5/17/2025
Last update
5/17/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 20 Reviews
8.2
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
<1%**
Sodium
150 mg
7%
Glucosamine Sulfate(from 1,500 mg Glucosamine PotassiumSulfate Complex)
1.1 g (1,100 mg)
†
Chondroitin Sodium Sulfate(from Bovine Cartilage)
1.2 g (1,200 mg)
†
MSM (Methylsulfonylmethane)
300 mg
†
Top Medical Research Studies
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
Most Useful Reviews
9
Improved flexibility
This amazing product is for elderly people suffering from Osteoporosis. I purchased it for my mother, and it enhances cartilage and bone strength while reducing discomfort related to Osteoporosis.
Read More
9
Effective pain relief
It effectively prevents Osteoporosis and osteoarthritis. My joints do not hurt anymore after taking this medication.
Read More
9
Significant aid
I buy this for my mother, who suffers from Osteoporosis. She drinks it in courses, and it helps her significantly.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved flexibility
This amazing product is for elderly people suffering from Osteoporosis. I purchased it for my mother, and it enhances cartilage and bone strength while reducing discomfort related to Osteoporosis.
Read More
9
Effective pain relief
It effectively prevents Osteoporosis and osteoarthritis. My joints do not hurt anymore after taking this medication.
Read More
9
Significant aid
I buy this for my mother, who suffers from Osteoporosis. She drinks it in courses, and it helps her significantly.
Read More
9
Joint health support
Glucosamine Chondroitin MSM supports normal joint function, enhancing Osteoporosis management by strengthening cartilage and preventing joint degeneration.
Read More
9
Beneficial effects
2 people found this helpful
Excellent! This product is beneficial for osteoporosis.
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Frequently Asked Questions
9
Notable improvement
An excellent product for joint support in people with osteoporosis and deforming arthritis. The effect was noticeable after a week of use.
9
Enhanced joint comfort
A nutritionist recommended Glucosamine and Chondroitin plus MSM for my mother suffering from severe osteoporosis. After a few weeks of use, her joint pain decreased, and her flexibility and comfort improved, making daily activities easier.
9
Rapid improvement
I gave it to a friend with osteoporosis, and thankfully, she improved within the first month.
7.5
Reduced joint discomfort
2 people found this helpful
My 78-year-old mother has experienced no more aching joints since taking this for over a year. Though she has mild osteoporosis, she no longer complains about knee and joint pain. Along with proper nutrition and gentle exercises, this has supported healthy bone growth.
7.5
Excellent combination
This was taken for osteoporosis treatment, and when combined with vitamins, it works well. The combination is excellent, and there are enough capsules for an extended duration.
7.5
Decreased joint pain
On my doctor's advice, I take two capsules daily for knee joint issues. I've noticed decreased joint pain, reduced swelling, and the crunch has disappeared. Chondroitin is useful for fractures, arthritis, and osteoporosis, while glucosamine strengthens joints and cartilage.
9
Slowed osteoporosis development
Taking glucosamine slows the development of osteoporosis, promotes rapid cartilage recovery, and significantly reduces pain and inflammation. The product provides glucosamine that enhances joint fluid nutrition.
8
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.
Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
References
- Kim DN, Joung YH, Darvin P, Kang DY, Sp N, et al. Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells. Mol Med Rep. 2016;14:460. 10.3892/mmr.2016.5274
