Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.8
USERS' SCORE
Good
Based on 13 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Selenium (elemental)(from 40 mg L-Selenomethionine)
200 mcg
364%
Top Medical Research Studies
8
Selenium aids gestational diabetes management
We explored whether selenium supplementation could improve blood glucose levels in pregnant women with gestational diabetes. In this randomized controlled trial conducted at an Istanbul university, women diagnosed with gestational diabetes received either diet alone or diet plus 200 µg of selenium daily for four weeks.
Findings showed that pregnant women had lower selenium levels compared to healthy counterparts. Those taking selenium experienced a more significant decrease in blood sugar levels than those on diet alone, indicating a beneficial effect of selenium on managing gestational diabetes.
Findings showed that pregnant women had lower selenium levels compared to healthy counterparts. Those taking selenium experienced a more significant decrease in blood sugar levels than those on diet alone, indicating a beneficial effect of selenium on managing gestational diabetes.
Read More
9
Antidiabetic effects of selenium
We investigated the impact of a novel selenylated low molecular weight apple pectin on diabetes management. The study focused on mice induced with type 2 diabetes through a high-fat diet and streptozotocin treatment.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Read More
9
Selenium polysaccharides aid diabetes management
We explored the effects of selenium polysaccharides derived from sweet corn cob on type 2 diabetes (T2D) through a combination of laboratory tests and animal studies. The goal was to determine how this unique compound could influence blood sugar levels in those dealing with T2D.
Our findings indicated that selenium polysaccharides help regulate enzymes that break down carbohydrates, specifically α-amylase and α-glucosidase, which play a significant role in digesting sugars. By inhibiting these enzymes, the compound appears to reduce sugar absorption into the bloodstream.
In animal models, we observed that selenium polysaccharides not only curbed blood sugar spikes but also significantly altered various metabolic pathways, impacting substances like adenine and others linked to energy and lipid metabolism. Additionally, when we compared selenium polysaccharides to a common diabetes medication, metformin, we found that the polysaccharides provided more effective metabolic interventions.
Overall, our study suggests that selenium-treated polysaccharides could play a meaningful role in managing T2D and reducing its complications while improving blood glucose levels.
Our findings indicated that selenium polysaccharides help regulate enzymes that break down carbohydrates, specifically α-amylase and α-glucosidase, which play a significant role in digesting sugars. By inhibiting these enzymes, the compound appears to reduce sugar absorption into the bloodstream.
In animal models, we observed that selenium polysaccharides not only curbed blood sugar spikes but also significantly altered various metabolic pathways, impacting substances like adenine and others linked to energy and lipid metabolism. Additionally, when we compared selenium polysaccharides to a common diabetes medication, metformin, we found that the polysaccharides provided more effective metabolic interventions.
Overall, our study suggests that selenium-treated polysaccharides could play a meaningful role in managing T2D and reducing its complications while improving blood glucose levels.
Read More
Most Useful Reviews
9
Boosts immune system
3 people found this helpful
Selenium is vital for cancer protection and immunity against viruses. It aids pancreatic cell growth and improves glucose absorption, essential for managing diabetes by reducing insulin resistance. This mineral is best absorbed with fat-soluble vitamins A, D, and E, and it’s crucial for synthesising thyroid hormones.
Read More
9
Lowers sugar levels
Selenium is vital for diabetes patients. I've been purchasing it regularly for a friend, and I’ve noticed that their sugar levels decrease significantly with its use.
Read More
7.5
Reduces diabetes complications
The price is good, and the quantity is excellent. This product offers numerous benefits: it acts as an anti-oxidant, aids digestion, supports heart health, reduces diabetes complications, and assists in the production of glutathione, a vital liver enzyme.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.8
- All Researches
9.5
Selenium nanofibers enhance wound healing
We explored how selenium-containing polyurethane nanofibers can aid in diabetic wound healing. The study developed unique nanofibers designed to tackle harmful reactive oxygen species (ROS) and inflammation, both of which impede recovery.
These nanofibers demonstrated excellent ability to reduce ROS levels, leading to remarkable healing results—showing up to 92% improvement within 14 days. Additionally, they maintained high cell viability, indicating safety. Overall, this innovative approach could significantly enhance treatment for diabetic wounds.
These nanofibers demonstrated excellent ability to reduce ROS levels, leading to remarkable healing results—showing up to 92% improvement within 14 days. Additionally, they maintained high cell viability, indicating safety. Overall, this innovative approach could significantly enhance treatment for diabetic wounds.
Read More
9.5
Effective hydrogel for diabetic wounds
We investigated the effectiveness of a new hydrogel designed for diabetic wound healing, made from oxidized hydroxyethyl cellulose (OHEC) and chitosan with selenium nanoparticles.
This hydrogel demonstrated impressive properties, including superior antioxidant and antibacterial abilities, which contribute to faster wound healing.
Our findings showed a remarkable 100% wound closure in laboratory tests within 12 hours and almost complete healing in animal models within 14 days.
Overall, this study highlights the hydrogel's multifunctional benefits, making it a promising option for treating chronic and infected wounds.
This hydrogel demonstrated impressive properties, including superior antioxidant and antibacterial abilities, which contribute to faster wound healing.
Our findings showed a remarkable 100% wound closure in laboratory tests within 12 hours and almost complete healing in animal models within 14 days.
Overall, this study highlights the hydrogel's multifunctional benefits, making it a promising option for treating chronic and infected wounds.
Read More
9
We sought to understand how selenium, when combined with taxifolin, might improve treatment options for diabetes mellitus. The focus was on creating selenized liposomes, or Tax-Se@LPs, that would enhance the delivery and effectiveness of taxifolin, a natural compound known for its potential health benefits.
Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.
Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.
Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
Read More
9
Selenium's Role in Diabetes Control
We investigated how selenium-modified peptides affect the aggregation of the human islet amyloid polypeptide (hIAPP), which is known to have a role in diabetes. Our study focused on the active peptide derived from coix seed prolamins called LPFYPN (LP6) and its modified versions.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
Read More
9
Antidiabetic effects of selenium
We investigated the impact of a novel selenylated low molecular weight apple pectin on diabetes management. The study focused on mice induced with type 2 diabetes through a high-fat diet and streptozotocin treatment.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Boosts immune system
3 people found this helpful
Selenium is vital for cancer protection and immunity against viruses. It aids pancreatic cell growth and improves glucose absorption, essential for managing diabetes by reducing insulin resistance. This mineral is best absorbed with fat-soluble vitamins A, D, and E, and it’s crucial for synthesising thyroid hormones.
Read More
9
Lowers sugar levels
Selenium is vital for diabetes patients. I've been purchasing it regularly for a friend, and I’ve noticed that their sugar levels decrease significantly with its use.
Read More
7.5
Reduces diabetes complications
The price is good, and the quantity is excellent. This product offers numerous benefits: it acts as an anti-oxidant, aids digestion, supports heart health, reduces diabetes complications, and assists in the production of glutathione, a vital liver enzyme.
Read More
7.5
Supports diabetes treatment
52 people found this helpful
I honestly appreciate Dr. Berg's advice. Selenium boasts numerous benefits: it's an anti-oxidant, aids digestion, promotes heart health, and reduces diabetes complications. It also boosts glutathione production, supports liver enzymes, and benefits skin pigmentation and thyroid function. It helps remove mercury from the body and can reduce male infertility risks. I take it daily after meals, and with prolonged use, I've felt stronger and more energised.
Read More
7.5
Enhances energy levels
34 people found this helpful
Selenium offers many benefits, including aiding digestion, promoting heart health, and reducing diabetes complications. It also supports glutathione production and helps with thyroid function. I use it daily after meals to expel toxins, and I feel energised with regular use. May God bless everyone who seeks to earn.
Read More
Frequently Asked Questions
9
Good blood sugar control
I purchased this for my mother, who is 77 and has diabetes. An article by nutritionist Teacher Liang indicated that selenium can help lower blood sugar, prompting my choice of this product. She believes it works very well, maintaining her blood sugar effectively.
7.5
Supports diabetes management
As someone with type 2 diabetes, I found that my endocrinologist recommended vitamins containing selenium. I opted to take it separately since it’s less present in complexes. I consume selenium for a month every six months and hope to see positive results.
9
Boosts immune system
3 people found this helpful
Selenium is vital for cancer protection and immunity against viruses. It aids pancreatic cell growth and improves glucose absorption, essential for managing diabetes by reducing insulin resistance. This mineral is best absorbed with fat-soluble vitamins A, D, and E, and it’s crucial for synthesising thyroid hormones.
9
Lowers sugar levels
Selenium is vital for diabetes patients. I've been purchasing it regularly for a friend, and I’ve noticed that their sugar levels decrease significantly with its use.
7.5
Improves insulin resistance
1 people found this helpful
Selenium is important for diabetes management and can improve insulin resistance, potentially reducing diabetes complications. A family member has severe diabetes, and I'm hopeful that selenium will be beneficial for their condition.
7.5
Supports diabetes treatment
52 people found this helpful
I honestly appreciate Dr. Berg's advice. Selenium boasts numerous benefits: it's an anti-oxidant, aids digestion, promotes heart health, and reduces diabetes complications. It also boosts glutathione production, supports liver enzymes, and benefits skin pigmentation and thyroid function. It helps remove mercury from the body and can reduce male infertility risks. I take it daily after meals, and with prolonged use, I've felt stronger and more energised.
7.5
Reduces diabetes complications
6 people found this helpful
Selenium combined with Q10 (200mg daily) can lower fructosamine and may prevent cardiovascular diseases in the elderly, especially for those with heart disease and type 2 diabetes. Testing for blood selenium levels is crucial; excess selenium can be harmful. I recommend this combination for anyone over 65.
8
We explored the potential of selenium nanoparticles (SeNPs) derived from the South African plant Aspalathus linearis in managing diabetes and inflammation. Focusing on their unique properties, we synthesized SeNPs using a green approach, which is both innovative and sustainable.
In our examination, we utilized various assays to evaluate their effects on diabetes and inflammation. Our findings revealed that these green-synthesized nanoparticles demonstrated a clear anti-diabetic action by inhibiting key enzymes linked to sugar metabolism. Furthermore, they also exhibited concentration-dependent anti-inflammatory properties, indicating a dual benefit.
Importantly, we confirmed the biocompatibility of SeNPs through a brine shrimp lethality assay, highlighting their safety at high concentrations. Consequently, our work suggests that these selenium nanoparticles may have significant potential in developing treatments for diabetes and related inflammatory conditions.
In our examination, we utilized various assays to evaluate their effects on diabetes and inflammation. Our findings revealed that these green-synthesized nanoparticles demonstrated a clear anti-diabetic action by inhibiting key enzymes linked to sugar metabolism. Furthermore, they also exhibited concentration-dependent anti-inflammatory properties, indicating a dual benefit.
Importantly, we confirmed the biocompatibility of SeNPs through a brine shrimp lethality assay, highlighting their safety at high concentrations. Consequently, our work suggests that these selenium nanoparticles may have significant potential in developing treatments for diabetes and related inflammatory conditions.
8
We looked into the potential benefits of selenium-containing compounds for managing diabetes, particularly focusing on type 2 diabetes mellitus (T2DM) and obesity. In this investigation, researchers designed new compounds that creatively utilized selenium through a specific strategy that modified a known chemical structure.
One of the key findings was that these new compounds were able to effectively activate a critical receptor in the body called the GLP-1 receptor. This activation led to a noticeable increase in cyclic adenosine monophosphate (cAMP), which is important for blood sugar regulation. In tests conducted on special mice designed to mimic human conditions, the compound not only lowered blood glucose levels but also reduced food intake.
Perhaps encouragingly, this compound demonstrated a longer-lasting effect compared to its predecessor, danuglipron, without showing significant adverse side effects during toxicity studies. This suggests that selenium may have a promising role in developing oral medications for T2DM and obesity, thus opening avenues for further research in this area.
One of the key findings was that these new compounds were able to effectively activate a critical receptor in the body called the GLP-1 receptor. This activation led to a noticeable increase in cyclic adenosine monophosphate (cAMP), which is important for blood sugar regulation. In tests conducted on special mice designed to mimic human conditions, the compound not only lowered blood glucose levels but also reduced food intake.
Perhaps encouragingly, this compound demonstrated a longer-lasting effect compared to its predecessor, danuglipron, without showing significant adverse side effects during toxicity studies. This suggests that selenium may have a promising role in developing oral medications for T2DM and obesity, thus opening avenues for further research in this area.
4
We explored the impact of selenium, specifically selenomethionine (SeMet), on glucose metabolism and insulin signaling pathways relevant to diabetes. The study involved several cell lines, including C2C12 muscle cells, to observe how varying concentrations of SeMet would influence key metabolic processes.
Our findings indicated that higher selenium levels may complicate glucose metabolism. For instance, in muscle cells, we noticed that after insulin stimulation, cells absorbed less glucose, suggesting a disruption in normal insulin signaling. This irregularity was reflected in the decreased expression of important proteins involved in insulin action.
We also observed that the de novo serine synthesis pathway was activated in response to elevated selenium, which could further influence glucose handling in the body. However, the effects varied notably across different cell types, with muscle cells displaying a pronounced sensitivity to selenium concentration changes.
Overall, our research highlights that excessive selenium consumption may contribute to disturbances in glucose metabolism and insulin activity, emphasizing the need for careful monitoring of selenium intake, especially for those at risk of type 2 diabetes.
Our findings indicated that higher selenium levels may complicate glucose metabolism. For instance, in muscle cells, we noticed that after insulin stimulation, cells absorbed less glucose, suggesting a disruption in normal insulin signaling. This irregularity was reflected in the decreased expression of important proteins involved in insulin action.
We also observed that the de novo serine synthesis pathway was activated in response to elevated selenium, which could further influence glucose handling in the body. However, the effects varied notably across different cell types, with muscle cells displaying a pronounced sensitivity to selenium concentration changes.
Overall, our research highlights that excessive selenium consumption may contribute to disturbances in glucose metabolism and insulin activity, emphasizing the need for careful monitoring of selenium intake, especially for those at risk of type 2 diabetes.
5
We evaluated the relationship between blood selenium levels and the functioning of insulin in people of middle and older age, particularly focusing on those without diabetes. Our study looked at two groups: middle-aged adults from the Aragon Workers Health Study, and older adults from the Seniors ENRICA study.
The results were quite revealing. We found that higher selenium levels in middle-aged individuals were linked to increased insulin resistance and heightened β-cell function. This suggests that younger adults may respond to selenium by ramping up their insulin production to compensate for resistance. However, the story changed when we looked at older adults, who did not show the same connection between selenium and β-cell function.
Essentially, our findings indicate that while selenium might initially help younger individuals cope with insulin resistance, this compensatory mechanism declines as we age. This decline raises questions about selenium's effectiveness as a treatment for insulin sensitivity in older adults, urging a closer look at individual health profiles and age-related changes.
The results were quite revealing. We found that higher selenium levels in middle-aged individuals were linked to increased insulin resistance and heightened β-cell function. This suggests that younger adults may respond to selenium by ramping up their insulin production to compensate for resistance. However, the story changed when we looked at older adults, who did not show the same connection between selenium and β-cell function.
Essentially, our findings indicate that while selenium might initially help younger individuals cope with insulin resistance, this compensatory mechanism declines as we age. This decline raises questions about selenium's effectiveness as a treatment for insulin sensitivity in older adults, urging a closer look at individual health profiles and age-related changes.
8
We explored how varying amounts of selenium supplementation affected blood sugar levels in mice with type 2 diabetes and healthy mice. Over 12 weeks, the mice received different doses, and we noticed some interesting trends. Lower doses of selenium (0.1 and 0.3 mg/kg) seemed to improve fasting blood glucose and glucose tolerance, while higher doses (0.9 and 2.7 mg/kg) worsened these conditions. This suggests that the right amount of selenium is crucial, as too much can lead to increased blood sugar and oxidative stress.
9
Selenium's Role in Diabetes Control
We investigated how selenium-modified peptides affect the aggregation of the human islet amyloid polypeptide (hIAPP), which is known to have a role in diabetes. Our study focused on the active peptide derived from coix seed prolamins called LPFYPN (LP6) and its modified versions.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
References
- Qi C, Xing H, Ding N, Feng W, Wu Y, et al. Nanometerizing Taxifolin Into Selenized Liposomes to Ameliorate Its Hypoglycemic Effect by Optimizing Drug Release and Bioavailability. Int J Nanomedicine. 2025;20:2225. doi:10.2147/IJN.S510378
- Zhang S, Sun J, Yu S, Fu T, Feng Y, et al. Molecular Observations on the Regulation of hIAPP Aggregation Process and Enhancement of Autophagy by the Short Peptide LPFYPN and Its Modified Peptides of Coix Seed Prolamins. J Agric Food Chem. 2025;73:4659. doi:10.1021/acs.jafc.4c12559
- Rodriguez-Hernandez Z, Bel-Aguilar J, Moreno-Franco B, Grau-Perez M, Redon J, et al. Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults. Nutr Diabetes. 2025;15:5. doi:10.1038/s41387-025-00361-2
- Chen X, Xu S, Yang S, Yu Z, Chen Y, et al. Discovery of Selenium-Containing Derivatives as Potent and Orally Bioavailable GLP-1R Agonists. J Med Chem. 2025;68:3386. doi:10.1021/acs.jmedchem.4c02616
- Zhan S, Huang J, Liu Y, Han F, Wang J, et al. Activation of the De Novo Serine Synthesis Pathway and Disruption of Insulin Signaling Induced by Supplemental SeMet in Vitro. Biol Trace Elem Res. 2025. doi:10.1007/s12011-024-04492-y
- Giriprasad M, Mariraj I, Rajeshkumar S, Pradeep M, Santhoshkumar J. Evaluation of antidiabetic and anti-inflammatory action of selenium nanoparticles mediated through aspalathus linearis - An in vitro study. Med J Malaysia. 2025;80:29.
- Tao W, Liu D, Guo Z, Han P, Ma Y, et al. Physicochemical properties, structural characterization, and antidiabetic activity of selenylated low molecular weight apple pectin in HFD/STZ-induced type 2 diabetic mice. Carbohydr Polym. 2025;348:122790. doi:10.1016/j.carbpol.2024.122790
- Alahmari LA, Ali LS, Fansa HA, Alshaya DS, Al-Salmi FA, et al. Antioxidant and Antiapoptotic Effects of Selenium And Nano Selenium-Loaded Exosomes on Hepatic Dysfunction of Type 1 Diabetic Rats. J Exp Zool A Ecol Integr Physiol. 2025;343:211. doi:10.1002/jez.2881
- Ibraheem O, Oyeniran OH, Ogundipe OM, Abe EO, Oyedepo TA, et al. Photo-physical characterizations and evaluation of in-vitro antioxidant, anti-inflammatory and antidiabetic potentials of green synthesized ackee (Blighia sapida) selenium nano-particles. BMC Complement Med Ther. 2024;24:392. doi:10.1186/s12906-024-04694-w
- Zeng W, Jiang S, Cun D, Huang F, Jiang Z. Tracing links between micronutrients and type 2 diabetes risk: the singular role of selenium. Front Endocrinol (Lausanne). 2024;15:1422796. doi:10.3389/fendo.2024.1422796
- Wang J, Wang X, Xiu W, Li C, Yu S, et al. Selenium polysaccharide form sweet corn cob mediated hypoglycemic effects in vitro and untargeted metabolomics study on type 2 diabetes. Int J Biol Macromol. 2024;281:136388. doi:10.1016/j.ijbiomac.2024.136388
- Ruan S, Du Y, Zhang X, Zhang X, Kang H. Ameliorative Hypoglycemic Effect of 1-DNJ via Structural Derivatization Followed by Assembly Into Selenized Nanovesicles. Int J Nanomedicine. 2025;20:4399. doi:10.2147/IJN.S516833
- Roumi Z, Kamali M, Mirshafaei MA, Torki SA, Aminnezhad B, et al. The association between type 2 diabetes and dietary antioxidant index: a cross-sectional study in the Iranian population. Arch Endocrinol Metab. 2025;68:e240170. doi:10.20945/2359-4292-2024-0170
- Ahmed W, Li S, Liang M, Peng P, Muhammad W, et al. Selenium-containing polyurethane nanofibers with MnO nanoparticles and gelsevirine promote diabetic wound healing by modulation of ROS and inflammation. Biomater Adv. 2025;173:214289. doi:10.1016/j.bioadv.2025.214289
- van der Pligt P, Wadley GD, Lee IL, Ebrahimi S, Spiteri S, et al. Antioxidant Supplementation for Management of Gestational Diabetes Mellitus in Pregnancy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Curr Nutr Rep. 2025;14:45. doi:10.1007/s13668-025-00636-1
- Yigit E, Sayar I. Selenium Supplementation and Gestational Diabetes: A Randomised Controlled Trial. J Coll Physicians Surg Pak. 2024;34:561. doi:10.29271/jcpsp.2024.05.561
- Demircan K, Chillon TS, Bang J, Gladyshev VN, Schomburg L. Selenium, diabetes, and their intricate sex-specific relationship. Trends Endocrinol Metab. 2024;35:781. doi:10.1016/j.tem.2024.03.004
- Macan TP, Magenis ML, Damiani AP, Monteiro IO, Silveira GB, et al. Brazil nut consumption reduces DNA damage in overweight type 2 diabetes mellitus patients. Mutat Res Genet Toxicol Environ Mutagen. 2024;895:503739. doi:10.1016/j.mrgentox.2024.503739
- Prasathkumar M, George A, Sadhasivam S. Influence of chitosan and hydroxyethyl cellulose modifications towards the design of cross-linked double networks hydrogel for diabetic wound healing. Int J Biol Macromol. 2024;265:130851. doi:10.1016/j.ijbiomac.2024.130851
- Karas RA, Alexeree S, Elsayed H, Attia YA. Assessment of wound healing activity in diabetic mice treated with a novel therapeutic combination of selenium nanoparticles and platelets rich plasma. Sci Rep. 2024;14:5346. doi:10.1038/s41598-024-54064-2
- Cai X, Hu Z, Zhang M, Dang Q, Yang Q, et al. Dosage-effect of selenium supplementation on blood glucose and oxidative stress in type 2 diabetes mellitus and normal mice. J Trace Elem Med Biol. 2024;83:127410. doi:10.1016/j.jtemb.2024.127410
