Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
250 mg
60%

Top Medical Research Studies

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More

Most Useful Reviews

9
Significant improvement
28 people found this helpful
I love Nature Made Magnesium; it really helps with my migraines. I've suffered from migraines since I was 16 and have tried various medications with no relief. A friend suggested magnesium, and I've been taking it for just over a month now. My migraines have lessened, and I would recommend it to anyone looking for help with their migraines. Nature Made is my go-to brand.
Read More
7.5
Significantly reduced migraines
19 people found this helpful
I take this to ward off migraines! After reading that magnesium is beneficial for constant migraines, I began using this product. I've only had about two migraines in six months. While results may vary individually, it is worth trying if you experience constant migraines. I take this along with zinc.
Read More
9
No atypical migraines
6 people found this helpful
Works wonders for my RLS and atypical migraines. Despite being sceptical about supplements, after a prescription worsened my RLS, I decided to try magnesium. To my surprise, I found it beneficial. As a bonus, I have not had an atypical migraine since starting these. They are easy to swallow, inexpensive, and effective—a win-win for me.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
  • All Researches
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More
We examined how magnesium oxide (MgO), both alone and with riboflavin, helps prevent migraines in pregnant individuals. This retrospective study included 203 patients treated between 2015 and 2020, analyzing outcomes such as migraine frequency, severity, and duration.

We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
We examined the potential role of magnesium, along with other natural ingredients, in reducing the severity and frequency of symptoms associated with vestibular migraine (VM). This observational study involved a questionnaire-based approach where we encouraged patients to consider lifestyle changes alongside an over-the-counter supplement containing magnesium and other components.

Over a three-month period, we collected data from 82 participants, focusing on symptom severity using various assessment tools. We found that there was a notable decrease in the reported severity and frequency of VM symptoms. Patients indicated improvements in their discomfort levels, with around 50% reporting better outcomes.

While magnesium was part of a combination therapy, our findings suggest that nonprescription treatments can significantly impact VM symptoms. This offers a positive outlook for individuals seeking alternative management strategies for their migraines without relying solely on prescription medications.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 14 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Significant improvement
28 people found this helpful
I love Nature Made Magnesium; it really helps with my migraines. I've suffered from migraines since I was 16 and have tried various medications with no relief. A friend suggested magnesium, and I've been taking it for just over a month now. My migraines have lessened, and I would recommend it to anyone looking for help with their migraines. Nature Made is my go-to brand.
Read More
7.5
Significantly reduced migraines
19 people found this helpful
I take this to ward off migraines! After reading that magnesium is beneficial for constant migraines, I began using this product. I've only had about two migraines in six months. While results may vary individually, it is worth trying if you experience constant migraines. I take this along with zinc.
Read More
9
No atypical migraines
6 people found this helpful
Works wonders for my RLS and atypical migraines. Despite being sceptical about supplements, after a prescription worsened my RLS, I decided to try magnesium. To my surprise, I found it beneficial. As a bonus, I have not had an atypical migraine since starting these. They are easy to swallow, inexpensive, and effective—a win-win for me.
Read More
9
Effective relief
5 people found this helpful
I bought this for relief from my migraines in combination with B12. I am very satisfied with the results so far! I highly recommend these vitamins.
Read More
6
Good value
28 people found this helpful
This type of magnesium isn't the best absorbed, yet it helps enough with migraine prevention. There are no side effects, making it good value for the price.
Read More

Frequently Asked Questions

9
Migraine management
This is the best magnesium I've purchased. Although the pills are large and hard to swallow, they significantly improve my migraines, help me sleep well, and assist with constipation. I take two before bed every night.
7.5
Calming effect
I take magnesium for migraine relief and to enhance my mood and well-being. I find it effective, providing a calming effect.
7.5
Migraine relief
23 people found this helpful
Magnesium is essential for the body's functions, including energy metabolism and mood regulation. I take a Nature Made Magnesium Tablet at night, which relaxes me and has eliminated my headaches related to dystonia. The tablets are small, and I experienced no gastrointestinal side effects. My girlfriend now takes it too and appreciates how beneficial magnesium can be for health.
7.5
Migraine and constipation
I started taking magnesium for migraines, and it unexpectedly cleared up years of constipation as well. The pills are easy to swallow and of high quality.
6
Migraine support
The ingredient quality is good, but I might choose a different magnesium as this one is reportedly poorly absorbed. It was intended for my migraines and has also helped with constipation.
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
We explored the role of magnesium as a potential treatment for migraines through a review of existing literature. Migraines can be intense and debilitating, impacting many individuals' day-to-day lives. Our focus was on understanding whether supplementing magnesium could help in preventing or managing these attacks.

Some studies suggest that low levels of magnesium may be linked to more frequent or severe migraine episodes. When people suffer from migraines, inflammation and oxidative stress might contribute to their pain, and magnesium appears to play a role in helping regulate these processes. By supporting brain health and energy metabolism, magnesium could potentially mitigate some of the triggers associated with migraines.

Although the evidence does point to benefits from magnesium supplementation, we noted that more extensive, well-controlled studies are necessary to draw firm conclusions. Overall, while magnesium shows promise, it may not be a standalone solution and could work best in combination with other treatments.
We observed that magnesium is often mentioned in discussions about effective treatments for migraines. This mineral plays a vital role in many bodily functions, and its potential to alleviate migraine symptoms is supported by anecdotal evidence.

Our analysis points out that while magnesium is particularly noted for its benefits, the details surrounding its standalone effectiveness in managing migraines remain unclear. It seems to work best when combined with lifestyle changes such as stress management and sleep hygiene, as well as with dietary adjustments that avoid common migraine triggers.

We understand that people looking for relief from migraines may find hope in using magnesium supplements. However, it's essential to highlight that in the broader context of migraine treatments, magnesium alone may not completely resolve the issue for everyone. So, while some individuals report improvements, it's not a one-size-fits-all solution.

References

  1. Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
  2. Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
  3. Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. doi:10.3389/fnut.2024.1433390
  4. Talandashti MK, Shahinfar H, Delgarm P, Jazayeri S. Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials. Neurol Sci. 2025;46:651. doi:10.1007/s10072-024-07794-0
  5. Gazerani P, Papetti L, Dalkara T, Cook CL, Webster C, et al. The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis. Nutrients. 2024;16. doi:10.3390/nu16142222
  6. Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
  7. Kurhade PI, Kodape SM, Das A, Bansod PG. Synergistic action of sumatriptan delivery and targeting magnesium deficiency using green, pH-responsive MgO nanoparticles synthesized from mahua flower extracts. Environ Sci Pollut Res Int. 2023. doi:10.1007/s11356-023-30648-9
  8. Umemoto KK, Tawk K, Mazhari N, Abouzari M, Djalilian HR. Management of Migraine-Associated Vestibulocochlear Disorders. Audiol Res. 2023;13:528. doi:10.3390/audiolres13040047
  9. Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
  10. Shenoy NN, Gheewala GK, Kedambadi R, Pai S, Zulfikli KM, et al. Can Serum Magnesium Level and Visual Evoked Potentials (P100) be a Predictive in Migraineurs?: Evidence Based Study. Neurol India. 2023;71:463. doi:10.4103/0028-3886.378668
  11. Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
  12. Pawar V, Ashraf H, Dorsala S, Mary P, Hameed N, et al. Motorist's Vestibular Disorientation Syndrome (MVDS)-Proposed Diagnostic Criteria. J Pers Med. 2023;13. doi:10.3390/jpm13050732
  13. Hoshino MT, Bochio MG, Spagnol Bonache J, Ludwig L, Leandro de Campos M, et al. Plasma and erythrocyte magnesium levels: from validation of the method to analysis in volunteers diagnosed to migraine. Magnes Res. 2022;35:51. doi:10.1684/mrh.2022.0502
  14. Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
  15. Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
  16. Mazza GR, Solorio C, Stek AM, Kalayjian LA, Wilson ML, et al. Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy. Arch Gynecol Obstet. 2023;308:1749. doi:10.1007/s00404-022-06872-y
  17. Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. doi:10.1007/s11916-022-01019-9
  18. Guerrero-Toro C, Koroleva K, Ermakova E, Gafurov O, Abushik P, et al. Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain. Int J Mol Sci. 2022;23. doi:10.3390/ijms23031529
  19. Matin H, Taghian F, Chitsaz A. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial. Neurol Sci. 2022;43:4413. doi:10.1007/s10072-021-05843-6
  20. Karim MR, Bhattacharjee M, Islam MS, Banerjee S, Hossain S, et al. Relation between Serum Magnesium Level and Migraine. Mymensingh Med J. 2021;30:301.
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