Last update
4/4/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1.5 g
<1%**
Total Sugars
1.5 g
†
D-Mannose
1.5 g (1,500 mg)
†
Top Medical Research Studies
9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
Read More
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Read More
7
Long-term antibiotics reduce UTI recurrence
We examined the effectiveness of long-term antibiotic therapy in preventing recurrent urinary tract infections (UTIs) in postmenopausal women. Our analysis of three small trials indicated that long-term antibiotics could reduce UTI recurrence by about 24%.
However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
Read More
Most Useful Reviews
9
Infection deterrent
This product is essential for middle-aged women. Urinary infections during early menopause can be persistent. I rely on this remedy to manage my condition instead of frequent doctor visits.
Read More
7.5
Improved comfort
1 people found this helpful
I entered menopause early and faced frequent urination issues. After using D-Mannose for over a week, I find it effective for alleviating discomfort and will definitely repurchase.
Read More
7.5
Urinary relief
1 people found this helpful
Menopausal women experience weak resistance and are prone to urinary tract infections. Taking three capsules when I feel a tingling sensation while urinating effectively relieves the discomfort and normalises my urine test results. For daily maintenance, I take two capsules each morning and evening.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
Read More
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Read More
7
Long-term antibiotics reduce UTI recurrence
We examined the effectiveness of long-term antibiotic therapy in preventing recurrent urinary tract infections (UTIs) in postmenopausal women. Our analysis of three small trials indicated that long-term antibiotics could reduce UTI recurrence by about 24%.
However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
However, we found no significant evidence on the therapy's benefits or risks for older men or frail care home residents. Importantly, concerns arose regarding antibiotic resistance linked to such treatments, highlighting the need for caution and further research.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Infection deterrent
This product is essential for middle-aged women. Urinary infections during early menopause can be persistent. I rely on this remedy to manage my condition instead of frequent doctor visits.
Read More
7.5
Improved comfort
1 people found this helpful
I entered menopause early and faced frequent urination issues. After using D-Mannose for over a week, I find it effective for alleviating discomfort and will definitely repurchase.
Read More
7.5
Urinary relief
1 people found this helpful
Menopausal women experience weak resistance and are prone to urinary tract infections. Taking three capsules when I feel a tingling sensation while urinating effectively relieves the discomfort and normalises my urine test results. For daily maintenance, I take two capsules each morning and evening.
Read More
7.5
Effective remedy
My gynaecologist recommended this remedy for cystitis, especially during menopause. These capsules work well to alleviate the discomfort I experienced.
Read More
7.5
Discomfort relief
Due to menopause, urination became inconvenient, but after two months of taking this along with Clean Barry, the discomfort has disappeared.
Read More
Frequently Asked Questions
7.5
Discomfort relief
Due to menopause, urination became inconvenient, but after two months of taking this along with Clean Barry, the discomfort has disappeared.
7.5
Urinary relief
1 people found this helpful
Menopausal women experience weak resistance and are prone to urinary tract infections. Taking three capsules when I feel a tingling sensation while urinating effectively relieves the discomfort and normalises my urine test results. For daily maintenance, I take two capsules each morning and evening.
9
D-mannose aids menopausal UTI management
We evaluated the effectiveness of a nutraceutical compound featuring D-mannose, along with cranberry, bearberry, and inulin, in treating recurrent urinary tract infections (UTIs) among menopausal women. In our cohort study, women took this treatment for ten days each month.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
At six months, there was a notable decrease in women experiencing recurrent UTIs compared to their baseline. Additionally, at the twelve-month mark, more participants in the treatment group reported being infection-free and showed significant improvement in UTI-related symptoms.
9
D-mannose shows potential benefits
We conducted a study on the effectiveness of Kistinox® Forte, a dietary supplement containing cranberry, Noxamicina®, and D-mannose, for treating urinary disorders in women aged 40 to 50.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
Over three months, 100 participants received the supplement, while 50 others served as a control group.
The results highlighted the supplement's excellent efficacy and tolerability, showing promise in managing recurrent cystitis, which is a common concern for women in this age group.
References
- Mainini G, Passaro M, Schiattarella A, Franciscis P, Donna MCD, et al. Prevention and treatment of cystitis during menopause: efficacy of a nutraceutical containing D-mannose, inulin, cranberry, bearberry, and . Prz Menopauzalny. 2020;19:130. 10.5114/pm.2020.99567
- DE Leo V, Cappelli V, Massaro MG, Tosti C, Morgante G. [Evaluation of the effects of a natural dietary supplement with cranberry, Noxamicina® and D-mannose in recurrent urinary infections in perimenopausal women]. Minerva Ginecol. 2017;69:336. 10.23736/S0026-4784.17.04074-6
- Ahmed H, Davies F, Francis N, Farewell D, Butler C, et al. Long-term antibiotics for prevention of recurrent urinary tract infection in older adults: systematic review and meta-analysis of randomised trials. BMJ Open. 2017;7:e015233. 10.1136/bmjopen-2016-015233
Data last updated:
