Last update
5/16/2025

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Caplet
Amount Per Serving
%DV
Zinc (as Zinc Gluconate)
50 mg
455%

Top Medical Research Studies

9
Zinc insulin alleviates hives
We observed a fascinating case of a young woman with diabetes who experienced chronic hives after switching her insulin type. Initially, she moved from a standard isophane insulin to a beef-pork version, which then triggered her hives. Even after she returned to her original insulin, the hives continued to be a problem.

During her hospital stay, we noted that her hives reappeared daily after insulin injections. This situation changed when we introduced a purer form of insulin called zinc single-peak beef insulin suspension. Surprisingly, the urticaria cleared up quickly after this switch.

Through skin testing, we discovered her sensitivity was primarily to the beef and pork forms of the isophane insulin. However, she showed no sensitivity to the zinc insulin forms. Although she did experience a brief return of the hives after taking antibiotics, this time they did not reappear at the insulin injection sites.

This case provides valuable insight into how certain insulin components can lead to hives, and how switching to a zinc preparation offered the young woman some relief.
Read More

Most Useful Reviews

9
Overdose warning
4 people found this helpful
WARNING: 50mg might be too much! After taking my first 50mg pill while recovering from a cold, I suffered an allergic reaction that resulted in hives all over my body, necessitating a trip to the ER. I believe the dosage should be reduced to 20-30mg. Despite my mistake, I gave a good review, as the reaction was my fault, not the product's. I'm advised to try cutting the pill in half to avoid similar issues in the future.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
9
Zinc insulin alleviates hives
We observed a fascinating case of a young woman with diabetes who experienced chronic hives after switching her insulin type. Initially, she moved from a standard isophane insulin to a beef-pork version, which then triggered her hives. Even after she returned to her original insulin, the hives continued to be a problem.

During her hospital stay, we noted that her hives reappeared daily after insulin injections. This situation changed when we introduced a purer form of insulin called zinc single-peak beef insulin suspension. Surprisingly, the urticaria cleared up quickly after this switch.

Through skin testing, we discovered her sensitivity was primarily to the beef and pork forms of the isophane insulin. However, she showed no sensitivity to the zinc insulin forms. Although she did experience a brief return of the hives after taking antibiotics, this time they did not reappear at the insulin injection sites.

This case provides valuable insight into how certain insulin components can lead to hives, and how switching to a zinc preparation offered the young woman some relief.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Overdose warning
4 people found this helpful
WARNING: 50mg might be too much! After taking my first 50mg pill while recovering from a cold, I suffered an allergic reaction that resulted in hives all over my body, necessitating a trip to the ER. I believe the dosage should be reduced to 20-30mg. Despite my mistake, I gave a good review, as the reaction was my fault, not the product's. I'm advised to try cutting the pill in half to avoid similar issues in the future.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Shore RN, Shelley WB, Kyle GC. Chronic urticaria from isophane insulin therapy; sensitivity associated with noninsulin components in commercial preparations. Arch Dermatol. 1975;111:94.
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