Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Glutathione (Reduced Form)
500 mg
**
Milk Thistle Extract (Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)
100 mg
**
Alpha Lipoic Acid
50 mg
**

Top Medical Research Studies

9.5
Effective herbal treatment for menopause
We evaluated the effects of Silybum marianum, a herbal remedy, on menopausal symptoms, particularly hot flashes. In a well-structured study with eighty women, half were given S. marianum extract while the other half received a placebo over 12 weeks.

Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.

This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Read More
8
Silymarin shows promise for osteoporosis
We delved into the potential effects of silymarin, derived from milk thistle, on osteoporosis, which is particularly concerning for postmenopausal women. The study highlighted how silymarin could promote bone formation and aid in fracture healing by demonstrating antioxidant properties.

In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
Read More
4
Naturopathic interventions had limited effects
We investigated the effects of naturopathic botanical supplements, including silybum marianum, and dietary changes on hormone levels in premenopausal women over five menstrual cycles.

The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.

While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.

Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
Read More

Most Useful Reviews

9
Reduced hot flashes
Glutathione is amazing! It’s essential during menopause. I've been taking various supplements but felt something was lacking. I take one capsule daily, and I forget about everything—the hot flashes have disappeared. It's essential to have alanines, vitamin D3, Omega-3, soy lecithin, and magnesium during this time. I won’t elaborate on glutathione’s composition, but it contains three vital amino acids for our bodies. Buy it—you won't regret it. Stay healthy!
Read More
9
Clearer complexion
My menopausal face cleared up significantly. I’m experiencing severe menopause, and looking in the mirror used to depress me due to an increase in freckles and skin darkening. However, after continuing with glutathione, my skin became brighter and my freckles lighter. I plan to send a bottle to my son, who has skin inflammation, as I’ve been quite pleased with the results despite some mixed reviews.
Read More
7.5
Increased energy levels
2 people found this helpful
Good for menopause. I am 52 years old and in menopause. I purchased this product expecting the whitening effects of the glutathione ingredient. After two weeks of taking it, I felt lighter in the mornings. The fatigue associated with ageing has diminished. It's a relief to move with full energy from the morning. I highly recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9.5
Effective herbal treatment for menopause
We evaluated the effects of Silybum marianum, a herbal remedy, on menopausal symptoms, particularly hot flashes. In a well-structured study with eighty women, half were given S. marianum extract while the other half received a placebo over 12 weeks.

Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.

This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
Read More
9.5
Herbal formula improves menopausal symptoms
We investigated the effectiveness of the Phyto-Female Complex, a herbal blend, designed to alleviate menopausal symptoms in women aged 44-65. In a controlled trial involving 50 participants, those taking the herbal formula experienced a notable reduction in hot flushes and night sweats over three months.

By the end of the study, 47% of women in the treatment group reported no hot flushes, while only 19% in the placebo group saw similar relief. Participants also enjoyed better sleep quality, highlighting the Formula's potential as a safe option for managing menopausal discomfort.
Read More
8
Silymarin shows promise for osteoporosis
We delved into the potential effects of silymarin, derived from milk thistle, on osteoporosis, which is particularly concerning for postmenopausal women. The study highlighted how silymarin could promote bone formation and aid in fracture healing by demonstrating antioxidant properties.

In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.
Read More
4
Naturopathic interventions had limited effects
We investigated the effects of naturopathic botanical supplements, including silybum marianum, and dietary changes on hormone levels in premenopausal women over five menstrual cycles.

The study involved 40 women divided into three groups: a botanical supplement, a dietary intervention, and a placebo.

While the botanical supplement showed a decrease in certain androgens, overall, the interventions did not result in significant changes to estrogen levels.

Therefore, we conclude that silybum marianum and the investigated dietary changes have limited impacts on hormone metabolism in this context.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced hot flashes
Glutathione is amazing! It’s essential during menopause. I've been taking various supplements but felt something was lacking. I take one capsule daily, and I forget about everything—the hot flashes have disappeared. It's essential to have alanines, vitamin D3, Omega-3, soy lecithin, and magnesium during this time. I won’t elaborate on glutathione’s composition, but it contains three vital amino acids for our bodies. Buy it—you won't regret it. Stay healthy!
Read More
9
Clearer complexion
My menopausal face cleared up significantly. I’m experiencing severe menopause, and looking in the mirror used to depress me due to an increase in freckles and skin darkening. However, after continuing with glutathione, my skin became brighter and my freckles lighter. I plan to send a bottle to my son, who has skin inflammation, as I’ve been quite pleased with the results despite some mixed reviews.
Read More
7.5
Increased energy levels
2 people found this helpful
Good for menopause. I am 52 years old and in menopause. I purchased this product expecting the whitening effects of the glutathione ingredient. After two weeks of taking it, I felt lighter in the mornings. The fatigue associated with ageing has diminished. It's a relief to move with full energy from the morning. I highly recommend it!
Read More
7.5
Youthful appearance
1 people found this helpful
I'm in menopause, yet my skin has become fair and beautiful! Although it doesn’t address deep pores, my cheeks are whiter and shinier, and friends have remarked that I look younger. I also take MSM, so I believe there’s a combined effect at play.
Read More
7.5
Fewer headaches
Glutathione moisturises the skin and is beneficial for dry skin too. Since entering menopause, I’ve experienced occasional headaches, but after starting glutathione, they’ve significantly reduced. I tend to choose the cheaper option available, whether this or Jarrow. It has become a necessity for me.
Read More

Frequently Asked Questions

7.5
Increased energy levels
2 people found this helpful
Good for menopause. I am 52 years old and in menopause. I purchased this product expecting the whitening effects of the glutathione ingredient. After two weeks of taking it, I felt lighter in the mornings. The fatigue associated with ageing has diminished. It's a relief to move with full energy from the morning. I highly recommend it!
9
Reduced hot flashes
Glutathione is amazing! It’s essential during menopause. I've been taking various supplements but felt something was lacking. I take one capsule daily, and I forget about everything—the hot flashes have disappeared. It's essential to have alanines, vitamin D3, Omega-3, soy lecithin, and magnesium during this time. I won’t elaborate on glutathione’s composition, but it contains three vital amino acids for our bodies. Buy it—you won't regret it. Stay healthy!
9
Clearer complexion
My menopausal face cleared up significantly. I’m experiencing severe menopause, and looking in the mirror used to depress me due to an increase in freckles and skin darkening. However, after continuing with glutathione, my skin became brighter and my freckles lighter. I plan to send a bottle to my son, who has skin inflammation, as I’ve been quite pleased with the results despite some mixed reviews.
7.5
Fewer headaches
Glutathione moisturises the skin and is beneficial for dry skin too. Since entering menopause, I’ve experienced occasional headaches, but after starting glutathione, they’ve significantly reduced. I tend to choose the cheaper option available, whether this or Jarrow. It has become a necessity for me.
7.5
Youthful appearance
1 people found this helpful
I'm in menopause, yet my skin has become fair and beautiful! Although it doesn’t address deep pores, my cheeks are whiter and shinier, and friends have remarked that I look younger. I also take MSM, so I believe there’s a combined effect at play.
9.5
Effective herbal treatment for menopause
We evaluated the effects of Silybum marianum, a herbal remedy, on menopausal symptoms, particularly hot flashes. In a well-structured study with eighty women, half were given S. marianum extract while the other half received a placebo over 12 weeks.

Remarkably, the group taking Silybum saw a significant drop in the frequency and severity of hot flashes. Their scores on relevant scales improved notably compared to those on placebo.

This suggests that Silybum marianum could be an effective option for managing menopausal symptoms, making it a promising choice for women seeking relief.
8
Silymarin shows promise for osteoporosis
We delved into the potential effects of silymarin, derived from milk thistle, on osteoporosis, which is particularly concerning for postmenopausal women. The study highlighted how silymarin could promote bone formation and aid in fracture healing by demonstrating antioxidant properties.

In models involving fracture healing, silymarin improved bone density and markers for bone formation. It also suggested estrogen-like effects, which could help in preventing bone loss without the side effects of hormone replacement therapy. Overall, while promising, further research is needed to confirm its benefits for menopausal women.

References

  1. Saberi Z, Gorji N, Memariani Z, Moeini R, Shirafkan H, et al. Evaluation of the effect of Silybum marianum extract on menopausal symptoms: A randomized, double-blind placebo-controlled trial. Phytother Res. 2020;34:3359. doi:10.1002/ptr.6789
  2. Mohd Fozi NF, Mazlan M, Shuid AN, Isa Naina M. Milk thistle: a future potential anti-osteoporotic and fracture healing agent. Curr Drug Targets. 2013;14:1659.
  3. Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW. A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev. 2007;16:1601.
  4. Rotem C, Kaplan B. Phyto-Female Complex for the relief of hot flushes, night sweats and quality of sleep: randomized, controlled, double-blind pilot study. Gynecol Endocrinol. 2007;23:117.
image