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NOW Supplements Acidophilus
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*

Top Medical Research Studies

9
Probiotics reduce anxiety in rats
[Antioxidant and anxiolytic effect of and under conditions of normobaric hypoxia with hypercapnia].
Highly relevant to mental health.
We investigated whether administering Lactobacillus acidophilus could alleviate anxiety and oxidative stress in rats, particularly during challenging conditions like hypoxia.

In our study, rats were divided into groups and given probiotics over 30 days. Those treated with Lactobacillus showed less oxidative damage and anxiety than the untreated hypoxia group.

Overall, we found that Lactobacillus acidophilus contributes to reducing anxiety levels, potentially offering an interesting avenue for mental health treatment.
Read More
7
Probiotics may aid depression treatment
Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial.
Relevance score indicates moderate significance.
We explored how probiotics, particularly Lactobacillus acidophilus, might impact depression in patients diagnosed with major depressive disorder (MDD). In a double-blind, placebo-controlled trial involving 40 participants, we found that after eight weeks of probiotic treatment, symptoms of depression improved along with certain metabolic markers.

However, it's important to note that while there were positive changes, probiotics did not significantly affect glucose levels or lipid profiles. Overall, our findings suggest that probiotics might be a helpful addition to depression treatment strategies.
Read More
8
Lactobacillus acidophilus and depression
Suppressive Effects of on Depression through Regulating the Gut Microbiota and Metabolites in C57BL/6J Mice Induced by Ampicillin.
Moderate relevance for mental health
We investigated the effects of lactobacillus acidophilus strains on depression in mice. The study involved administering different dosages of probiotics to mice made depressed by ampicillin.

Behavioral tests revealed that the mice given probiotics showed signs of recovery from their depressive symptoms. The treatment also impacted their gut microbiota composition, favorably altering the levels of certain beneficial bacteria.

However, while the results are promising, more research is needed to confirm the long-term effectiveness of these probiotics on depression in humans.
Read More

Most Useful Reviews

8.8
Improved mental health
Probiotics are beneficial microorganisms that help maintain gut health and improve digestion. They support nutrient absorption and strengthen the immune system, which can reduce the risk of infections. Importantly, probiotics influence mental health; they can alleviate symptoms of anxiety and depression. By enhancing gut flora balance, probiotics positively impact mood and cognitive function. Incorporating quality probiotic-rich foods and supplements into my diet has noticeably benefitted my mental well-being, making me feel healthier overall.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
  • All Researches
9
Probiotics may enhance mood, sleep
Novel Multi-Strain E3 Probiotic Formulation Improved Mental Health Symptoms and Sleep Quality in Hong Kong Chinese.
High relevance for mental health
We investigated the impact of a novel multi-strain E3 probiotic on mental health, sleep quality, and gut microbiome in 68 participants from Hong Kong. After an 8-week treatment, significant improvements were reported in depressive symptoms, anxiety, and sleep quality. Participants showed decreased scores on standardized surveys, with notable changes in gut microbiome composition linked to these improvements. Our findings highlight the potential benefits of probiotics for those experiencing mood disorders and sleep issues, suggesting that these strategies may effectively enhance mental well-being.
Read More
9
Probiotics reduce anxiety in rats
[Antioxidant and anxiolytic effect of and under conditions of normobaric hypoxia with hypercapnia].
Highly relevant to mental health.
We investigated whether administering Lactobacillus acidophilus could alleviate anxiety and oxidative stress in rats, particularly during challenging conditions like hypoxia.

In our study, rats were divided into groups and given probiotics over 30 days. Those treated with Lactobacillus showed less oxidative damage and anxiety than the untreated hypoxia group.

Overall, we found that Lactobacillus acidophilus contributes to reducing anxiety levels, potentially offering an interesting avenue for mental health treatment.
Read More
8
Probiotic yogurt alleviates depression
Effects of a Novel Fortified Dairy Product on the Psychological Status and Sleep Quality of Patients with Polycystic Ovary Syndrome: A Double-Blind Randomized Controlled Trial.
High relevance for mental health
We explored the effects of fortified yogurt on women with polycystic ovary syndrome (PCOS) over an 8-week period. In this randomized, double-blind study, one group enjoyed yogurt enriched with probiotics, vitamin E, and vitamin D, while the other had a standard yogurt placebo.

Participants in the yogurt group showed significant improvement in depression levels compared to the placebo group, though no gains were noted in sleep quality. This suggests that incorporating probiotics in dietary interventions may help manage depression in PCOS patients, serving as an alternative for those hesitant to use traditional antidepressants. However, we recognize the need for further research to solidify these findings.
Read More
8
Lactobacillus shows limited anti-depressant effects
A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome.
Moderate relevance to depression treatment.
We examined the effects of a cultured milk drink containing Lactobacillus acidophilus on depression in individuals with irritable bowel syndrome (IBS). Our study involved 110 IBS participants, some experiencing subthreshold depression, who consumed the drink daily for 12 weeks.

While we found significant reductions in depression scores and improvements in quality of life across groups, only the probiotics showed notable increases in serotonin levels. This suggests that while Lactobacillus might provide some benefits, it may not be a singular solution for depression in IBS.
Read More
8
Lactobacillus acidophilus and depression
Suppressive Effects of on Depression through Regulating the Gut Microbiota and Metabolites in C57BL/6J Mice Induced by Ampicillin.
Moderate relevance for mental health
We investigated the effects of lactobacillus acidophilus strains on depression in mice. The study involved administering different dosages of probiotics to mice made depressed by ampicillin.

Behavioral tests revealed that the mice given probiotics showed signs of recovery from their depressive symptoms. The treatment also impacted their gut microbiota composition, favorably altering the levels of certain beneficial bacteria.

However, while the results are promising, more research is needed to confirm the long-term effectiveness of these probiotics on depression in humans.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Improved mental health
Probiotics are beneficial microorganisms that help maintain gut health and improve digestion. They support nutrient absorption and strengthen the immune system, which can reduce the risk of infections. Importantly, probiotics influence mental health; they can alleviate symptoms of anxiety and depression. By enhancing gut flora balance, probiotics positively impact mood and cognitive function. Incorporating quality probiotic-rich foods and supplements into my diet has noticeably benefitted my mental well-being, making me feel healthier overall.
Read More
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