Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Zinc (as Zinc Gluconate)
30 mg
273%

Top Medical Research Studies

8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

Most Useful Reviews

9
Effective flu prevention
1 people found this helpful
These small zinc tablets are taken daily during the COVID-19 pandemic to protect against flu and other infections. They effectively help avoid the common cold and flu. I find them better than Echinacea. When travelling during flu season, they are particularly useful for protection.
Read More
9
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
Read More
9
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
  • All Researches
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective flu prevention
1 people found this helpful
These small zinc tablets are taken daily during the COVID-19 pandemic to protect against flu and other infections. They effectively help avoid the common cold and flu. I find them better than Echinacea. When travelling during flu season, they are particularly useful for protection.
Read More
9
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
Read More
9
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
Read More
7.5
Vital to recovery
1 people found this helpful
When flu season arrives, this is always a must-have for keeping healthy or bouncing back.
Read More
9
Immune health support
Nature Made Zinc is a quality supplement providing essential support for immune health. I've been taking it for a few weeks and noticed a significant improvement; I haven't fallen ill since starting this supplement, which has been a relief during the cold and flu season. The capsules are easy to swallow with no strong taste. I trust Nature Made for its quality ingredients, which gives me confidence in this product's effectiveness. Being free from artificial colours, flavours, and preservatives makes this a natural choice for maintaining health. I highly recommend Nature Made Zinc to anyone wanting to strengthen their immune system and stay healthy throughout the year.
Read More

Frequently Asked Questions

9
Immune health support
Nature Made Zinc is a quality supplement providing essential support for immune health. I've been taking it for a few weeks and noticed a significant improvement; I haven't fallen ill since starting this supplement, which has been a relief during the cold and flu season. The capsules are easy to swallow with no strong taste. I trust Nature Made for its quality ingredients, which gives me confidence in this product's effectiveness. Being free from artificial colours, flavours, and preservatives makes this a natural choice for maintaining health. I highly recommend Nature Made Zinc to anyone wanting to strengthen their immune system and stay healthy throughout the year.
7.5
Quick recovery aid
Good working zinc, with a 30mg dosage in one small tablet, taken during flu and colds, helps me recover quickly.
9
Effective for flu
The shape is good, and the dosage is also great. I always keep it at home as it is effective for flu, acute respiratory infections, and viral infections, helping to complete my immune system.
9
Reliable immune support
I have been taking Nature Made Zinc for several months and I am very pleased with the results. This product helps support my immune system and combat colds and flu. Additionally, it benefits skin and hair health as well as maintaining healthy testosterone levels. The tablets are easy to swallow with no unpleasant odour or taste. I recommend Nature Made Zinc for anyone seeking a dependable and effective health supplement.
7.5
Must-have remedy
An excellent remedy for colds and flu, it's a must-have in your first aid kit. I advise taking it as a course.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.

References

  1. Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. 10.1371/journal.pone.0316807
  2. Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. 10.21873/invivo.12967
  3. Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. 10.3390/ph15030377
  4. Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. 10.3390/nu13113911
  5. Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. 10.1007/s12011-021-02859-z
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