Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size: 2 tablets
Amount Per Serving
%DV
Pancreatic EnzymesUsp Units Of Activity:Amylase 81,250 UspProtease 81,250 UspLipase 6,500 Usp
361 mg
**
Trypsin
75 mg
**
Papain
50 mg
**
Bromelain
16 mg
**
Amylase
10 mg
**
Lipase
10 mg
**
Chymotrypsin
2 mg
**
Top Medical Research Studies
8
Pancreatin improves nutritional status
We evaluated pancreatic enzyme replacement therapy (PERT) that uses microencapsulated pancreatin in enhancing nutritional status among patients with chronic pancreatitis (CP) and exocrine pancreatic insufficiency (EPI).
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
Read More
7
We examined the case of a 50-year-old man dealing with chronic pancreatitis who developed pancreatic diabetes after surgery. His treatment included insulin along with pancreatin and essential micronutrients.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
Read More
8
We investigated how adding exogenous pancreatin affects piglets' growth and nutrient absorption. In a carefully designed study with 180 piglets, we randomly assigned them to three groups: one receiving no pancreatin and the others getting 250 or 500 mg/kg.
The results showed that the piglets on the 500 mg/kg pancreatin diet had a noticeable increase in daily weight gain and better nutrient digestibility. Additionally, the treated piglets exhibited enhanced enzyme activity and improved intestinal structures.
Overall, our findings suggest that 500 mg/kg of pancreatin significantly boosts growth and digestibility, benefiting the piglets' overall health.
The results showed that the piglets on the 500 mg/kg pancreatin diet had a noticeable increase in daily weight gain and better nutrient digestibility. Additionally, the treated piglets exhibited enhanced enzyme activity and improved intestinal structures.
Overall, our findings suggest that 500 mg/kg of pancreatin significantly boosts growth and digestibility, benefiting the piglets' overall health.
Read More
Most Useful Reviews
9
Excellent improvement
18 people found this helpful
I experienced pain in the hypochondria and discovered I had pancreatitis with poor bile outflow. After three weeks of taking the drug, my health has improved significantly. There's no bloating, pain, or nausea, and my stools are normalised in colour and consistency. I can confidently recommend Mega-Zyme as an exceptional enzyme preparation.
Read More
9
Symptoms managed well
1 people found this helpful
I've been taking these enzymes, along with Pan 10X, for about two years to control my pancreatitis, which made it difficult to eat high-fat or sugary foods. These enzymes have been a lifeline for managing my regulated diet and have significantly reduced the painful symptoms of pancreatitis, with no negative side effects. I highly recommend them for anyone dealing with digestive issues.
Read More
9
Effective solution
I've tried various enzymes but was pleased with this one, as it notably includes trypsin, which is beneficial for my chronic pancreatitis. I wasn't disappointed with the results.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
- All Researches
8
We investigated how adding exogenous pancreatin affects piglets' growth and nutrient absorption. In a carefully designed study with 180 piglets, we randomly assigned them to three groups: one receiving no pancreatin and the others getting 250 or 500 mg/kg.
The results showed that the piglets on the 500 mg/kg pancreatin diet had a noticeable increase in daily weight gain and better nutrient digestibility. Additionally, the treated piglets exhibited enhanced enzyme activity and improved intestinal structures.
Overall, our findings suggest that 500 mg/kg of pancreatin significantly boosts growth and digestibility, benefiting the piglets' overall health.
The results showed that the piglets on the 500 mg/kg pancreatin diet had a noticeable increase in daily weight gain and better nutrient digestibility. Additionally, the treated piglets exhibited enhanced enzyme activity and improved intestinal structures.
Overall, our findings suggest that 500 mg/kg of pancreatin significantly boosts growth and digestibility, benefiting the piglets' overall health.
Read More
8
High-dose enzymes and NAFLD prevention
We explored whether high-dose digestive enzymes could help prevent nonalcoholic fatty liver disease (NAFLD) after pancreaticoduodenectomy.
In this randomized clinical trial, patients who underwent surgery were assigned to receive either normal or high doses of digestive enzymes.
Our findings showed that high-dose enzymes significantly reduced the development of NAFLD when compared to normal doses, marking a positive outcome for those recovering from surgery.
In this randomized clinical trial, patients who underwent surgery were assigned to receive either normal or high doses of digestive enzymes.
Our findings showed that high-dose enzymes significantly reduced the development of NAFLD when compared to normal doses, marking a positive outcome for those recovering from surgery.
Read More
8
Pancreatin improves nutritional status
We evaluated pancreatic enzyme replacement therapy (PERT) that uses microencapsulated pancreatin in enhancing nutritional status among patients with chronic pancreatitis (CP) and exocrine pancreatic insufficiency (EPI).
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
Read More
7
We examined the case of a 50-year-old man dealing with chronic pancreatitis who developed pancreatic diabetes after surgery. His treatment included insulin along with pancreatin and essential micronutrients.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Excellent improvement
18 people found this helpful
I experienced pain in the hypochondria and discovered I had pancreatitis with poor bile outflow. After three weeks of taking the drug, my health has improved significantly. There's no bloating, pain, or nausea, and my stools are normalised in colour and consistency. I can confidently recommend Mega-Zyme as an exceptional enzyme preparation.
Read More
9
Symptoms managed well
1 people found this helpful
I've been taking these enzymes, along with Pan 10X, for about two years to control my pancreatitis, which made it difficult to eat high-fat or sugary foods. These enzymes have been a lifeline for managing my regulated diet and have significantly reduced the painful symptoms of pancreatitis, with no negative side effects. I highly recommend them for anyone dealing with digestive issues.
Read More
9
Effective solution
I've tried various enzymes but was pleased with this one, as it notably includes trypsin, which is beneficial for my chronic pancreatitis. I wasn't disappointed with the results.
Read More
7.5
Improved digestion control
7 people found this helpful
I ended up in the ER with severe pancreatitis and spent a week in hospital. Knowing changes were needed, I started using pancreatic enzymes without a prescription, following the directions diligently. My diet had to adjust due to new challenges, but I'm feeling better and more in control now. The larger size bottle helps me estimate my needs for the coming months. It's an amazing feeling to regain body confidence after a hospital stay. I highly recommend this for anyone, especially older adults with digestive issues.
Read More
7.5
Stops diarrhea effectively
6 people found this helpful
Great for pancreatitis! They work wonderfully for me and stop my diarrhoea.
Read More
Frequently Asked Questions
9
Excellent improvement
18 people found this helpful
I experienced pain in the hypochondria and discovered I had pancreatitis with poor bile outflow. After three weeks of taking the drug, my health has improved significantly. There's no bloating, pain, or nausea, and my stools are normalised in colour and consistency. I can confidently recommend Mega-Zyme as an exceptional enzyme preparation.
9
Effective solution
I've tried various enzymes but was pleased with this one, as it notably includes trypsin, which is beneficial for my chronic pancreatitis. I wasn't disappointed with the results.
7.5
Digestive aid
1 people found this helpful
I take digestive enzymes to assist with digestion and feel light after meals. I've also used them as a preventative measure for pancreatitis. Although I prefer vegetable options for regular use, these enzymes work well before meals.
7.5
Improves digestion
This medication enhances digestion for those who experience heaviness, bloating, or belching after meals. It's suitable for long-term use without addiction. I recommend it for chronic pancreatitis or similar digestive issues.
6
Slight improvement
I administered the enzymes for my husband who suffers from pancreatitis and cholecystitis. His digestion and stool showed slight improvement.
7.5
Feeling great
I take these enzymes with meat for my low acidity and chronic cholecystitis and pancreatitis, and they make me feel wonderful.
8
Pancreatin improves nutritional status
We evaluated pancreatic enzyme replacement therapy (PERT) that uses microencapsulated pancreatin in enhancing nutritional status among patients with chronic pancreatitis (CP) and exocrine pancreatic insufficiency (EPI).
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
This study included 58 participants, split into two groups based on their nutritional status. Over 8-12 months, both groups received the therapy while we assessed changes in body weight, BMI, and laboratory indicators of nutrition before and after treatment.
Impressively, we found that PERT effectively improved nutritional status in patients suffering from CP.
7
We examined the case of a 50-year-old man dealing with chronic pancreatitis who developed pancreatic diabetes after surgery. His treatment included insulin along with pancreatin and essential micronutrients.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
Remarkably, we observed improvements in his diarrhea and blood glucose levels. This case highlights the importance of recognizing pancreatic diabetes that can emerge after pancreatitis or pancreatic surgery, suggesting that timely intervention can help mitigate complications.
However, it's essential to note that while pancreatin played a role in managing symptoms, it was part of a broader treatment approach.
References
- Song A, Zhang R, Chi Y, Zhang HB. [The 501st case: elevated blood glucose, chronic pancreatitis, and post- pancreatoduodenectomy malnutrition]. Zhonghua Nei Ke Za Zhi. 2023;62:891. doi:10.3760/cma.j.cn112138-20221120-00870
- Liu X, Huang X, Fu Y, Wang Y, Lu Z. The Positive Effects of Exogenous Pancreatin on Growth Performance, Nutrient Digestion and Absorption, and Intestinal Microbiota in Piglets. Front Physiol. 2022;13:906522. doi:10.3389/fphys.2022.906522
- Yasukawa K, Shimizu A, Yokoyama T, Kubota K, Notake T, et al. Preventive Effect of High-Dose Digestive Enzyme Management on Development of Nonalcoholic Fatty Liver Disease after Pancreaticoduodenectomy: A Randomized Controlled Clinical Trial. J Am Coll Surg. 2020;231:658. doi:10.1016/j.jamcollsurg.2020.08.761
- Bideeva TV, Maev IV, Kucheryavyy YA, Andreev DN, Shah YS, et al. [The effectiveness of pancreatic enzyme replacement therapy using microencapsulated pancreatin preparations in the correction of nutritional status in patients with chronic pancreatitis: a prospective observational study]. Ter Arkh. 2020;92:30. doi:10.26442/00403660.2020.01.000488
