' 
SCIENTIFIC SCORE
Possibly Effective
Based on 36 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%*
Vitamin D3 (as Cholecalciferol)
10 mcg (400 IU)
50%
Calcium (as Calcium Carbonate)
600 mg
46%
Top Medical Research Studies
9
Calcium and vitamin D reduce fractures
Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation.
Significant relevance for osteoporosis
We examined a collection of randomized controlled trials to determine the impact of calcium plus vitamin D supplementation on fracture prevention.
The results revealed a promising 15% reduction in total fractures and a remarkable 30% drop in hip fractures among those taking these supplements.
This convincing evidence supports the recommendation of calcium and vitamin D for reducing fracture risk, especially in older adults, whether living at home or in care facilities.
The results revealed a promising 15% reduction in total fractures and a remarkable 30% drop in hip fractures among those taking these supplements.
This convincing evidence supports the recommendation of calcium and vitamin D for reducing fracture risk, especially in older adults, whether living at home or in care facilities.
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9
Calcium, Vitamin D, Zinc aids osteoporosis
Effects of a calcium/vitamin D/Zinc combination on anti-osteoporosis in ovariectomized rats.
Relevant and promising findings
We explored how the combination of calcium, vitamin D, and zinc impacts osteoporosis in ovariectomized rats. Using a well-structured study design, we divided 49 rats into various groups to compare results against a control.
Our findings suggest that this combined supplement helps enhance calcium absorption and reduces bone deterioration by lowering specific osteoporosis-related factors. This could point toward a potential alternative treatment for postmenopausal osteoporosis, though further research in humans is necessary.
Our findings suggest that this combined supplement helps enhance calcium absorption and reduces bone deterioration by lowering specific osteoporosis-related factors. This could point toward a potential alternative treatment for postmenopausal osteoporosis, though further research in humans is necessary.
Read More
9
Vitamin D derivatives enhance bone health
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities.
Significant benefits for osteoporosis.
We looked into the potential effects of vitamin D3, particularly its derivatives, on osteoporosis. Recent research highlights how modifications to the A-ring of 1α,25-dihydroxyvitamin D can enhance its binding to the vitamin D receptor. This change not only boosts the vitamin's effectiveness but also helps it resist breakdown in the body, making it stay active for longer periods.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
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Most Useful Reviews
8.8
Effective for osteoporosis
Capsules are preferable. I have osteoporosis, and my doctor recommended avoiding hard tablets. This product also provides a good dose of vitamin D, and the combination has been beneficial for me.
Read More
9.5
Reduces fracture risk
This product is very effective in reducing the risk of osteoporosis fractures.
Read More
8.8
Improved wellbeing
As a lady of a certain age, I've developed various aches and pains, and my doctor has raised concerns about osteoporosis. He recommended a twice daily Calcium/D tablet. After four months of regular use, I feel better and am moving more freely. My calcium levels are steadily increasing, and my doctor and I are pleased with my progress.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 36 Researches
7.8
- All Researches
9.5
Vitamin D3 aids osteoporosis prevention
IgG4-RD-Associated Mikulicz Syndrome Without Classic Systemic Involvement-A Case Report.
Highlights role in osteoporosis management
We looked into the effects of vitamin D3 on osteoporosis management, particularly in relation to glucocorticoid-induced complications. In a recent case involving an 85-year-old patient with IgG4-related disease, vitamin D3 was used alongside prednisone and azathioprine. The goal was to prevent bone density loss often seen with steroid treatments.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
Read More
9
Calcium, Vitamin D, Zinc aids osteoporosis
Effects of a calcium/vitamin D/Zinc combination on anti-osteoporosis in ovariectomized rats.
Relevant and promising findings
We explored how the combination of calcium, vitamin D, and zinc impacts osteoporosis in ovariectomized rats. Using a well-structured study design, we divided 49 rats into various groups to compare results against a control.
Our findings suggest that this combined supplement helps enhance calcium absorption and reduces bone deterioration by lowering specific osteoporosis-related factors. This could point toward a potential alternative treatment for postmenopausal osteoporosis, though further research in humans is necessary.
Our findings suggest that this combined supplement helps enhance calcium absorption and reduces bone deterioration by lowering specific osteoporosis-related factors. This could point toward a potential alternative treatment for postmenopausal osteoporosis, though further research in humans is necessary.
Read More
9
Teriparatide enhances bone density
Teriparatide Treatment in Patients with Pregnancy- and Lactation-Associated Osteoporosis.
Significant relevance to osteoporosis treatment
We examined the effects of teriparatide combined with calcium and vitamin D versus standard calcium and vitamin D treatment on bone health in premenopausal women with pregnancy- and lactation-associated osteoporosis.
In our study, 19 women received teriparatide, while 8 only received calcium and vitamin D over 24 months. Results showed that those treated with teriparatide experienced significantly greater increases in bone mineral density at the lumbar spine after 12 and 24 months, indicating better bone health outcomes.
Overall, we found that teriparatide treatment substantially benefits women facing this rare condition.
In our study, 19 women received teriparatide, while 8 only received calcium and vitamin D over 24 months. Results showed that those treated with teriparatide experienced significantly greater increases in bone mineral density at the lumbar spine after 12 and 24 months, indicating better bone health outcomes.
Overall, we found that teriparatide treatment substantially benefits women facing this rare condition.
Read More
9
Nanoscale calcium salts improve osteoporosis
Nanoscale Calcium Salt-Based Formulations As Potential Therapeutics for Osteoporosis.
High relevance for osteoporosis treatment
We focused on the potential of nanoscale calcium salt formulations combined with vitamin D and natural minerals to treat osteoporosis. In our study, these innovative formulations showed promising results by enhancing bone density and reducing bone resorption in osteoporotic rats.
The tablets increased osteoblast activity and decreased osteoclast activity without causing toxicity. This dual action positions these calcium salt nanocomposites as a novel approach in osteoporosis management, offering a safer alternative to traditional treatments.
The tablets increased osteoblast activity and decreased osteoclast activity without causing toxicity. This dual action positions these calcium salt nanocomposites as a novel approach in osteoporosis management, offering a safer alternative to traditional treatments.
Read More
9
Calcium and vitamin D enhance treatment
Vitamin D and Calcium Addition during Denosumab Therapy over a Period of Four Years Significantly Improves Lumbar Bone Mineral Density in Japanese Osteoporosis Patients.
Highly relevant to osteoporosis care
We explored how adding vitamin D and calcium to denosumab therapy impacts bone health in patients with primary osteoporosis over four years.
The study involved two groups: one receiving just denosumab and another receiving denosumab with vitamin D and calcium.
Both groups saw improvements in bone health, but the combination group showed significant gains in hip bone density at 12 months and lumbar bone density from 24 to 48 months.
This suggests that ongoing vitamin D and calcium supplementation is beneficial alongside denosumab treatment.
The study involved two groups: one receiving just denosumab and another receiving denosumab with vitamin D and calcium.
Both groups saw improvements in bone health, but the combination group showed significant gains in hip bone density at 12 months and lumbar bone density from 24 to 48 months.
This suggests that ongoing vitamin D and calcium supplementation is beneficial alongside denosumab treatment.
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User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Effective for osteoporosis
Capsules are preferable. I have osteoporosis, and my doctor recommended avoiding hard tablets. This product also provides a good dose of vitamin D, and the combination has been beneficial for me.
9.5
Reduces fracture risk
This product is very effective in reducing the risk of osteoporosis fractures.
8.8
Improved wellbeing
As a lady of a certain age, I've developed various aches and pains, and my doctor has raised concerns about osteoporosis. He recommended a twice daily Calcium/D tablet. After four months of regular use, I feel better and am moving more freely. My calcium levels are steadily increasing, and my doctor and I are pleased with my progress.
Read More
8.8
Strengthens bones effectively
With over 50 years of experience, this dietary supplement strengthens bones and reduces the risk of osteoporosis. It contains natural colours, no artificial flavours, preservatives, or gluten. Regular intake of calcium and vitamin D, alongside a well-balanced diet, can indeed help lower the risk of osteoporosis, and this product meets our strict standards of purity and potency.
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7.5
Good vitamin D source
I have osteoporosis, and my doctor suggested avoiding hard tablets. This option provides a good dose of vitamin D, which has worked well for me.
