Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 36 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%
Saturated Fat
0 g
0%
Trans Fat
0 g
â€
Vitamin D3 (cholecalciferol)
25 mcg (1000 IU)
125%
Total Omega-3s♦
1280 mg
â€
EPA (Eicosapentaenoic Acid)
650 mg
â€
DHA (Docosahexaenoic Acid)
450 mg
â€
Top Medical Research Studies
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
9
We explored the potential benefits of vitamin D3 supplementation for people suffering from migraines. In a carefully designed study, 80 individuals with episodic migraines participated in a 12-week trial where they were randomly assigned to receive either 2000 IU (50 μg) of vitamin D3 daily or a placebo.
Throughout the study, we closely monitored headache characteristics using diaries and measured various serum inflammatory markers before and after the trial. Our findings showed that those taking vitamin D3 experienced significant improvements. They reported fewer headache days each month, shorter headache durations, and less severe pain overall when compared to the placebo group.
Interestingly, while the levels of some inflammatory markers didn't change much, we did notice a striking reduction in a certain enzyme linked to inflammation in the vitamin D3 group. Additionally, there was a trend toward lower levels of another inflammation marker, suggesting that vitamin D3 might offer a protective effect against neuro-inflammation in migraine sufferers.
In essence, our study indicates that vitamin D3 could be a promising supplemental treatment to help improve the quality of life for those battling episodic migraines.
Throughout the study, we closely monitored headache characteristics using diaries and measured various serum inflammatory markers before and after the trial. Our findings showed that those taking vitamin D3 experienced significant improvements. They reported fewer headache days each month, shorter headache durations, and less severe pain overall when compared to the placebo group.
Interestingly, while the levels of some inflammatory markers didn't change much, we did notice a striking reduction in a certain enzyme linked to inflammation in the vitamin D3 group. Additionally, there was a trend toward lower levels of another inflammation marker, suggesting that vitamin D3 might offer a protective effect against neuro-inflammation in migraine sufferers.
In essence, our study indicates that vitamin D3 could be a promising supplemental treatment to help improve the quality of life for those battling episodic migraines.
Read More
Most Useful Reviews
7.5
Dissipating migraines
2 people found this helpful
These are easy to swallow with no fishy burps, unlike other omega 3 supplements. I'm using them to increase my EPA and DHA intake, as I don't particularly like fish. I've noticed that my migraines have begun to dissipate. The dietitians I work with highly recommend this product for supplementation when natural sources are unavailable.
Read More
7.5
Reduced migraines
The best omega; I take it all the time. It’s excellent for women. Since I started, the frequency of my migraines has decreased, and my skin has improved.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 36 Researches
7.2
- All Researches
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
9.5
We conducted a thorough investigation into the effectiveness of simvastatin paired with vitamin D3 for preventing migraines in adults with episodic migraine. Our study was a well-structured randomized, double-blind, placebo-controlled trial involving 57 participants over a span of 24 weeks.
Participants were divided into two groups: one receiving simvastatin and vitamin D3, while the other received placebos. Throughout the trial, we observed that those taking the combination of simvastatin and vitamin D3 experienced a significant reduction in the number of migraine days when compared to those on placebos. Specifically, during the first 12 weeks, participants on the active regimen reported a decrease of 8.0 migraine days, whereas those on placebos noted an increase of 1.0 migraine days.
By the end of the 24-week period, an impressive 29% of participants taking the medication reported a 50% or more reduction in their migraine days. In contrast, only 3% of those taking the placebo experienced similar relief. Interestingly, we found that the occurrence of adverse events was similar in both groups, indicating that the combination therapy was generally well-tolerated.
Our findings showcase the potential benefits of using simvastatin alongside vitamin D3 as an effective strategy for managing migraines, while also addressing some underlying health risks associated with migraines, such as vascular issues.
Participants were divided into two groups: one receiving simvastatin and vitamin D3, while the other received placebos. Throughout the trial, we observed that those taking the combination of simvastatin and vitamin D3 experienced a significant reduction in the number of migraine days when compared to those on placebos. Specifically, during the first 12 weeks, participants on the active regimen reported a decrease of 8.0 migraine days, whereas those on placebos noted an increase of 1.0 migraine days.
By the end of the 24-week period, an impressive 29% of participants taking the medication reported a 50% or more reduction in their migraine days. In contrast, only 3% of those taking the placebo experienced similar relief. Interestingly, we found that the occurrence of adverse events was similar in both groups, indicating that the combination therapy was generally well-tolerated.
Our findings showcase the potential benefits of using simvastatin alongside vitamin D3 as an effective strategy for managing migraines, while also addressing some underlying health risks associated with migraines, such as vascular issues.
Read More
9
We conducted a study to evaluate how vitamin D supplementation affects migraine relief in children aged 5 to 14 who are also taking topiramate, a common migraine medication. Our trial involved a double-blind design, where participants were randomly assigned to either receive vitamin D or a placebo alongside their topiramate treatment for four months.
The results were promising. Children who took vitamin D showed a significant decrease in the monthly frequency of their headaches and a lowered disability score related to migraines compared to those who received the placebo. Notably, about 76% of the kids in the vitamin D group reported a good response to the treatment, while only 53.5% in the placebo group did.
We also found that the side effects of both treatments were minimal and similar, indicating that vitamin D supplementation is generally well-tolerated. These findings suggest that adding vitamin D to topiramate can be an effective and safe strategy for managing migraines in young patients.
The results were promising. Children who took vitamin D showed a significant decrease in the monthly frequency of their headaches and a lowered disability score related to migraines compared to those who received the placebo. Notably, about 76% of the kids in the vitamin D group reported a good response to the treatment, while only 53.5% in the placebo group did.
We also found that the side effects of both treatments were minimal and similar, indicating that vitamin D supplementation is generally well-tolerated. These findings suggest that adding vitamin D to topiramate can be an effective and safe strategy for managing migraines in young patients.
Read More
9
In our exploration of pediatric migraine prevention, we conducted a clinical trial comparing the effects of topiramate alone and in combination with vitamin D3. We targeted children aged 5 to 15 years, randomly assigning them to one of the two treatment groups over two months.
Our findings indicated that both topiramate and the combination therapy were effective in reducing the frequency, severity, and duration of migraine episodes. However, we discovered that adding vitamin D3 significantly improved results. Children receiving both treatments experienced fewer migraines and a lower disability score compared to the topiramate-only group.
We also noted that 75.9% of the children taking the combination reported a good response to treatment, compared to 60.7% in the topiramate group. Side effects were mild and similar for both treatments, suggesting that the addition of vitamin D3 is a safe option worth considering for migraine prevention in children.
Our findings indicated that both topiramate and the combination therapy were effective in reducing the frequency, severity, and duration of migraine episodes. However, we discovered that adding vitamin D3 significantly improved results. Children receiving both treatments experienced fewer migraines and a lower disability score compared to the topiramate-only group.
We also noted that 75.9% of the children taking the combination reported a good response to treatment, compared to 60.7% in the topiramate group. Side effects were mild and similar for both treatments, suggesting that the addition of vitamin D3 is a safe option worth considering for migraine prevention in children.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Dissipating migraines
2 people found this helpful
These are easy to swallow with no fishy burps, unlike other omega 3 supplements. I'm using them to increase my EPA and DHA intake, as I don't particularly like fish. I've noticed that my migraines have begun to dissipate. The dietitians I work with highly recommend this product for supplementation when natural sources are unavailable.
Read More
7.5
Reduced migraines
The best omega; I take it all the time. It’s excellent for women. Since I started, the frequency of my migraines has decreased, and my skin has improved.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
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