Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Magnesium (as Magnesium Oxide)
500 mg
119%

Top Medical Research Studies

We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.

Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.

Overall, our findings support its potential use in heart treatments.
9
Magnesium nanoparticles enhance clotting time
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
8
Magnesium scaffolds lower clotting risks
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.

Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.

This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.

Most Useful Reviews

9
Needed magnesium
3 people found this helpful
Excellent product! I have a medical requirement for magnesium, which Nature's Bounty has successfully met. My blood work has improved significantly, moving from 'red' to 'green'. Although I take 2500 mg daily, I trust this product more than others claiming to provide higher dosages.
7.5
Reduced irritability
34 people found this helpful
It helped a lot when my grandmother's blood pressure spiked. She was very irritable and had trouble sleeping, but the effect became noticeable after a week. I recommend it.
7.5
Calms nerves effectively
21 people found this helpful
Magnesium aids in relaxing muscle fibres and acts as a natural anti-stress factor. It inhibits excitement in the central nervous system, helping me feel calmer. I recommend it!

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
  • All Researches
9
Magnesium nanoparticles enhance clotting time
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
8
Magnesium intake reduces RVO risk
We explored whether magnesium intake could influence the risk of retinal vein occlusion (RVO), a leading cause of vision loss. Our analysis involved over 16,000 participants from a national health survey.

We discovered that sufficient magnesium intake was linked to a significant 64% reduced risk of RVO.

This finding was especially relevant for adults under 60, those with hypertension, and individuals without glaucoma. Further studies are needed to confirm magnesium's preventive benefits for RVO.
8
Effective clay-based hemostatic sponge
We examined a new sponge made from clay and collagen to control severe bleeding. Integrating palygorskite clay with collagen using gallic acid created a sponge that resists particle shedding and provides strong adhesion.

In our tests, this sponge demonstrated impressive results, reducing blood loss to 632 mg and achieving hemostasis in just 151 seconds, outperforming traditional gauze and even a well-known product called QuikClot.

With added antibacterial and antioxidant properties, this sponge could significantly enhance emergency bleeding management.
8
Magnesium scaffolds lower clotting risks
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.

Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.

This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
8
Bioresorbable stents' advancements noted
We explored the evolution of bioresorbable metallic stents as alternatives to traditional stents which can lead to complications like thrombosis and inflammation.

While bioresorbable polymeric stents face challenges, materials like zinc and magnesium show promise.

Specifically, magnesium-based stents have demonstrated successful absorption within a year and low rates of complications.

Continuing research will be essential to refine these innovations for better clinical outcomes.

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Needed magnesium
3 people found this helpful
Excellent product! I have a medical requirement for magnesium, which Nature's Bounty has successfully met. My blood work has improved significantly, moving from 'red' to 'green'. Although I take 2500 mg daily, I trust this product more than others claiming to provide higher dosages.
7.5
Reduced irritability
34 people found this helpful
It helped a lot when my grandmother's blood pressure spiked. She was very irritable and had trouble sleeping, but the effect became noticeable after a week. I recommend it.
7.5
Calms nerves effectively
21 people found this helpful
Magnesium aids in relaxing muscle fibres and acts as a natural anti-stress factor. It inhibits excitement in the central nervous system, helping me feel calmer. I recommend it!
7.5
Enhances circulation
Excellent! A good price for this high dosage. The quality is superb and it improves blood circulation, which is very beneficial for treating the nervous system.
6
Effective supplement
Good! Used as a dietary supplement, my blood tests indicate that it is likely doing its job effectively.

Frequently Asked Questions

7.5
Reduced irritability
34 people found this helpful
It helped a lot when my grandmother's blood pressure spiked. She was very irritable and had trouble sleeping, but the effect became noticeable after a week. I recommend it.
9
Needed magnesium
3 people found this helpful
Excellent product! I have a medical requirement for magnesium, which Nature's Bounty has successfully met. My blood work has improved significantly, moving from 'red' to 'green'. Although I take 2500 mg daily, I trust this product more than others claiming to provide higher dosages.
6
Effective supplement
Good! Used as a dietary supplement, my blood tests indicate that it is likely doing its job effectively.
7.5
Calms nerves effectively
21 people found this helpful
Magnesium aids in relaxing muscle fibres and acts as a natural anti-stress factor. It inhibits excitement in the central nervous system, helping me feel calmer. I recommend it!
7.5
Enhances circulation
Excellent! A good price for this high dosage. The quality is superb and it improves blood circulation, which is very beneficial for treating the nervous system.
We studied how a lack of magnesium transporter 1 (MAGT1) impacts blood clot formation and the risk of stroke. Using various laboratory and animal models, we observed that MAGT1 deficiency leads to enhanced platelet activity and quicker clotting. This deficiency resulted in faster artery blockage and severe brain damage during strokes. Interestingly, restoring magnesium levels or blocking certain channels helped normalize platelet behavior. Overall, we found that MAGT1's function is crucial for vascular health, indicating its deficiency could elevate risks for thrombosis and ischemic stroke.
8
Magnesium scaffolds lower clotting risks
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.

Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.

This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
8
Effective magnesium scaffold outcomes
We assessed the long-term safety and effectiveness of a resorbable magnesium scaffold in treating coronary artery disease through the BIOSOLVE-IV registry. This study involved over 2,000 patients from diverse regions, with assessments at 6, 12, and 24 months.

The results showed a 24-month target lesion failure rate of 6.8%, with scaffolding success rates impressively high at 97.5%. Notably, scaffold thrombosis occurred in 0.8% of patients. These findings suggest that magnesium scaffolds can be safely integrated into clinical practice, paving the way for future cardiac interventions.
9
Magnesium nanoparticles enhance clotting time
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.

References

  1. Kim J, Kim M, Lee CS, Choi EY. Sufficient Magnesium Intake Reduces Retinal Vein Occlusion Risk: National Health and Nutrition Examination Survey Analysis. Nutrients. 2025;17. doi:10.3390/nu17071285
  2. Guo X, Zeng X, He Y, Zhang X, Shi W, et al. An Antibacterial, Antioxidant Adherent Sponge Constructed for Control of Arterial Bleeding Via Gallic Acid-Mediated Robust Assembly of Fibrous Clay in Collagen. ACS Appl Mater Interfaces. 2025;17:16489. doi:10.1021/acsami.4c19209
  3. Müller M, Ludwig L, Englert H, Riedl KA, Müller MC, et al. A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds. Sci Rep. 2024;14:26691. doi:10.1038/s41598-024-77266-0
  4. Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
  5. Włodarczak A, Rola P, Włodarczak S, Szudrowicz M, Giniewicz K, et al. Two-Year Outcomes for Patients with Non-ST-Elevation Acute Coronary Syndrome Treated with Magmaris and Absorb Bioresorbable Scaffolds in Large-Vessel Lesions. J Pers Med. 2024;14. doi:10.3390/jpm14050540
  6. Galli S, Troiano S, Palloshi A, Rapetto C, Pisano F, et al. Comparison of acute versus stable coronary syndrome in patients treated with the Magmaris scaffold: Two-year results from the Magmaris Multicenter Italian Registry. Cardiovasc Revasc Med. 2023;57:53. doi:10.1016/j.carrev.2023.06.022
  7. Włodarczak A, Rola P, Barycki M, Furtan Ł, Łanocha M, et al. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds - magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort. Diab Vasc Dis Res. 2023;20:14791641231188705. doi:10.1177/14791641231188705
  8. Gotru SK, Mammadova-Bach E, Sogkas G, Schuhmann MK, Schmitt K, et al. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Arterioscler Thromb Vasc Biol. 2023;43:1494. doi:10.1161/ATVBAHA.122.318115
  9. Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. EuroIntervention. 2023;19:e414. doi:10.4244/EIJ-D-23-00326
  10. Wlodarczak A, Montorsi P, Torzewski J, Bennett J, Starmer G, et al. One- and two-year clinical outcomes of treatment with resorbable magnesium scaffolds for coronary artery disease: the prospective, international, multicentre BIOSOLVE-IV registry. EuroIntervention. 2023;19:232. doi:10.4244/EIJ-D-22-01069
  11. Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. Safety and performance of the third-generation drug-eluting resorbable coronary magnesium scaffold system in the treatment of subjects with de novo coronary artery lesions: 6-month results of the prospective, multicenter BIOMAG-I first-in-human study. EClinicalMedicine. 2023;59:101940. doi:10.1016/j.eclinm.2023.101940
  12. Pompei G, Campo G, Ruggiero R, Maffeo D, Sgura F, et al. Long-term outcomes of patients treated with sirolimus-eluting resorbable magnesium scaffolds: Insights from the SHERPA-MAGIC study. Int J Cardiol. 2023;383:1. doi:10.1016/j.ijcard.2023.04.029
  13. Fedele G, Castiglioni S, Maier JAM, Locatelli L. The Effects of Sirolimus and Magnesium on Primary Human Coronary Endothelial Cells: An In Vitro Study. Int J Mol Sci. 2023;24. doi:10.3390/ijms24032930
  14. Tonai K, Katayama S, Koyama K, Sata N, Tomioka Y, et al. Association between hypomagnesemia and coagulopathy in sepsis: a retrospective observational study. BMC Anesthesiol. 2022;22:359. doi:10.1186/s12871-022-01903-2
  15. Seguchi M, Aytekin A, Lenz T, Nicol P, Alvarez-Covarrubias HA, et al. Challenges of the newer generation of resorbable magnesium scaffolds: Lessons from failure mechanisms of the past generation. J Cardiol. 2023;81:179. doi:10.1016/j.jjcc.2022.09.003
  16. Venkatappa MM, Udagani C, Hanumegowda SM, Pramod SN, Venkataramaiah S, et al. Effect of Biofunctional Green Synthesized MgO-Nanoparticles on Oxidative-Stress-Induced Tissue Damage and Thrombosis. Molecules. 2022;27. doi:10.3390/molecules27165162
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