We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
Most Useful Reviews
9
Cough prevention
4 people found this helpful
I drink zinc periodically since last year, and this one is much better than those from pharmacies. Remember, do not increase your dosage. After taking this zinc, I’ve completely forgotten about coughing. It really works without any doubt.
Read More
9
Cough relief
2 people found this helpful
I liked it! An essential vitamin for maintaining immunity. My husband and I take it periodically, especially during the coronavirus and cold season. I even give it to my daughter when she begins coughing, and it helps prevent the cough from worsening! I recommend it!
Read More
10
Chronic cough help
Very effective for coughing, particularly for those with chronic bronchitis. This zinc did not cause any allergies, unlike some Russian drugs I tried.
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.7
All Reviews
Positive Reviews
Negative Reviews
9
Cough prevention
4 people found this helpful
I drink zinc periodically since last year, and this one is much better than those from pharmacies. Remember, do not increase your dosage. After taking this zinc, I’ve completely forgotten about coughing. It really works without any doubt.
Read More
9
Cough relief
2 people found this helpful
I liked it! An essential vitamin for maintaining immunity. My husband and I take it periodically, especially during the coronavirus and cold season. I even give it to my daughter when she begins coughing, and it helps prevent the cough from worsening! I recommend it!
Read More
10
Chronic cough help
Very effective for coughing, particularly for those with chronic bronchitis. This zinc did not cause any allergies, unlike some Russian drugs I tried.
Read More
10
Quick cough relief
I bought these lozenges due to their high potency for coronavirus protection. One night, I had a persistent cough, but after taking a lozenge, the cough disappeared within seconds! The next morning, I experienced taste loss, which worried me, but I remembered that the lozenges can cause this temporary effect.
Read More
10
Rapid cough cure
I began giving my husband one lozenge in the morning after eating when he started coughing; after three days, the cough was gone!
Coughing is a reflex action that helps clear the airways of mucus, irritants, or foreign particles. It is a natural mechanism the body uses to protect itself and can be triggered by various factors, including infections, allergies, or environmental irritants. There are two main types of coughs: acute coughs, which typically last less than three weeks and often result from a cold or respiratory infection, and chronic coughs, which persist for more than eight weeks and may indicate a more serious underlying condition.
Coughs can also be classified as dry or productive. A dry cough does not produce mucus, while a productive cough does. Treatment options depend on the underlying cause; over-the-counter medications, home remedies, or medical intervention may be recommended based on the severity and duration of the cough. If a cough is persistent, accompanied by other symptoms like fever, shortness of breath, or chest pain, it’s advisable to seek medical advice for a proper diagnosis and treatment plan.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has garnered attention for its potential role in reducing the duration and severity of colds, which often include symptoms like cough. Some studies suggest that zinc may help by modulating the immune response and reducing inflammation in the throat and respiratory tract. While there are mixed results regarding its efficacy specifically for cough relief, it is commonly found in over-the-counter cold remedies. It’s important to note that more research is needed to confirm these benefits conclusively.
Based on user reviews, the timeframe to experience relief from coughing when taking this zinc supplement can vary. Several users report seeing results within just a few days. For instance, one user stated that after giving their husband a lozenge for three days, the cough was gone completely Read Review. Another user indicated that after they took a lozenge for a persistent cough, it disappeared within seconds Read Review.
Many users suggest that starting the supplement as soon as cough symptoms appear can lead to faster recovery, often noticing improvements within 24 to 72 hours. For example, one user mentioned that using the supplement helped alleviate early cold symptoms overnight, which included a cough Read Review. Overall, while individual experiences may vary, multiple reports highlight that within a few days of consistent use, users found significant relief from coughing and related symptoms.
The use of zinc as a supplement for cough relief has shown mixed results in scientific research. In a pilot study specifically investigating zinc acetate for chronic refractory cough, participants did experience an increase in serum zinc levels, but the overall improvements in cough symptoms and quality of life were minimal and did not reach clinically meaningful thresholds. The study ultimately concluded that zinc therapy does not provide substantial advantage over placebo for individuals suffering from chronic cough, suggesting that further large-scale trials may be unnecessary at this time [1].
Conversely, zinc has been explored in other contexts, such as in Epipharyngeal Abrasive Therapy (EAT) for chronic cough linked to Long COVID. While EAT shows promise in reducing inflammation and aiding recovery, the impact of zinc specifically is difficult to isolate due to the combination of treatments involved [2]. Additionally, a study combining zinc with other micronutrients and medications found notable improvements in cough symptoms among COVID-19 patients, but again, it doesn't specify zinc's isolated effect [3]. Overall, while zinc may contribute to cough management in certain scenarios, existing studies do not currently support its use as a standalone treatment.
Based on user reviews, many individuals have reported significant improvements in their cough symptoms after using this zinc supplement. For instance, one user shared that after taking the zinc, they completely forgot about their coughing, highlighting a clear positive impact on their symptoms Read Review. Another user noted that the zinc was particularly effective for individuals with chronic bronchitis, underscoring its utility for those with persistent coughing issues Read Review.
Moreover, several users assert that the supplement not only addresses cough symptoms effectively but also helps in preventing cough severity, especially when taken at the onset of symptoms. For example, one user indicated that their daughter's cough improved significantly upon early administration Read Review. A report of a user experiencing a rapid reduction of a persistent cough within seconds of taking a lozenge further illustrates the efficacy of this supplement Read Review. Overall, while results can vary from person to person, many users have reported swift and effective relief from their coughs with this zinc product.
Based on user reviews, many individuals reported positive experiences when combining this zinc supplement with other nutritional routines for managing coughs. Users frequently noted that they incorporate zinc into their regimen, especially during cold and flu season, highlighting its role in preventing coughs from worsening. One parent mentioned giving zinc to their daughter during the onset of cough symptoms, which helped in preventing further complications and highlighted its preventive benefits Read Review. Another user emphasized the supplement's effectiveness for those with chronic conditions, such as bronchitis, indicating that it can be particularly beneficial when used alongside other health measures Read Review.
Additionally, users reported that taking the zinc lozenges during times of persistent coughing led to almost immediate relief, often pairing it with other supportive measures like rest and hydration. One customer noted that a lozenge taken at the onset of a persistent cough led to rapid relief within seconds, showcasing the quick acting nature of zinc in conjunction with their other treatments Read Review. Many users seem to find that consistent use of this supplement, especially during early symptoms, contributes to better overall respiratory health and supports immune function alongside other wellness practices.
Users report varying experiences regarding the appropriate dosage of zinc for treating cough, emphasizing the importance of not exceeding recommended amounts. For instance, one user highlighted that they experienced significant relief from coughing after taking the correct dose, stating, "remember, do not increase your dosage" (Read Review). Another user mentioned giving a lozenge to their husband in the morning after meals, resulting in the cough disappearing after three days (Read Review).
Several reviews support the efficacy of zinc for cough relief, indicating that users typically take it during cold or flu seasons or at the first signs of symptoms. For example, one user effectively used zinc after noticing early cold symptoms, stating that taking one capsule after dinner led to no cough or runny nose the next morning (Read Review). Overall, users appear to favor a cautious approach with dosages, often opting for periodic use when symptoms arise, and suggesting that even within that framework, zinc has been effective in alleviating coughs.
10
Rapid cough cure
I began giving my husband one lozenge in the morning after eating when he started coughing; after three days, the cough was gone!
10
Quick cough relief
I bought these lozenges due to their high potency for coronavirus protection. One night, I had a persistent cough, but after taking a lozenge, the cough disappeared within seconds! The next morning, I experienced taste loss, which worried me, but I remembered that the lozenges can cause this temporary effect.
9
First symptom relief
Excellent! I've taken this several times; it helps with early cold symptoms! One capsule after dinner, and no cough or runny nose in the morning.
9
Cough prevention
4 people found this helpful
I drink zinc periodically since last year, and this one is much better than those from pharmacies. Remember, do not increase your dosage. After taking this zinc, I’ve completely forgotten about coughing. It really works without any doubt.
10
Chronic cough help
Very effective for coughing, particularly for those with chronic bronchitis. This zinc did not cause any allergies, unlike some Russian drugs I tried.
9
Cough relief
2 people found this helpful
I liked it! An essential vitamin for maintaining immunity. My husband and I take it periodically, especially during the coronavirus and cold season. I even give it to my daughter when she begins coughing, and it helps prevent the cough from worsening! I recommend it!
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
References
Balasubramanian A, Holbrook JT, Canning BJ, Que LG, Castro M, et al. Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial. ERJ Open Res. 2023;9. doi:10.1183/23120541.00678-2022
Nishi K, Yoshimoto S, Tanaka T, Kimura S, Shinchi Y, et al. A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy. Cureus. 2023;15:e33421. doi:10.7759/cureus.33421
Kumar GS, Vadgaonkar A, Purunaik S, Shelatkar R, Vaidya VG, et al. Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial. Cureus. 2022;14:e25467. doi:10.7759/cureus.25467