
Omega-3 PUFAs are essential substances that the body cannot produce. During menopause, they alleviate symptoms and reduce the risk of complications like postpartum depression. I only take this brand, as it has shown me the benefits without any fishy aftertaste. I appreciate the positive effects on my menstrual pain too.
Read More
9
Mental enhancement
1 people found this helpful
This omega product is excellent for women in menopause, boosting mental abilities while maintaining appearance. It even helps with the issue of greying hair. I'm pleased it has no fishy smell, making it easier to take regularly.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 31 Researches
6.9
- All Researches
9
We examined the impact of omega 3 fish oil, paired with resistance exercise, on health in postmenopausal women. In our trial, 20 healthy older women took part in either a resistance training program with fish oil or a placebo for eight weeks.
Both groups showed improvements in physical function, but those taking fish oil experienced a notable boost in handgrip strength and lower blood pressure and inflammatory markers.
This suggests that fish oil could enhance muscle function and reduce health risks for women navigating menopause.
Both groups showed improvements in physical function, but those taking fish oil experienced a notable boost in handgrip strength and lower blood pressure and inflammatory markers.
This suggests that fish oil could enhance muscle function and reduce health risks for women navigating menopause.
Read More
9
We explored how omega-3 polyunsaturated fatty acids (PUFA) affect mood changes associated with menopause in ovariectomized rats. Our study revealed that menopause led to anxiety and depression-like behaviors, driven by increased neuroinflammation in the brain.
However, we found that omega-3 supplementation helped shift the brain's inflammatory response towards a healthier balance. The omega-3s not only assisted in reducing the negative mood symptoms but also promoted protective effects against neuroinflammation.
Overall, while omega-3 fatty acids show promise, more research is needed to fully understand their benefits for menopause-related issues.
However, we found that omega-3 supplementation helped shift the brain's inflammatory response towards a healthier balance. The omega-3s not only assisted in reducing the negative mood symptoms but also promoted protective effects against neuroinflammation.
Overall, while omega-3 fatty acids show promise, more research is needed to fully understand their benefits for menopause-related issues.
Read More
9
We examined how omega-3 polyunsaturated fatty acids (n-3 PUFA) could protect against vascular issues linked to menopause using an ovariectomized rat model.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
In our study, we found that n-3 PUFA supplementation helped maintain baroreflex sensitivity, which typically declines after ovariectomy.
Additionally, the central arterial pressure profile remained stable in treated rats, showing a potential protective effect against postmenopausal vascular issues. This suggests that omega-3 fish oil may offer therapeutic benefits during menopause.
Read More
9
We explored the relationship between eicosapentaenoic acid (EPA) intake and estradiol levels in women, specifically focusing on its effects during menopause. The study utilized data from the National Health and Nutrition Examination Survey, which included dietary interviews and serum estradiol level measurements.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
Our findings highlighted that higher intakes of EPA were associated with increased estradiol levels in both menopausal and non-menopausal women. Importantly, we noted that EPA intake above a certain threshold was linked to these hormonal changes.
This research suggests that incorporating more EPA into the diet could play a role in regulating estradiol levels, which is particularly beneficial for women's reproductive health during and after menopause. Understanding these connections helps emphasize the importance of nutrition in hormone regulation.
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9
We explored the relationship between docosahexaenoic acid (DHA), a type of omega-3 fatty acid, and breast density among postmenopausal women, particularly focusing on those who are obese. Our study aimed to understand how DHA might differentially affect breast density in obese versus nonobese women, using a method called iTRAQ to analyze plasma samples over two years.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
During the study, we identified 173 proteins in the plasma samples. Some of these proteins showed different levels of expression based on whether women were obese or lean. Notably, proteins like the vitamin D binding protein and fibronectin were altered, which suggests a connection between DHA intake and reduced inflammation in obese women.
Our findings indicated that there is an inverse relationship between DHA levels and breast density specifically in postmenopausal obese women. This suggests that greater DHA intake could potentially reduce breast density and may decrease breast cancer risk in this demographic. However, it’s important to note that the effect was not observed in nonobese women.
Overall, this research highlights DHA's role in impacting breast health during menopause, particularly for those with obesity. It opens up further discussions on how dietary changes could play a role in cancer prevention strategies for women going through menopause.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Menopause relief
9 people found this helpful
The condition of my skin and hair has improved. Omega-3 PUFAs, which the body cannot synthesise, are essential for various functions. They are particularly important for women during menopause, helping alleviate its symptoms, and reducing menstrual pain. I've noticed a positive effect on my digestive tract as well. After two to three weeks of taking two capsules daily, I experienced noticeable improvements. I will continue this as a preventive measure for my health and well-being.
Read More
9
Symptom alleviation
Omega-3 PUFAs are essential substances that the body cannot produce. During menopause, they alleviate symptoms and reduce the risk of complications like postpartum depression. I only take this brand, as it has shown me the benefits without any fishy aftertaste. I appreciate the positive effects on my menstrual pain too.
Read More
9
Mental enhancement
1 people found this helpful
This omega product is excellent for women in menopause, boosting mental abilities while maintaining appearance. It even helps with the issue of greying hair. I'm pleased it has no fishy smell, making it easier to take regularly.
Read More
6
Osteoporosis prevention
1 people found this helpful
The taste is pleasant! Omega-3 fatty acids help prevent osteoporosis in menopausal women. They also reduce joint inflammation, swelling, and stiffness associated with rheumatoid arthritis. Furthermore, Omega-3s can alleviate menstrual cramps, providing relief during that time. I've found this product beneficial for managing these issues.
Read More
Frequently Asked Questions
7.5
Menopause relief
9 people found this helpful
The condition of my skin and hair has improved. Omega-3 PUFAs, which the body cannot synthesise, are essential for various functions. They are particularly important for women during menopause, helping alleviate its symptoms, and reducing menstrual pain. I've noticed a positive effect on my digestive tract as well. After two to three weeks of taking two capsules daily, I experienced noticeable improvements. I will continue this as a preventive measure for my health and well-being.
9
Symptom alleviation
Omega-3 PUFAs are essential substances that the body cannot produce. During menopause, they alleviate symptoms and reduce the risk of complications like postpartum depression. I only take this brand, as it has shown me the benefits without any fishy aftertaste. I appreciate the positive effects on my menstrual pain too.
6
Osteoporosis prevention
1 people found this helpful
The taste is pleasant! Omega-3 fatty acids help prevent osteoporosis in menopausal women. They also reduce joint inflammation, swelling, and stiffness associated with rheumatoid arthritis. Furthermore, Omega-3s can alleviate menstrual cramps, providing relief during that time. I've found this product beneficial for managing these issues.
9
Mental enhancement
1 people found this helpful
This omega product is excellent for women in menopause, boosting mental abilities while maintaining appearance. It even helps with the issue of greying hair. I'm pleased it has no fishy smell, making it easier to take regularly.
References
- Fan R, Kim J, Kim YC, Chung S. Effects of Fish Oil with Heat Treatment on Obesity, Inflammation, and Gut Microbiota in Ovariectomized Mice. Nutrients. 2025;17. doi:10.3390/nu17030549
- Gao H, Ying Y, Sun J, Huang Y, Li X, et al. Genetically Determined Plasma Docosahexaenoic Acid Showed a Causal Association with Female Reproductive Longevity-Related Phenotype: A Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16234103
- Lee SR, Directo D. Fish Oil Supplementation with Resistance Exercise Training Enhances Physical Function and Cardiometabolic Health in Postmenopausal Women. Nutrients. 2023;15. doi:10.3390/nu15214516
- Feehan O, Magee PJ, Pourshahidi LK, Armstrong DJ, Slevin MM, et al. Associations of long chain polyunsaturated fatty acids with bone mineral density and bone turnover in postmenopausal women. Eur J Nutr. 2023;62:95. doi:10.1007/s00394-022-02933-9
- Decandia D, Landolfo E, Sacchetti S, Gelfo F, Petrosini L, et al. n-3 PUFA Improve Emotion and Cognition during Menopause: A Systematic Review. Nutrients. 2022;14. doi:10.3390/nu14091982
- Pontifex MG, Martinsen A, Saleh RNM, Harden G, Fox C, et al. DHA-Enriched Fish Oil Ameliorates Deficits in Cognition Associated with Menopause and the Genotype in Rodents. Nutrients. 2022;14. doi:10.3390/nu14091698
- Félix-Soriano E, Martínez-Gayo A, Cobo MJ, Pérez-Chávez A, Ibáñez-Santos J, et al. Effects of DHA-Rich n-3 Fatty Acid Supplementation and/or Resistance Training on Body Composition and Cardiometabolic Biomarkers in Overweight and Obese Post-Menopausal Women. Nutrients. 2021;13. doi:10.3390/nu13072465
- Purzand B, Rokhgireh S, Shabani Zanjani M, Eshraghi N, Mohamadianamiri M, et al. The comparison of the effect of soybean and fish oil on supplementation on menopausal symptoms in postmenopausal women: A randomized, double-blind, placebo-controlled trial. Complement Ther Clin Pract. 2020;41:101239. doi:10.1016/j.ctcp.2020.101239
- Wu B, Song Q, Zhang Y, Wang C, Yang M, et al. Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization. Lipids Health Dis. 2020;19:4. doi:10.1186/s12944-020-1185-2
- Mohammady M, Janani L, Jahanfar S, Mousavi MS. Effect of omega-3 supplements on vasomotor symptoms in menopausal women: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018;228:295. doi:10.1016/j.ejogrb.2018.07.008
- Cianci A, Maiolino L, Giunta G, Rapisarda AMC, Di Mauro P, et al. Neurovegetative disorders of perimenopausal women treated with docosahexaenoic acid (DHA, 625 mg). Gynecol Endocrinol. 2017;33:980. doi:10.1080/09513590.2017.1334200
- Fonolla-Joya J, Reyes-García R, García-Martín A, López-Huertas E, Muñoz-Torres M. Daily Intake of Milk Enriched with n-3 Fatty Acids, Oleic Acid, and Calcium Improves Metabolic and Bone Biomarkers in Postmenopausal Women. J Am Coll Nutr. 2016;35:529.
- Alves Luzia L, Mendes Aldrighi J, Teixeira Damasceno NR, Rodrigues Sampaio G, Aparecida Manólio Soares R, et al. FISH OIL AND VITAMIN E CHANGE LIPID PROFILES AND ANTI-LDL-ANTIBODIES IN TWO DIFFERENT ETHNIC GROUPS OF WOMEN TRANSITIONING THROUGH MENOPAUSE. Nutr Hosp. 2015;32:165. doi:10.3305/nh.2015.32.1.9079
- Losurdo P, Grillo A, Panizon E, Zanetti M, Bardelli M, et al. Baroreflex sensitivity and central hemodynamics after omega-3 polyunsaturated fatty acids supplementation in an animal model of menopause. Vascul Pharmacol. 2015;71:65. doi:10.1016/j.vph.2014.12.005
- Tardivo AP, Nahas-Neto J, Orsatti CL, Dias FB, Poloni PF, et al. Effects of omega-3 on metabolic markers in postmenopausal women with metabolic syndrome. Climacteric. 2015;18:290. doi:10.3109/13697137.2014.981521
- Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-LaForce C, et al. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements. Am J Obstet Gynecol. 2014;210:244.e1. doi:10.1016/j.ajog.2013.11.016
- Guo L, Nan Y, Liang K, Yao L, Li J. Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women. Front Nutr. 2024;11:1500705. doi:10.3389/fnut.2024.1500705
- So J, Yao JH, Magadmi R, Matthan NR, Lamon-Fava S. Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation. Prostaglandins Leukot Essent Fatty Acids. 2024;203:102655. doi:10.1016/j.plefa.2024.102655
- Putti JS, Engers VK, Heemann FM, Salomon TB, Benfato MS, et al. Effects of lipoic acid and ω-3 long-chain polyunsaturated fatty acids on the kidney in the ovariectomized rat model of menopause. Nutrition. 2019;66:173. doi:10.1016/j.nut.2019.05.003
- Marinho PM, Salomon TB, Andrade AS, Behling CS, Putti JS, et al. The effect of n-3 long-chain polyunsaturated fatty acids and lipoic acid on the heart in the ovariectomized rat model of menopause. Free Radic Res. 2019;53:669. doi:10.1080/10715762.2019.1620938
- Abshirini M, Siassi F, Koohdani F, Qorbani M, Khosravi S, et al. Higher intake of dietary n-3 PUFA and lower MUFA are associated with fewer menopausal symptoms. Climacteric. 2019;22:195. doi:10.1080/13697137.2018.1547700
- Schüller ÁK, Mena Canata DA, Hackenhaar FS, Engers VK, Heemann FM, et al. Effects of lipoic acid and n-3 long-chain polyunsaturated fatty acid on the liver ovariectomized rat model of menopause. Pharmacol Rep. 2018;70:263. doi:10.1016/j.pharep.2017.10.006
- Dong H, Hutchins-Wiese H, Kleppinger A, Annis K, Liva E, et al. Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Bone Turnover in Older Women. Int J Vitam Nutr Res. 2014;84:124. doi:10.1024/0300-9831/a000199
- Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman M, et al. Efficacy of omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause. 2014;21:347. doi:10.1097/GME.0b013e31829e40b8
- Hutchins-Wiese HL, Kleppinger A, Annis K, Liva E, Lammi-Keefe CJ, et al. The impact of supplemental n-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women. J Nutr Health Aging. 2013;17:76. doi:10.1007/s12603-012-0415-3
- Scuderi G, Contestabile MT, Gagliano C, Iacovello D, Scuderi L, et al. Effects of phytoestrogen supplementation in postmenopausal women with dry eye syndrome: a randomized clinical trial. Can J Ophthalmol. 2012;47:489. doi:10.1016/j.jcjo.2012.08.019
- Wattanathorn J, Thukham-Mee W. Omega-3-Rich Tuna Oil Derived from By-Products of the Canned Tuna Industry Enhances Memory in an Ovariectomized Rat Model of Menopause. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13060637
- Konuri A, Bhat KMR, Rai KS, Gourishetti K, Phaneendra M YS. Supplementation of fenugreek with choline-docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats. Anat Sci Int. 2021;96:197. doi:10.1007/s12565-020-00574-8
- Sun YW, Xu H, Benitez G, Chen KM, Stanley A, et al. Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women. J Proteome Res. 2019;18:3461. doi:10.1021/acs.jproteome.9b00356
- Sparkes C, Gibson R, Sinclair A, Else PL, Meyer BJ. Effect of Low Dose Docosahexaenoic Acid-Rich Fish Oil on Plasma Lipids and Lipoproteins in Pre-Menopausal Women: A Dose⁻Response Randomized Placebo-Controlled Trial. Nutrients. 2018;10. doi:10.3390/nu10101460
- Jin Y, Kim TH, Park Y. Association between erythrocyte levels of n-3 polyunsaturated fatty acids and depression in postmenopausal women using or not using hormone therapy. Menopause. 2016;23:1012. doi:10.1097/GME.0000000000000667
