' 
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
9
FGF20 enhances gut barrier function
Fibroblast Growth Factor 20 Attenuates Colitis by Restoring Impaired Intestinal Epithelial Barrier Integrity and Modulating Macrophage Polarization via S100A9 in an NF-κB Dependent Manner.
Direct study on protein treatment
We analyzed the effects of Fibroblast Growth Factor 20 (FGF20) on ulcerative colitis, a chronic inflammatory condition of the digestive tract. Through experiments with mice and analysis of patient data, we discovered that FGF20 plays a key role in enhancing intestinal health.
Specifically, we observed that levels of FGF20 were significantly higher in the colons of patients and mice suffering from colitis. When FGF20 was absent, the condition worsened. However, replenishing FGF20 notably improved conditions by restoring the intestinal barrier and reducing harmful immune responses, particularly by modulating the activity of a protein called S100A9.
Furthermore, we demonstrated that FGF20 influences the inflammatory response through the NF-κB signaling pathway, thus highlighting its potential as a therapeutic target for treating ulcerative colitis. Our findings suggest that enhancing FGF20 activity could be a promising strategy in managing this debilitating condition.
Specifically, we observed that levels of FGF20 were significantly higher in the colons of patients and mice suffering from colitis. When FGF20 was absent, the condition worsened. However, replenishing FGF20 notably improved conditions by restoring the intestinal barrier and reducing harmful immune responses, particularly by modulating the activity of a protein called S100A9.
Furthermore, we demonstrated that FGF20 influences the inflammatory response through the NF-κB signaling pathway, thus highlighting its potential as a therapeutic target for treating ulcerative colitis. Our findings suggest that enhancing FGF20 activity could be a promising strategy in managing this debilitating condition.
Read More
9
DFATs-Exos enhance wound healing
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Effective exosome therapy demonstrated.
We explored the potential of using exosomes derived from dedifferentiated fat cells, known as DFATs-Exos, for enhancing the healing of diabetic wounds. In our study, we treated endothelial cells and fibroblasts with these exosomes to see how they might help in wound recovery.
By focusing on the Wnt/β-catenin signaling pathway, we observed that DFATs-Exos significantly promoted the growth of new blood vessels and improved the ability of cells to grow and move, which is crucial for proper wound healing. For our in vivo tests, we encapsulated the DFAT-Exos in GelMA hydrogel and applied it to wounds in a diabetic animal model.
The results were promising; the combination of DFATs-Exos and GelMA not only accelerated wound closure but also enhanced the quality of the collagen formed in the healing tissue. This suggests that these exosomes activate important pathways that support and expedite the healing process.
By focusing on the Wnt/β-catenin signaling pathway, we observed that DFATs-Exos significantly promoted the growth of new blood vessels and improved the ability of cells to grow and move, which is crucial for proper wound healing. For our in vivo tests, we encapsulated the DFAT-Exos in GelMA hydrogel and applied it to wounds in a diabetic animal model.
The results were promising; the combination of DFATs-Exos and GelMA not only accelerated wound closure but also enhanced the quality of the collagen formed in the healing tissue. This suggests that these exosomes activate important pathways that support and expedite the healing process.
Read More
9
Effective MSCs for wound healing
Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization.
Relevant therapeutic application confirmed
We investigated how genetically modified mesenchymal stem cells (MSCs) can impact diabetic wound healing, particularly focusing on their ability to produce certain anti-inflammatory proteins. By creating MSCs that overexpress three key anti-inflammatory factors—interleukin (IL)-4, IL-10, and IL-13—we aimed to see if these changes would help repair diabetic foot ulcers (DFUs).
Our study included various assessments, such as cell assays and wound healing evaluations, to explore how these modified cells could manage inflammation and encourage the healing process. We discovered that our genetically engineered MSCs significantly enhanced the rate of diabetic wound healing compared to the unmodified cells.
Additionally, the presence of the anti-inflammatory proteins appeared to aid in shifting the behavior of inflammation-related cells to a more healing-oriented state. Importantly, our findings also suggested these modified MSCs were safe for potential therapeutic use, marking a promising avenue in treating complications arising from diabetes.
In conclusion, our research supports the idea that using MSCs engineered to boost anti-inflammatory proteins can provide an innovative, effective solution for enhancing healing in diabetic wounds.
Our study included various assessments, such as cell assays and wound healing evaluations, to explore how these modified cells could manage inflammation and encourage the healing process. We discovered that our genetically engineered MSCs significantly enhanced the rate of diabetic wound healing compared to the unmodified cells.
Additionally, the presence of the anti-inflammatory proteins appeared to aid in shifting the behavior of inflammation-related cells to a more healing-oriented state. Importantly, our findings also suggested these modified MSCs were safe for potential therapeutic use, marking a promising avenue in treating complications arising from diabetes.
In conclusion, our research supports the idea that using MSCs engineered to boost anti-inflammatory proteins can provide an innovative, effective solution for enhancing healing in diabetic wounds.
Read More
Most Useful Reviews
8.8
Boosts immunity
High quality with excellent natural ingredients and a pleasant aroma. It acts as an antibiotic and anti-inflammatory, raising immunity and aiding in the removal of ulcers. The taste is somewhat pungent, yet it's highly beneficial for illness and a sore throat. I will certainly buy it again and recommend it due to its ease of use and suitability for a good diet.
Read More
Most Recommended Products for Ulcer
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
9
Effective MSCs for wound healing
Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization.
Relevant therapeutic application confirmed
We investigated how genetically modified mesenchymal stem cells (MSCs) can impact diabetic wound healing, particularly focusing on their ability to produce certain anti-inflammatory proteins. By creating MSCs that overexpress three key anti-inflammatory factors—interleukin (IL)-4, IL-10, and IL-13—we aimed to see if these changes would help repair diabetic foot ulcers (DFUs).
Our study included various assessments, such as cell assays and wound healing evaluations, to explore how these modified cells could manage inflammation and encourage the healing process. We discovered that our genetically engineered MSCs significantly enhanced the rate of diabetic wound healing compared to the unmodified cells.
Additionally, the presence of the anti-inflammatory proteins appeared to aid in shifting the behavior of inflammation-related cells to a more healing-oriented state. Importantly, our findings also suggested these modified MSCs were safe for potential therapeutic use, marking a promising avenue in treating complications arising from diabetes.
In conclusion, our research supports the idea that using MSCs engineered to boost anti-inflammatory proteins can provide an innovative, effective solution for enhancing healing in diabetic wounds.
Our study included various assessments, such as cell assays and wound healing evaluations, to explore how these modified cells could manage inflammation and encourage the healing process. We discovered that our genetically engineered MSCs significantly enhanced the rate of diabetic wound healing compared to the unmodified cells.
Additionally, the presence of the anti-inflammatory proteins appeared to aid in shifting the behavior of inflammation-related cells to a more healing-oriented state. Importantly, our findings also suggested these modified MSCs were safe for potential therapeutic use, marking a promising avenue in treating complications arising from diabetes.
In conclusion, our research supports the idea that using MSCs engineered to boost anti-inflammatory proteins can provide an innovative, effective solution for enhancing healing in diabetic wounds.
Read More
9
FGF20 enhances gut barrier function
Fibroblast Growth Factor 20 Attenuates Colitis by Restoring Impaired Intestinal Epithelial Barrier Integrity and Modulating Macrophage Polarization via S100A9 in an NF-κB Dependent Manner.
Direct study on protein treatment
We analyzed the effects of Fibroblast Growth Factor 20 (FGF20) on ulcerative colitis, a chronic inflammatory condition of the digestive tract. Through experiments with mice and analysis of patient data, we discovered that FGF20 plays a key role in enhancing intestinal health.
Specifically, we observed that levels of FGF20 were significantly higher in the colons of patients and mice suffering from colitis. When FGF20 was absent, the condition worsened. However, replenishing FGF20 notably improved conditions by restoring the intestinal barrier and reducing harmful immune responses, particularly by modulating the activity of a protein called S100A9.
Furthermore, we demonstrated that FGF20 influences the inflammatory response through the NF-κB signaling pathway, thus highlighting its potential as a therapeutic target for treating ulcerative colitis. Our findings suggest that enhancing FGF20 activity could be a promising strategy in managing this debilitating condition.
Specifically, we observed that levels of FGF20 were significantly higher in the colons of patients and mice suffering from colitis. When FGF20 was absent, the condition worsened. However, replenishing FGF20 notably improved conditions by restoring the intestinal barrier and reducing harmful immune responses, particularly by modulating the activity of a protein called S100A9.
Furthermore, we demonstrated that FGF20 influences the inflammatory response through the NF-κB signaling pathway, thus highlighting its potential as a therapeutic target for treating ulcerative colitis. Our findings suggest that enhancing FGF20 activity could be a promising strategy in managing this debilitating condition.
Read More
9
DFATs-Exos enhance wound healing
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Effective exosome therapy demonstrated.
We explored the potential of using exosomes derived from dedifferentiated fat cells, known as DFATs-Exos, for enhancing the healing of diabetic wounds. In our study, we treated endothelial cells and fibroblasts with these exosomes to see how they might help in wound recovery.
By focusing on the Wnt/β-catenin signaling pathway, we observed that DFATs-Exos significantly promoted the growth of new blood vessels and improved the ability of cells to grow and move, which is crucial for proper wound healing. For our in vivo tests, we encapsulated the DFAT-Exos in GelMA hydrogel and applied it to wounds in a diabetic animal model.
The results were promising; the combination of DFATs-Exos and GelMA not only accelerated wound closure but also enhanced the quality of the collagen formed in the healing tissue. This suggests that these exosomes activate important pathways that support and expedite the healing process.
By focusing on the Wnt/β-catenin signaling pathway, we observed that DFATs-Exos significantly promoted the growth of new blood vessels and improved the ability of cells to grow and move, which is crucial for proper wound healing. For our in vivo tests, we encapsulated the DFAT-Exos in GelMA hydrogel and applied it to wounds in a diabetic animal model.
The results were promising; the combination of DFATs-Exos and GelMA not only accelerated wound closure but also enhanced the quality of the collagen formed in the healing tissue. This suggests that these exosomes activate important pathways that support and expedite the healing process.
Read More
8
Synergistic treatment for diabetic ulcers
Innovative treatment of diabetic ulcers: combining chemical debridement and xenograft applications: a case study.
Mixed protein treatment impact
We explored the effectiveness of combining a unique treatment method for a tough-to-heal diabetic ulcer in a 57-year-old woman. The patient had a non-healing lower extremity diabetic ulcer (LEDU) complicated by poorly managed diabetes, making the healing process even more challenging.
Initially, standard treatments like dressings and sharp debridement didn’t work. This prompted a switch to a new approach that included using a topical chemical debriding agent, which helped to prepare the wound bed by breaking down dead tissue and destroying harmful bacteria. This agent contained methanesulfonic acid, which effectively reduced the components hindering healing.
Following this, we applied an ovine forestomach matrix graft enriched with hyaluronic acid, which we reapplied every 12 days. Over a period of 110 days, we observed significant improvement in the healing process of the ulcer. The combination of chemical debridement and grafts highlighted how protein, specifically in the form of hyaluronic acid, plays a vital role in aiding recovery. While the specific effects of the protein on its own are less clear, its incorporation here demonstrates promising potential for treating difficult wounds.
Initially, standard treatments like dressings and sharp debridement didn’t work. This prompted a switch to a new approach that included using a topical chemical debriding agent, which helped to prepare the wound bed by breaking down dead tissue and destroying harmful bacteria. This agent contained methanesulfonic acid, which effectively reduced the components hindering healing.
Following this, we applied an ovine forestomach matrix graft enriched with hyaluronic acid, which we reapplied every 12 days. Over a period of 110 days, we observed significant improvement in the healing process of the ulcer. The combination of chemical debridement and grafts highlighted how protein, specifically in the form of hyaluronic acid, plays a vital role in aiding recovery. While the specific effects of the protein on its own are less clear, its incorporation here demonstrates promising potential for treating difficult wounds.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Boosts immunity
High quality with excellent natural ingredients and a pleasant aroma. It acts as an antibiotic and anti-inflammatory, raising immunity and aiding in the removal of ulcers. The taste is somewhat pungent, yet it's highly beneficial for illness and a sore throat. I will certainly buy it again and recommend it due to its ease of use and suitability for a good diet.
Read More
