Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 40 Reviews
8.9
Supplement Facts
Serving Size: 2 tablets
Amount Per Serving
%DV
Pancreatic EnzymesUsp Units Of Activity:Amylase 81,250 UspProtease 81,250 UspLipase 6,500 Usp
361 mg
**
Trypsin
75 mg
**
Papain
50 mg
**
Bromelain
16 mg
**
Amylase
10 mg
**
Lipase
10 mg
**
Chymotrypsin
2 mg
**

Top Medical Research Studies

7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.

The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.

While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
Read More
7
Improvement in post-surgical GI symptoms
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.

After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
Read More

Most Useful Reviews

9.5
Relief from bloating
Excellent enzymes with probiotics that aid in digestion and nutrient absorption. I no longer experience bloating, heaviness, or nausea after meals. This product works much better for me than other digestive enzymes, making it a valuable addition to my first-aid kit.
Read More
8.3
Optimal results
This enzyme works effectively for digestion and has helped alleviate my bloating. However, I recommend introducing it gradually alongside sorbents, as it initially caused some discomfort.
Read More
10
Excellent for bloating
After three weeks of using Mega-Zyme, my health has improved greatly. No more bloating, pain, or heaviness—my stool is well-formed. I highly recommend this enzyme preparation for anyone experiencing similar issues.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
  • All Researches
7
Improvement in post-surgical GI symptoms
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.

After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
Read More
7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.

The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.

While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 40 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Relief from bloating
Excellent enzymes with probiotics that aid in digestion and nutrient absorption. I no longer experience bloating, heaviness, or nausea after meals. This product works much better for me than other digestive enzymes, making it a valuable addition to my first-aid kit.
Read More
8.3
Optimal results
This enzyme works effectively for digestion and has helped alleviate my bloating. However, I recommend introducing it gradually alongside sorbents, as it initially caused some discomfort.
Read More
10
Excellent for bloating
After three weeks of using Mega-Zyme, my health has improved greatly. No more bloating, pain, or heaviness—my stool is well-formed. I highly recommend this enzyme preparation for anyone experiencing similar issues.
Read More
10
Relief achieved
Real relief. Finally, I can eat any meal, and as long as I take two tabs right before or with my meal, the dreadful bloating, pain, and gas have become a thing of the past. I will be ordering it again and want to thank you for having it available!
Read More
9
Helps alleviate bloating
I found Mega-Zyme to be highly effective. It significantly speeds up digestion and eliminates gas and bloating. I take two capsules before every meal, and it has made a noticeable difference in my digestion.
Read More

Frequently Asked Questions

Bloating is a common gastrointestinal condition characterized by a sensation of fullness, tightness, or swelling in the abdomen. It often occurs after eating and can be accompanied by visible distension of the belly. This discomfort may be caused by various factors, including excessive gas production, food intolerances, overeating, or certain medical conditions affecting the digestive system. Many people experience bloating occasionally, but when it becomes chronic, it can significantly impact one's quality of life.

Managing bloating typically involves dietary adjustments, such as identifying and avoiding trigger foods, eating smaller meals, and incorporating more fiber into your diet. Staying hydrated and engaging in regular physical activity can also help alleviate symptoms. If bloating is persistent or accompanied by other troubling symptoms like severe pain or changes in bowel habits, it is advisable to consult a healthcare professional for proper evaluation and guidance.

Pancreatin is a digestive enzyme supplement made from the extracts of the pancreas of animals, usually pigs or cows. It contains a mixture of enzymes, including amylase, lipase, and protease, which help in the breakdown of carbohydrates, fats, and proteins in the digestive tract. This supplement is particularly beneficial for individuals with pancreatic insufficiency, a condition where the pancreas does not produce enough digestive enzymes. Patients with conditions such as cystic fibrosis, chronic pancreatitis, or those who have undergone pancreatic surgery may benefit from taking pancreatin to improve nutrient absorption and alleviate digestive discomfort.

Pancreatin is available in various forms, including tablets, capsules, and powders. When considering incorporating pancreatin into your diet, it's important to consult with a healthcare professional, as they can provide guidance on appropriate dosing and potential interactions with other medications. Additionally, some people may experience side effects such as gastrointestinal upset or allergic reactions, so it's essential to monitor your response to the supplement. With proper use, pancreatin can be a valuable tool in managing digestive health and ensuring that your body effectively absorbs essential nutrients.

Pancreatin, a combination of digestive enzymes including amylase, lipase, and protease, is primarily used to aid digestion, especially in individuals with conditions that impair the pancreas. It is often recommended for those suffering from pancreatic insufficiency, which can occur in diseases like pancreatitis or cystic fibrosis. While pancreatin is not specifically indicated for bloating, some users report that it helps alleviate symptoms of bloating by improving overall digestion and nutrient absorption. By breaking down carbohydrates, proteins, and fats more effectively, pancreatin may reduce the fermentation of undigested food in the gut, potentially leading to less gas and bloating.

However, it’s essential to approach the use of pancreatin with caution. Users should consult with a healthcare professional before integrating it into their routine, particularly if they are experiencing persistent bloating. Bloating can be caused by a variety of factors, including food intolerances, gastrointestinal disorders, or even lifestyle choices. While pancreatin may be beneficial for some, it is not a one-size-fits-all solution. Monitoring whether symptoms improve after taking pancreatin, along with professional guidance, will ensure safe and effective management of digestive issues.

Based on user reviews, the time it typically takes to see results from taking this supplement for bloating can vary. Many users report noticeable improvements within a couple of weeks. For instance, one reviewer noted positive results after just two weeks of use, highlighting the supplement's effectiveness in relieving heaviness and bloating (Read Review). Similarly, another user mentioned significant digestive health improvements and the elimination of bloating after three weeks (Read Review).

Conversely, some users take longer to experience the full benefits, with others noting improvements after two months of consistent use. For example, one reviewer shared that after two months, not only had their digestion improved, but they no longer experienced any bloating or discomfort (Read Review). It appears that individual experiences can vary, so results may be felt sooner for some while taking longer for others. Overall, if you're looking for relief from bloating, considering a timeline of a few weeks to a couple of months may be prudent.

There is compelling research supporting the use of certain supplements for alleviating bloating, particularly probiotics, digestive enzymes, and spasmocanulase. A study examining the efficacy of these treatments post-gastric bypass surgery demonstrated significant improvements in bloating and gas symptoms among patients who received either probiotics or digestive enzymes, such as pancreatin, over a two-week period [1]. This indicates that such supplements may enhance quality of life for those dealing with gastrointestinal issues.

Additionally, spasmocanulase has shown promise in addressing bloating symptoms associated with irritable bowel syndrome (IBS). In a clinical trial involving patients resistant to other medications, spasmocanulase was administered three times daily for six months, leading to relief from bloating in 43-75% of participants [2]. While these studies suggest potential benefits, it's essential to consider individual responses and consult with a healthcare professional for personalized advice.

Based on user reviews, many individuals report significant improvements in their symptoms after using Mega-Zyme, particularly in relation to bloating and digestive discomfort. Users commonly mention that the product helps alleviate feelings of heaviness, nausea, and bloating after meals. For example, one reviewer expressed that their bloating, heaviness, and nausea have all disappeared, crediting the enzymes as a better alternative than previous digestive aids they tried (Read Review). Others have noted immediate results, with several users highlighting the disappearance of bloated sensations almost immediately after taking the supplement, especially if taken with meals (Read Review).

Further anecdotal evidence supports the claim that these enzymes can enhance digestive health overall. For instance, one user reported a reduction in symptoms related to IBS and indicated that the feeling of bloating vanished shortly after they started using the product (Read Review). Additionally, others have highlighted notable improvements in bowel movements and overall comfort in the digestive system, reinforcing that while individual results can vary, many seem to experience significant relief from bloating and related issues relatively quickly after starting Mega-Zyme (Read Review).

Users report a variety of experiences when combining Mega-Zyme with other supplements to address bloating. Some have found it useful to introduce the enzyme gradually alongside sorbents to mitigate any initial discomfort, suggesting that a cautious approach can maximize benefits without adverse effects (Read Review). Others recommend taking Mega-Zyme in conjunction with a gastrointestinal treatment plan, noting that doing so provided immediate relief from bloating and improved digestive comfort (Read Review).

Overall, users emphasize the importance of taking Mega-Zyme as directed, often before meals, for optimal effectiveness in alleviating symptoms of bloating. Many mention that its integration with their overall supplement regimen has led to significant improvements in digestion and a reduction in bloated sensations, reinforcing its role in enhancing digestive health (Read Review). However, since individual reactions can vary, it's advisable for users to monitor their responses when combining supplements (Read Review).

Based on user reviews, there seems to be a consensus regarding the effective dosage of Pancreatin for alleviating bloating. Many users have reported taking around two capsules with meals, which they found to be effective in reducing bloating and discomfort. For instance, one user mentioned that after initially taking too much, they adjusted to two capsules after meals, experiencing immediate relief from bloating concerns (Read Review). Others echoed this sentiment, claiming that taking two capsules before each meal significantly improved their digestive discomfort and bloating issues (Read Review).

Additionally, some users reported benefits from taking a single capsule before meals, particularly for those who experience bloating related to rich foods (Read Review). However, there is a cautionary note among a few, as one user suggested introducing the enzyme gradually to avoid initial discomfort (Read Review). Overall, it appears that a dose of one to two capsules taken before or with meals is commonly preferred among users seeking relief from bloating.

9.5
Effective for digestion
Mega-Zyme is the best enzyme complex I’ve tried. Taken on an empty stomach, it enhances metabolism and detoxification, and with food, it aids digestion, relieving heaviness and bloating. I've noticed positive results after two weeks and recommend it to everyone.
10
Excellent for bloating
After three weeks of using Mega-Zyme, my health has improved greatly. No more bloating, pain, or heaviness—my stool is well-formed. I highly recommend this enzyme preparation for anyone experiencing similar issues.
9
Reduced bloating
After two months of use, I've noted a reduction in my paraovular cyst and a significant anti-inflammatory effect. My digestion is much improved, and I no longer experience any bloating or discomfort.
9.5
Relief from bloating
Excellent enzymes with probiotics that aid in digestion and nutrient absorption. I no longer experience bloating, heaviness, or nausea after meals. This product works much better for me than other digestive enzymes, making it a valuable addition to my first-aid kit.
8.8
Bloating disappears
I have IBS, which causes digestive issues. A colleague suggested Mega-Zyme, and it complements my usual medications well. Even if taken post-meal, the bloated feeling vanishes almost immediately. When I forget them, I notice the difference and regret it. These pills are now a part of my daily routine!
9.5
Light stomach
This is an excellent product. I used to suffer from bloating and gas after meals, but since I started taking these enzymes, I feel a sense of lightness in my stomach and intestines.
8.3
Optimal results
This enzyme works effectively for digestion and has helped alleviate my bloating. However, I recommend introducing it gradually alongside sorbents, as it initially caused some discomfort.
9.5
Bloating relief
Prescribed alongside my gastrointestinal treatment, I initially took too much but adjusted to two capsules after meals. The effects were immediate, calming my stomach and resolving my bloating concerns.
9.5
Cleanses the system
Mega-Zyme taken with meals supports digestion and alleviates bloating. Used differently on an empty stomach, it aids in systemic cleansing, acting as a cleaner for tissues. Its benefits extend throughout the body.
9
Helps alleviate bloating
I found Mega-Zyme to be highly effective. It significantly speeds up digestion and eliminates gas and bloating. I take two capsules before every meal, and it has made a noticeable difference in my digestion.
9.5
Bloating relief
I’m very pleased with these digestive enzymes. Taking them before meals noticeably reduces bloating and discomfort, especially after rich foods. I’ve had no side effects and will repurchase.
7
Improvement in post-surgical GI symptoms
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.

After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.

The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.

While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.

References

  1. Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. doi:10.1016/j.soard.2015.07.010
  2. Mohamed AE, Ghandour ZM, Al-Karawi MA. Spasmocanulase in irritable bowel syndrome. Saudi Med J. 2002;23:1074.
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