' 
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
9
YL-IPA08 shows promise against anxiety
The impact and mechanisms of YL-IPA08, a potent ligand for the translocator protein (18 kDa) on protection against LPS-induced depression and cognitive dysfunction in rodents.
Highly relevant to anxiety research
We investigated how a compound called YL-IPA08, which targets the translocator protein (TSPO), affects anxiety and cognitive function in a model of inflammation induced by lipopolysaccharide (LPS). This study incorporated a range of behavioral tests to assess anxiety-like behaviors and cognitive performance post-treatment. We also validated the use of YL-IPA08 with a TSPO antagonist to confirm that its effects were indeed connected to TSPO activation.
Our findings showed that administering YL-IPA08 significantly reduced anxiety and cognitive deficits associated with LPS treatment. Moreover, it was evident that YL-IPA08 notably affected the behavior of microglia cells in the brain. We documented a decrease in inflammatory responses and increased levels of beneficial factors necessary for mental health, indicating a robust protective effect against LPS-induced conditions.
Importantly, using a TGF-β1 inhibitor demonstrated that the anti-anxiety and cognitive benefits of YL-IPA08 are partly driven through this pathway. Thus, by targeting TSPO, YL-IPA08 offers a potential therapeutic avenue for managing anxiety and cognitive dysfunction caused by inflammation.
Our findings showed that administering YL-IPA08 significantly reduced anxiety and cognitive deficits associated with LPS treatment. Moreover, it was evident that YL-IPA08 notably affected the behavior of microglia cells in the brain. We documented a decrease in inflammatory responses and increased levels of beneficial factors necessary for mental health, indicating a robust protective effect against LPS-induced conditions.
Importantly, using a TGF-β1 inhibitor demonstrated that the anti-anxiety and cognitive benefits of YL-IPA08 are partly driven through this pathway. Thus, by targeting TSPO, YL-IPA08 offers a potential therapeutic avenue for managing anxiety and cognitive dysfunction caused by inflammation.
Read More
9
ACTH alleviates anxiety post-seizures
Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures.
Directly addresses ACTH's effects
We explored the effects of Adrenocorticotropic hormone (ACTH) on anxiety-like behaviors resulting from early life seizures. This study investigates whether ACTH can help reduce anxiety in individuals who have experienced such seizures, particularly through its interaction with melanocortin 4 receptors (MC4R) in the brain.
Our findings indicate that ACTH can indeed alleviate anxiety without impacting the frequency of seizures in healthy mice, but this was not observed in those lacking the MC4R. Interestingly, when MC4R was reintroduced in either neurons or astrocytes, we saw that ACTH effectively rescued these anxiety-like behaviors.
Furthermore, we discovered that ACTH plays a role in normalizing important proteins in astrocytes, which are crucial for brain health. These results point to a new understanding of ACTH’s benefits, suggesting that it can reach beyond just managing seizures to also tackle associated psychiatric issues like anxiety.
Overall, our research emphasizes the potential of targeting MC4R with ACTH as a promising approach for treating anxiety tied to early life seizures, reshaping how we view the hormone's role in both seizure management and mental health.
Our findings indicate that ACTH can indeed alleviate anxiety without impacting the frequency of seizures in healthy mice, but this was not observed in those lacking the MC4R. Interestingly, when MC4R was reintroduced in either neurons or astrocytes, we saw that ACTH effectively rescued these anxiety-like behaviors.
Furthermore, we discovered that ACTH plays a role in normalizing important proteins in astrocytes, which are crucial for brain health. These results point to a new understanding of ACTH’s benefits, suggesting that it can reach beyond just managing seizures to also tackle associated psychiatric issues like anxiety.
Overall, our research emphasizes the potential of targeting MC4R with ACTH as a promising approach for treating anxiety tied to early life seizures, reshaping how we view the hormone's role in both seizure management and mental health.
Read More
8
Nutrition and probiotics in dialysis
Psychobiotic Protection of Nutritional Supplements and Probiotics in Patients Undergoing Hemodialysis: A Randomized Trial.
High relevance to nutritional therapy
We explored the effects of a combined oral nutritional supplement and probiotic treatment on anxiety levels in malnourished patients undergoing hemodialysis. The study involved three groups: one group received standard dietary advice, another was given the supplement with a placebo, and the last group received the supplement alongside probiotics.
Throughout the study, we collected blood and fecal samples at different intervals to measure various biomarkers related to intestinal health and mental well-being. Anxiety symptoms were assessed using the Hospital Anxiety and Depression Scale.
Our findings indicated that the group that received both the nutritional supplement and probiotics showed some improvement in depression symptoms and quality of life. However, the specific impact of protein alone on anxiety symptoms was not distinctly highlighted in the results. There was no significant evidence that focusing solely on protein treatment had a clear effect on reducing anxiety in these patients.
Throughout the study, we collected blood and fecal samples at different intervals to measure various biomarkers related to intestinal health and mental well-being. Anxiety symptoms were assessed using the Hospital Anxiety and Depression Scale.
Our findings indicated that the group that received both the nutritional supplement and probiotics showed some improvement in depression symptoms and quality of life. However, the specific impact of protein alone on anxiety symptoms was not distinctly highlighted in the results. There was no significant evidence that focusing solely on protein treatment had a clear effect on reducing anxiety in these patients.
Read More
Most Useful Reviews
8.8
Cures anxiety
The phrase, "There is no might or power except with God," serves as a remedy for ninety-nine ailments, with anxiety being the simplest among them. It was narrated by Abu Hurairah that the Messenger of God, may God's prayers and peace be upon him, said that mentioning this phrase aids in alleviating anxiety.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
9
YL-IPA08 shows promise against anxiety
The impact and mechanisms of YL-IPA08, a potent ligand for the translocator protein (18 kDa) on protection against LPS-induced depression and cognitive dysfunction in rodents.
Highly relevant to anxiety research
We investigated how a compound called YL-IPA08, which targets the translocator protein (TSPO), affects anxiety and cognitive function in a model of inflammation induced by lipopolysaccharide (LPS). This study incorporated a range of behavioral tests to assess anxiety-like behaviors and cognitive performance post-treatment. We also validated the use of YL-IPA08 with a TSPO antagonist to confirm that its effects were indeed connected to TSPO activation.
Our findings showed that administering YL-IPA08 significantly reduced anxiety and cognitive deficits associated with LPS treatment. Moreover, it was evident that YL-IPA08 notably affected the behavior of microglia cells in the brain. We documented a decrease in inflammatory responses and increased levels of beneficial factors necessary for mental health, indicating a robust protective effect against LPS-induced conditions.
Importantly, using a TGF-β1 inhibitor demonstrated that the anti-anxiety and cognitive benefits of YL-IPA08 are partly driven through this pathway. Thus, by targeting TSPO, YL-IPA08 offers a potential therapeutic avenue for managing anxiety and cognitive dysfunction caused by inflammation.
Our findings showed that administering YL-IPA08 significantly reduced anxiety and cognitive deficits associated with LPS treatment. Moreover, it was evident that YL-IPA08 notably affected the behavior of microglia cells in the brain. We documented a decrease in inflammatory responses and increased levels of beneficial factors necessary for mental health, indicating a robust protective effect against LPS-induced conditions.
Importantly, using a TGF-β1 inhibitor demonstrated that the anti-anxiety and cognitive benefits of YL-IPA08 are partly driven through this pathway. Thus, by targeting TSPO, YL-IPA08 offers a potential therapeutic avenue for managing anxiety and cognitive dysfunction caused by inflammation.
Read More
9
ACTH alleviates anxiety post-seizures
Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures.
Directly addresses ACTH's effects
We explored the effects of Adrenocorticotropic hormone (ACTH) on anxiety-like behaviors resulting from early life seizures. This study investigates whether ACTH can help reduce anxiety in individuals who have experienced such seizures, particularly through its interaction with melanocortin 4 receptors (MC4R) in the brain.
Our findings indicate that ACTH can indeed alleviate anxiety without impacting the frequency of seizures in healthy mice, but this was not observed in those lacking the MC4R. Interestingly, when MC4R was reintroduced in either neurons or astrocytes, we saw that ACTH effectively rescued these anxiety-like behaviors.
Furthermore, we discovered that ACTH plays a role in normalizing important proteins in astrocytes, which are crucial for brain health. These results point to a new understanding of ACTH’s benefits, suggesting that it can reach beyond just managing seizures to also tackle associated psychiatric issues like anxiety.
Overall, our research emphasizes the potential of targeting MC4R with ACTH as a promising approach for treating anxiety tied to early life seizures, reshaping how we view the hormone's role in both seizure management and mental health.
Our findings indicate that ACTH can indeed alleviate anxiety without impacting the frequency of seizures in healthy mice, but this was not observed in those lacking the MC4R. Interestingly, when MC4R was reintroduced in either neurons or astrocytes, we saw that ACTH effectively rescued these anxiety-like behaviors.
Furthermore, we discovered that ACTH plays a role in normalizing important proteins in astrocytes, which are crucial for brain health. These results point to a new understanding of ACTH’s benefits, suggesting that it can reach beyond just managing seizures to also tackle associated psychiatric issues like anxiety.
Overall, our research emphasizes the potential of targeting MC4R with ACTH as a promising approach for treating anxiety tied to early life seizures, reshaping how we view the hormone's role in both seizure management and mental health.
Read More
8
Nutrition and probiotics in dialysis
Psychobiotic Protection of Nutritional Supplements and Probiotics in Patients Undergoing Hemodialysis: A Randomized Trial.
High relevance to nutritional therapy
We explored the effects of a combined oral nutritional supplement and probiotic treatment on anxiety levels in malnourished patients undergoing hemodialysis. The study involved three groups: one group received standard dietary advice, another was given the supplement with a placebo, and the last group received the supplement alongside probiotics.
Throughout the study, we collected blood and fecal samples at different intervals to measure various biomarkers related to intestinal health and mental well-being. Anxiety symptoms were assessed using the Hospital Anxiety and Depression Scale.
Our findings indicated that the group that received both the nutritional supplement and probiotics showed some improvement in depression symptoms and quality of life. However, the specific impact of protein alone on anxiety symptoms was not distinctly highlighted in the results. There was no significant evidence that focusing solely on protein treatment had a clear effect on reducing anxiety in these patients.
Throughout the study, we collected blood and fecal samples at different intervals to measure various biomarkers related to intestinal health and mental well-being. Anxiety symptoms were assessed using the Hospital Anxiety and Depression Scale.
Our findings indicated that the group that received both the nutritional supplement and probiotics showed some improvement in depression symptoms and quality of life. However, the specific impact of protein alone on anxiety symptoms was not distinctly highlighted in the results. There was no significant evidence that focusing solely on protein treatment had a clear effect on reducing anxiety in these patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Cures anxiety
The phrase, "There is no might or power except with God," serves as a remedy for ninety-nine ailments, with anxiety being the simplest among them. It was narrated by Abu Hurairah that the Messenger of God, may God's prayers and peace be upon him, said that mentioning this phrase aids in alleviating anxiety.
Read More
