Last update
5/19/2026
Reviewed By
Infographics
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%
Total Omega-3s♢
690 mg
†
EPA (Eicosapentaenoic Acid)
330 mg
†
DHA (Docosahexaenoic Acid)
220 mg
†
Top Medical Research Studies
9
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
8
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
8
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Read More
Most Useful Reviews
9
Clear skin achieved
9 people found this helpful
I’ve been taking this omega-3 daily for half a year, and my acne-prone skin is now clear!
Read More
10
Acne disappeared completely
1 people found this helpful
This excellent fish oil has large capsules, but they’re consumed quickly. My husband and I used two jars during the second wave of the pandemic. Although we faced difficulties, my hair grew rapidly and, most significantly, the acne that troubled me for years has vanished. The results alone are worth the investment. I plan to take these supplements regularly, at least once a year, and I've even encouraged my child to try them. I highly recommend it.
Read More
7
Reduced acne inflammation
I’ve been taking this omega-3 for years at the suggestion of an acne specialist. Consistent use has softened my skin oils, making acne less likely and easing the extraction process. I've also noticed benefits for my immune system. There’s no fishy aftertaste, and it even has a lemon flavour if I burp—a rare occurrence! Quality and health benefits are outstanding!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7
- All Researches
9
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
8
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Read More
8
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
Read More
8
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Read More
8
We aimed to explore the effectiveness of eicosapentaenoic acid (EPA) along with other long-chain polyunsaturated fatty acids (LC-PUFAs) in treating acne and superficial infections caused by the bacteria Propionibacterium acnes and Staphylococcus aureus. In our investigation, we found that these fatty acids exhibited antibacterial properties, with a range of effectiveness against the two types of bacteria.
The study revealed that P. acnes showed more sensitivity to the growth-inhibiting effects of LC-PUFAs compared to S. aureus. Interestingly, while these compounds were capable of stopping P. acnes growth, they were only bactericidal, meaning they could kill S. aureus. Our findings also included the discovery of the antibacterial activity in previously unreported fatty acids such as 15-hydroxyeicosapentaenoic acid (15-OHEPA) and 15-hydroxyeicosatrienoic acid (HETrE).
Additionally, we noted that when S. aureus was exposed to these fatty acids, the bacteria were effectively killed within a short timeframe, specifically between 15 to 30 minutes. Combining these LC-PUFAs with established treatments did not reduce their effectiveness and revealed potential potentiation of action, particularly in combinations with commonly used acne medications like benzoyl peroxide and neomycin.
In conclusion, our observations suggest that eicosapentaenoic acid and other LC-PUFAs may be valuable new options for treating skin infections caused by P. acnes and S. aureus, especially when used alongside conventional therapies. However, further studies are needed to fully understand their potential in clinical settings.
The study revealed that P. acnes showed more sensitivity to the growth-inhibiting effects of LC-PUFAs compared to S. aureus. Interestingly, while these compounds were capable of stopping P. acnes growth, they were only bactericidal, meaning they could kill S. aureus. Our findings also included the discovery of the antibacterial activity in previously unreported fatty acids such as 15-hydroxyeicosapentaenoic acid (15-OHEPA) and 15-hydroxyeicosatrienoic acid (HETrE).
Additionally, we noted that when S. aureus was exposed to these fatty acids, the bacteria were effectively killed within a short timeframe, specifically between 15 to 30 minutes. Combining these LC-PUFAs with established treatments did not reduce their effectiveness and revealed potential potentiation of action, particularly in combinations with commonly used acne medications like benzoyl peroxide and neomycin.
In conclusion, our observations suggest that eicosapentaenoic acid and other LC-PUFAs may be valuable new options for treating skin infections caused by P. acnes and S. aureus, especially when used alongside conventional therapies. However, further studies are needed to fully understand their potential in clinical settings.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Clear skin achieved
9 people found this helpful
I’ve been taking this omega-3 daily for half a year, and my acne-prone skin is now clear!
Read More
10
Acne disappeared completely
1 people found this helpful
This excellent fish oil has large capsules, but they’re consumed quickly. My husband and I used two jars during the second wave of the pandemic. Although we faced difficulties, my hair grew rapidly and, most significantly, the acne that troubled me for years has vanished. The results alone are worth the investment. I plan to take these supplements regularly, at least once a year, and I've even encouraged my child to try them. I highly recommend it.
Read More
7
Reduced acne inflammation
I’ve been taking this omega-3 for years at the suggestion of an acne specialist. Consistent use has softened my skin oils, making acne less likely and easing the extraction process. I've also noticed benefits for my immune system. There’s no fishy aftertaste, and it even has a lemon flavour if I burp—a rare occurrence! Quality and health benefits are outstanding!
Read More
Frequently Asked Questions
9
Clear skin achieved
9 people found this helpful
I’ve been taking this omega-3 daily for half a year, and my acne-prone skin is now clear!
10
Acne disappeared completely
1 people found this helpful
This excellent fish oil has large capsules, but they’re consumed quickly. My husband and I used two jars during the second wave of the pandemic. Although we faced difficulties, my hair grew rapidly and, most significantly, the acne that troubled me for years has vanished. The results alone are worth the investment. I plan to take these supplements regularly, at least once a year, and I've even encouraged my child to try them. I highly recommend it.
7
Reduced acne inflammation
I’ve been taking this omega-3 for years at the suggestion of an acne specialist. Consistent use has softened my skin oils, making acne less likely and easing the extraction process. I've also noticed benefits for my immune system. There’s no fishy aftertaste, and it even has a lemon flavour if I burp—a rare occurrence! Quality and health benefits are outstanding!
9
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
8
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
7
Omega-3s benefit inflammatory skin conditions
We examined a variety of studies on omega-3 fatty acids (O3FAs) and their impact on skin conditions, including acne. The review encompassed 38 studies, highlighting benefits such as a reduction in inflammatory lesions and side effects from other acne treatments like isotretinoin.
Although the findings suggest potential advantages, specifically for inflammatory skin issues, O3FAs are best viewed as a supplemental option rather than a standalone solution for acne. Overall, their low cost and safety make them a viable addition to treatment strategies for those seeking to improve their skin health.
Although the findings suggest potential advantages, specifically for inflammatory skin issues, O3FAs are best viewed as a supplemental option rather than a standalone solution for acne. Overall, their low cost and safety make them a viable addition to treatment strategies for those seeking to improve their skin health.
8
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
4
We evaluated the effects of omega-3 fish oil on inflammatory acne in a group of 13 individuals over 12 weeks. Each participant continued their regular acne treatments while taking three grams of fish oil daily.
While the overall results showed no significant changes in acne severity scores or inflammatory lesion counts, we observed varied individual responses. Eight participants showed improvement, particularly those with moderate to severe acne, while four experienced worsening conditions.
These findings suggest that omega-3 supplementation may be beneficial for some, but further research is necessary to confirm its effectiveness.
While the overall results showed no significant changes in acne severity scores or inflammatory lesion counts, we observed varied individual responses. Eight participants showed improvement, particularly those with moderate to severe acne, while four experienced worsening conditions.
These findings suggest that omega-3 supplementation may be beneficial for some, but further research is necessary to confirm its effectiveness.
References
- Zhang L, Li Y, Pu Y, Dang T, Shi Q, et al. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr. 2025;64:130. 10.1007/s00394-025-03647-4
- Guertler A, Neu K, Lill D, Clanner-Engelshofen B, French LE, et al. Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study. J Cosmet Dermatol. 2024;23:3295. 10.1111/jocd.16434
- Huang Y, Liu F, Lai J, Jiang S, Tan X, et al. The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris. J Dermatolog Treat. 2024;35:2299107. 10.1080/09546634.2023.2299107
- Zainab Z, Malik NA, Obaid S, Malik S, Aftab K, et al. Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris. J Ayub Med Coll Abbottabad. 2021;33:60. PubMed
- Thomsen BJ, Chow EY, Sapijaszko MJ. The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. J Cutan Med Surg. 2020;24:481. 10.1177/1203475420929925
- Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017;128-129:1. 10.1016/j.prostaglandins.2016.12.001
- Jung JY, Kwon HH, Hong JS, Yoon JY, Park MS, et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014;94:521. 10.2340/00015555-1802
- Khayef G, Young J, Burns-Whitmore B, Spalding T. Effects of fish oil supplementation on inflammatory acne. Lipids Health Dis. 2012;11:165. 10.1186/1476-511X-11-165
- Kim BR, Kim G, Jin SP, Choi CW, Kim J, et al. The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study. Br J Dermatol. 2025. 10.1093/bjd/ljaf052
- Desbois AP, Lawlor KC. Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Mar Drugs. 2013;11:4544. 10.3390/md11114544
- Rubin MG, Kim K, Logan AC. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids Health Dis. 2008;7:36. 10.1186/1476-511X-7-36
