Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
USERS' SCORE
Good
Based on 8 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**

Top Medical Research Studies

9
Myo-inositol reduces thyroid nodule size
We conducted an observational study to explore how myo-inositol (MI) combined with selenium (Se) impacts patients with subclinical hypothyroidism (SCH) and associated thyroid nodules (TNs).

Our research involved 642 patients suspected of having hypothyroidism, focusing on a subset with SCH. We divided them into two groups: one that received the MI plus Se treatment for six months and a control group that did not receive any treatment.

Among the received results, we found that the treatment group showed a significant reduction in the size and number of mixed TNs, alongside an improved elasticity score. Remarkably, TSH levels also dropped significantly after treatment, indicating a positive response. In contrast, the control group experienced an increase in TSH levels, highlighting the potential benefits of MI plus Se for managing symptoms of hypothyroidism.

These findings suggest promising avenues for further research, particularly regarding the role of inositol in thyroid health. While we observed substantial benefits in the treated group, we also emphasize the need for more extensive studies to confirm these effects and their mechanisms.
We explored the effective role of Myo-Inositol (MYO) in thyroid health, particularly its impact on subclinical hypothyroidism. This study looked into how MYO serves as a precursor in the thyroid hormone signaling process and the associated phosphoinositide pathways.

By analyzing treatment outcomes, we observed that when patients with subclinical hypothyroidism received Myo-Inositol along with Selenium, their thyroid-stimulating hormone (TSH) levels significantly decreased. This reduction in TSH was paired with a decline in thyroid autoantibodies, suggesting that MYO might effectively enhance thyroid function and immune response.

Additionally, there's emerging evidence supporting the use of Myo-Inositol in managing benign thyroid nodules, hinting at a potential for size reduction. Overall, our findings indicate that Myo-Inositol could be a valuable component in thyroid disease treatment, particularly for subclinical hypothyroidism.
9.5
Myo-Inositol and Selenium Effective
We explored the potential benefits of combining myo-inositol and selenium in patients with autoimmune thyroiditis, particularly those dealing with subclinical hypothyroidism. Our study included 86 patients who had elevated thyroid-stimulating hormone (TSH) levels but normal thyroid hormone levels, indicating early signs of thyroid dysfunction.

After six months of treatment with myo-inositol and selenium, we observed significant changes: TSH levels decreased, while important thyroid hormone markers, TPOAb and TgAb, also showed reduction. Interestingly, we noted an improvement in the overall quality of life for the patients involved in the study.

A special case of one hyperthyroid patient stood out; their TSH levels showed a positive shift from 0.14 U/ml to 1.02 U/ml, bringing them back into a normal range. This suggests that combined treatment with myo-inositol and selenium not only aids in reducing thyroid-related antibodies but also promotes a healthier thyroid overall.

In summary, our findings indicate that integrating myo-inositol with selenium can effectively support thyroid health for those affected by autoimmune thyroiditis.

Most Useful Reviews

9
Effective treatment
1 people found this helpful
Inositol is a vital precursor to phospholipids, essential components of cell membranes. It aids in nutrient transfer and fat conversion. This specific product contains crystalline inositol and has been effectively used in treating hypothyroidism. I found it to be one of the best options available after testing many samples, and I wholeheartedly recommend it!
9
Anxiety relief
Fast delivery! Inositol has significantly helped my hypothyroidism and anxiety. Many thanks to iHerb!
7.5
Increased energy
18 people found this helpful
I experienced an immediate surge of strength when taking Inositol in combination with selenium and taurine to reduce TSH and thyroxine dosage. As someone with hypothyroidism, this has been beneficial. It's essentially vitamin B8 and is particularly useful for women facing challenges in planning a pregnancy.

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
  • All Researches
9.5
Myo-Inositol and Selenium Effective
We explored the potential benefits of combining myo-inositol and selenium in patients with autoimmune thyroiditis, particularly those dealing with subclinical hypothyroidism. Our study included 86 patients who had elevated thyroid-stimulating hormone (TSH) levels but normal thyroid hormone levels, indicating early signs of thyroid dysfunction.

After six months of treatment with myo-inositol and selenium, we observed significant changes: TSH levels decreased, while important thyroid hormone markers, TPOAb and TgAb, also showed reduction. Interestingly, we noted an improvement in the overall quality of life for the patients involved in the study.

A special case of one hyperthyroid patient stood out; their TSH levels showed a positive shift from 0.14 U/ml to 1.02 U/ml, bringing them back into a normal range. This suggests that combined treatment with myo-inositol and selenium not only aids in reducing thyroid-related antibodies but also promotes a healthier thyroid overall.

In summary, our findings indicate that integrating myo-inositol with selenium can effectively support thyroid health for those affected by autoimmune thyroiditis.
9
Myo-inositol and selenium aid hypothyroidism
In our recent study, we explored the effects of myo-inositol combined with selenium on women diagnosed with subclinical hypothyroidism. We included 148 participants from eight centers across Slovakia, all women of reproductive age. These women displayed thyroid-stimulating hormone (TSH) levels indicating subclinical hypothyroidism and some exhibited autoimmune markers.

The treatment involved a daily supplementation of 600 mg of myo-inositol and 83 mcg of selenium over a period of six months. We carefully monitored changes in TSH levels, symptoms associated with hypothyroidism, and overall thyroid function throughout this time.

Our findings revealed a significant improvement in TSH levels among the participants after the supplement regimen. Additionally, there was a notable reduction in autoimmune antibody levels for a subset of patients. Many women reported improvements in their menstrual cycles and a decrease in cholesterol levels, which often aligns with thyroid health.

This combination of myo-inositol and selenium not only appeared to stabilize thyroid function but also alleviated the symptoms linked to subclinical hypothyroidism. Overall, our research indicates the potential benefits of these supplements in managing this condition.
We explored the effects of myo-inositol (Myo-Ins) on individuals with hypothyroidism, particularly those diagnosed with autoimmune thyroiditis. In recent studies, patients were treated with a combination of Myo-Ins and seleniomethionine, which led to significant declines in thyroid-stimulating hormone (TSH) levels. This suggests that Myo-Ins may play a role in managing subclinical hypothyroidism.

Importantly, the treatment also resulted in a decrease in antithyroid autoantibodies and serum CXCL10 levels, indicating an immune-modulatory effect of Myo-Ins. However, it’s crucial to note that because Myo-Ins was evaluated alongside seleniomethionine, it's difficult to determine the specific benefits attributed solely to inositol.

Overall, while the combined treatment shows promise, further research with larger populations is necessary to fully understand Myo-Ins’ impact on quality of life and its mechanisms, especially regarding chemokines.
9
Myo-inositol reduces thyroid nodule size
We conducted an observational study to explore how myo-inositol (MI) combined with selenium (Se) impacts patients with subclinical hypothyroidism (SCH) and associated thyroid nodules (TNs).

Our research involved 642 patients suspected of having hypothyroidism, focusing on a subset with SCH. We divided them into two groups: one that received the MI plus Se treatment for six months and a control group that did not receive any treatment.

Among the received results, we found that the treatment group showed a significant reduction in the size and number of mixed TNs, alongside an improved elasticity score. Remarkably, TSH levels also dropped significantly after treatment, indicating a positive response. In contrast, the control group experienced an increase in TSH levels, highlighting the potential benefits of MI plus Se for managing symptoms of hypothyroidism.

These findings suggest promising avenues for further research, particularly regarding the role of inositol in thyroid health. While we observed substantial benefits in the treated group, we also emphasize the need for more extensive studies to confirm these effects and their mechanisms.
9
Supplementation improves thyroid function
We explored the effectiveness of myo-inositol (MI) and selenium (Se) supplements in treating Hashimoto's thyroiditis, specifically for patients dealing with subclinical hypothyroidism (SH). In this study, 168 participants with elevated Thyroid Stimulating Hormone (TSH) levels were split into two groups: one received both MI and Se, while the other group was given Se alone.

After six months of treatment, we observed significant improvements in the group taking MI-Se. Notably, TSH levels, along with anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) antibodies, saw a marked decrease. Moreover, there was a notable rise in free serum T4 levels for those on the combined treatment, which also contributed positively to their overall quality of life.

In conclusion, our findings suggest that the combination of MI and Se is an effective strategy for reinstating normal thyroid function in patients with autoimmune thyroiditis, thus restoring their wellbeing.

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective treatment
1 people found this helpful
Inositol is a vital precursor to phospholipids, essential components of cell membranes. It aids in nutrient transfer and fat conversion. This specific product contains crystalline inositol and has been effectively used in treating hypothyroidism. I found it to be one of the best options available after testing many samples, and I wholeheartedly recommend it!
9
Anxiety relief
Fast delivery! Inositol has significantly helped my hypothyroidism and anxiety. Many thanks to iHerb!
7.5
Increased energy
18 people found this helpful
I experienced an immediate surge of strength when taking Inositol in combination with selenium and taurine to reduce TSH and thyroxine dosage. As someone with hypothyroidism, this has been beneficial. It's essentially vitamin B8 and is particularly useful for women facing challenges in planning a pregnancy.
7.5
Reduces cravings
11 people found this helpful
My Masthev ... and it works! I have hypothyroidism and asthma, which means I’m also overweight. In the first month, I took 4000 mg of Inositol per day, divided into two doses with meals. In the first week, my cravings for sweets vanished completely. I’ve since reduced my dosage to 2000 mg daily. I switched to powder, which I find more convenient. Before starting any new supplement, it's important to consult your doctor. Wishing everyone success! ❤️
7.5
Effective support
This supplement provides excellent assistance with both AIT and hypothyroidism.

Frequently Asked Questions

7.5
Increased energy
18 people found this helpful
I experienced an immediate surge of strength when taking Inositol in combination with selenium and taurine to reduce TSH and thyroxine dosage. As someone with hypothyroidism, this has been beneficial. It's essentially vitamin B8 and is particularly useful for women facing challenges in planning a pregnancy.
7.5
Reduces cravings
11 people found this helpful
My Masthev ... and it works! I have hypothyroidism and asthma, which means I’m also overweight. In the first month, I took 4000 mg of Inositol per day, divided into two doses with meals. In the first week, my cravings for sweets vanished completely. I’ve since reduced my dosage to 2000 mg daily. I switched to powder, which I find more convenient. Before starting any new supplement, it's important to consult your doctor. Wishing everyone success! ❤️
7.5
Health improvement
I've heard many positive reviews about inositol. With my hypothyroidism, these capsules were recommended to me, and I’ve noticed an improvement in both my health and thyroid function. However, I also take selenium and magnesium, so I can't be certain that this supplement alone is the reason for my improvement.
6
Supports fertility
17 people found this helpful
Inositol is a highly versatile vitamin-like substance that affects the entire body. It enhances communication between the pituitary gland, hypothalamus, and peripheral endocrine glands, being particularly useful for hypothyroidism, AIT, and PCOS. I took 750 mg daily for six months to support my fertility. Remarkably, my menstrual cycle stabilised to a regular 28 days instead of the previous 23-25 days. I've ordered more now.
9
Anxiety relief
Fast delivery! Inositol has significantly helped my hypothyroidism and anxiety. Many thanks to iHerb!
9
Myo-inositol and selenium aid hypothyroidism
In our recent study, we explored the effects of myo-inositol combined with selenium on women diagnosed with subclinical hypothyroidism. We included 148 participants from eight centers across Slovakia, all women of reproductive age. These women displayed thyroid-stimulating hormone (TSH) levels indicating subclinical hypothyroidism and some exhibited autoimmune markers.

The treatment involved a daily supplementation of 600 mg of myo-inositol and 83 mcg of selenium over a period of six months. We carefully monitored changes in TSH levels, symptoms associated with hypothyroidism, and overall thyroid function throughout this time.

Our findings revealed a significant improvement in TSH levels among the participants after the supplement regimen. Additionally, there was a notable reduction in autoimmune antibody levels for a subset of patients. Many women reported improvements in their menstrual cycles and a decrease in cholesterol levels, which often aligns with thyroid health.

This combination of myo-inositol and selenium not only appeared to stabilize thyroid function but also alleviated the symptoms linked to subclinical hypothyroidism. Overall, our research indicates the potential benefits of these supplements in managing this condition.
We examined how myoinositol, a form of inositol, impacts hypothyroidism, especially in relation to autoimmune thyroiditis. Our focus was on its potential to improve thyroid function by affecting important processes like iodine organification and the production of thyroid hormones.

In this context, we found that participants with subclinical hypothyroidism saw significant reductions in thyroid-stimulating hormone (TSH) levels after treatment with a combination of myoinositol and selenium. This suggests that myoinositol could play an important role in managing thyroid issues. Additionally, we noticed a decrease in antithyroid autoantibodies, which further indicates that myoinositol may help those dealing with autoimmune thyroid conditions.

Overall, our findings suggest that myoinositol has a beneficial effect on thyroid health, particularly in supporting those with hypothyroidism and autoimmune thyroiditis. The combination of myoinositol and selenium could be a promising approach for better thyroid management.
We explored the effectiveness of myo-inositol in combination with selenium for treating autoimmune thyroiditis (AIT) and how this combination impacts thyroid hormone levels. Through a systematic review and meta-analysis of various studies, we found that supplementing selenium with myo-inositol led to a significant reduction in thyroid-stimulating hormone (TSH) levels compared to taking selenium alone. Additionally, we observed a notable decline in thyroglobulin antibodies (TgAb) in the combined treatment group.

However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
9
Supplementation improves thyroid function
We explored the effectiveness of myo-inositol (MI) and selenium (Se) supplements in treating Hashimoto's thyroiditis, specifically for patients dealing with subclinical hypothyroidism (SH). In this study, 168 participants with elevated Thyroid Stimulating Hormone (TSH) levels were split into two groups: one received both MI and Se, while the other group was given Se alone.

After six months of treatment, we observed significant improvements in the group taking MI-Se. Notably, TSH levels, along with anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) antibodies, saw a marked decrease. Moreover, there was a notable rise in free serum T4 levels for those on the combined treatment, which also contributed positively to their overall quality of life.

In conclusion, our findings suggest that the combination of MI and Se is an effective strategy for reinstating normal thyroid function in patients with autoimmune thyroiditis, thus restoring their wellbeing.

References

  1. Zuhair V, Sheikh AT, Shafi N, Babar A, Khan A, et al. Role of Supplementation with Selenium and Myo-Inositol Versus Selenium Alone in Patients of Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. Clin Med Insights Endocrinol Diabetes. 2024;17:11795514241300998. doi:10.1177/11795514241300998
  2. Payer J, Jackuliak P, Kužma M, Džupon M, Vaňuga P. Supplementation with myo-inositol and Selenium improves the clinical conditions and biochemical features of women with or at risk for subclinical hypothyroidism. Front Endocrinol (Lausanne). 2022;13:1067029. doi:10.3389/fendo.2022.1067029
  3. Paparo SR, Ferrari SM, Patrizio A, Elia G, Ragusa F, et al. Myoinositol in Autoimmune Thyroiditis. Front Endocrinol (Lausanne). 2022;13:930756. doi:10.3389/fendo.2022.930756
  4. Benvenga S, Nordio M, Laganà AS, Unfer V. The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management. Front Endocrinol (Lausanne). 2021;12:662582. doi:10.3389/fendo.2021.662582
  5. Pace C, Tumino D, Russo M, Le Moli R, Naselli A, et al. Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression. Endocr J. 2020;67:1093. doi:10.1507/endocrj.EJ20-0062
  6. Fallahi P, Ferrari SM, Elia G, Ragusa F, Paparo SR, et al. Myo-inositol in autoimmune thyroiditis, and hypothyroidism. Rev Endocr Metab Disord. 2018;19:349. doi:10.1007/s11154-018-9477-9
  7. Nordio M, Basciani S. Evaluation of thyroid nodule characteristics in subclinical hypothyroid patients under a myo-inositol plus selenium treatment. Eur Rev Med Pharmacol Sci. 2018;22:2153. doi:10.26355/eurrev_201804_14749
  8. Nordio M, Basciani S. Myo-inositol plus selenium supplementation restores euthyroid state in Hashimoto's patients with subclinical hypothyroidism. Eur Rev Med Pharmacol Sci. 2017;21:51.
  9. Ferrari SM, Fallahi P, Di Bari F, Vita R, Benvenga S, et al. Myo-inositol and selenium reduce the risk of developing overt hypothyroidism in patients with autoimmune thyroiditis. Eur Rev Med Pharmacol Sci. 2017;21:36.
  10. Nordio M, Basciani S. Treatment with Myo-Inositol and Selenium Ensures Euthyroidism in Patients with Autoimmune Thyroiditis. Int J Endocrinol. 2017;2017:2549491. doi:10.1155/2017/2549491
  11. Nordio M, Pajalich R. Combined treatment with Myo-inositol and selenium ensures euthyroidism in subclinical hypothyroidism patients with autoimmune thyroiditis. J Thyroid Res. 2013;2013:424163. doi:10.1155/2013/424163
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