5/30/2025
Last update
5/30/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
USERS' SCORE
Good
Based on 25 Reviews
8.6
Supplement Facts
Serving Size: 3 Caplets
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
15 mcg (600 IU)
75%
Calcium (as Calcium Carbonate and Calcium Gluconate)
1,000 mg
77%
Magnesium (as Magnesium Oxide and Magnesium Gluconate)
400 mg
95%
Zinc (as Zinc Gluconate and Zinc Citrate)
25 mg
227%
Sodium
10 mg
<1%
Top Medical Research Studies
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
8
Vitamin D benefits for insomnia
We set out to explore the relationship between vitamin D and insomnia by examining how low-fat milk and yogurt fortified with 1,500 IU of nano-encapsulated vitamin D could improve sleep issues and overall quality of life.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
Read More
8
We explored the effects of zinc on sleep by looking at how it might help with insomnia. In our study, we gave mice a zinc-containing yeast extract and monitored their behavior and brain activity. The results were quite promising.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
We found that administering zinc at doses of 40 and 80 mg/kg led to a significant increase in non-rapid eye movement (NREM) sleep. This means that the mice were not only sleeping longer but also showed less activity, which is a good indicator of effective sleep. Interestingly, we did not observe any changes in rapid eye movement (REM) sleep, a crucial sleep phase for dreaming and deep rest.
Importantly, we didn’t see any negative side effects, such as rebound insomnia, within 24 hours after treating the mice. This suggests that zinc could be a safe option for those struggling with sleep issues, unlike other mineral extracts we tested, such as manganese, iron, and copper, which did not affect locomotor activity at all.
Overall, our findings provide the first evidence that zinc has a direct role in promoting sleep, opening up exciting possibilities for new sleep supplements featuring this essential mineral.
Read More
Most Useful Reviews
9
Insomnia disappeared
102 people found this helpful
An excellent and effective remedy for men, I found my sleep improved after just a week, and my insomnia disappeared. Mornings have become more pleasant, and my wife has noticed the difference too. I recommend these vitamins to all men seeking to enhance their overall health.
Read More
9
Sleep returned normal
7 people found this helpful
Saying goodbye to nervousness and insomnia has been liberating. My job is stressful, and after a month of taking these vitamins, I have seen significant improvement. My sleep has normalised, my nerves are steadier, and I even have the energy for household chores and lessons with the children. I've also noticed clearer skin and stronger hair and nails. I take one tablet in the afternoon, closer to bedtime. Highly recommend these vitamins at a reasonable price.
Read More
10
Insomnia no more
This is my favourite. It calms me well and improves my sleep. I’ve forgotten what insomnia is.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
- All Researches
9
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
We explored the case of an emmetropic woman experiencing excessive daytime sleepiness alongside insomnia, which aligned with the criteria for a non-24 h sleep-wake disorder. After traditional treatments failed, we discovered deficiencies in vitamin B12, vitamin D3, and folic acid.
Upon supplementing these nutrients, we observed a restoration of a 24-hour sleep-wake rhythm in the participant. Interestingly, this improvement occurred independently of the natural light-dark cycle, raising questions about the specific impact of vitamin D on sleep patterns.
While our study underscores how addressing vitamin deficiencies can influence sleep, it also leaves us pondering whether vitamin D plays a direct role as an essential factor or if it merely acts as a concurrent indicator of overall health.
Upon supplementing these nutrients, we observed a restoration of a 24-hour sleep-wake rhythm in the participant. Interestingly, this improvement occurred independently of the natural light-dark cycle, raising questions about the specific impact of vitamin D on sleep patterns.
While our study underscores how addressing vitamin deficiencies can influence sleep, it also leaves us pondering whether vitamin D plays a direct role as an essential factor or if it merely acts as a concurrent indicator of overall health.
Read More
8
Vitamin D benefits for insomnia
We set out to explore the relationship between vitamin D and insomnia by examining how low-fat milk and yogurt fortified with 1,500 IU of nano-encapsulated vitamin D could improve sleep issues and overall quality of life.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
Read More
User Reviews
USERS' SCORE
Good
Based on 25 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Insomnia disappeared
102 people found this helpful
An excellent and effective remedy for men, I found my sleep improved after just a week, and my insomnia disappeared. Mornings have become more pleasant, and my wife has noticed the difference too. I recommend these vitamins to all men seeking to enhance their overall health.
Read More
9
Sleep returned normal
7 people found this helpful
Saying goodbye to nervousness and insomnia has been liberating. My job is stressful, and after a month of taking these vitamins, I have seen significant improvement. My sleep has normalised, my nerves are steadier, and I even have the energy for household chores and lessons with the children. I've also noticed clearer skin and stronger hair and nails. I take one tablet in the afternoon, closer to bedtime. Highly recommend these vitamins at a reasonable price.
Read More
10
Insomnia no more
This is my favourite. It calms me well and improves my sleep. I’ve forgotten what insomnia is.
Read More
9
Improved anxiety feelings
Remarkably effective! I bought this for my mother for preventive reasons. By the second day, she noticed a change; her sleep improved, reducing her anxiety and insomnia. I was so impressed that I ordered another bottle immediately. I also supplement with D3, as the daily dose here is insufficient. I appreciate any useful feedback; here’s to good health!
Read More
9
Enhanced sleep quality
I suffered from insomnia following my operation, but after nearly three months of taking this product, my sleep quality has genuinely improved. It also addresses nutrient deficiencies, and while the taste is neutral, it can be cut in half for easier swallowing. I plan on continuing with this.
Read More
Frequently Asked Questions
9
Insomnia disappeared
102 people found this helpful
An excellent and effective remedy for men, I found my sleep improved after just a week, and my insomnia disappeared. Mornings have become more pleasant, and my wife has noticed the difference too. I recommend these vitamins to all men seeking to enhance their overall health.
7.5
Better sleep noticed
After taking these for ten days, I noticed the effect was cumulative. I have been struggling with insomnia and constant stress, but my sleep has improved significantly. I take one tablet in the evening, and they are sizeable yet manageable to swallow. The packaging is secure, instilling confidence. I highly advise trying them.
9
Enhanced sleep quality
I suffered from insomnia following my operation, but after nearly three months of taking this product, my sleep quality has genuinely improved. It also addresses nutrient deficiencies, and while the taste is neutral, it can be cut in half for easier swallowing. I plan on continuing with this.
9
Sleep returned normal
7 people found this helpful
Saying goodbye to nervousness and insomnia has been liberating. My job is stressful, and after a month of taking these vitamins, I have seen significant improvement. My sleep has normalised, my nerves are steadier, and I even have the energy for household chores and lessons with the children. I've also noticed clearer skin and stronger hair and nails. I take one tablet in the afternoon, closer to bedtime. Highly recommend these vitamins at a reasonable price.
7.5
Reduced anxiety symptoms
Absolutely fantastic for alleviating symptoms like insomnia and anxiety.
9
Magnesium helps insomnia
Good composition. Insomnia disappeared, likely due to the presence of magnesium. Additionally, calf muscle spasms have become less of a concern.
9
Improved anxiety feelings
Remarkably effective! I bought this for my mother for preventive reasons. By the second day, she noticed a change; her sleep improved, reducing her anxiety and insomnia. I was so impressed that I ordered another bottle immediately. I also supplement with D3, as the daily dose here is insufficient. I appreciate any useful feedback; here’s to good health!
7.5
Convenient solution
All necessary nutrients are in one capsule, which is very convenient. I can't speak for tests, but magnesium at bedtime benefits everyone. It has significantly helped my insomnia. The taste is pleasant, and I've noticed improvements in my condition.
9
Cheerful and rejuvenated
After two months of use, I've noticed my hair is growing faster, insomnia has vanished, and I'm generally more cheerful. I recommend it!
9
Reduced insomnia symptoms
Wonderful! I ordered this vitamin for both myself and my husband. He suffered from insomnia, but now he sleeps well every night. It contains a substantial amount of calcium, magnesium, and zinc. My calcium deficiency has improved, and I'm ordering another bottle for myself and my mother, who has osteoporosis. Thank you.
9
Good sleep at night
I take two capsules in the evening. I sleep well, and they help with my insomnia, but I will take breaks between jars.
7.5
Improved sleep quality
2 people found this helpful
It greatly assists in managing insomnia. If taken before bedtime, you can expect restful sleep.
7
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Vitamin D benefits for insomnia
We set out to explore the relationship between vitamin D and insomnia by examining how low-fat milk and yogurt fortified with 1,500 IU of nano-encapsulated vitamin D could improve sleep issues and overall quality of life.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
In our analysis, we included adults with abdominal obesity and a history of insomnia, identifying twenty-nine participants through insomnia severity questionnaires. They were split into four groups: one receiving fortified low-fat milk, another with unfortified milk, a third group consuming fortified yogurt, and a fourth with unfortified yogurt. Over a ten-week period, we tracked changes in insomnia symptoms and quality of life.
Our findings revealed that those drinking the vitamin D fortified milk experienced significant improvements in insomnia scores compared to those consuming regular milk. Additionally, quality of life assessments showed positive changes for both fortified and unfortified milk groups. However, the yogurt groups did not demonstrate significant benefits, indicating that while fortified dairy has potential, yogurt may not be as effective in this context.
In conclusion, incorporating fortified low-fat milk into our diets could help ease insomnia symptoms and enhance life satisfaction, although yogurt did not show the same promise.
8
We explored the case of an emmetropic woman experiencing excessive daytime sleepiness alongside insomnia, which aligned with the criteria for a non-24 h sleep-wake disorder. After traditional treatments failed, we discovered deficiencies in vitamin B12, vitamin D3, and folic acid.
Upon supplementing these nutrients, we observed a restoration of a 24-hour sleep-wake rhythm in the participant. Interestingly, this improvement occurred independently of the natural light-dark cycle, raising questions about the specific impact of vitamin D on sleep patterns.
While our study underscores how addressing vitamin deficiencies can influence sleep, it also leaves us pondering whether vitamin D plays a direct role as an essential factor or if it merely acts as a concurrent indicator of overall health.
Upon supplementing these nutrients, we observed a restoration of a 24-hour sleep-wake rhythm in the participant. Interestingly, this improvement occurred independently of the natural light-dark cycle, raising questions about the specific impact of vitamin D on sleep patterns.
While our study underscores how addressing vitamin deficiencies can influence sleep, it also leaves us pondering whether vitamin D plays a direct role as an essential factor or if it merely acts as a concurrent indicator of overall health.
References
- Radlberger RF, Kunz AB. Vitamin D deficiency promoting non-24 h sleep-wake disorder: a case report. Front Neurol. 2023;14:1141835. 10.3389/fneur.2023.1141835
- Sharifan P, Khoshakhlagh M, Khorasanchi Z, Darroudi S, Rezaie M, et al. Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial. Food Sci Nutr. 2020;8:4484. 10.1002/fsn3.1750
- Zhang HJ, Zhang JR, Mao CJ, Li K, Wang F, et al. Relationship between 25-Hydroxyvitamin D, bone density, and Parkinson's disease symptoms. Acta Neurol Scand. 2019;140:274. 10.1111/ane.13141
- Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. 10.3389/fendo.2024.1370733
- Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. 10.1186/s12871-024-02579-6
- Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. 10.7759/cureus.59317
- Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. 10.1186/s12906-021-03297-z
- Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. 10.3889/oamjms.2019.771
- Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. 10.3390/nu10101354
- Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. 10.3390/nu9020154
- Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
- Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. 10.1111/j.1532-5415.2010.03232.x
- Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
- Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
- Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.
- Cappelli V, Morgante G, Di Sabatino A, Massaro MG, De Leo V. [Evaluation of the efficacy of a new nutraceutical product in the treatment of postmenopausal symptoms]. Minerva Ginecol. 2015;67:515.
- Cherasse Y, Saito H, Nagata N, Aritake K, Lazarus M, et al. Zinc-containing yeast extract promotes nonrapid eye movement sleep in mice. Mol Nutr Food Res. 2015;59:2087. 10.1002/mnfr.201500082
