' 
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
8
Recombinant proteins for allergy diagnosis
Pattern of sensitization to yellow jacket venom and expression of recombinant antigen 5 (Ves v 5) from yellow jacket venom.
High relevance to venom allergy
We explored the potential of recombinant phospholipase A5, also known as Ves v 5, to improve the diagnosis of yellow jacket venom allergies. Our study involved seven individuals, including those who had allergic reactions and those who did not. By isolating serum samples from these participants, we assessed their reactions to both bee venom and the recombinant allergens.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
Read More
8
Propofol's role in allergy reduction
Inhibitory Effect of Propofol on Type II Inflammation in Mice with Allergic Rhinitis.
Direct investigation of propofol's effects
We designed a study to explore how propofol, a widely used anesthetic, influences allergic rhinitis (AR) in mice. Using a model where mice were sensitized and challenged with ovalbumin (OVA), we observed how propofol interacts with immune cells that play a crucial role in inflammation. Our findings revealed that propofol effectively reduced the levels of certain immune cells and cytokines associated with type II inflammation.
Specifically, we noted a decrease in markers for immune cell types like eosinophils and T-helper cells, indicating a reduction in the overall inflammatory response. Interestingly, propofol treatment led to a significant drop in type II cytokines, like IL-5 and IL-13, which are typically elevated in AR.
We also saw that when CD4+ T cells and innate lymphoid cells (ILC2s) interacted, the presence of more type II cells (TH2) increased. However, introducing propofol in these co-cultures reduced the percentage of TH2 cells, suggesting it has an inhibitive effect on allergic inflammation. These results suggest that propofol might offer a new perspective in managing allergic conditions by regulating both innate and adaptive immune responses.
Specifically, we noted a decrease in markers for immune cell types like eosinophils and T-helper cells, indicating a reduction in the overall inflammatory response. Interestingly, propofol treatment led to a significant drop in type II cytokines, like IL-5 and IL-13, which are typically elevated in AR.
We also saw that when CD4+ T cells and innate lymphoid cells (ILC2s) interacted, the presence of more type II cells (TH2) increased. However, introducing propofol in these co-cultures reduced the percentage of TH2 cells, suggesting it has an inhibitive effect on allergic inflammation. These results suggest that propofol might offer a new perspective in managing allergic conditions by regulating both innate and adaptive immune responses.
Read More
7
NECs and Tregs interaction in allergies
Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.
Study highlights protein-treg communication
We explored how nasal epithelial cells (NECs) communicate with regulatory T cells (Tregs) in the context of allergic rhinitis, particularly through the protein CCL1. In our study, we used a co-culture system involving human NECs and Tregs from both allergy sufferers and healthy controls. This design allowed us to analyze the changes in chemokine expressions and surface markers after exposure to allergens.
Our results showed that Tregs expressed higher levels of certain markers after interacting with NECs than in isolation. We observed that the allergic response to the allergen Derp1 triggered increased levels of cytokines like TSLP, but surprisingly, CCL1 levels were lower in those with allergies compared to the controls.
When we examined the correlations between NEC-derived cytokines and Treg markers, we found that CCL1 and CCR8 had a positive correlation, suggesting that this pathway might play a significant role in how NECs and Tregs interact in the immune response associated with allergies. Our findings indicate that understanding this communication could be crucial for developing new treatments for allergic rhinitis, emphasizing CCL1's potential as a key player in allergy management.
Our results showed that Tregs expressed higher levels of certain markers after interacting with NECs than in isolation. We observed that the allergic response to the allergen Derp1 triggered increased levels of cytokines like TSLP, but surprisingly, CCL1 levels were lower in those with allergies compared to the controls.
When we examined the correlations between NEC-derived cytokines and Treg markers, we found that CCL1 and CCR8 had a positive correlation, suggesting that this pathway might play a significant role in how NECs and Tregs interact in the immune response associated with allergies. Our findings indicate that understanding this communication could be crucial for developing new treatments for allergic rhinitis, emphasizing CCL1's potential as a key player in allergy management.
Read More
Most Useful Reviews
0
Severe reactions noted
Would not purchase again. I typically don't write reviews, but this product caused severe reactions for both my daughter and me. We have allergies/intolerances but experienced horrible reactions with this particular product, unlike others we've tried. There were no warnings about cross-contamination, which is disappointing.
Read More
9.5
Effective for allergies
Mumtaz The quality is excellent, and the ingredients do not cause any allergies; its taste is very pleasant. I use it daily, and the size is excellent. The package lasts for two months and is beneficial for increasing iron. I find it useful for those on a diet or exercising, and I use it twice with a protein recipe and refreshing mix. Thank you.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
9
PTQX reduces allergy symptoms
PeiTuQingXin formula alleviated atopic dermatitis symptoms via inhibiting TRADD/TRAF2/RIP1 complex mediated NF-κB signaling pathway activation.
Addresses allergy therapy effectiveness
We investigated the effects of a traditional Chinese medicine formula, known as PTQX, on alleviating symptoms of atopic dermatitis, an itchy and persistent skin condition often triggered by allergens like house dust mites. In our study, we used NC/Nga mice, dividing them into groups: a control group, an allergy model group, and a PTQX-treated group, all exposed to HDM ointment.
Our findings revealed that the PTQX formula significantly eased inflammatory responses. It reduced the serum immunoglobulin E (IgE) levels by more than twofold and lowered the secretion of various inflammatory cytokines, suggesting a remarkable anti-inflammatory effect. We also observed a reduction in the proportion of Th2 cells in the lymph nodes, which are typically elevated during allergic reactions.
The mechanism of action seems to involve pathways related to NF-κB and Toll-like receptors. Specifically, proteomics analysis highlighted the downregulation of certain proteins, particularly TRADD, which leads to diminished activity of the NF-κB signaling pathway. Overall, these results suggest that PTQX may alleviate allergy symptoms by targeting a specific protein complex and suppressing inflammation effectively.
Our findings revealed that the PTQX formula significantly eased inflammatory responses. It reduced the serum immunoglobulin E (IgE) levels by more than twofold and lowered the secretion of various inflammatory cytokines, suggesting a remarkable anti-inflammatory effect. We also observed a reduction in the proportion of Th2 cells in the lymph nodes, which are typically elevated during allergic reactions.
The mechanism of action seems to involve pathways related to NF-κB and Toll-like receptors. Specifically, proteomics analysis highlighted the downregulation of certain proteins, particularly TRADD, which leads to diminished activity of the NF-κB signaling pathway. Overall, these results suggest that PTQX may alleviate allergy symptoms by targeting a specific protein complex and suppressing inflammation effectively.
Read More
8
Propofol's role in allergy reduction
Inhibitory Effect of Propofol on Type II Inflammation in Mice with Allergic Rhinitis.
Direct investigation of propofol's effects
We designed a study to explore how propofol, a widely used anesthetic, influences allergic rhinitis (AR) in mice. Using a model where mice were sensitized and challenged with ovalbumin (OVA), we observed how propofol interacts with immune cells that play a crucial role in inflammation. Our findings revealed that propofol effectively reduced the levels of certain immune cells and cytokines associated with type II inflammation.
Specifically, we noted a decrease in markers for immune cell types like eosinophils and T-helper cells, indicating a reduction in the overall inflammatory response. Interestingly, propofol treatment led to a significant drop in type II cytokines, like IL-5 and IL-13, which are typically elevated in AR.
We also saw that when CD4+ T cells and innate lymphoid cells (ILC2s) interacted, the presence of more type II cells (TH2) increased. However, introducing propofol in these co-cultures reduced the percentage of TH2 cells, suggesting it has an inhibitive effect on allergic inflammation. These results suggest that propofol might offer a new perspective in managing allergic conditions by regulating both innate and adaptive immune responses.
Specifically, we noted a decrease in markers for immune cell types like eosinophils and T-helper cells, indicating a reduction in the overall inflammatory response. Interestingly, propofol treatment led to a significant drop in type II cytokines, like IL-5 and IL-13, which are typically elevated in AR.
We also saw that when CD4+ T cells and innate lymphoid cells (ILC2s) interacted, the presence of more type II cells (TH2) increased. However, introducing propofol in these co-cultures reduced the percentage of TH2 cells, suggesting it has an inhibitive effect on allergic inflammation. These results suggest that propofol might offer a new perspective in managing allergic conditions by regulating both innate and adaptive immune responses.
Read More
8
Recombinant proteins for allergy diagnosis
Pattern of sensitization to yellow jacket venom and expression of recombinant antigen 5 (Ves v 5) from yellow jacket venom.
High relevance to venom allergy
We explored the potential of recombinant phospholipase A5, also known as Ves v 5, to improve the diagnosis of yellow jacket venom allergies. Our study involved seven individuals, including those who had allergic reactions and those who did not. By isolating serum samples from these participants, we assessed their reactions to both bee venom and the recombinant allergens.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
The production of Ves v 5 was successfully carried out in Escherichia coli, leading to the creation of soluble proteins that we then purified. We performed various tests to evaluate these proteins' functionality. This included assessing their biochemical characteristics and how well they interacted with the immune system.
Our findings highlighted the significant role of Ves v 5 in allergic reactions to hymenoptera venoms. The results suggest that recombinant proteins can be a promising alternative for diagnosing these allergies, moving away from traditional methods that rely on whole venom extracts. Ultimately, allergen-specific therapies could provide more effective and tailored treatment options for those prone to these allergies.
Read More
7
NECs and Tregs interaction in allergies
Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.
Study highlights protein-treg communication
We explored how nasal epithelial cells (NECs) communicate with regulatory T cells (Tregs) in the context of allergic rhinitis, particularly through the protein CCL1. In our study, we used a co-culture system involving human NECs and Tregs from both allergy sufferers and healthy controls. This design allowed us to analyze the changes in chemokine expressions and surface markers after exposure to allergens.
Our results showed that Tregs expressed higher levels of certain markers after interacting with NECs than in isolation. We observed that the allergic response to the allergen Derp1 triggered increased levels of cytokines like TSLP, but surprisingly, CCL1 levels were lower in those with allergies compared to the controls.
When we examined the correlations between NEC-derived cytokines and Treg markers, we found that CCL1 and CCR8 had a positive correlation, suggesting that this pathway might play a significant role in how NECs and Tregs interact in the immune response associated with allergies. Our findings indicate that understanding this communication could be crucial for developing new treatments for allergic rhinitis, emphasizing CCL1's potential as a key player in allergy management.
Our results showed that Tregs expressed higher levels of certain markers after interacting with NECs than in isolation. We observed that the allergic response to the allergen Derp1 triggered increased levels of cytokines like TSLP, but surprisingly, CCL1 levels were lower in those with allergies compared to the controls.
When we examined the correlations between NEC-derived cytokines and Treg markers, we found that CCL1 and CCR8 had a positive correlation, suggesting that this pathway might play a significant role in how NECs and Tregs interact in the immune response associated with allergies. Our findings indicate that understanding this communication could be crucial for developing new treatments for allergic rhinitis, emphasizing CCL1's potential as a key player in allergy management.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
9.5
Effective for allergies
Mumtaz The quality is excellent, and the ingredients do not cause any allergies; its taste is very pleasant. I use it daily, and the size is excellent. The package lasts for two months and is beneficial for increasing iron. I find it useful for those on a diet or exercising, and I use it twice with a protein recipe and refreshing mix. Thank you.
Read More
0
Severe reactions noted
Would not purchase again. I typically don't write reviews, but this product caused severe reactions for both my daughter and me. We have allergies/intolerances but experienced horrible reactions with this particular product, unlike others we've tried. There were no warnings about cross-contamination, which is disappointing.
Read More
