'
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Milk Thistle extract (seed) standardized to 80% silymarin (140 mg)
175 mg
**

Top Medical Research Studies

9
Silybum marianum reduces acne severity
Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention.
Highly relevant acne prevention study
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
Tolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study.
Relevance score: average effectiveness
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.

While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More
9
Effective, but limited by other treatments
Long-Term Use of Contributes to Homeostasis in Acne-Prone Skin-A 12-Month Follow-Up International "Real Life" Cohort Study.
High relevance, real-life results.
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.

We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.

However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More

Most Useful Reviews

9.5
Cleared back acne
Cured acne on back. This product helped clear up acne on my back. I am very pleased with it and will be purchasing more.
Read More
9.5
Cleared adult acne
Helped Clear up Adult Acne. I struggled with adult hormonal acne on my chin for two months and couldn't eliminate it. After purchasing Burdock Root, Milk Thistle, and Vitex from Amazon, and taking them twice daily, my skin looks great!
Read More
8.8
Avoids hormonal acne
Clear Skin. I use this alongside other herbs to help my skin and avoid hormonal acne. I've used it for three months and saw results after two.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
9
Effective, but limited by other treatments
Long-Term Use of Contributes to Homeostasis in Acne-Prone Skin-A 12-Month Follow-Up International "Real Life" Cohort Study.
High relevance, real-life results.
This year-long study involved 54 teenagers and young adults with mild to moderate facial acne, exploring the effects of silybum marianum in real-life situations.

We found impressive results, with a 45.6% decrease in acne lesions after six months and 59.6% after twelve months. Overall, the treatment improved skin health significantly, even with minimal use of standard acne medications.

However, we should note that the influence of silybum marianum alone is hard to quantify due to the small percentage of other acne treatments utilized during the study.
Read More
9
Silybum marianum reduces acne severity
Microcomedones in non-lesional acne prone skin New orientations on comedogenesis and its prevention.
Highly relevant acne prevention study
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.

Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Read More
7
Effectiveness of Silybum marianum on acne
Tolerability and effectiveness of a dermocosmetic product containing Silybum marianum fruit extract in adolescents and young adults with acne-prone skin: An international, phase IV, longitudinal study.
Relevance score: average effectiveness
We examined the effectiveness and tolerance of a dermocosmetic product containing Silybum marianum fruit extract in treating acne in adolescents and young adults. In an international study with over 4,200 participants aged 12 to 25, the product was used twice daily for 8 to 12 weeks. It was applied alone, after medical therapy, or alongside other treatments.

While the product showed promise in managing acne, its role appears more supportive than curative, helping to reduce reliance on traditional anti-acne medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Cleared back acne
Cured acne on back. This product helped clear up acne on my back. I am very pleased with it and will be purchasing more.
9.5
Cleared adult acne
Helped Clear up Adult Acne. I struggled with adult hormonal acne on my chin for two months and couldn't eliminate it. After purchasing Burdock Root, Milk Thistle, and Vitex from Amazon, and taking them twice daily, my skin looks great!
8.8
Avoids hormonal acne
Clear Skin. I use this alongside other herbs to help my skin and avoid hormonal acne. I've used it for three months and saw results after two.
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