We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.
In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
Read More
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
Read More
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
Read More
Most Useful Reviews
7.5
Reduces blood sugar
5 people found this helpful
Biotin is a vitamin, sometimes referred to as vitamin H or B7, essential for a healthy nervous system, skin, hair, and liver. It plays a crucial role in metabolising carbohydrates, fats, and proteins, converting food into energy. Biotin notably influences glucose production, as its levels inversely affect blood sugar; higher biotin levels lower blood sugar. Thus, biotin supplementation is recommended for those with diabetes. Additionally, adequate levels are vital for maintaining healthy hair and skin, with deficiencies potentially leading to issues such as hair loss and skin irritations.
Read More
7.5
Manages diabetes symptoms
5 people found this helpful
Biotin benefits not only skin and hair but also key bodily functions. It helps utilise enzymes and carry nutrients efficiently. Studies suggest it may assist in regulating blood sugar levels for some individuals with diabetes. Along with enhancing metabolism, biotin could aid in weight loss as well.
Read More
7.5
Controls diabetes effectively
4 people found this helpful
Biotin is an essential vitamin crucial for various metabolic functions and is beneficial for skin, hair, and nail health. It can help control diabetes, alongside promoting stronger hair and nails. Understanding its numerous advantages can make a significant impact on overall health.
We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.
In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
Read More
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
Read More
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
7.5
Reduces blood sugar
5 people found this helpful
Biotin is a vitamin, sometimes referred to as vitamin H or B7, essential for a healthy nervous system, skin, hair, and liver. It plays a crucial role in metabolising carbohydrates, fats, and proteins, converting food into energy. Biotin notably influences glucose production, as its levels inversely affect blood sugar; higher biotin levels lower blood sugar. Thus, biotin supplementation is recommended for those with diabetes. Additionally, adequate levels are vital for maintaining healthy hair and skin, with deficiencies potentially leading to issues such as hair loss and skin irritations.
Read More
7.5
Manages diabetes symptoms
5 people found this helpful
Biotin benefits not only skin and hair but also key bodily functions. It helps utilise enzymes and carry nutrients efficiently. Studies suggest it may assist in regulating blood sugar levels for some individuals with diabetes. Along with enhancing metabolism, biotin could aid in weight loss as well.
Read More
7.5
Controls diabetes effectively
4 people found this helpful
Biotin is an essential vitamin crucial for various metabolic functions and is beneficial for skin, hair, and nail health. It can help control diabetes, alongside promoting stronger hair and nails. Understanding its numerous advantages can make a significant impact on overall health.
Read More
7.5
Supports blood sugar control
Biotin is essential for producing amino acids and fats, and lack of it can lead to several health issues, including dry skin and brittle hair. It's crucial for carbohydrate metabolism, triggering glucose processing, which is vital for people with diabetes. Research indicates that biotin, in conjunction with chromium, can help regulate blood sugar levels, particularly for those with type 2 diabetes. Therefore, I consistently include it in my regimen.
Read More
6
Strengthens hair and nails
4 people found this helpful
Last winter, I noticed increased hair loss and greying, so I decided to take a biotin supplement. After a three-month course, my hair loss reduced, and regrowth appeared healthier. Biotin also strengthened my nails, making them less prone to breaking. Although I combined biotin with other vitamins, I believe it significantly impacted my hair's condition. While biotin may not improve currently grown hair, it aids in addressing underlying issues. Additionally, it may support those with eczema and psoriasis when taken in larger doses under medical supervision.
Diabetes is a chronic medical condition that occurs when the body either does not produce enough insulin or cannot effectively use the insulin it produces. Insulin is a hormone made by the pancreas that helps glucose from food enter the cells, providing them with energy. When diabetes is present, it leads to elevated levels of glucose in the blood, which can cause serious health complications if left unmanaged. There are primarily two types: Type 1 diabetes, which is an autoimmune condition where the body attacks insulin-producing cells, and Type 2 diabetes, which is often associated with lifestyle factors such as obesity and lack of physical activity, leading to insulin resistance.
Managing diabetes typically involves a combination of lifestyle changes, such as a balanced diet and regular exercise, along with monitoring blood sugar levels and, in many cases, medication or insulin therapy. Education is crucial for those with diabetes to understand how their condition works and how to manage it effectively. The goal of diabetes management is to keep blood sugar levels within a target range, helping to prevent complications such as heart disease, nerve damage, and kidney failure. Regular check-ups and consultations with healthcare professionals are essential to ensure optimal care.
Biotin, also known as vitamin B7, is a water-soluble B-vitamin that plays a crucial role in various metabolic processes in the body. It is essential for converting nutrients into energy and is involved in the synthesis of fatty acids, amino acids, and glucose. Biotin is naturally found in a variety of foods, including eggs, nuts, seeds, fish, meat, dairy products, and certain vegetables. While deficiencies are rare due to its abundance in common diets, they can lead to symptoms such as hair loss, skin rashes, and neurological issues.
Many people take biotin supplements believing they can improve hair, skin, and nail health. Although there is some evidence to support the benefits of biotin for hair growth—especially in those with a deficiency—more research is needed to establish its efficacy for those with sufficient levels. The FDA does not regulate dietary supplements as strictly as medications, so it’s crucial to choose high-quality products from reputable manufacturers. Always consult with a healthcare professional before starting any new supplement to ensure it’s appropriate for your specific needs.
Based on user reviews, the time it takes to see results from biotin supplementation for diabetes can vary among individuals. Some users report improvements in symptoms, such as reduced blood sugar levels, within a few months of consistent usage. For instance, one reviewer mentioned that they noticed a significant positive impact on their health after three months, which aligns with other testimonials highlighting gradual improvements in hair and health after a similar duration Read Review.
Moreover, while specific timelines for blood sugar regulation were not consistently mentioned, many users recognize biotin's role in metabolic functions that can assist with diabetes management, suggesting the supplement may gradually contribute to better health outcomes over time Read Review. As results can depend on various factors including individual health, dosage, and other lifestyle variables, it is advisable to maintain consistency and consult a healthcare professional for personalized advice.
When considering the scientific support for diabetes-related supplements, biotin emerges as a noteworthy candidate. Research suggests that biotin supplementation could potentially improve metabolic states in individuals suffering from severe obesity and type 2 diabetes. A study involving over 1,500 subjects found a link between low biotin-producing gut bacteria and inadequate biotin levels in those with severe obesity, indicating that biotin, along with prebiotics, might enhance gut health and help manage blood sugar levels [2]. Furthermore, another investigation into high-dose biotin for type 1 diabetes management hints at potential benefits, especially regarding insulin regulation and blood sugar balance. However, the evidence from early pilot trials remains inconclusive, necessitating further studies to confirm its efficacy [3].
It's important to note that while biotin shows promise, particularly for type 2 diabetes, additional research is required to establish its role more definitively in diabetes care. The advancements in peptide hydrogels present another interesting area, focusing on enhancing islet transplantation outcomes, which indirectly support diabetes management through improved islet function [1]. However, these innovations pertain more to specific therapeutic applications rather than general supplementation. In conclusion, while the research indicates potential pathways for using biotin in diabetes management, particularly for type 2 diabetes, definitive recommendations for its use as a supplement await further validation.
Based on user reviews, users have reported a variety of improvements in symptoms related to biotin supplementation, particularly concerning hair, nails, and blood sugar levels. For example, one user noted a reduction in hair loss and healthier regrowth after three months of taking biotin, highlighting its beneficial impact on hair health Read Review. Others have mentioned that biotin not only strengthened their nails but also contributed to overall metabolic health, with some users specifically noting a decrease in blood glucose levels Read Review, Read Review.
In addition, several individuals cited biotin's role in promoting better metabolic function, which can be particularly beneficial for those managing diabetes. Users indicated that biotin might positively influence glucose processing, making it a recommended supplement for improving overall health and managing diabetes symptoms Read Review. While many reported significant positive changes, individual results can vary, and it is essential to consider personal health factors and consult a healthcare professional for tailored advice.
Users report a positive association between biotin supplementation and its benefits for managing diabetes, particularly when combined with other essential nutrients. Several reviewers highlighted that biotin plays a vital role in carbohydrate metabolism, helping regulate blood sugar levels. One user specifically noted that biotin, when taken alongside chromium, can be particularly effective for glucose processing, especially in individuals with type 2 diabetes Read Review. Another reviewer mentioned that biotin not only aids in metabolic health but also enhances overall bodily functions, including nutrient absorption Read Review.
Moreover, some users shared their experiences of improved health outcomes when combining biotin with other vitamins. One reviewer reported that, after taking biotin along with other supplements, their hair loss decreased and their overall health improved Read Review. The consensus among users seems to support the idea that biotin can effectively support diabetes management while also benefiting hair and skin health, suggesting a multifaceted approach to supplementing for diabetes Read Review.
Users report varying insights regarding the right dose of Biotin for managing diabetes. Generally, it is acknowledged that sufficient biotin levels can play a critical role in glucose metabolism and blood sugar regulation. Some users suggest a combination with chromium may enhance these benefits, particularly for individuals with type 2 diabetes Read Review. Many also share positive experiences regarding biotin's impact not only on metabolic health, but also on hair and skin, indicating that the supplement can provide multiple benefits when included in a daily regimen Read Review.
However, specific dosage recommendations are less frequently mentioned across reviews. While users express satisfaction with the positive effects of biotin on blood sugar levels Read Review, optimal dosing may depend on individual health circumstances and should ideally be discussed with a healthcare provider, especially since higher doses may support conditions like eczema or psoriasis Read Review. Overall, while biotin is lauded for its potential benefits in diabetes management, exact dosage and individual suitability remain topics best addressed in consultation with a healthcare professional.
6
Strengthens hair and nails
4 people found this helpful
Last winter, I noticed increased hair loss and greying, so I decided to take a biotin supplement. After a three-month course, my hair loss reduced, and regrowth appeared healthier. Biotin also strengthened my nails, making them less prone to breaking. Although I combined biotin with other vitamins, I believe it significantly impacted my hair's condition. While biotin may not improve currently grown hair, it aids in addressing underlying issues. Additionally, it may support those with eczema and psoriasis when taken in larger doses under medical supervision.
7.5
Supports blood sugar control
Biotin is essential for producing amino acids and fats, and lack of it can lead to several health issues, including dry skin and brittle hair. It's crucial for carbohydrate metabolism, triggering glucose processing, which is vital for people with diabetes. Research indicates that biotin, in conjunction with chromium, can help regulate blood sugar levels, particularly for those with type 2 diabetes. Therefore, I consistently include it in my regimen.
7.5
Manages diabetes symptoms
5 people found this helpful
Biotin benefits not only skin and hair but also key bodily functions. It helps utilise enzymes and carry nutrients efficiently. Studies suggest it may assist in regulating blood sugar levels for some individuals with diabetes. Along with enhancing metabolism, biotin could aid in weight loss as well.
6
Lowers blood glucose
I took biotin for hair maintenance since it's one of the B vitamins that strengthens nails as well. It also has been shown to reduce blood glucose levels in people with diabetes, making it a good option for metabolic health.
7.5
Controls diabetes effectively
4 people found this helpful
Biotin is an essential vitamin crucial for various metabolic functions and is beneficial for skin, hair, and nail health. It can help control diabetes, alongside promoting stronger hair and nails. Understanding its numerous advantages can make a significant impact on overall health.
7
Biotin supplementation shows potential benefits
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism.
We examined how biotin and prebiotic supplementation may aid metabolism in severe obesity and type 2 diabetes. The study involved metagenomic analyses of 1,545 subjects, showing that severe obesity is linked to low biotin-producing gut bacteria and inadequate biotin levels in the body.
We observed that biotin supplementation, along with prebiotics, could enhance gut health and improve metabolic states, potentially reducing weight gain and blood sugar issues. This suggests promising avenues for preventing metabolic decline in severely obese individuals.
7
Biotin's potential in diabetes management
In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control.
We explored the potential of high-dose biotin to help manage diabetes in individuals with type 1 diabetes. This treatment aims to address the low insulin exposure that affects liver enzyme expression, which is crucial for maintaining balanced blood sugar levels.
Although early pilot trials show some promising outcomes, the results are not definitive enough to confirm significant benefits.
Given its safety, tolerance, and availability, it's clear that further research is needed to fully understand how biotin might be harnessed in diabetes care.
9
Peptide hydrogel boosts islet transplantation
A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1 functionality enhances islet survival to improve islet transplantation outcome in diabetes treatment.
We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.
In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.
References
Cai X, Zhang M, Zou J, Wang L, Zhan Y, et al. A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1 functionality enhances islet survival to improve islet transplantation outcome in diabetes treatment. J Nanobiotechnology. 2024;22:792. doi:10.1186/s12951-024-03072-5
Belda E, Voland L, Tremaroli V, Falony G, Adriouch S, et al. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut. 2022;71:2463. doi:10.1136/gutjnl-2021-325753
McCarty MF. In type 1 diabetics, high-dose biotin may compensate for low hepatic insulin exposure, promoting a more normal expression of glycolytic and gluconeogenic enyzymes and thereby aiding glycemic control. Med Hypotheses. 2016;95:45. doi:10.1016/j.mehy.2016.08.002