We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
Isotretinoin aids acne treatment
A review of isotretinoin in the treatment of frontal fibrosing alopecia.
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
Viaminate significantly improves acne
Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade.
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Read More
Most Useful Reviews
9
Fights acne
214 people found this helpful
Excellent! A beneficial vitamin for aging, dry skin, and combating acne.
Read More
7.5
Healthy skin
101 people found this helpful
Since I began taking vitamin A, my hair and nails have improved, as well as my skin, which looks healthier with reduced acne. I appreciate this effective and inexpensive vitamin and will continue using it.
Read More
9
Reduced acne
100 people found this helpful
This vitamin has significantly reduced my stress and anxiety, improved my mood, and helped me overcome migraines and acne. I highly recommend it to friends and family.
Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study.
We conducted a retrospective study to understand how vitamin A, particularly in the form of oral isotretinoin, impacts acne treatment. This powerful medication is often prescribed for severe cases of acne that don’t respond to other treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
Retinoic acid's enhanced acne treatment
Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition.
We explored the effectiveness of retinoic acid, commonly known as vitamin A, for acne treatment using a unique delivery method that combines proliposomes and nanofibers. The goal was to assess how these specially formulated nanofibers, loaded with retinoic acid, could inhibit microbial biofilm formation, a common contributor to acne.
In our study, we created various formulations of blank and retinoic acid-loaded proliposomal nanofibers. By using different ratios of polyvinylpyrrolidone, phosphatidylcholine, and cholesterol, we aimed to optimize the delivery system. Our findings showed that these formulations were able to form liposomes rapidly after hydration and had appropriate characteristics such as vesicle size and stability.
Notably, the ATRA (all-trans retinoic acid) loaded nanofibers demonstrated greater bioadhesion than a commercial cream, suggesting they may adhere better to the skin. The results indicated these nanofibers offered superior antibacterial and anti-biofilm effects compared to retinoic acid alone. This suggests that this innovative delivery method could enhance the effectiveness of vitamin A in acne treatment.
Overall, the study highlights the promising potential of combining nanofibers and liposomes to improve acne treatment outcomes, showing that vitamin A can be more effective when delivered using this advanced method.
Read More
9
Isotretinoin aids acne treatment
A review of isotretinoin in the treatment of frontal fibrosing alopecia.
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
Viaminate significantly improves acne
Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade.
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Excellent! A beneficial vitamin for aging, dry skin, and combating acne.
Read More
7.5
Healthy skin
101 people found this helpful
Since I began taking vitamin A, my hair and nails have improved, as well as my skin, which looks healthier with reduced acne. I appreciate this effective and inexpensive vitamin and will continue using it.
Read More
9
Reduced acne
100 people found this helpful
This vitamin has significantly reduced my stress and anxiety, improved my mood, and helped me overcome migraines and acne. I highly recommend it to friends and family.
Read More
9
Lighter skin
65 people found this helpful
My skin has greatly improved after taking vitamin A! It's lighter, softer, and I've noticed a significant reduction in acne. I recommend this vitamin as it also supports overall health, including skin and nail strength.
Read More
9
Sebum reduction
32 people found this helpful
I struggled with excess sebum on my face and scalp, leading to persistent scalp acne. After taking 10,000 IU of vitamin A, my sebum production decreased substantially, and my scalp acne has improved. I strongly recommend this for oily skin.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Vitamin A is a fat-soluble vitamin that's essential for several critical bodily functions, including vision, immune response, and cell differentiation. It comes in two primary forms: preformed vitamin A (retinol) found in animal products like liver, fish, and dairy, and provitamin A carotenoids, primarily found in colorful fruits and vegetables such as carrots, sweet potatoes, and spinach. The body can convert carotenoids into retinol, making these plant sources a valuable dietary option, especially for those following a vegetarian or vegan lifestyle.
Aside from its role in maintaining healthy vision—particularly in low-light conditions—vitamin A plays a significant role in skin health and the functioning of the heart, lungs, and kidneys. It also supports the immune system by promoting the development and function of white blood cells. While it's uncommon to experience a deficiency in countries where a balanced diet is accessible, a lack of vitamin A can lead to serious health problems, including night blindness and increased susceptibility to infections. In contrast, excessive intake of vitamin A, particularly through supplements, can be toxic and lead to several health issues, making it crucial to maintain a balanced intake.
Vitamin A plays a significant role in maintaining healthy skin and can be beneficial for acne treatment. It helps regulate the production of sebum, the oily substance that can clog pores and lead to acne. Additionally, vitamin A derivatives, such as retinoids, are commonly used in topical treatments to promote cell turnover, prevent follicle clogging, and reduce inflammation. These retinoids can help clear existing acne while preventing future breakouts, making them a popular choice among dermatologists.
Based on user reviews, the timeline for seeing results while taking vitamin A for acne varies, but many users report significant improvements within a few weeks to a couple of months. For instance, one user noted their acne cleared up within three weeks of starting the supplement, with visible compliments on their clear skin after one month of use Read Review. Another user experienced a clear complexion within just one week Read Review.
However, some users did see progressive improvement over a longer duration. For example, after two months, a reviewer described their skin improving significantly, with reduced acne and a healthy glow emerging Read Review. Another user shared that their overall skin health, along with acne reduction, became evident after two months of use Read Review. While results can be swift for some, it's clear that consistent use over a longer period often brings about even more pronounced improvements.
Scientific research strongly supports the use of vitamin A, particularly in the form of isotretinoin, in the treatment of acne. Numerous studies have demonstrated the effectiveness of isotretinoin in significantly reducing acne lesions and achieving remission in many patients. For instance, one study showed that isotretinoin led to a remarkable 90% reduction in lesions, with some participants experiencing complete recovery from severe acne [7]. Furthermore, isotretinoin appears to also improve related parameters like vitamin D serum levels, which can be beneficial considering the psychological and physical burdens that severe acne poses [6].
Additionally, innovative delivery methods incorporating retinoic acid can enhance the effects of vitamin A on acne. Research has focused on utilizing nanofibers and liposomal systems to effectively deliver the active component, demonstrating improved antibacterial effects and better skin adherence compared to traditional creams [3]. Overall, while vitamin A shows great promise in treating acne, individual responses to treatments may vary, underscoring the necessity for personalized medical advice when considering this therapy [5].
Based on user reviews, many individuals report notable improvements in their skin health, particularly concerning acne and overall skin appearance. For example, several users mention experiencing clearer skin and reduced acne after starting vitamin A. One reviewer highlighted a significant change within three weeks, stating their acne cleared up, leading to numerous compliments on their skin Read Review. Others have shared similar sentiments, indicating transformations such as lighter and softer skin while effectively managing oily skin and acne breakouts Read Review.
In addition to acne improvement, users have reported enhanced overall skin health and moisture balance. One reviewer noted an improvement in their complexion after months of battling acne, attributing this to the vitamin's effectiveness alongside other supplements Read Review. Another mentioned a rapid healing of acne and fading scars within a week of starting the vitamin Read Review. While these experiences are promising, it's important to note that individual results can vary significantly, and consistency in usage seems key to achieving similar outcomes.
Based on user reviews, many individuals have reported positive experiences when combining vitamin A with other supplements to enhance their acne treatment. For example, one user mentioned that taking vitamin A alongside vitamins C and E led to significant skincare improvements after months of battling acne, suggesting that this combination can effectively support skin health Read Review. Another reviewer shared that their skin cleared up rapidly when using vitamin A alongside vitamin E, showing the potential benefits of such pairings for acne management Read Review.
Additionally, users have attested to the overall effectiveness of vitamin A in their routines, indicating that when combined with other remedies, it can contribute to long-lasting skin improvements. One user noted that integrating vitamin A into a comprehensive skincare regime helped achieve deep remission from acne for several months Read Review. Overall, the potential benefits of combining vitamin A with other supplements appear promising, particularly for those struggling with persistent acne and dry skin.
When it comes to treating acne with Vitamin A, isotretinoin—an oral derivative—has emerged as a powerful option particularly for severe cases unresponsive to other treatments. Research has revealed that a daily dose of around 0.75 mg/kg of isotretinoin over four months can significantly alleviate symptoms, with some patients experiencing up to a 90% reduction in lesions ([7]). Another study noted that dosages between 10-40 mg daily were effective for patients dealing with dual challenges of acne and frontal fibrosing alopecia, further attesting to the efficacy of isotretinoin in managing acne symptoms ([8]).
Aside from isotretinoin, oral vitamin A in doses between 36,000 to 500,000 IU, with a common dosage around 100,000 IU daily, has been linked to improvements in acne as well ([13]). However, it is crucial for patients to be aware of potential side effects associated with high-dose Vitamin A, such as dry skin and possible impacts on liver health, and to discuss these risks with a healthcare provider before starting treatment. Overall, while isotretinoin often proves the go-to for severe acne, carefully managed doses of Vitamin A can also play a beneficial role in treatment.
10
Rapid improvement
1 people found this helpful
My acne cleared up within three weeks of taking this quality vitamin A! After just one month, I’m receiving numerous compliments on my clear skin. I wish I had discovered this sooner after five years of fighting acne!
10
Quick results
1 people found this helpful
My skin developed acne post-40. After starting this vitamin with vitamin E, my skin cleared up within a week. I'm thrilled!
7.5
Skin improved
1011 people found this helpful
After trying various pricey creams for my acne that worsened my skin, I found Now Food’s vitamins A and E. Initially, I saw little change, but midway through the second month, my skin improved significantly—acne reduced and a healthy glow emerged. I now feel more energetic and productive. I hope my review is helpful!
9
Improved hydration
1 people found this helpful
I found Vitamin A to be beneficial for my dry skin and acne. Over two months, my skin became hydrated and soft. I highly recommend pairing it with vitamin E.
9
Lighter skin
65 people found this helpful
My skin has greatly improved after taking vitamin A! It's lighter, softer, and I've noticed a significant reduction in acne. I recommend this vitamin as it also supports overall health, including skin and nail strength.
9
Noticed improvement
2 people found this helpful
After taking this vitamin A alongside C and E, I've witnessed a significant improvement in my skin after months of battling acne. I feel it contributes effectively to my skincare routine, especially post-antibiotic treatment.
9
Healing effect
1 people found this helpful
I realised my dehydrated acne skin was due to a vitamin A deficiency. Since taking it for less than a week, my acne has started healing rapidly, and my scars have begun to fade. I'm thrilled with the results!
10
Long-lasting results
1 people found this helpful
I used this vitamin A internally to treat my acne as part of a comprehensive regime. Along with external remedies, I experienced deep remission for six months.
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
8
Effects of vitamin A on acne
Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris.
We conducted a study looking into how vitamin A, particularly in the form of isotretinoin, affects severe acne vulgaris (AV). This inflammatory skin condition can lead to both physical and emotional distress, and we aimed to understand whether vitamin A could help alleviate these symptoms.
A total of 100 patients with severe acne participated in our research, taking 0.75 mg/kg of isotretinoin daily for a span of four months. Throughout this time, we closely monitored serum vitamin D levels at three key points: before, during, and after the treatment.
Our findings indicated that although severe acne may negatively affect vitamin D synthesis, the treatment with isotretinoin leads to an increase in vitamin D serum levels. This suggests a potential benefit of vitamin A treatment in improving vitamin D status in those suffering from severe AV. However, further studies are needed to clarify the relationship between the two.
9
Retinoic acid's enhanced acne treatment
Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition.
We explored the effectiveness of retinoic acid, commonly known as vitamin A, for acne treatment using a unique delivery method that combines proliposomes and nanofibers. The goal was to assess how these specially formulated nanofibers, loaded with retinoic acid, could inhibit microbial biofilm formation, a common contributor to acne.
In our study, we created various formulations of blank and retinoic acid-loaded proliposomal nanofibers. By using different ratios of polyvinylpyrrolidone, phosphatidylcholine, and cholesterol, we aimed to optimize the delivery system. Our findings showed that these formulations were able to form liposomes rapidly after hydration and had appropriate characteristics such as vesicle size and stability.
Notably, the ATRA (all-trans retinoic acid) loaded nanofibers demonstrated greater bioadhesion than a commercial cream, suggesting they may adhere better to the skin. The results indicated these nanofibers offered superior antibacterial and anti-biofilm effects compared to retinoic acid alone. This suggests that this innovative delivery method could enhance the effectiveness of vitamin A in acne treatment.
Overall, the study highlights the promising potential of combining nanofibers and liposomes to improve acne treatment outcomes, showing that vitamin A can be more effective when delivered using this advanced method.
4
Vitamin A's variable impact on acne
Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ.
We explored the role of vitamin A, specifically its active form, all-trans retinoic acid (ATRA), in the treatment of acne. Retinoids like ATRA are known for their ability to influence skin cell growth and differentiation, which is important when it comes to managing acne.
Our findings suggest that ATRA interacts with specific receptors in the body, helping to regulate acne-related processes. By binding to retinoic acid receptors, ATRA may assist in controlling the factors that lead to acne breakouts.
It's worth noting that while retinoids show potential, effective treatments depend on various factors, including individual responses. We observed that newer modifications to retinoid compounds may enhance their efficacy in treating acne.
Overall, while vitamin A does have a role in acne treatment, the effectiveness can vary, and more research is necessary to determine the best approaches for different individuals.
9
Isotretinoin aids acne treatment
A review of isotretinoin in the treatment of frontal fibrosing alopecia.
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
8
Oral vitamin A shows acne benefits
The use of oral vitamin A in acne management: a review.
We explored the effectiveness of oral vitamin A in treating acne, particularly in light of recent accessibility issues with isotretinoin. Our review included various studies that looked into how vitamin A can serve as an alternative for patients struggling with this condition.
In our findings, we identified nine studies, including eight clinical trials and one case report. Notably, most studies showed that acne improved with vitamin A treatment, with dosages typically ranging from 36,000 to 500,000 IU, and a common dose being around 100,000 IU daily.
We noted that the average time to see improvement varied between about seven weeks to four months. While mucocutaneous side effects like dry skin were frequent, headaches also occurred but generally resolved either through continued treatment or by stopping it.
It's important to remember that like isotretinoin, vitamin A can pose risks to pregnant women, emphasizing the need for careful management during treatment. Overall, our exploration indicates that vitamin A can be an effective option for acne, though some limitations exist in the quality of available studies.
References
Abuallut II, Dibaji MQ, Assiri A, Mawkili W, Najmi AY, et al. Oral Isotretinoin-Associated Ocular Effects and Risk Factors: A Cross-Sectional Study. Clin Ophthalmol. 2024;18:4041. doi:10.2147/OPTH.S491757
Yaqoubi WSAA, Touby SSJA, Hossain MA. Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study. Toxicol Rep. 2024;13:101799. doi:10.1016/j.toxrep.2024.101799
Tort S, Öztürk ZC, Kaynak-Onurdağ F, Mutlu-Ağardan NB. Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition. Pharm Dev Technol. 2024;29:955. doi:10.1080/10837450.2024.2411034
Kulaklı S, Elmas Telli AC, Sarı İF, Oğuz ID, Kulaklı F. Increased femoral cartilage thickness in acne patients using isotretinoin: could it be a sign of early osteoarthritis?. Arch Dermatol Res. 2024;316:512. doi:10.1007/s00403-024-03264-x
Powała K, Żołek T, Brown G, Kutner A. Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ. Int J Mol Sci. 2024;25. doi:10.3390/ijms25126568
Hussein RS, Dayel SB, Abahussein O. Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris. Turk J Med Sci. 2023;53:1732. doi:10.55730/1300-0144.5742
Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4
Shahpar A, Nezhad NZ, Sahaf AS, Ahramiyanpour N. A review of isotretinoin in the treatment of frontal fibrosing alopecia. J Cosmet Dermatol. 2024;23:1956. doi:10.1111/jocd.16245
Demir EY, Köse ÖK. Effects of oral isotretinoin treatment for acne vulgaris patients on anger responses and the relationship with temperament. Rev Assoc Med Bras (1992). 2023;70:e20230592. doi:10.1590/1806-9282.20230592
Cao J, Xu M, Zhu L, Xiao S. Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade. Curr Drug Targets. 2023;24:1055. doi:10.2174/0113894501243867230928115205
Tsai MJ, Lin CY, Trousil J, Sung CT, Lee MH, et al. Proteinase K/Retinoic Acid-Loaded Cationic Liposomes as Multifunctional Anti-Acne Therapy to Disorganize Biofilm and Regulate Keratinocyte Proliferation. Int J Nanomedicine. 2023;18:3879. doi:10.2147/IJN.S416966
Gurel A, Gurel G, Fırat F, Ozgul E, Turkoglu IND, et al. Effect of systemic isotretinoin therapy on semen parameters. Ann Med. 2023;55:2207038. doi:10.1080/07853890.2023.2207038
Cook MK, Perche PO, Feldman SR. The use of oral vitamin A in acne management: a review. Dermatol Online J. 2022;28. doi:10.5070/D328559239
Cao J, Xu M, Zhu L, Xiao S. Viaminate ameliorates Propionibacterium acnes-induced acne via inhibition of the TLR2/NF-κB and MAPK pathways in rats. Naunyn Schmiedebergs Arch Pharmacol. 2023;396:1487. doi:10.1007/s00210-022-02379-0
Kontzias C, Zaino M, Feldman SR. Tretinoin 0.1% and Benzoyl Peroxide 3% Cream for the Treatment of Facial Acne Vulgaris. Ann Pharmacother. 2023;57:1088. doi:10.1177/10600280221147338
Kosmoski G, Miller D, Coret C, Atillasoy E. A Topical Combination Regimen of Benzoyl Peroxide and Retinol Moisturizer for Mild to Moderate Acne. J Drugs Dermatol. 2022;21:1340. doi:10.36849/JDD.6845