We explored how the probiotic Bifidobacterium longum 5(1A) can affect pneumonia caused by Klebsiella pneumoniae in mice. Our study showed that this treatment led to a quicker resolution of lung inflammation and significantly reduced the bacterial load, ultimately saving 100% of the mice from death.
This protective effect was linked to the activation of the Toll-like receptor signaling pathway. In particular, B. longum 5(1A) helped balance the body's inflammatory response, promoting a faster recovery in the lungs. Overall, our findings suggest that this probiotic could play a beneficial role in enhancing lung health during infections.
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8
Probiotics reduce pneumonia in children
Prebiotic and probiotic fortified milk in prevention of morbidities among children: community-based, randomized, double-blind, controlled trial.
We explored the role of adding Bifidobacterium lactis and prebiotic oligosaccharides to milk in preventing pneumonia in children aged 1-4 years. In a community-based, randomized controlled trial, children received either control milk or fortified milk over a year.
Our findings revealed a 24% reduction in pneumonia incidence and a 35% decrease in severe acute lower respiratory infections among those receiving the fortified milk. However, while there were positive trends, the overall impact on diarrhea wasn’t significant.
This study highlights the potential benefits of using milk as a delivery system for probiotics in fighting respiratory illnesses in young children.
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8
Probiotics reduce respiratory infections
Role of multi-strain probiotics in preventing severity and frequency of recurrent respiratory tract infections in children.
We explored the potential of probiotics, specifically Lactobacillus acidophilus, in reducing the severity and frequency of respiratory tract infections in children. Conducted at Abbassi Shaheed Hospital, our study analyzed 70 children over six months who received probiotics for two weeks.
Our results showed a significant decline in respiratory symptoms and infections among the participants. Overall, this suggests that probiotics can indeed play a beneficial role in supporting children's respiratory health.
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Most Useful Reviews
9
Effective recovery
2 people found this helpful
An excellent tool! My brother fell seriously ill with pneumonia this winter and had difficulty recovering. After taking this supplement, he began to improve, especially after the antibiotics affected his intestinal microflora. I definitely recommend it! We frequently use dietary supplements from NOW and have never been disappointed.
Read More
7.5
Improved immunity
I initially took this for my mother, who has digestion problems. If you take it for at least a month, you will see good results! The composition is excellent! When I had pneumonia due to covid and took antibiotics, these supplements were very helpful. I had no stomach issues during or after the antibiotics, and my recovery was faster.
We explored how the probiotic Bifidobacterium longum 5(1A) can affect pneumonia caused by Klebsiella pneumoniae in mice. Our study showed that this treatment led to a quicker resolution of lung inflammation and significantly reduced the bacterial load, ultimately saving 100% of the mice from death.
This protective effect was linked to the activation of the Toll-like receptor signaling pathway. In particular, B. longum 5(1A) helped balance the body's inflammatory response, promoting a faster recovery in the lungs. Overall, our findings suggest that this probiotic could play a beneficial role in enhancing lung health during infections.
Read More
9
Symbiotics lower postoperative infections
Perioperative synbiotics administration decreases postoperative infections in patients with colorectal cancer: a randomized, double-blind clinical trial.
We explored how administering symbiotics, which include Lactobacillus acidophilus, impacts infection rates following colorectal surgery. In a randomized trial with 91 patients, those receiving symbiotics experienced a notable drop in infections compared to the placebo group. Specifically, only 2% of patients on symbiotics developed surgical site infections, whereas 21.4% in the control group did. This indicates that perioperative symbiotic treatment could be beneficial during surgical recovery. However, further research is necessary to confirm these findings.
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8
L-C-dots show promise against pneumonia
Synergistic antibacterial effects of carbon dots derived from Lactobacillus acidophilus alone and in combination against carbapenem-resistant Klebsiella pneumoniae.
We examined how carbon dots sourced from Lactobacillus acidophilus might tackle carbapenem-resistant Klebsiella pneumoniae, a tough pneumonia-causing bacteria. Our tests showed that these carbon dots, known as L-C-dots, have strong antibacterial properties and can even work well with regular antibiotics.
Importantly, L-C-dots not only inhibited bacterial growth but also prevented biofilm formation, which is often a barrier to successful treatment. They even helped reduce the expression of specific genes linked to biofilm development.
This research suggests that L-C-dots could be a valuable addition to our arsenal against resistant pneumonia infections.
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8
Probiotics reduce respiratory infections
Role of multi-strain probiotics in preventing severity and frequency of recurrent respiratory tract infections in children.
We explored the potential of probiotics, specifically Lactobacillus acidophilus, in reducing the severity and frequency of respiratory tract infections in children. Conducted at Abbassi Shaheed Hospital, our study analyzed 70 children over six months who received probiotics for two weeks.
Our results showed a significant decline in respiratory symptoms and infections among the participants. Overall, this suggests that probiotics can indeed play a beneficial role in supporting children's respiratory health.
Read More
8
Probiotics reduce pneumonia rates
A four-probiotic preparation for ventilator-associated pneumonia in multi-trauma patients: results of a randomized clinical trial.
We explored the impact of a specific combination of probiotics on preventing ventilator-associated pneumonia (VAP) in critically injured patients on mechanical ventilation. In a randomized, placebo-controlled trial, patients received either a probiotic formula or a placebo during their treatment.
The results were promising; those who received the probiotics showed a lower incidence of VAP and sepsis, along with shorter ICU stays. This suggests that using probiotics might be a helpful strategy for protecting vulnerable patients from these infections while in intensive care.
An excellent tool! My brother fell seriously ill with pneumonia this winter and had difficulty recovering. After taking this supplement, he began to improve, especially after the antibiotics affected his intestinal microflora. I definitely recommend it! We frequently use dietary supplements from NOW and have never been disappointed.
Read More
7.5
Improved immunity
I initially took this for my mother, who has digestion problems. If you take it for at least a month, you will see good results! The composition is excellent! When I had pneumonia due to covid and took antibiotics, these supplements were very helpful. I had no stomach issues during or after the antibiotics, and my recovery was faster.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
Shamkhali L, Mobarez AM, Siadat SD, Pajavand H. Synergistic antibacterial effects of carbon dots derived from Lactobacillus acidophilus alone and in combination against carbapenem-resistant Klebsiella pneumoniae. J Infect Public Health. 2025;18:102724. 10.1016/j.jiph.2025.102724
Khan Laghari I, Nawaz T, Mustafa S, Jamali AA, Fatima S. Role of multi-strain probiotics in preventing severity and frequency of recurrent respiratory tract infections in children. BMC Pediatr. 2023;23:505. 10.1186/s12887-023-04338-x
Saviano A, Potenza A, Siciliano V, Petruzziello C, Tarli C, et al. COVID-19 Pneumonia and Gut Inflammation: The Role of a Mix of Three Probiotic Strains in Reducing Inflammatory Markers and Need for Oxygen Support. J Clin Med. 2022;11. 10.3390/jcm11133758
Tsilika M, Thoma G, Aidoni Z, Tsaousi G, Fotiadis K, et al. A four-probiotic preparation for ventilator-associated pneumonia in multi-trauma patients: results of a randomized clinical trial. Int J Antimicrob Agents. 2022;59:106471. 10.1016/j.ijantimicag.2021.106471
Shoaib A, Xin L, Xin Y. Oral administration of Lactobacillus acidophilus alleviates exacerbations in Pseudomonas aeruginosa and Staphylococcus aureus pulmonary infections. Pak J Pharm Sci. 2019;32:1621. PubMed
Flesch AT, Tonial ST, Contu PC, Damin DC. Perioperative synbiotics administration decreases postoperative infections in patients with colorectal cancer: a randomized, double-blind clinical trial. Rev Col Bras Cir. 2017;44:567. 10.1590/0100-69912017006004
Kotzampassi K, Stavrou G, Damoraki G, Georgitsi M, Basdanis G, et al. A Four-Probiotics Regimen Reduces Postoperative Complications After Colorectal Surgery: A Randomized, Double-Blind, Placebo-Controlled Study. World J Surg. 2015;39:2776. 10.1007/s00268-015-3071-z
Gonchar NV, Kassner LN, Korenev PB, Il'kovich IuM, Mogilina SV, et al. [Probiotics as an items of increasing the effectiveness of treatment of community-acquired pneumonia in adolescents]. Eksp Klin Gastroenterol. 2011. PubMed
Río ME, Zago Beatriz L, Garcia H, Winter L. [The nutritional status change the effectiveness of a dietary supplement of lactic bacteria on the emerging of respiratory tract diseases in children]. Arch Latinoam Nutr. 2002;52:29. PubMed
Vieira AT, Rocha VM, Tavares L, Garcia CC, Teixeira MM, et al. Control of Klebsiella pneumoniae pulmonary infection and immunomodulation by oral treatment with the commensal probiotic Bifidobacterium longum 5(1A). Microbes Infect. 2016;18:180. 10.1016/j.micinf.2015.10.008
Khailova L, Petrie B, Baird CH, Dominguez Rieg JA, Wischmeyer PE. Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis. PLoS One. 2014;9:e97861. 10.1371/journal.pone.0097861
Sazawal S, Dhingra U, Hiremath G, Sarkar A, Dhingra P, et al. Prebiotic and probiotic fortified milk in prevention of morbidities among children: community-based, randomized, double-blind, controlled trial. PLoS One. 2010;5:e12164. 10.1371/journal.pone.0012164