We explored how spirulina impacts mast cell-mediated allergic reactions. In our investigation, we found that spirulina significantly inhibited both systemic and local allergic responses in rats, completely blocking reactions induced by compound 48/80 when given in certain doses.
Additionally, we saw that spirulina reduced histamine levels and inhibited mast cell functions, which typically promote allergic reactions. These findings suggest that spirulina has a promising role in mitigating immediate-type allergies, both in laboratory settings and potentially for future practical applications.
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We investigated how peptides from Spirulina maxima might help manage allergic reactions. By testing two specific peptides, P1 and P2, on mast cells—key players in allergies—we found they significantly reduced symptoms like histamine release.
P1 worked by blocking calcium signaling, while P2 suppressed processes that typically lead to allergic responses. Overall, our findings suggest that these peptides could be effective options for developing new treatments and dietary ingredients aimed at alleviating allergies.
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Spirulina shows mild allergy reliefTherapeutic efficacy of spirulina against ovalbumin and cigarette smoke-induced asthma-specific stress biomarkers in Sprague-Dawley rats.
Moderate relevance for practical use
We explored how spirulina might help with allergic asthma by conducting a study on rats. The rats were divided into four groups, with one group receiving spirulina, while others received a standard treatment for comparison. After inducing asthma through injections, we observed that spirulina reduced certain stress biomarkers related to asthma.
Notably, spirulina lowered total cells and specific inflammatory markers in the lungs, but salbutamol—a common asthma medication—was more effective overall. While spirulina showed promise in easing mild to moderate symptoms, more research is essential for human applications.
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We explored how spirulina supplementation affects immune cells in young soccer players during their training for a tournament. In a study of 39 athletes, those who took spirulina showed a notable change in immune cell ratios compared to those who received a placebo.
While spirulina appeared to help maintain stable immune function, the placebo group experienced significant differences in their immune cells over time. These findings suggest that spirulina may enhance immunity and possibly alleviate rapid-onset allergies, although more research is needed to confirm these effects.
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We investigated how Spirulina affects antibody production related to allergies in mice. Our study revealed that while Spirulina did not increase IgE levels—associated with allergic reactions—it did enhance IgG1 and notably boosted IgA levels when given alongside an allergen. This suggests that spirulina may not worsen allergies but can help build up IgA, offering some protective benefits against allergic reactions. Overall, it seems that Spirulina extract might be a supportive option in managing food allergies without triggering further reactions.
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