Last update
3/15/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Calcium (as Dibasic Calcium Phosphate)
32 mg
2%
5-HTP (5-Hydroxytryptophan)[from Griffonia simplicifolia) (seed)
100 mg
*
Top Medical Research Studies
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
Most Useful Reviews
7.5
Normal mood and sleep
31 people found this helpful
A miracle for depression, sleep issues, and anxiety! This supplement has been transformative. Since entering menopause, I've struggled with sleep, but after taking it, I fell asleep quickly and stayed that way. It’s made me feel balanced and normal without the sluggishness caused by prescription drugs. I can fall asleep easily if I wake up at night, which is a blessing!
Read More
7.5
Reduced frustration
4 people found this helpful
I'm using this to manage the frustrations that come with menopause. When I feel overwhelmed, I take a tablet to help me relax. I noticed that taking one before bed has improved my sleep. The long-lasting ingredients seem effective over time.
Read More
9
Anxiety relief
3 people found this helpful
A game changer for my "mental" pause! I was searching for the right product to help with the anxiety from menopause, and I've finally found it! Now I feel calm and energetic. It truly works for me, and I hope it helps you too!
Read More
Medical Researches
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
0
- All Researches
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Normal mood and sleep
31 people found this helpful
A miracle for depression, sleep issues, and anxiety! This supplement has been transformative. Since entering menopause, I've struggled with sleep, but after taking it, I fell asleep quickly and stayed that way. It’s made me feel balanced and normal without the sluggishness caused by prescription drugs. I can fall asleep easily if I wake up at night, which is a blessing!
Read More
7.5
Reduced frustration
4 people found this helpful
I'm using this to manage the frustrations that come with menopause. When I feel overwhelmed, I take a tablet to help me relax. I noticed that taking one before bed has improved my sleep. The long-lasting ingredients seem effective over time.
Read More
9
Anxiety relief
3 people found this helpful
A game changer for my "mental" pause! I was searching for the right product to help with the anxiety from menopause, and I've finally found it! Now I feel calm and energetic. It truly works for me, and I hope it helps you too!
Read More
6
Improved sleep quality
1 people found this helpful
After entering menopause, I found it challenging to fall asleep. This product promotes a calm and relaxed mood. I am eager to continue taking it to increase serotonin and enhance my sleep quality. The particles are small and easy to swallow, so I will carry on with it.
Read More
7.5
Balanced emotions
2 people found this helpful
Nausea at first, but it works well now. I occasionally take this for menopause symptoms, as I declined hormone treatment from my doctor. Initially, I experienced nausea, but now I take it with food, and it helps restore my balance quickly.
Read More
Frequently Asked Questions
7.5
Reduced frustration
4 people found this helpful
I'm using this to manage the frustrations that come with menopause. When I feel overwhelmed, I take a tablet to help me relax. I noticed that taking one before bed has improved my sleep. The long-lasting ingredients seem effective over time.
6
Improved sleep quality
1 people found this helpful
After entering menopause, I found it challenging to fall asleep. This product promotes a calm and relaxed mood. I am eager to continue taking it to increase serotonin and enhance my sleep quality. The particles are small and easy to swallow, so I will carry on with it.
0
5-HTP ineffective for hot flashes
We aimed to find out how effective 5-hydroxytryptophan (5-HTP) is for reducing hot flashes in menopausal women.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
In a double-blind study involving 24 postmenopausal participants, we divided the group to receive either 5-HTP or a placebo.
Unfortunately, our results showed no significant difference in hot flash frequency between the two groups after treatment.
Thus, it appears that 5-HTP at the tested dose does not effectively alleviate hot flashes, making further research necessary.
References
- Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 2010;65:383. 10.1016/j.maturitas.2009.11.025
Data last updated:
