Omega-3 improves acne severityExploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study.
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.
We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
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Docosahexaenoic acid reduces acne riskThe causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study.
We investigated the relationship between docosahexaenoic acid (DHA), a type of polyunsaturated fatty acid (PUFA), and the occurrence of acne. Using a method called Mendelian randomization, we looked at how genetic variations associated with DHA might influence acne development in large groups of participants, including over 115,000 individuals from the UK and nearly 364,000 of Finnish ancestry.
Our findings revealed that higher levels of DHA are actually linked to a lower risk of developing acne. Specifically, we found that a significant increase in DHA levels or its proportion compared to total fatty acids corresponded with a reduced likelihood of acne. In contrast, higher levels of linoleic acid (LA), another type of PUFA, were associated with an increased acne risk.
This suggests that balancing our intake of these fatty acids might be important for skin health. Notably, the results pointed towards a genetic connection involving the FADS1 gene, which appears to play a role in how these fatty acids affect our skin.
In conclusion, increasing DHA could be beneficial in protecting against acne, while excessive linoleic acid might have the opposite effect. Overall, our study highlights the importance of these fatty acids in understanding acne risk better.
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Impact of fatty acids on acneExploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.
Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.
More diverse research is needed to fully understand these effects across different groups.
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Omega-3 effects on acne studiedThe adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris.
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
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Omega-3 improves acne symptomsEffect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial.
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.
The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
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