Last update
5/2/2026

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%
Total Omega-3s♦
500 mg
EPA (Eicosapentaenoic Acid)
240 mg
DHA (Docosahexaenoic Acid)
160 mg
Evening Primrose Oil
800 mg
Gamma-Linolenic Acid (Omega-6)
76 mg
📅 Last updated:

Top Medical Research Studies

We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.

We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
8
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.

Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.

More diverse research is needed to fully understand these effects across different groups.
Read More
8
Omega-3 improves acne symptoms
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.

The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Read More

Most Useful Reviews

9
Miracle worker for acne
35 people found this helpful
Five Stars. Cleared my cystic hormonal acne (+Borage oil 1300mg) in 2 weeks. It's a miracle worker.
Read More
10
Drastic acne improvement
14 people found this helpful
It works!!! This is my second time ordering these omega woman pills! I suffered from hormonal cystic acne and read about fish oil's inflammatory properties. I tried everything to get my acne under control and, although there was no immediate change, I noticed a drastic improvement towards the end of April; no more big swollen bumps! It’s now May and I have smooth, acne-free skin. I’m so glad I tried this!
Read More
10
Cured hormonal acne
3 people found this helpful
Five Stars. This was the cure for my hormonal acne and mood swings!
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7
  • All Researches
We observed that omega-3 fatty acids, particularly EPA and DHA, could be beneficial for patients struggling with acne. Over 16 weeks, 60 participants followed a Mediterranean diet and received algae-derived omega-3 supplements.

We found that most patients initially had low omega-3 levels, but these rose significantly during the study. Acne severity showed notable improvement, especially in those achieving optimal omega-3 levels. Though four patients reported worsened appearance, overall quality of life improved for the majority.
Read More
8
We systematically reviewed studies on how omega-3 and omega-6 fatty acids affect acne. Our findings indicate that omega-3s may help reduce acne, while some omega-6s could exacerbate it.

Additionally, our genetic analysis explored how these fatty acids interact with key enzymes related to acne. However, it's important to note that the study's population was limited primarily to Europeans, which may not reflect the broader community.

More diverse research is needed to fully understand these effects across different groups.
Read More
We investigated whether omega-3 fatty acids could help manage acne by influencing gut bacteria. Over 12 weeks, untreated acne patients were divided into two groups: one received omega-3 supplements while the other didn’t. We also tested in rats with an acne model. The findings indicated that omega-3 increased gut bacteria diversity and enhanced beneficial bacteria linked to anti-inflammatory effects. However, despite these promising changes, we did not observe a significant overall impact on acne improvement in patients.
Read More
8
Omega-3 improves acne symptoms
We examined how omega-3 fatty acids and gamma-linolenic acid could help with acne in a well-structured 10-week study. Involving 45 participants with mild to moderate acne, we compared those taking omega-3, those taking gamma-linolenic acid, and a control group.

The findings were promising: both omega-3 and gamma-linolenic acid showed a significant reduction in both inflammatory and non-inflammatory acne lesions. Participants also reported noticeable improvements in their skin. Importantly, no severe side effects were noted, indicating these supplements might be a beneficial addition to existing acne treatments.
Read More
8
Eicosapentaenoic acid shows promise
We aimed to explore the effectiveness of eicosapentaenoic acid (EPA) along with other long-chain polyunsaturated fatty acids (LC-PUFAs) in treating acne and superficial infections caused by the bacteria Propionibacterium acnes and Staphylococcus aureus. In our investigation, we found that these fatty acids exhibited antibacterial properties, with a range of effectiveness against the two types of bacteria.

The study revealed that P. acnes showed more sensitivity to the growth-inhibiting effects of LC-PUFAs compared to S. aureus. Interestingly, while these compounds were capable of stopping P. acnes growth, they were only bactericidal, meaning they could kill S. aureus. Our findings also included the discovery of the antibacterial activity in previously unreported fatty acids such as 15-hydroxyeicosapentaenoic acid (15-OHEPA) and 15-hydroxyeicosatrienoic acid (HETrE).

Additionally, we noted that when S. aureus was exposed to these fatty acids, the bacteria were effectively killed within a short timeframe, specifically between 15 to 30 minutes. Combining these LC-PUFAs with established treatments did not reduce their effectiveness and revealed potential potentiation of action, particularly in combinations with commonly used acne medications like benzoyl peroxide and neomycin.

In conclusion, our observations suggest that eicosapentaenoic acid and other LC-PUFAs may be valuable new options for treating skin infections caused by P. acnes and S. aureus, especially when used alongside conventional therapies. However, further studies are needed to fully understand their potential in clinical settings.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Miracle worker for acne
35 people found this helpful
Five Stars. Cleared my cystic hormonal acne (+Borage oil 1300mg) in 2 weeks. It's a miracle worker.
Read More
10
Drastic acne improvement
14 people found this helpful
It works!!! This is my second time ordering these omega woman pills! I suffered from hormonal cystic acne and read about fish oil's inflammatory properties. I tried everything to get my acne under control and, although there was no immediate change, I noticed a drastic improvement towards the end of April; no more big swollen bumps! It’s now May and I have smooth, acne-free skin. I’m so glad I tried this!
Read More
10
Cured hormonal acne
3 people found this helpful
Five Stars. This was the cure for my hormonal acne and mood swings!
Read More
9
Stopped adult acne
3 people found this helpful
Helped me with my acne. Somehow after taking this, my adult acne stopped, and I really enjoy not dealing with it anymore after battling for a few years!
Read More
7.5
Radiant skin throughout cycle
14 people found this helpful
I hesitate to use the word "miracle," but these really are something. I have suffered from hormonal cystic acne for years. After taking this for 1.5 cycles, my skin is radiant throughout my cycle. I do wonder about the safety of long-term usage, but I never want to quit getting these results. I highly recommend discussing this with a doctor if you have hormonal acne.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Zhang L, Li Y, Pu Y, Dang T, Shi Q, et al. Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne. Eur J Nutr. 2025;64:130. 10.1007/s00394-025-03647-4
  2. Guertler A, Neu K, Lill D, Clanner-Engelshofen B, French LE, et al. Exploring the potential of omega-3 fatty acids in acne patients: A prospective intervention study. J Cosmet Dermatol. 2024;23:3295. 10.1111/jocd.16434
  3. Huang Y, Liu F, Lai J, Jiang S, Tan X, et al. The adjuvant treatment role of ω-3 fatty acids by regulating gut microbiota positively in the acne vulgaris. J Dermatolog Treat. 2024;35:2299107. 10.1080/09546634.2023.2299107
  4. Zainab Z, Malik NA, Obaid S, Malik S, Aftab K, et al. Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris. J Ayub Med Coll Abbottabad. 2021;33:60. PubMed
  5. Thomsen BJ, Chow EY, Sapijaszko MJ. The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. J Cutan Med Surg. 2020;24:481. 10.1177/1203475420929925
  6. Aslan İ, Özcan F, Karaarslan T, Kıraç E, Aslan M. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. Prostaglandins Other Lipid Mediat. 2017;128-129:1. 10.1016/j.prostaglandins.2016.12.001
  7. Jung JY, Kwon HH, Hong JS, Yoon JY, Park MS, et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014;94:521. 10.2340/00015555-1802
  8. Khayef G, Young J, Burns-Whitmore B, Spalding T. Effects of fish oil supplementation on inflammatory acne. Lipids Health Dis. 2012;11:165. 10.1186/1476-511X-11-165
  9. Kim BR, Kim G, Jin SP, Choi CW, Kim J, et al. The causal association between polyunsaturated fatty acids and acne: A two-sample Mendelian randomization study. Br J Dermatol. 2025. 10.1093/bjd/ljaf052
  10. Desbois AP, Lawlor KC. Antibacterial activity of long-chain polyunsaturated fatty acids against Propionibacterium acnes and Staphylococcus aureus. Mar Drugs. 2013;11:4544. 10.3390/md11114544
  11. Rubin MG, Kim K, Logan AC. Acne vulgaris, mental health and omega-3 fatty acids: a report of cases. Lipids Health Dis. 2008;7:36. 10.1186/1476-511X-7-36
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