Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
Top Medical Research Studies
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
9
We investigated how the intake of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, might affect the frequency of migraine attacks. In a study involving 105 migraine patients aged 15 to 50, we examined their usual dietary habits through a food frequency questionnaire and tracked their migraine occurrences over a month.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Read More
Most Useful Reviews
9
Migraine relief
Taking these capsules regularly has normalised my sleep and significantly improved my migraines. When I feel symptoms starting, I take my pills, add extra magnesium, and my migraine typically subsides within hours, compared to previously being incapacitated for half a day. My PMS and menstruation have also become much more manageable with regular magnesium intake, and my chronic nasopharynx pain has lessened. I've also been taking omega-3 and other supplements, which may contribute. I've experienced no side effects; the quality is excellent and natural.
Read More
9
Migraine management
These capsules have normalised my sleep and improved my migraines significantly. When I feel the beginnings of a migraine, I take my usual pills and some extra magnesium, and the migraine usually eases within a few hours. In the past, I would be out of action for much longer. Additionally, my PMS and menstruation are much easier to handle with consistent magnesium intake, and I have experienced no side effects. Overall, the quality and natural ingredients are superb.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.2
- All Researches
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
9
We investigated how the intake of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, might affect the frequency of migraine attacks. In a study involving 105 migraine patients aged 15 to 50, we examined their usual dietary habits through a food frequency questionnaire and tracked their migraine occurrences over a month.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Our findings revealed a notable trend: lower consumption of EPA was tied to an increased number of migraine attacks. Specifically, participants with reduced EPA intake experienced a higher frequency of migraines, with data indicating a significant statistical relationship. We also found that this connection held true for both men and women alike, emphasizing the potential importance of dietary choices in managing migraines.
Conversely, we did not observe any significant link between saturated fatty acids (SFA) and migraine frequency, suggesting that not all dietary fats impact migraines the same way. Overall, our results point to a promising association between omega-3 fatty acids, particularly EPA, and reduced migraine attacks, inviting further research to deepen our understanding of this relationship.
Read More
9
We conducted a randomized trial to understand how modifying dietary omega-3 and omega-6 fatty acids influences chronic headache conditions, particularly migraines. Patients with daily headaches followed two different dietary plans: one that included a high level of omega-3 and a low level of omega-6, and another that just reduced omega-6 intake. Over 12 weeks, we gathered both clinical and biochemical data to evaluate the outcomes.
Interestingly, the results highlighted that the group consuming more omega-3 fatty acids had significant improvements in their headache symptoms. They reported fewer headache days per month and spent less time each day suffering from headaches compared to those who only lowered their omega-6 intake. Additionally, we noted notable changes at the biochemical level, indicating increased levels of certain markers related to pain relief in the higher omega-3 group.
Our findings suggest that enhancing omega-3 intake while reducing omega-6 can lead to better management of chronic headaches, altering pain-related lipid mediators and ultimately improving quality of life for those suffering from such conditions.
Interestingly, the results highlighted that the group consuming more omega-3 fatty acids had significant improvements in their headache symptoms. They reported fewer headache days per month and spent less time each day suffering from headaches compared to those who only lowered their omega-6 intake. Additionally, we noted notable changes at the biochemical level, indicating increased levels of certain markers related to pain relief in the higher omega-3 group.
Our findings suggest that enhancing omega-3 intake while reducing omega-6 can lead to better management of chronic headaches, altering pain-related lipid mediators and ultimately improving quality of life for those suffering from such conditions.
Read More
8
We examined the effectiveness of daily 2000 mg eicosapentaenoic acid (EPA) supplementation in individuals suffering from chronic migraines. In a randomized, double-blind study, participants received either EPA or a placebo for eight weeks.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Migraine relief
Taking these capsules regularly has normalised my sleep and significantly improved my migraines. When I feel symptoms starting, I take my pills, add extra magnesium, and my migraine typically subsides within hours, compared to previously being incapacitated for half a day. My PMS and menstruation have also become much more manageable with regular magnesium intake, and my chronic nasopharynx pain has lessened. I've also been taking omega-3 and other supplements, which may contribute. I've experienced no side effects; the quality is excellent and natural.
Read More
9
Migraine management
These capsules have normalised my sleep and improved my migraines significantly. When I feel the beginnings of a migraine, I take my usual pills and some extra magnesium, and the migraine usually eases within a few hours. In the past, I would be out of action for much longer. Additionally, my PMS and menstruation are much easier to handle with consistent magnesium intake, and I have experienced no side effects. Overall, the quality and natural ingredients are superb.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
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- Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. doi:10.1111/head.14808
- Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. doi:10.1016/j.bbi.2024.03.019
- Tseng PT, Zeng BY, Chen JJ, Kuo CH, Zeng BS, et al. High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis. Adv Nutr. 2024;15:100163. doi:10.1016/j.advnut.2023.100163
- Djalali M, Talebi S, Djalali E, Abdolahi M, Travica N, et al. The effect of omega-3 fatty acids supplementation on inflammatory biomarkers in subjects with migraine: a randomized, double-blind, placebo-controlled trial. Immunopharmacol Immunotoxicol. 2023;45:565. doi:10.1080/08923973.2023.2196600
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- Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. doi:10.1136/bmj.n1448
- Abdolahi M, Karimi E, Sarraf P, Tafakhori A, Siri G, et al. The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial. BMC Res Notes. 2021;14:283. doi:10.1186/s13104-021-05700-x
- Cardia L, Calapai F, Mondello C, Quattrone D, Elisa Sorbara E, et al. Clinical use of omega-3 fatty acids in migraine: A narrative review. Medicine (Baltimore). 2020;99:e22253. doi:10.1097/MD.0000000000022253
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- Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. doi:10.2174/1871530319666190212170140
- Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. doi:10.1016/j.plefa.2018.06.008
- Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. doi:10.2174/1871527317666171213154749
- Maghsoumi-Norouzabad L, Mansoori A, Abed R, Shishehbor F. Effects of omega-3 fatty acids on the frequency, severity, and duration of migraine attacks: A systematic review and meta-analysis of randomized controlled trials. Nutr Neurosci. 2018;21:614. doi:10.1080/1028415X.2017.1344371
- Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. doi:10.1007/s00251-017-0992-8
- Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. doi:10.1080/1028415X.2016.1266133
- Pradalier A, Bakouche P, Baudesson G, Delage A, Cornaille-Lafage G, et al. Failure of omega-3 polyunsaturated fatty acids in prevention of migraine: a double-blind study versus placebo. Cephalalgia. 2001;21:818.
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- Mann JD, Faurot KR, MacIntosh B, Palsson OS, Suchindran CM, et al. A sixteen-week three-armed, randomized, controlled trial investigating clinical and biochemical effects of targeted alterations in dietary linoleic acid and n-3 EPA+DHA in adults with episodic migraine: Study protocol. Prostaglandins Leukot Essent Fatty Acids. 2018;128:41. doi:10.1016/j.plefa.2017.11.002
- Sadeghi O, Maghsoudi Z, Khorvash F, Ghiasvand R, Askari G. The relationship between different fatty acids intake and frequency of migraine attacks. Iran J Nurs Midwifery Res. 2015;20:334.
- Ramsden CE, Faurot KR, Zamora D, Suchindran CM, MacIntosh BA, et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial. Pain. 2013;154:2441. doi:10.1016/j.pain.2013.07.028
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