Vitamin D and activity improve survivalVitamin D status, physical activity and long-term mortality risk after myocardial infarction: a prospective analysis in the Alpha Omega Cohort.
Relevant score indicates study impact
We examined how vitamin D status and physical activity (PA) relate to long-term survival following a heart attack, also known as a myocardial infarction (MI). In our analysis of 4,837 MI patients, we measured the levels of vitamin D in their blood and assessed their physical activity using a reliable questionnaire.
Over an average follow-up of 14.4 years, we observed that higher vitamin D levels were linked to a significant reduction in both cardiovascular (CVD) and all-cause mortality. Specifically, patients with adequate vitamin D levels had about 37% lower risk of CVD-related deaths compared to those with lower levels. Additionally, engaging in more physical activity also correlated with a lower mortality risk.
Importantly, we found that those with low vitamin D levels and little to no physical activity faced a threefold increased risk of mortality compared to patients who had high vitamin D levels and were active. These findings suggest that both vitamin D and physical activity independently contribute to improving survival rates post-heart attack, regardless of other health factors.
Overall, this study underscores the importance of monitoring vitamin D levels and encouraging physical activity to enhance recovery and longevity after a heart attack.
Read More
Vitamin D aids in heart attack recoveryEvaluating the therapeutic effect of vitamin D and nerolidol on lung injury due to experimental myocardial infarction: The potential role of asprosin and spexin.
Moderate relevance to vitamin D treatment
We conducted a study to understand how vitamin D could impact lung injuries resulting from a heart attack, specifically myocardial infarction. The research involved six groups of experimental animals to investigate different treatment approaches. Among these groups were those receiving only vitamin D, those treated with nerolidol, and those experiencing myocardial infarction without any treatment.
Our findings indicated that serious lung injuries indeed occurred due to myocardial infarction. Notably, treatments with vitamin D showed a potential curative effect on these injuries. We also explored the role of two proteins, asprosin and spexin, which appeared to be linked to both the damages and the recovery processes within the lungs.
Interestingly, it seemed that vitamin D's effectiveness depended on the expression of asprosin and spexin, while nerolidol could operate through a different mechanism that may not rely on these proteins. These insights into how vitamin D and nerolidol can mitigate the effects of heart attacks open avenues for further exploration in treatment.
Read More
Vitamin D reduces heart attack riskAssociations of serum 25-hydroxyvitamin D and vitamin D receptor polymorphisms with risks of cardiovascular disease and mortality among patients with chronic kidney disease: a prospective study.
Study shows strong vitamin D effects
We explored the relationship between vitamin D levels and heart attack risks among individuals with chronic kidney disease (CKD). In this comprehensive study involving over 21,500 participants, researchers examined how varying levels of serum 25-hydroxyvitamin D influenced the incidence of cardiovascular diseases (CVD) and overall mortality.
The findings are quite intriguing. Individuals with higher serum vitamin D concentrations, specifically those above 75 nmol/L, were found to have significantly lower risks of experiencing heart-related issues, including total cardiovascular incidents and strokes. For instance, the risk of heart attacks dropped notably for those with higher vitamin D levels.
Importantly, this beneficial association persisted regardless of genetic variations related to vitamin D receptors. This suggests that maintaining adequate vitamin D levels could play a vital role in reducing heart attack risks and improving survival rates for CKD patients. All in all, this study drives home the idea that proper vitamin D status is essential for cardiovascular health in the CKD population.
Read More
We aimed to explore how vitamin D, specifically serum 25-hydroxyvitamin D levels, might be associated with the risk of heart attacks and other cardiovascular events in individuals with pre-existing coronary heart disease. Our research included a substantial group of 22,571 participants from the UK Biobank, where we analyzed electronic health records to track incidents of myocardial infarction, heart failure, stroke, and cardiovascular-related mortality.
By utilizing advanced statistical methods, we were able to assess the relationship between vitamin D levels and recurrent cardiovascular events over a median follow-up of 11.2 years. Our findings revealed a notable trend: higher levels of serum 25(OH)D were linked to a reduced risk of experiencing heart attacks and other cardiovascular issues. Particularly, we noticed that the most significant benefits occurred when levels reached around 50 nmol/L, indicating this could be a crucial threshold for maintaining heart health.
Interestingly, the patterns we observed remained consistent regardless of various genetic factors related to the vitamin D receptor, suggesting that the positive effects of vitamin D on heart health are robust across different genetic backgrounds. Overall, this underscores the importance of maintaining adequate vitamin D levels for individuals with coronary heart disease, as it could play a vital role in preventing further cardiovascular complications.
Read More
We investigated the relationship between vitamin D levels and sleep quality in patients who recently suffered a myocardial infarction (heart attack). In a randomized controlled study, we included 34 patients with MI and compared their outcomes to 17 healthy controls. The patients were divided into two groups that received either blue or white light therapy during their stay in the intensive care unit.
Our findings revealed that patients with MI had significantly lower vitamin D levels compared to healthy individuals, suggesting that they might be at risk for deficiencies. Moreover, the MI group experienced poorer sleep quality, with higher sleep onset latency and fewer overall sleep efficiencies.
After light therapy, we noted a significant increase in vitamin D levels for the blue light group, indicating that light exposure may benefit both vitamin D status and potentially sleep quality. However, we didn't observe a significant difference in sleep measures after the therapy, apart from a trend suggesting better circadian rhythm in the blue light group.
These results point towards the importance of interventions that could improve sleep and vitamin D levels in heart attack patients, signaling a potential area for further research. While the improvements in vitamin D levels are promising, we acknowledge that the overall benefits on sleep and recovery remain inconclusive and require additional investigation.
Read More