We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
N-acetyltaurine impacts obesity control
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids spinal cord recovery
Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway.
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.
Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.
We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.
Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
Read More
Most Useful Reviews
9
Stabilises blood sugar
52 people found this helpful
I appreciate taurine for stabilising sugars in diabetes. It prevents surges and has improved my health for six months. It does not raise blood pressure, so I take it without worry.
Read More
7.5
Eyesight improvement
5 people found this helpful
Taurine is crucial for heart health and diabetes management. It enhances glucose metabolism, supports eye health, and has improved my energy and mood significantly.
Read More
7.5
Insulin resistance remedy
91 people found this helpful
A good remedy for insulin resistance and diabetes. It offers excellent value for money, just like other products from NOW.
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
Taurine's role in diabetic wound healing
Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing.
We explored the role of taurine, a naturally occurring amino acid, in healing diabetic wounds. The study developed innovative patches that combine taurine with cerium dioxide, creating a unique treatment tool designed to tackle the challenges of wound healing in diabetes.
By using microneedle technology, these patches ensure that the beneficial components penetrate deep into the wound tissue. This method enhances the effectiveness of taurine, allowing it to help reduce oxidative stress and low-level inflammation commonly associated with non-healing diabetic wounds.
Our findings revealed that these specially designed patches not only stimulate healing but also improve the overall immune environment, making it easier for the body to repair damaged tissue. Ultimately, the approach harnesses taurine's antioxidant and anti-inflammatory properties, showing promising results in facilitating wound closure in diabetic patients.
Overall, the study highlights the potential of combining taurine with advanced delivery methods in overcoming obstacles to effective diabetic wound healing.
Read More
9
N-acetyltaurine impacts obesity control
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids diabetic wound healing
Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing.
We delved into how taurine, paired with chitosan, can assist in healing wounds, especially in the context of diabetes. The study involved creating chitosan-taurine nanoparticles, which were then mixed into carboxymethyl chitosan hydrogels. This innovative combination aimed to enhance how well and how quickly wounds heal.
Our findings showed that these special hydrogel dressings not only supported better biodegradation and biocompatibility, but they also encouraged healing processes like angiogenesis—the formation of new blood vessels. The inclusion of taurine appears to have anti-inflammatory properties and promotes the movement and growth of cells essential for healing.
Importantly, tests on mice demonstrated that these dressings significantly improved wound healing in both acute and chronic diabetic conditions. We observed that the sustained release of taurine from the hydrogels has great potential for clinical applications in treating various types of wounds, making our study an exciting step forward in wound care.
I appreciate taurine for stabilising sugars in diabetes. It prevents surges and has improved my health for six months. It does not raise blood pressure, so I take it without worry.
Read More
7.5
Eyesight improvement
5 people found this helpful
Taurine is crucial for heart health and diabetes management. It enhances glucose metabolism, supports eye health, and has improved my energy and mood significantly.
Read More
7.5
Insulin resistance remedy
91 people found this helpful
A good remedy for insulin resistance and diabetes. It offers excellent value for money, just like other products from NOW.
Read More
7.5
Metabolic enhancement
38 people found this helpful
Taurine prevents lipid oxidation, improves metabolic processes and lowers glucose levels in diabetics. I was advised to take it before meals, and I found it effective for weight loss and concentration.
Read More
7.5
Enhanced energy levels
31 people found this helpful
Literally saved my life. This product turned my life around. Since adding it to my tea, I feel energised for the first time in years. I have chronic depression, diabetes, and arthritis, but now I can move more easily, which helps immensely with both conditions. I'm uncertain if it's just a cycle, but I finally have energy again.
Diabetes is a chronic medical condition that occurs when the body either does not produce enough insulin or cannot effectively use the insulin it produces. Insulin is a hormone made by the pancreas that helps glucose from food enter the cells, providing them with energy. When diabetes is present, it leads to elevated levels of glucose in the blood, which can cause serious health complications if left unmanaged. There are primarily two types: Type 1 diabetes, which is an autoimmune condition where the body attacks insulin-producing cells, and Type 2 diabetes, which is often associated with lifestyle factors such as obesity and lack of physical activity, leading to insulin resistance.
Managing diabetes typically involves a combination of lifestyle changes, such as a balanced diet and regular exercise, along with monitoring blood sugar levels and, in many cases, medication or insulin therapy. Education is crucial for those with diabetes to understand how their condition works and how to manage it effectively. The goal of diabetes management is to keep blood sugar levels within a target range, helping to prevent complications such as heart disease, nerve damage, and kidney failure. Regular check-ups and consultations with healthcare professionals are essential to ensure optimal care.
L-Taurine is a sulfonic acid and an amino acid often categorized as a conditionally essential amino acid due to its important roles in various bodily functions. Unlike most amino acids, L-Taurine is not used to synthesize proteins but is critical for several physiological processes, including bile salt formation, osmoregulation, and antioxidant defense. It’s naturally found in high concentrations in the brain, muscles, heart, and blood, playing a vital role in cardiovascular health and the maintenance of neurological function.
L-Taurine is often included in dietary supplements and energy drinks due to its potential benefits, such as enhancing exercise performance, improving recovery, and supporting overall energy levels. While the body can produce taurine from other amino acids like cysteine, some people may choose to supplement with it, particularly athletes or those seeking additional health benefits. As always, it's important to consult with a healthcare provider before starting any new supplement regimen to ensure safety and appropriateness for your individual health needs.
There is some emerging evidence suggesting that L-Taurine may have beneficial effects for individuals with diabetes, though it is not a cure or primary treatment. L-Taurine, an amino acid found in various foods and produced naturally in the body, has shown properties that could potentially aid in glucose regulation and improve insulin sensitivity. Some studies suggest that it can help lower blood sugar levels, reduce oxidative stress, and impact lipid metabolism positively, which could be beneficial for people managing diabetes. However, while these findings are promising, more extensive clinical trials are needed to establish definitive conclusions about its effectiveness and dosage.
It's essential for anyone considering L-Taurine supplementation to consult their healthcare provider, particularly if they have existing medical conditions like diabetes. The interaction with diabetic medications or overall metabolic health should be carefully monitored. Remember, maintaining a balanced diet, regular physical activity, and adhering to prescribed medications remain the cornerstone of diabetes management.
Users report varying timelines for noticing the benefits of taurine supplementation in managing diabetes. Some individuals have experienced improvements within a few weeks, citing enhanced energy levels and better glucose regulation in as little as one month Read Review. Others, however, have stated that it took them several months to fully appreciate the supplement's effects, including stabilizing blood sugar levels and reducing insulin resistance consistently Read Review.
Overall, the general consensus among users indicates that while some may see quicker results, achieving the full benefits of taurine supplementation often takes around one to six months, depending on individual health conditions and adherence to dosage recommendations Read Review. Users have suggested taking taurine before meals and monitoring its impact on their body to maximize effectiveness Read Review. It is advisable to be patient and consult with a healthcare professional regarding the integration of taurine into your diabetes management plan.
The scientific research supports several supplements that may have beneficial effects in managing diabetes. Notably, cornel iridoid glycosides (CIG) have been shown to significantly control metabolic disorders in type 2 diabetes models, indicating a potential for clinical application in diabetes management [1]. Furthermore, studies on specialized fermented milk products have shown improved markers for fat and carbohydrate metabolism in patients with type 2 diabetes, suggesting that dietary interventions can complement traditional diabetes therapies [2].
Additionally, taurine, an amino acid, has been consistently highlighted for its multifaceted role in diabetes management. Research indicates that taurine can improve blood sugar levels, enhance insulin sensitivity, and potentially aid in the recovery from diabetes-related complications like diabetic kidney and nerve damage [3][19]. Other studies suggest that taurine might assist in wound healing for diabetic patients and enhance the effects of standard medications like metformin, positioning it as a promising candidate for future diabetes treatment strategies [13][15]. Overall, the collective evidence points toward promising avenues for using these supplements in diabetes care.
Based on user reviews, taurine supplementation has been reported to yield a variety of benefits for individuals managing diabetes. Many users highlight improvements in blood sugar stability, with one user noting significant control over sugar surges after six months of consistent use Read Review. Others mentioned enhanced glucose metabolism and increased energy levels, which contribute positively to mood and overall health Read Review. Several users also found that taurine helped in addressing insulin resistance, making it a viable component of their diabetes management regimen Read Review.
Beyond blood sugar management, users reported additional benefits, such as improved eye health and cardiovascular support Read Review. Some have even experienced noticeable changes like reduced bile thickness and improved focus while working Read Review. However, it's important to highlight that individual results can vary significantly, and while some users notice benefits fairly quickly, others may require more time to experience similar effects. As always, it’s advisable to consult with a healthcare professional before starting any new supplement Read Review.
Users have reported positive experiences when combining taurine supplementation with other treatments for managing diabetes. For instance, some individuals have taken taurine alongside water and have noted that it effectively helps lower glucose levels and insulin resistance Read Review. Additionally, a user mentioned mixing taurine with caffeine and vitamin B for enhanced energy and cognitive function Read Review. This indicates a potential for taurine to complement other supplements and lifestyle changes effectively in a diabetes management plan.
Moreover, users have highlighted that taurine's benefits, like improved glucose metabolism and energy enhancement, make it a valuable addition to their diabetes regimens Read Review. Some feedback indicates that thorough observation of dietary practices, such as taking taurine before meals, maximized its effectiveness for blood sugar control Read Review. Overall, the integration of taurine with other supplements can yield synergistic benefits, depending on individual health conditions and adherence to recommended dosages.
Users report varying dosages for L-Taurine in managing diabetes, often recommending around 2 grams taken multiple times a day. For instance, one user mentions a regimen of taking 2 grams in the morning and another 2 grams in the evening, which they found beneficial for both reducing swelling and potentially aiding their diabetes condition Read Review. Another user advises taking Taurine before meals, which helped improve their weight loss and concentration efforts Read Review.
Overall, user feedback suggests that taking Taurine on an empty stomach may enhance its effectiveness, with many reporting positive impacts on insulin resistance and blood sugar levels when consistently included in their routines Read Review. It's noted as a safe supplement without overdose risk, making it a valuable addition for diabetes management Read Review. However, specific dosages seem to vary based on personal health preferences and experiences.
7.5
Eyesight improvement
5 people found this helpful
Taurine is crucial for heart health and diabetes management. It enhances glucose metabolism, supports eye health, and has improved my energy and mood significantly.
9
Stabilises blood sugar
52 people found this helpful
I appreciate taurine for stabilising sugars in diabetes. It prevents surges and has improved my health for six months. It does not raise blood pressure, so I take it without worry.
7.5
Insulin resistance remedy
91 people found this helpful
A good remedy for insulin resistance and diabetes. It offers excellent value for money, just like other products from NOW.
7.5
Metabolic enhancement
38 people found this helpful
Taurine prevents lipid oxidation, improves metabolic processes and lowers glucose levels in diabetics. I was advised to take it before meals, and I found it effective for weight loss and concentration.
7.5
Cognitive function support
19 people found this helpful
Taurine helps create new nerve cells and mitigates age-related cognitive decline. It supports diabetes treatment and has benefits for vision and overall stress relief.
7.5
Promotes cell regeneration
10 people found this helpful
Taurine helps with metabolism and cell regeneration, making it beneficial for diabetes-related conditions. I take it in the morning and its effects on bile thickness are noticeable.
9
Supports bile flow
11 people found this helpful
Taurine prevents bile thickening and aids in diabetes management by lowering blood pressure and reducing insulin resistance. I’ve been taking it regularly along with water and feel it's beneficial.
6
Helps energy levels
4 people found this helpful
Taurine is a conditionally essential amino acid formed from cysteine in the body. It aids the nervous system, enhances energy processes, supports tissue regeneration, and assists with cardiovascular diseases and diabetes. I've noticed my eyes feel less fatigued, making it easier to work on a computer. For energy, I mix taurine with caffeine and vitamin B.
7.5
Pressure reduction aid
Taurine effectively reduces blood pressure. I take 2 grams in the morning and 2 in the evening, which alleviates swelling without electrolyte loss. It's beneficial for the cardiovascular system and may positively affect diabetes or pre-diabetes.
7.5
Supports liver function
2 people found this helpful
Taurine is an important amino acid for our bodies with antidepressant effects, crucial for liver health and metabolism. I take taurine courses on an empty stomach before meals, finding it particularly beneficial for diabetes.
7.5
Broad health benefits
6 people found this helpful
Taurine has no overdose risk and is effective for diabetes and cardiovascular issues. It helps in fat metabolism and cholesterol reduction, making it a valuable supplement.
8
Cornel iridoid glycosides effective for diabetes
Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats.
We delved into the effects of cornel iridoid glycosides (CIG) on type 2 diabetes using a rat model. After inducing diabetes with a high-fat diet and streptozotocin, we examined various health indicators and conducted detailed metabolomic analyses of serum and urine.
Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
8
Specialized milk improves diabetes outcomes
[Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders].
We aimed to assess the benefits of a specialized fermented milk product on patients with type 2 diabetes who also experience abdominal obesity. Over 21 days, 40 patients were divided into two groups; one consumed the milk product while the other did not.
Good tolerability was noted, and both groups experienced significant weight loss and improvements in body composition. However, those who consumed the milk product showcased even greater benefits, such as increased vitamin levels and improved markers for fat and carbohydrate metabolism. Overall, this specialized product can be a helpful addition to diet therapy for those managing diabetes.
8
Anthocyanins improve kidney function
Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism.
We explored the impact of anthocyanins, specifically cyanidin-3-O-glucoside, on diabetic kidney disease (DKD). Through evaluating blood glucose and renal function, along with advanced metabolic analyses, we discovered that anthocyanins significantly reduced blood glucose levels and improved kidney function in treated mice compared to those not receiving treatment.
Our findings highlight that the benefits might stem from changes in amino acid metabolism. Incorporating dietary anthocyanins could be an effective strategy for preventing or managing DKD effectively.
9
Taurine aids spinal cord recovery
Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway.
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.
Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.
We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.
Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
8
Taurine's role in diabetes therapy
Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations.
The recent research focused on the effects of taurine, in combination with metformin and cholecalciferol (vitamin D3), on managing type 2 diabetes mellitus (T2DM) in a rat model. This interesting approach aimed to address more than just blood sugar levels, hoping to tackle related complications such as oxidative stress and inflammation.
We observed that the combination treatment showed promise in improving glycemic control and minimizing lipid issues. However, it's essential to recognize that the study does not provide a clear picture of taurine's isolated impact on diabetes, as its effects were only examined in conjunction with other substances.
Furthermore, the study was limited by a lack of safety data and detailed information about how taurine works at a molecular level. While the findings suggest potential benefits, we need to be cautious and seek further research to fully understand taurine's role and ensure its safe use in diabetes therapy.
8
Taurine may enhance diabetes outcomes
Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats.
We explored the potential of taurine supplementation alongside metformin to enhance diabetes management and reduce complications. In our study, we used a group of sixty rats, half of which were diabetic and received different treatments. Some rats got metformin only, while others received metformin with taurine, cholecalciferol (Vitamin D), or both.
Observations revealed that diabetic rats had serious metabolic issues, including high glucose and fat levels, as well as low antioxidant enzyme activity. However, those treated with metformin combined with taurine and cholecalciferol showed significant improvements. Their metabolic parameters, including insulin levels and islet mass, responded positively to the combined supplements.
The findings suggest that the combination of taurine and metformin may help in controlling diabetes better by reducing inflammation and oxidative stress. This approach could lead to a more effective management strategy for patients struggling with diabetes-related complications.
References
Hou Y, Huang Y, Shang Z, Ma S, Cui T, et al. Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats. J Ethnopharmacol. 2024;328:118065. doi:10.1016/j.jep.2024.118065
Sharafetdinov KK, Novokshanova AL, Kochetkova AA, Plotnikova OA, Alekseeva RI, et al. [Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders]. Vopr Pitan. 2024;93:67. doi:10.33029/0042-8833-2024-93-6-67-75
Li YX, Lu YP, Tang D, Hu B, Zhang ZY, et al. Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism. J Transl Med. 2022;20:510. doi:10.1186/s12967-022-03717-9
Tian J, Dang H, O'Laco KA, Song M, Tiu BC, et al. Homotaurine Treatment Enhances CD4 and CD8 Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice. Immunohorizons. 2019;3:498. doi:10.4049/immunohorizons.1900019
Zheng Y, Ceglarek U, Huang T, Wang T, Heianza Y, et al. Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. J Clin Endocrinol Metab. 2016;101:3820.
Abd El-Twab SM, Mohamed HM, Mahmoud AM. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis. Can J Physiol Pharmacol. 2016;94:651. doi:10.1139/cjpp-2015-0503
Adrian TE, Gariballa S, Parekh KA, Thomas SA, Saadi H, et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. 2012;55:2343. doi:10.1007/s00125-012-2593-2
Song MK, Salam NK, Roufogalis BD, Huang TH. Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment. Biochem Pharmacol. 2011;82:1209. doi:10.1016/j.bcp.2011.07.089
Zeng K, Xu H, Chen K, Zhu J, Zhou Y, et al. Effects of taurine on glutamate uptake and degradation in Müller cells under diabetic conditions via antioxidant mechanism. Mol Cell Neurosci. 2010;45:192. doi:10.1016/j.mcn.2010.06.010
Zeng K, Xu H, Mi M, Chen K, Zhu J, et al. Effects of taurine on glial cells apoptosis and taurine transporter expression in retina under diabetic conditions. Neurochem Res. 2010;35:1566. doi:10.1007/s11064-010-0216-1
Gaamoussi F, Israili ZH, Lyoussi B. Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats. Pak J Pharm Sci. 2010;23:212.
Wang LJ, Yu YH, Zhang LG, Wang Y, Niu N, et al. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas. Eur J Pharmacol. 2008;597:75. doi:10.1016/j.ejphar.2008.08.031
El-Akabawy G, Eid N. Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations. World J Diabetes. 2025;16:100066. doi:10.4239/wjd.v16.i1.100066
Tian S, Mei J, Zhang L, Wang S, Yuan Y, et al. Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing. Small. 2024;20:e2407340. doi:10.1002/smll.202407340
Attia MS, Ayman F, Attia MS, Yahya G, Zahra MH, et al. Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats. World J Diabetes. 2024;15:1778. doi:10.4239/wjd.v15.i8.1778
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity. Nature. 2024;633:182. doi:10.1038/s41586-024-07801-6
Yuan J, Hou Q, He X, Zhong L, Li M, et al. Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing. Int J Biol Macromol. 2024;273:132762. doi:10.1016/j.ijbiomac.2024.132762
Simões BES, Muniz MRR, Araujo TD, Magalhães Carneiro E, Simionato AVC. Evaluation of tauroursodeoxycholic acid in liver cells' cultures by MEKC: Initial hints to comprehend its role in diabetes mellitus of obese individuals. Electrophoresis. 2024;45:1252. doi:10.1002/elps.202300223
Wang Y, Gao B, Chen X, Shi X, Li S, et al. Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway. Amino Acids. 2024;56:32. doi:10.1007/s00726-024-03392-8
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. A PTER-dependent pathway of taurine metabolism linked to energy balance. bioRxiv. 2024. doi:10.1101/2024.03.21.586194
Ouyang G, Wang N, Tong J, Sun W, Yang J, et al. Alleviation of taurine on liver injury of type 2 diabetic rats by improving antioxidant and anti-inflammatory capacity. Heliyon. 2024;10:e28400. doi:10.1016/j.heliyon.2024.e28400