' 
![]()
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Researches
7
USERS' SCORE
Good
Based on 6 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl and pyridoxal-5-phosphate)
50 mg
2,941%
Top Medical Research Studies
7
Pyridoxine improves skin hydration
Pyridoxine stimulates filaggrin production in human epidermal keratinocytes.
Relevant for skin health research
We explored the effects of pyridoxine, a form of vitamin B6, on skin health, focusing particularly on its potential benefits for those struggling with acne. Our research indicates that pyridoxine plays a significant role in maintaining the function of the epidermis, the outermost layer of our skin.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Read More
Most Useful Reviews
8.3
Skin condition improved
I bought this brand with B12 and feel it has improved my skin condition; I no longer suffer from acne. The effects are noticeable, and I usually take them after breakfast.
Read More
7.5
Helpful for acne
I purchased this mainly to counteract PMS. B6 is known to help with acne and skin issues during menstruation. I’m hopeful about its effects, and the stylish bottle makes it appealing to have on display.
Read More
8.8
Acne improved
I used this primarily for Meniere's and chronic illness. Although my strength has returned, I experienced adult acne. Thankfully, prior breakouts on my chin cleared up completely when I took this with B2. Thank you!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Researches
7
7
Pyridoxine improves skin hydration
Pyridoxine stimulates filaggrin production in human epidermal keratinocytes.
Relevant for skin health research
We explored the effects of pyridoxine, a form of vitamin B6, on skin health, focusing particularly on its potential benefits for those struggling with acne. Our research indicates that pyridoxine plays a significant role in maintaining the function of the epidermis, the outermost layer of our skin.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.5
8.8
Acne improved
I used this primarily for Meniere's and chronic illness. Although my strength has returned, I experienced adult acne. Thankfully, prior breakouts on my chin cleared up completely when I took this with B2. Thank you!
8.8
Reduces acne
I take this to improve my facial acne.
8.8
Good for acne
My son with ADHD uses this as a nerve vitamin, and I've found it beneficial for his problematic skin, especially acne.
8.8
Treats acne
I included this in my acne treatment regimen, and it has helped me significantly.
8.3
Skin condition improved
I bought this brand with B12 and feel it has improved my skin condition; I no longer suffer from acne. The effects are noticeable, and I usually take them after breakfast.
