In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
Most Useful Reviews
9.5
Effective flu prevention
These small zinc tablets are taken daily during the COVID-19 pandemic to protect against flu and other infections. They effectively help avoid the common cold and flu. I find them better than Echinacea. When travelling during flu season, they are particularly useful for protection.
Read More
9.5
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
Read More
9.5
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.8
All Reviews
Positive Reviews
Negative Reviews
9.5
Effective flu prevention
These small zinc tablets are taken daily during the COVID-19 pandemic to protect against flu and other infections. They effectively help avoid the common cold and flu. I find them better than Echinacea. When travelling during flu season, they are particularly useful for protection.
Read More
9.5
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
Read More
9.5
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
Read More
8.8
Vital to recovery
When flu season arrives, this is always a must-have for keeping healthy or bouncing back.
Read More
9.5
Immune health support
Nature Made Zinc is a quality supplement providing essential support for immune health. I've been taking it for a few weeks and noticed a significant improvement; I haven't fallen ill since starting this supplement, which has been a relief during the cold and flu season. The capsules are easy to swallow with no strong taste. I trust Nature Made for its quality ingredients, which gives me confidence in this product's effectiveness. Being free from artificial colours, flavours, and preservatives makes this a natural choice for maintaining health. I highly recommend Nature Made Zinc to anyone wanting to strengthen their immune system and stay healthy throughout the year.
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential benefits in managing cold and flu symptoms, and there is some evidence to suggest that it may help reduce the severity and duration of these illnesses. Several clinical studies have indicated that zinc supplements can shorten the duration of cold symptoms if taken within the first 24 hours of their onset. While zinc may not necessarily prevent you from getting the flu, it could aid in alleviating symptoms and supporting your immune system during illness.
It's important to consider the appropriate dosage and consult with a healthcare provider before starting any supplementation, as excessive zinc intake can lead to adverse effects. Zinc lozenges and supplements can be helpful, but they should be part of a broader approach to flu prevention that includes vaccinations, maintaining a healthy lifestyle, and good hygiene practices. If you experience flu symptoms, it's always a good idea to consult a healthcare professional for tailored advice and treatment options.
Based on user reviews, many individuals report seeing results from taking the supplement within a few weeks. For example, one user noted a significant improvement in their immune health after taking Nature Made Zinc for just a few weeks, stating they hadn't fallen ill since starting the supplement, which was particularly reassuring during the cold and flu season (Read Review). Another user mentioned that taking the supplement seemed to help them recover quickly during flu and cold symptoms, indicating effectiveness when taken during active illness (Read Review).
Recent research highlights the potential benefits of zinc in combating flu symptoms and enhancing overall immune support. A study found that gargling with a mouthwash containing zinc resulted in a 21.5% reduction in the frequency and an 11% decrease in the severity of upper respiratory symptoms among participants. However, this study did not isolate the specific contributions of zinc alone, leaving some room for uncertainty regarding its efficacy in flu treatment [1]. Another investigation revealed that zinc plays a crucial role in lowering the expression of Cav1.2, a key receptor for influenza virus entry into cells, suggesting that zinc's indirect effects could be beneficial for preventing flu infections [2].
Moreover, the combination of zinc with herbal compounds demonstrated significant promise in reducing viral loads of respiratory RNA viruses, including influenza. This combination therapy showed a remarkable 50-95% reduction in viral genome replication across various strains [3]. Additionally, zinc's presence in Euglena extract was noted to inhibit various strains of the flu virus, indicating its role in enhancing the body’s defenses against the infection [4]. Overall, while more research is needed to fully understand the extent of zinc's benefits against the flu, current findings suggest that it could be a valuable component in flu prevention and treatment strategies [5].
Based on user reviews, many individuals have reported notable improvements in their symptoms after taking Nature Made Zinc. Several users indicated that the supplement has been effective in boosting their immune response, with one reviewer specifically mentioning that they hadn't fallen ill since starting the supplement, particularly during cold and flu season (Read Review). Another user emphasized that it has proven effective for acute respiratory infections and overall immune support, making it a staple in their household (Read Review).
In addition to immune health, some users have reported benefits for skin and hair, along with maintaining healthy testosterone levels, underscoring the multifunctional advantages of the supplement (Read Review). Others shared experiences of quicker recovery from flu symptoms and general effectiveness during illness, making Nature Made Zinc a go-to remedy when cold symptoms arise (Read Review). However, results can vary from person to person, so individual experiences may differ significantly.
Users have shared positive experiences regarding the combination of Nature Made Zinc with other supplements for managing flu symptoms. Several reviewers have pointed out that the supplement effectively supports their immune system, making it a valuable part of their health regimen, especially during flu season. One user noted that taking Nature Made Zinc helped them recover from flu symptoms more quickly, emphasizing its efficacy when taken during illness (Read Review). Another user corroborated this by describing it as an essential remedy for colds and flu, recommending it as a necessary addition to any first aid kit (Read Review).
Moreover, some users have indicated that they maintain a steady supply of Nature Made Zinc alongside other remedies to enhance their overall immune response when viruses are circulating. For instance, one reviewer mentioned that it is particularly effective against flu and acute respiratory infections, complementing their immune system efforts (Read Review). Overall, combining this supplement with a comprehensive health strategy appears advantageous to users seeking to fend off flu symptoms.
Based on user reviews, there appears to be a consensus on the effectiveness of Zinc for treating flu and supporting the immune system. Reviewers frequently mention that a dosage of 30mg is both effective and manageable, with comments highlighting that this specific dosage aids in quick recovery during flu and cold episodes (Read Review). Many users expressed their satisfaction, stating that they felt significant improvements in their health after incorporating Zinc into their daily regimen, attributing their unwellness avoidance during flu season to this supplement (Read Review).
Additionally, several users suggested taking Zinc as a preventive measure and as a remedy when flu symptoms arise, emphasizing that it serves as an essential component of their health routine (Read Review). Overall, customer feedback underscores Zinc's role in bolstering immune defenses, with users recommending it as a staple in home health supplies for its efficacy against infections (Read Review).
9.5
Immune health support
Nature Made Zinc is a quality supplement providing essential support for immune health. I've been taking it for a few weeks and noticed a significant improvement; I haven't fallen ill since starting this supplement, which has been a relief during the cold and flu season. The capsules are easy to swallow with no strong taste. I trust Nature Made for its quality ingredients, which gives me confidence in this product's effectiveness. Being free from artificial colours, flavours, and preservatives makes this a natural choice for maintaining health. I highly recommend Nature Made Zinc to anyone wanting to strengthen their immune system and stay healthy throughout the year.
8.8
Quick recovery aid
Good working zinc, with a 30mg dosage in one small tablet, taken during flu and colds, helps me recover quickly.
9.5
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
9.5
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
8.8
Must-have remedy
An excellent remedy for colds and flu, it's a must-have in your first aid kit. I advise taking it as a course.
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9
Zinc and flavonoids combat flu
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
References
Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. doi:10.1371/journal.pone.0316807
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. doi:10.3390/nu13113911
Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. doi:10.1007/s12011-021-02859-z