5/20/2025
Last update
5/20/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.5
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from fish [liver] oil, retinyl palmitate)
3,000 mcg
333%
Top Medical Research Studies
9
We conducted a thorough investigation into how vitamin A supplementation might impact thyroid function, particularly focusing on women who are premenopausal and have varying body weights. Our study was a robust, four-month randomized controlled trial involving 84 healthy women aged 17 to 50. Among them, 56 women were classified as obese, while 28 fell into the nonobese category.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
Read More
8
We aimed to understand how vitamin A deficiency (VAD) and its supplementation can affect thyroid function in children living in areas with goiter issues. In a double-blind, randomized trial, we followed 138 Moroccan children who received either vitamin A or a placebo alongside iodized salt for ten months. Our results showed that higher levels of VAD correlated with increased thyroid volume and TSH levels, while vitamin A supplementation led to significant reductions in these factors. Overall, vitamin A appears beneficial in improving thyroid function in children affected by iodine deficiency.
Read More
8
We explored the impact of vitamin A supplementation on hypothyroidism in the context of concurrent vitamin A and iodine deficiencies. In our study, we used weanling rats, some of whom were fed diets lacking both vitamin A and iodine for 30 days before we administered treatments. This allowed us to set up a clear comparison between the effects of vitamin A alone, iodine alone, and combinations of both against a control group that received a nutrient-rich diet.
After we deprived the rats of these crucial nutrients, we repleted them with iodine and/or vitamin A for 10 days. What we found was quite interesting: while high doses of vitamin A restored serum retinol levels to normal, the key effects on thyroid function were observed mainly in the iodine-deficient rats. Here, vitamin A supplementation led to decreased production of thyroid-stimulating hormone (TSH) from the pituitary gland, effectively reducing thyroid stimulation and size without significantly altering circulating thyroid hormone levels.
Conversely, in rats that received sufficient iodine, vitamin A didn’t have any noticeable impact on the thyroid-pituitary function, indicating that the thyroid responses were largely dictated by iodine presence. Overall, our results suggest that vitamin A can modify thyroid hyperactivity caused by iodine deficiency, emphasizing its role in managing such deficiencies, even when iodine is not adequate. We observed that vitamin A’s influence might operate through its effects on pituitary TSHbeta gene expression—a point worthy of further exploration.
After we deprived the rats of these crucial nutrients, we repleted them with iodine and/or vitamin A for 10 days. What we found was quite interesting: while high doses of vitamin A restored serum retinol levels to normal, the key effects on thyroid function were observed mainly in the iodine-deficient rats. Here, vitamin A supplementation led to decreased production of thyroid-stimulating hormone (TSH) from the pituitary gland, effectively reducing thyroid stimulation and size without significantly altering circulating thyroid hormone levels.
Conversely, in rats that received sufficient iodine, vitamin A didn’t have any noticeable impact on the thyroid-pituitary function, indicating that the thyroid responses were largely dictated by iodine presence. Overall, our results suggest that vitamin A can modify thyroid hyperactivity caused by iodine deficiency, emphasizing its role in managing such deficiencies, even when iodine is not adequate. We observed that vitamin A’s influence might operate through its effects on pituitary TSHbeta gene expression—a point worthy of further exploration.
Read More
Most Useful Reviews
7.5
Effective treatment
206 people found this helpful
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.
Read More
7.5
Vitamin A benefits
3 people found this helpful
I recommend this product! It’s a great source of Vitamin A for those with hypothyroidism who can’t convert beta carotene. Good quality and value for money.
Read More
9
Crucial for treatment
1 people found this helpful
Vitamin A is an antioxidant essential for the immune system, bone tissue, reproductive health, vision, and skin. It reduces TSH synthesis and enhances iodine absorption in hypothyroidism. However, smokers should limit their intake to 3000 IU per day.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.5
- All Researches
9
We conducted a thorough investigation into how vitamin A supplementation might impact thyroid function, particularly focusing on women who are premenopausal and have varying body weights. Our study was a robust, four-month randomized controlled trial involving 84 healthy women aged 17 to 50. Among them, 56 women were classified as obese, while 28 fell into the nonobese category.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
Read More
9
We observed a case of a German Warmblood gelding exhibiting signs of keratoconjunctivitis sicca and other neurological symptoms, which were ultimately linked to hypothyroidism. As part of the treatment for this condition, vitamin A ointment was applied topically to the horse's eyes, alongside other therapies.
While vitamin A is traditionally known for its role in maintaining healthy eyes, the specific effectiveness of vitamin A in treating hypothyroidism remains unclear in this case. The primary treatment involved levothyroxine, which significantly improved the horse's thyroid function and correlated with the resolution of many clinical signs, including the eye issues.
Thus, while vitamin A was included in the treatment regimen, its distinct impact on the overall condition cannot be confidently isolated from the benefits observed with levothyroxine therapy. This underscores the need for more controlled studies to better understand the interplay between vitamin A and thyroid health.
While vitamin A is traditionally known for its role in maintaining healthy eyes, the specific effectiveness of vitamin A in treating hypothyroidism remains unclear in this case. The primary treatment involved levothyroxine, which significantly improved the horse's thyroid function and correlated with the resolution of many clinical signs, including the eye issues.
Thus, while vitamin A was included in the treatment regimen, its distinct impact on the overall condition cannot be confidently isolated from the benefits observed with levothyroxine therapy. This underscores the need for more controlled studies to better understand the interplay between vitamin A and thyroid health.
Read More
8
Vitamin A supports thyroid function
We explored the relationship between vitamin A deficiency (VAD) and hypothyroidism, particularly how these deficiencies impact the pituitary-thyroid axis in the body. Our understanding comes from various studies, including those involving children in Africa, where VAD combined with iodine deficiency disorders (IDD) often leads to unique hormonal responses.
In children suffering from both VAD and IDD, we observed that higher levels of thyroid-stimulating hormone (TSH) may actually help in preventing hypothyroidism, despite existing conditions. Interestingly, research in rats showed that moderate VAD alone did not significantly affect the pituitary-thyroid axis. However, when VAD accompanies iodine deficiency, it can lead to more serious cases of primary hypothyroidism than iodine deficiency on its own.
When it comes to treatment, we noted that high doses of vitamin A could correct thyroid dysfunction caused by iodine deficiency. Therefore, while vitamin A does play a role, it doesn't diminish the effectiveness of iodine repletion. Our findings suggest that vitamin A supplementation can help manage thyroid stimulation, especially in individuals affected by both deficiencies.
Thus, we can conclude that while vitamin A isn’t a standalone solution for hypothyroidism, it certainly plays a supportive role in improving treatment outcomes when iodine levels are restored.
In children suffering from both VAD and IDD, we observed that higher levels of thyroid-stimulating hormone (TSH) may actually help in preventing hypothyroidism, despite existing conditions. Interestingly, research in rats showed that moderate VAD alone did not significantly affect the pituitary-thyroid axis. However, when VAD accompanies iodine deficiency, it can lead to more serious cases of primary hypothyroidism than iodine deficiency on its own.
When it comes to treatment, we noted that high doses of vitamin A could correct thyroid dysfunction caused by iodine deficiency. Therefore, while vitamin A does play a role, it doesn't diminish the effectiveness of iodine repletion. Our findings suggest that vitamin A supplementation can help manage thyroid stimulation, especially in individuals affected by both deficiencies.
Thus, we can conclude that while vitamin A isn’t a standalone solution for hypothyroidism, it certainly plays a supportive role in improving treatment outcomes when iodine levels are restored.
Read More
8
We explored the impact of vitamin A supplementation on hypothyroidism in the context of concurrent vitamin A and iodine deficiencies. In our study, we used weanling rats, some of whom were fed diets lacking both vitamin A and iodine for 30 days before we administered treatments. This allowed us to set up a clear comparison between the effects of vitamin A alone, iodine alone, and combinations of both against a control group that received a nutrient-rich diet.
After we deprived the rats of these crucial nutrients, we repleted them with iodine and/or vitamin A for 10 days. What we found was quite interesting: while high doses of vitamin A restored serum retinol levels to normal, the key effects on thyroid function were observed mainly in the iodine-deficient rats. Here, vitamin A supplementation led to decreased production of thyroid-stimulating hormone (TSH) from the pituitary gland, effectively reducing thyroid stimulation and size without significantly altering circulating thyroid hormone levels.
Conversely, in rats that received sufficient iodine, vitamin A didn’t have any noticeable impact on the thyroid-pituitary function, indicating that the thyroid responses were largely dictated by iodine presence. Overall, our results suggest that vitamin A can modify thyroid hyperactivity caused by iodine deficiency, emphasizing its role in managing such deficiencies, even when iodine is not adequate. We observed that vitamin A’s influence might operate through its effects on pituitary TSHbeta gene expression—a point worthy of further exploration.
After we deprived the rats of these crucial nutrients, we repleted them with iodine and/or vitamin A for 10 days. What we found was quite interesting: while high doses of vitamin A restored serum retinol levels to normal, the key effects on thyroid function were observed mainly in the iodine-deficient rats. Here, vitamin A supplementation led to decreased production of thyroid-stimulating hormone (TSH) from the pituitary gland, effectively reducing thyroid stimulation and size without significantly altering circulating thyroid hormone levels.
Conversely, in rats that received sufficient iodine, vitamin A didn’t have any noticeable impact on the thyroid-pituitary function, indicating that the thyroid responses were largely dictated by iodine presence. Overall, our results suggest that vitamin A can modify thyroid hyperactivity caused by iodine deficiency, emphasizing its role in managing such deficiencies, even when iodine is not adequate. We observed that vitamin A’s influence might operate through its effects on pituitary TSHbeta gene expression—a point worthy of further exploration.
Read More
8
We explored the effects of retinoic acid (RA) on brain function in a model of mild hypothyroidism induced by propylthiouracil (PTU) in mice. This research sought to understand whether RA could counteract the decline in certain brain markers associated with thyroid hormone changes, specifically neurogranin, which is linked to brain plasticity and cognitive function.
In the study, we observed that the administration of RA helped restore the expression of several key receptors and neurogranin levels that had decreased due to PTU treatment. Specifically, both RA and the thyroid hormone triiodothyronine (T3) were effective in reversing reductions in receptor expression, suggesting that RA has a beneficial impact under conditions of mild hypothyroidism.
We were careful to note that while RA showed potential in normalizing some brain functions, the exact mechanisms and broader implications of this treatment warrant further exploration. These findings provide exciting insights into how retinoic acid may play a role in brain health, especially in the context of thyroid hormone related changes that can occur as we age.
In the study, we observed that the administration of RA helped restore the expression of several key receptors and neurogranin levels that had decreased due to PTU treatment. Specifically, both RA and the thyroid hormone triiodothyronine (T3) were effective in reversing reductions in receptor expression, suggesting that RA has a beneficial impact under conditions of mild hypothyroidism.
We were careful to note that while RA showed potential in normalizing some brain functions, the exact mechanisms and broader implications of this treatment warrant further exploration. These findings provide exciting insights into how retinoic acid may play a role in brain health, especially in the context of thyroid hormone related changes that can occur as we age.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Effective treatment
206 people found this helpful
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.
Read More
7.5
Vitamin A benefits
3 people found this helpful
I recommend this product! It’s a great source of Vitamin A for those with hypothyroidism who can’t convert beta carotene. Good quality and value for money.
Read More
9
Crucial for treatment
1 people found this helpful
Vitamin A is an antioxidant essential for the immune system, bone tissue, reproductive health, vision, and skin. It reduces TSH synthesis and enhances iodine absorption in hypothyroidism. However, smokers should limit their intake to 3000 IU per day.
Read More
9
Positive results
I recommend this vitamin A for my hypothyroidism. I took three capsules daily for two months, and the results have been excellent. A doctor advised me to use this brand.
Read More
8
Notable improvement
A nutritionist prescribed this for my hypothyroidism, and I’ve noticed a significant improvement. I’ll continue my course of treatment!
Read More
Frequently Asked Questions
9
Positive results
I recommend this vitamin A for my hypothyroidism. I took three capsules daily for two months, and the results have been excellent. A doctor advised me to use this brand.
8
Notable improvement
A nutritionist prescribed this for my hypothyroidism, and I’ve noticed a significant improvement. I’ll continue my course of treatment!
9
Crucial for treatment
1 people found this helpful
Vitamin A is an antioxidant essential for the immune system, bone tissue, reproductive health, vision, and skin. It reduces TSH synthesis and enhances iodine absorption in hypothyroidism. However, smokers should limit their intake to 3000 IU per day.
7.5
Effective treatment
206 people found this helpful
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.
6
Careful dosage
83 people found this helpful
Understand the possible toxicity; beta carotene has few restrictions and can cause slight yellowing, while retinol accumulates and can be toxic. If deficient, it’s wise to have a course of vitamins. Retinol deficiency is prevalent in hypothyroidism due to conversion issues; I take one capsule every two days.
7.5
Monitor intake
Beta carotene transforms into retinol in the body, which can be taken almost without limits as the body manages excess. However, retinol, which is well absorbed, can be toxic in excess. There’s often a need in hypothyroidism, so I take one capsule every three days.
7
Micronutrients may improve quality of life
We conducted a study to explore how certain micronutrients, specifically vitamin A, might influence thyroid function and the overall well-being of individuals suffering from hypothyroidism. In this randomized, controlled trial, 104 participants already on levothyroxine and vitamin D were assigned to receive either a mix of micronutrient supplements or a placebo for eight weeks.
Among the micronutrients tested, vitamin A was one of several key components we were curious about. While we found that the group receiving these supplements showed some improvement in insulin resistance and aspects of their quality of life, the specific impact of vitamin A alone on thyroid function was not clearly isolated. We did not observe significant benefits related directly to thyroid hormone levels, which suggests that additional research is necessary to determine the precise role vitamin A plays in managing hypothyroidism.
In conclusion, while our findings hint at the potential benefits of a broader approach to micronutrient supplementation, they leave room for future investigations to clarify the specific contributions of vitamin A and its interactions with other nutrients.
Among the micronutrients tested, vitamin A was one of several key components we were curious about. While we found that the group receiving these supplements showed some improvement in insulin resistance and aspects of their quality of life, the specific impact of vitamin A alone on thyroid function was not clearly isolated. We did not observe significant benefits related directly to thyroid hormone levels, which suggests that additional research is necessary to determine the precise role vitamin A plays in managing hypothyroidism.
In conclusion, while our findings hint at the potential benefits of a broader approach to micronutrient supplementation, they leave room for future investigations to clarify the specific contributions of vitamin A and its interactions with other nutrients.
7
We explored the relationship between vitamin A levels, the atherogenic index of plasma (AIP), and subclinical hypothyroidism among a sizeable group of 3,530 Chinese adults. Through our cross-sectional analysis, we aimed to understand how vitamin A deficiency might influence the risk of developing subclinical hypothyroidism, particularly focusing on different age and sex groups.
Our findings revealed that individuals with sufficient vitamin A levels exhibited a positive association between AIP and total triiodothyronine (TT3) levels. Interestingly, those with severe vitamin A deficiency demonstrated heightened AIP levels linked to increased free triiodothyronine (fT3) and TT3 levels, alongside lower free thyroxine (fT4) levels. More significantly, severe deficiency appeared to escalate the risk of subclinical hypothyroidism when associated with higher AIP—especially in women and older adults.
However, this analysis does not suggest vitamin A as a treatment for hypothyroidism. Instead, it highlights the potential risk related to vitamin A deficiency in connection with subclinical hypothyroidism. Ultimately, while we observed important associations, the study underscored a crucial point: maintaining adequate levels of vitamin A may be vital for overall thyroid health, particularly for vulnerable groups like women and the elderly.
Our findings revealed that individuals with sufficient vitamin A levels exhibited a positive association between AIP and total triiodothyronine (TT3) levels. Interestingly, those with severe vitamin A deficiency demonstrated heightened AIP levels linked to increased free triiodothyronine (fT3) and TT3 levels, alongside lower free thyroxine (fT4) levels. More significantly, severe deficiency appeared to escalate the risk of subclinical hypothyroidism when associated with higher AIP—especially in women and older adults.
However, this analysis does not suggest vitamin A as a treatment for hypothyroidism. Instead, it highlights the potential risk related to vitamin A deficiency in connection with subclinical hypothyroidism. Ultimately, while we observed important associations, the study underscored a crucial point: maintaining adequate levels of vitamin A may be vital for overall thyroid health, particularly for vulnerable groups like women and the elderly.
9
We conducted a thorough investigation into how vitamin A supplementation might impact thyroid function, particularly focusing on women who are premenopausal and have varying body weights. Our study was a robust, four-month randomized controlled trial involving 84 healthy women aged 17 to 50. Among them, 56 women were classified as obese, while 28 fell into the nonobese category.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.
Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.
Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.
8
Vitamin A supports thyroid function
We explored the relationship between vitamin A deficiency (VAD) and hypothyroidism, particularly how these deficiencies impact the pituitary-thyroid axis in the body. Our understanding comes from various studies, including those involving children in Africa, where VAD combined with iodine deficiency disorders (IDD) often leads to unique hormonal responses.
In children suffering from both VAD and IDD, we observed that higher levels of thyroid-stimulating hormone (TSH) may actually help in preventing hypothyroidism, despite existing conditions. Interestingly, research in rats showed that moderate VAD alone did not significantly affect the pituitary-thyroid axis. However, when VAD accompanies iodine deficiency, it can lead to more serious cases of primary hypothyroidism than iodine deficiency on its own.
When it comes to treatment, we noted that high doses of vitamin A could correct thyroid dysfunction caused by iodine deficiency. Therefore, while vitamin A does play a role, it doesn't diminish the effectiveness of iodine repletion. Our findings suggest that vitamin A supplementation can help manage thyroid stimulation, especially in individuals affected by both deficiencies.
Thus, we can conclude that while vitamin A isn’t a standalone solution for hypothyroidism, it certainly plays a supportive role in improving treatment outcomes when iodine levels are restored.
In children suffering from both VAD and IDD, we observed that higher levels of thyroid-stimulating hormone (TSH) may actually help in preventing hypothyroidism, despite existing conditions. Interestingly, research in rats showed that moderate VAD alone did not significantly affect the pituitary-thyroid axis. However, when VAD accompanies iodine deficiency, it can lead to more serious cases of primary hypothyroidism than iodine deficiency on its own.
When it comes to treatment, we noted that high doses of vitamin A could correct thyroid dysfunction caused by iodine deficiency. Therefore, while vitamin A does play a role, it doesn't diminish the effectiveness of iodine repletion. Our findings suggest that vitamin A supplementation can help manage thyroid stimulation, especially in individuals affected by both deficiencies.
Thus, we can conclude that while vitamin A isn’t a standalone solution for hypothyroidism, it certainly plays a supportive role in improving treatment outcomes when iodine levels are restored.
8
Vitamin A may positively influence thyroid
We investigated how vitamin A, along with zinc and magnesium, affects those with hypothyroidism. In a rigorous trial, 86 participants received either the supplements or a placebo for 10 weeks.
Our results revealed that those taking the supplements experienced a notable increase in thyroid hormone (FT4) levels and improvements in inflammatory markers. However, overall changes in thyroid function measures were limited.
This suggests that while vitamin A and co-supplements may play a role, more research is likely needed to fully understand their impact on thyroid health.
Our results revealed that those taking the supplements experienced a notable increase in thyroid hormone (FT4) levels and improvements in inflammatory markers. However, overall changes in thyroid function measures were limited.
This suggests that while vitamin A and co-supplements may play a role, more research is likely needed to fully understand their impact on thyroid health.
References
- Nikkhah M, Vafa M, Abiri B, Golgiri F, Sarbakhsh P, et al. The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial. Med J Islam Repub Iran. 2024;38:133. 10.47176/mjiri.38.133
- Mao G, Chen M, Huang L, Mo Z, Su D, et al. Differences in Vitamin A Levels and Their Association with the Atherogenic Index of Plasma and Subclinical Hypothyroidism in Adults: A Cross-Sectional Analysis in China. Nutrients. 2024;16. 10.3390/nu16162613
- Elfimova AE, Tipisova EV, Bichkaeva FA, Molodovskaya IN, Vlasova OS, et al. [Relationship of vitamin A and thyroid function in Arctic residents]. Vopr Pitan. 2023;92:66. 10.33029/0042-8833-2023-92-4-66-73
- Ma B, Yang P, Gao J, Du L, Sheng C, et al. Relationship of Vitamin A and Thyroid Function in Individuals With Obesity and After Laparoscopic Sleeve Gastrectomy. Front Nutr. 2022;9:824193. 10.3389/fnut.2022.824193
- Farhangi MA, Keshavarz SA, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi AA. The effect of vitamin A supplementation on thyroid function in premenopausal women. J Am Coll Nutr. 2012;31:268.
- Senatore V, Cione E, Gnoni A, Genchi G. Retinoylation reactions are inversely related to the cardiolipin level in testes mitochondria from hypothyroid rats. J Bioenerg Biomembr. 2010;42:321. 10.1007/s10863-010-9293-8
- Schwarz BC, Sallmutter T, Nell B. Keratoconjunctivitis sicca attributable to parasympathetic facial nerve dysfunction associated with hypothyroidism in a horse. J Am Vet Med Assoc. 2008;233:1761. 10.2460/javma.233.11.1761
- Zimmermann MB. Interactions of vitamin A and iodine deficiencies: effects on the pituitary-thyroid axis. Int J Vitam Nutr Res. 2007;77:236.
- Biebinger R, Arnold M, Langhans W, Hurrell RF, Zimmermann MB. Vitamin A repletion in rats with concurrent vitamin A and iodine deficiency affects pituitary TSHbeta gene expression and reduces thyroid hyperstimulation and thyroid size. J Nutr. 2007;137:573.
- Enderlin V, Vallortigara J, Alfos S, Féart C, Pallet V, et al. Retinoic acid reverses the PTU related decrease in neurogranin level in mice brain. J Physiol Biochem. 2004;60:191.
- Rabbani E, Golgiri F, Janani L, Moradi N, Fallah S, et al. Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism. Biol Trace Elem Res. 2021;199:4074. 10.1007/s12011-020-02548-3
- Zimmermann MB, Wegmüller R, Zeder C, Chaouki N, Torresani T. The effects of vitamin A deficiency and vitamin A supplementation on thyroid function in goitrous children. J Clin Endocrinol Metab. 2004;89:5441.
