Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Excellent
Based on 18 Reviews
9
Supplement Facts
Serving Size:  3 Veg Capsules
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
1.5 g
<1%**
Total Sugars
1.5 g
D-Mannose
1.5 g (1,500 mg)

Top Medical Research Studies

9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.

At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
Read More
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.

Over three months, 100 participants received the supplement, while 50 others served as a control group.

The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Read More
7
Long-term antibiotics reduce UTI recurrence
We examined the effectiveness of long-term antibiotic therapy in preventing recurrent urinary tract infections (UTIs) in postmenopausal women. Our analysis of three small trials indicated that long-term antibiotics could reduce UTI recurrence by about 24%.

However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
Read More

Most Useful Reviews

9.5
Pain relief achieved
Perfectly! D-Mannose was my solution during this challenging menopause phase. At 49, I struggled with debilitating cystitis. After six months of antibiotics, I sought alternatives and tried D-Mannose, taking 4 capsules five times a day. Improvement was immediate! Now, a life free from pain and antibiotics feels possible! For anyone suffering similarly, D-Mannose and cranberries are miraculous.
Read More
9.5
No more UTIs
I adore D-Mannose and wish I had discovered it sooner! During menopause, I faced recurrent UTIs, but since taking Mannose, I haven’t had any problems. I’m also a caretaker, which often complicates things. I’m thankful for this solution, and my son, who has urinary issues, benefits from it as well.
Read More
9.5
Long-lasting relief
D-Mannose truly changed my life after years of bladder discomfort, particularly post-menopause. Initially sceptical, I tried D-Mannose based on a recommendation. I felt better within two days, now taking 2 capsules nightly for prevention. Remarkably, I haven’t had a UTI in over a year!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
  • All Researches
9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.

At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
Read More
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.

Over three months, 100 participants received the supplement, while 50 others served as a control group.

The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Read More
7
Long-term antibiotics reduce UTI recurrence
We examined the effectiveness of long-term antibiotic therapy in preventing recurrent urinary tract infections (UTIs) in postmenopausal women. Our analysis of three small trials indicated that long-term antibiotics could reduce UTI recurrence by about 24%.

However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 18 Reviews
9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Pain relief achieved
Perfectly! D-Mannose was my solution during this challenging menopause phase. At 49, I struggled with debilitating cystitis. After six months of antibiotics, I sought alternatives and tried D-Mannose, taking 4 capsules five times a day. Improvement was immediate! Now, a life free from pain and antibiotics feels possible! For anyone suffering similarly, D-Mannose and cranberries are miraculous.
Read More
9.5
No more UTIs
I adore D-Mannose and wish I had discovered it sooner! During menopause, I faced recurrent UTIs, but since taking Mannose, I haven’t had any problems. I’m also a caretaker, which often complicates things. I’m thankful for this solution, and my son, who has urinary issues, benefits from it as well.
Read More
9.5
Long-lasting relief
D-Mannose truly changed my life after years of bladder discomfort, particularly post-menopause. Initially sceptical, I tried D-Mannose based on a recommendation. I felt better within two days, now taking 2 capsules nightly for prevention. Remarkably, I haven’t had a UTI in over a year!
Read More
9.5
Effective solution
At 50, menopause brought painful cystitis symptoms. After antibiotics proved ineffective, I searched for alternatives. I discovered D-Mannose and saw results quickly, taking 3 capsules three times daily to quell symptoms. Remarkably, the discomfort vanished within three days. Highly recommended for E. coli related issues!
Read More
9.5
Maintained health
Menopause is challenging with numerous physical changes. D-Mannose helped me with urinary tract health. I began with three capsules daily during infections but now take just one for maintenance, remaining irritation-free for nearly two years!
Read More

Frequently Asked Questions

Menopause is a natural biological process that marks the end of a woman's reproductive years, characterized by the cessation of menstruation and a decline in hormonal levels, particularly estrogen and progesterone. Typically occurring between the ages of 45 and 55, menopause can bring a variety of physical and emotional changes. Common symptoms may include hot flashes, night sweats, mood swings, and changes in sleep patterns. It is important to note that menopause is a gradual process and often begins with perimenopause, where women may experience irregular periods and increased symptoms for several years before periods stop completely.

While menopause is a natural phase of life, it can have significant impacts on a woman's health and well-being. This transition can increase the risk of certain health issues, such as osteoporosis and cardiovascular disease, due in part to lowered hormone levels. Therefore, it is advisable for women to consult with healthcare providers to discuss potential management strategies and lifestyle adjustments during this time. These may include hormone replacement therapy, dietary changes, regular physical activity, and alternative therapies, all aimed at alleviating symptoms and promoting overall health during and after menopause.

D-mannose is a type of simple sugar that is closely related to glucose. It is naturally found in various fruits and plants, including cranberries, apples, and peaches. D-mannose has garnered attention primarily for its potential benefits in supporting urinary tract health. Research suggests that it may help prevent urinary tract infections (UTIs) by inhibiting the adhesion of bacteria, such as E. coli, to the walls of the urinary tract.

Many people consider D-mannose as a natural supplement to support urinary tract function, particularly for those who experience recurrent UTIs. Available in powder or capsule form, it is often taken for preventative purposes or during an active infection, thanks to its ability to promote urinary health. While more research is needed to fully establish its efficacy, D-mannose is generally regarded as safe for most individuals, albeit it’s always a good practice to consult with a healthcare professional before beginning any new supplement regimen.

Based on user reviews, the time frame for seeing results from D-Mannose during menopause can vary, but many users report prompt improvements. For instance, one user shared that they felt better within just two days of starting the supplement, while another noted a significant reduction in discomfort after only three days of use (Read Review) (Read Review). Some users have had success in managing their conditions with consistent usage over longer periods, with dramatic relief from symptoms after several weeks or even months of regular intake (Read Review) (Read Review).

Overall, while many users suggest that noticeable benefits can begin to appear within days, those seeking long-term solutions often mention that ongoing use is necessary to maintain effectiveness. It's worth noting that individual responses can differ, so it's advisable to monitor one’s own body's reaction and consult with a healthcare provider for personalized guidance (Read Review).

Recent research suggests that certain supplements can offer effective relief for urinary issues often experienced during menopause. A study examining a nutraceutical compound featuring D-mannose, in combination with cranberry and other ingredients, demonstrated a significant decrease in recurrent urinary tract infections (UTIs) among menopausal women over a twelve-month period, indicating its potential as a natural remedy for those affected by frequent infections [1]. In another study, a supplement containing D-mannose and cranberry showed promising results for managing urinary disorders in women aged 40 to 50, which aligns with the common concerns of those approaching menopause [2].

While these findings are promising, they specifically highlight urinary health rather than an overall approach to menopause symptoms, which can be diverse and complex. Thus, while supplements like D-mannose may support urinary health for menopausal women, it's essential to consider other aspects of menopause that might require different interventions. More comprehensive research could further clarify the full scope of benefits these or other supplements might provide during menopause.

Based on user reviews, many individuals experiencing menopause have reported significant improvements in urinary symptoms after using D-Mannose. For example, one user noted an immediate enhancement in their condition, highlighting a life free from pain and the need for antibiotics within just six months of starting the supplement (Read Review). Another user experienced noticeable relief after a mere three days, while some have celebrated years without urinary tract infections (UTIs) following consistent use, emphasizing the product's long-term effectiveness for maintenance (Read Review).

Users have also indicated that D-Mannose not only alleviates discomfort related to recurrent UTIs but also aids in overall bladder health. Several respondents have shared that using D-Mannose has reduced the frequency of infections and improved their ability to manage symptoms during menopause (Read Review). However, it's essential to note that individual results can vary, and what works for one person may not be suitable for another. As always, consulting with a healthcare provider is recommended to tailor the approach to one's specific needs (Read Review).

Based on user reviews, many individuals reported positive experiences when combining D-Mannose with other supplements to manage menopause-related urinary symptoms. For example, one user shared that they take D-Mannose alongside Go-Less, which contains phytoestrogens for enhanced bladder health, emphasizing the benefits of combining the two (Read Review). Additionally, another user mentioned using D-Mannose in conjunction with cranberry extract, which they found helpful for addressing urogenital disorders linked to decreased estrogen during menopause (Read Review).

Users have expressed that these combinations may provide a more comprehensive approach to alleviating symptoms. For instance, one review pointed out that combining D-Mannose with inulin aids in treating cystitis while supporting intestinal microbiota, which is vital for displacing harmful bacteria (Read Review). Overall, while individual results vary, many women recommend exploring the synergy of D-Mannose with other supplements as an effective strategy for managing menopause-related urinary health challenges.

Based on user reviews, there is a variety of doses reported for D-Mannose among women experiencing symptoms related to menopause. Many users found success with doses ranging from 2 to 5 grams per day. For example, one user mentioned taking 2 grams daily, increasing to 5 grams at the onset of symptoms, which significantly reduced her urinary tract infections (UTIs) (Read Review). Another user shared that taking 3 capsules three times a day relieved her symptoms within just three days (Read Review). Others reported success with lower doses, such as 2 capsules nightly for long-term prevention (Read Review) or splitting doses into smaller amounts for maintenance (Read Review).

9.5
Long-lasting relief
D-Mannose truly changed my life after years of bladder discomfort, particularly post-menopause. Initially sceptical, I tried D-Mannose based on a recommendation. I felt better within two days, now taking 2 capsules nightly for prevention. Remarkably, I haven’t had a UTI in over a year!
9.5
Effective solution
At 50, menopause brought painful cystitis symptoms. After antibiotics proved ineffective, I searched for alternatives. I discovered D-Mannose and saw results quickly, taking 3 capsules three times daily to quell symptoms. Remarkably, the discomfort vanished within three days. Highly recommended for E. coli related issues!
9.5
Maintained health
Menopause is challenging with numerous physical changes. D-Mannose helped me with urinary tract health. I began with three capsules daily during infections but now take just one for maintenance, remaining irritation-free for nearly two years!
7.5
Discomfort relief
Due to menopause, urination became inconvenient, but after two months of taking this along with Clean Barry, the discomfort has disappeared.
9.5
Reduced infections
My urologist recommended D-Mannose to minimise urinary tract infections. I take 2g daily, increasing to 5g if I sense an infection beginning. Since starting, infections have significantly decreased.
9.5
Pain relief achieved
Perfectly! D-Mannose was my solution during this challenging menopause phase. At 49, I struggled with debilitating cystitis. After six months of antibiotics, I sought alternatives and tried D-Mannose, taking 4 capsules five times a day. Improvement was immediate! Now, a life free from pain and antibiotics feels possible! For anyone suffering similarly, D-Mannose and cranberries are miraculous.
9.5
Bladder improvement
Menopause turned my life into a nightmare with severe overactive bladder symptoms. After trying many antibiotics, I decided to try mannose and cranberries at my daughter's suggestion. Remarkably, I now have a calm interval of 2.5 hours between toilet visits.
8.8
Long-term benefits
I'm 56, experiencing urinary symptoms tied to menopause. D-Mannose has been beneficial, and I now take it long-term, alongside Go-Less, which contains phytoestrogens for bladder health.
8.8
Preventive measure
During menopause, I noticed urogenital disorders due to reduced oestrogen. I take this supplement for prevention, especially given my age. I also include cranberry extract in my routine.
8.8
Urogenital support
D-mannose has anti-inflammatory and antitumour properties. During menopause, decreased oestrogen can lead to urogenital issues. Using D-mannose with inulin helps treat cystitis while normalising intestinal microbiota, which is crucial for displacing harmful bacteria.
8.8
Urinary relief
Menopausal women experience weak resistance and are prone to urinary tract infections. Taking three capsules when I feel a tingling sensation while urinating effectively relieves the discomfort and normalises my urine test results. For daily maintenance, I take two capsules each morning and evening.
9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.

At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.

Over three months, 100 participants received the supplement, while 50 others served as a control group.

The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.

References

  1. Mainini G, Passaro M, Schiattarella A, Franciscis P, Donna MCD, et al. Prevention and treatment of cystitis during menopause: efficacy of a nutraceutical containing D-mannose, inulin, cranberry, bearberry, and . Prz Menopauzalny. 2020;19:130. doi:10.5114/pm.2020.99567
  2. DE Leo V, Cappelli V, Massaro MG, Tosti C, Morgante G. [Evaluation of the effects of a natural dietary supplement with cranberry, Noxamicina® and D-mannose in recurrent urinary infections in perimenopausal women]. Minerva Ginecol. 2017;69:336. doi:10.23736/S0026-4784.17.04074-6
  3. Ahmed H, Davies F, Francis N, Farewell D, Butler C, et al. Long-term antibiotics for prevention of recurrent urinary tract infection in older adults: systematic review and meta-analysis of randomised trials. BMJ Open. 2017;7:e015233. doi:10.1136/bmjopen-2016-015233
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