We aimed to find out how effective a 2% green tea lotion is for treating mild-to-moderate acne. In a study involving 20 participants, the lotion was applied twice daily for six weeks.
Results showed a significant reduction in acne lesions, with total lesion counts dropping an impressive 58.33%, confirming its effectiveness. The severity of acne also notably improved.
Overall, we found that green tea lotion is a promising, cost-effective option for acne management.
Read More
9
2% tea lotion reduces acne lesions
Treatment of acne vulgaris with 2% topical tea lotion.
We explored the effectiveness of a 2% tea lotion on acne vulgaris in a study involving 60 young patients. Divided into two groups, one group used the tea lotion while the other used a control solution for two months.
The results highlighted that the tea lotion significantly reduced papules and pustules, with a notable 64% of participants reporting good treatment responses. In contrast, the control group showed minimal improvement.
Overall, this natural remedy proved to be effective and well-tolerated, offering a promising alternative for acne treatment.
Read More
9
Vitamin C shows effectiveness for acne
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Read More
Most Useful Reviews
7.5
Fewer acne noted
63 people found this helpful
Everyone knows how useful green tea is. While many prefer it brewed, in capsule form the concentration is far greater. Since starting this supplement, my mood has improved remarkably, and I feel more energetic. After the course, my skin looks clearer, and there are noticeably fewer acne. The capsules help detoxify and cleanse the liver too. If my review has helped, I would appreciate a click on YES. It’s a small effort for you but means a lot to me! Thank you!
Read More
7.5
Less acne noticed
2 people found this helpful
Everyone knows how beneficial green tea is, but not all enjoy it brewed. Capsules are a fantastic alternative as they provide a higher concentration of green tea. I’ve been using this supplement for quite some time, and whilst I don't have specific skin issues, I do believe in its efficacy. It lifts my mood, invigorates me, and after using it, my skin appears cleaner with fewer acne. This is likely due to its detoxifying properties. I hope my review proves useful!
Read More
9
Significant improvement
1 people found this helpful
I have noticed fewer acne since starting this! It has a mild scent and is easy to swallow. After a week, my skin became less oily, and my acne significantly improved. It's likely due to this version being non-decaffeinated, allowing me to enjoy it in the morning.
We aimed to find out how effective a 2% green tea lotion is for treating mild-to-moderate acne. In a study involving 20 participants, the lotion was applied twice daily for six weeks.
Results showed a significant reduction in acne lesions, with total lesion counts dropping an impressive 58.33%, confirming its effectiveness. The severity of acne also notably improved.
Overall, we found that green tea lotion is a promising, cost-effective option for acne management.
Read More
9
2% tea lotion reduces acne lesions
Treatment of acne vulgaris with 2% topical tea lotion.
We explored the effectiveness of a 2% tea lotion on acne vulgaris in a study involving 60 young patients. Divided into two groups, one group used the tea lotion while the other used a control solution for two months.
The results highlighted that the tea lotion significantly reduced papules and pustules, with a notable 64% of participants reporting good treatment responses. In contrast, the control group showed minimal improvement.
Overall, this natural remedy proved to be effective and well-tolerated, offering a promising alternative for acne treatment.
Read More
9
Vitamin C shows moderate efficacy
Efficacy of tranexamic acid solution versus vitamin C solution after micro-needling in treatment of persistent post acne erythema: a split face clinical and 3DAntera camera comparative study.
We explored the effectiveness of using vitamin C in treating persistent post-acne erythema, which often leaves visible redness after acne has cleared. In this study, participants received microneedling combined with either a 10% vitamin C solution or a tranexamic acid solution. The goal was to see which treatment worked better for reducing redness and improving overall skin appearance.
Four treatment sessions were spaced two weeks apart, followed by assessments two weeks after the final session. We measured improvements using clinical evaluations, 3D imaging technology to analyze blood flow in the skin, and patient feedback.
Our findings indicated that both treatments led to significant improvements in reducing skin redness. However, the tranexamic acid solution yielded even better results compared to vitamin C. Patients reported satisfaction on both sides, but they favored the effects of tranexamic acid more. Notably, any side effects were minimal and temporary.
This study suggests that while vitamin C can be helpful, using microneedling with tranexamic acid may deliver superior results for those struggling with post-acne redness.
Read More
9
Nutraceuticals effective for acne
Cosm-nutraceutical nanovesicles for acne treatment: Physicochemical characterization and exploratory clinical experimentation.
We aimed to understand how a novel formulation combining vitamin C and quercetin can help treat acne. Our study focused on creating small liposomal structures called aspasomes that enhance the delivery of quercetin, a potent antioxidant, onto the skin.
Throughout our research, we thoroughly characterized these aspasomes for their size, stability, and how well they could penetrate the skin. One exciting finding was that these specialized nanovesicles not only preserved the antioxidant benefits of quercetin, but also demonstrated a stronger antibacterial effect against acne-causing bacteria compared to quercetin alone.
In an exploratory clinical trial involving 20 participants with acne, we observed considerable improvements. The results revealed a 77.9% reduction in inflammatory lesions and significant decreases in both non-inflammatory lesions and total acne lesions. These findings suggest that our vitamin C-based formula holds promise in managing acne and could potentially be used for other skin conditions in the future.
Read More
9
Vitamin C reduces facial sebum
Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers.
We conducted a study to explore the effectiveness of two forms of vitamin C—ascorbyl palmitate (AP) and sodium ascorbyl phosphate (SAP)—in managing sebum production on the skin. Through a single-blinded, placebo-controlled trial involving 11 healthy female volunteers, we compared the effects of a multiple emulsion containing these compounds with a control that lacked them.
Over 90 days, participants applied the vitamin C formulation to one cheek and the control to the other. We measured sebum levels using a non-invasive device called a Sebumeter at different time intervals. Our results demonstrated that the combination of AP and SAP achieved notable antioxidant activity and effectively reduced facial oiliness compared to the control.
Ultimately, we found that incorporating vitamin C into skincare routines can be a promising solution for controlling excess facial sebum, which is often linked to oily skin and acne. However, while the study highlights the role of these antioxidants in sebum regulation, it does not provide a definitive conclusion on their isolated effects solely for acne treatment.
Everyone knows how useful green tea is. While many prefer it brewed, in capsule form the concentration is far greater. Since starting this supplement, my mood has improved remarkably, and I feel more energetic. After the course, my skin looks clearer, and there are noticeably fewer acne. The capsules help detoxify and cleanse the liver too. If my review has helped, I would appreciate a click on YES. It’s a small effort for you but means a lot to me! Thank you!
Read More
7.5
Less acne noticed
2 people found this helpful
Everyone knows how beneficial green tea is, but not all enjoy it brewed. Capsules are a fantastic alternative as they provide a higher concentration of green tea. I’ve been using this supplement for quite some time, and whilst I don't have specific skin issues, I do believe in its efficacy. It lifts my mood, invigorates me, and after using it, my skin appears cleaner with fewer acne. This is likely due to its detoxifying properties. I hope my review proves useful!
Read More
9
Significant improvement
1 people found this helpful
I have noticed fewer acne since starting this! It has a mild scent and is easy to swallow. After a week, my skin became less oily, and my acne significantly improved. It's likely due to this version being non-decaffeinated, allowing me to enjoy it in the morning.
Read More
9
Fights inflammation
Excellent! Green tea extract is known for its anti-inflammatory properties, aiding in the fight against acne and enhancing the skin's moisture. It's a fantastic way to boost your antioxidants.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Green tea extract is a concentrated form of green tea that typically contains high levels of beneficial compounds known as polyphenols, particularly catechins. These antioxidants are responsible for many of the health benefits associated with green tea, including improved metabolism, enhanced fat burning, and overall supportive effects on cardiovascular health. The extract is often available in capsules or powdered form, making it a popular supplement choice for those looking to harness the plant’s potential without having to drink multiple cups of tea each day.
In addition to its antioxidant properties, green tea extract may support weight management and provide mental clarity due to its caffeine content and L-theanine, an amino acid that promotes a state of calm alertness. As with any supplement, it's important to choose a high-quality product from reputable brands to ensure purity and potency. Users should also consult with a healthcare professional prior to adding green tea extract to their regimen, particularly if they have underlying health conditions or are taking medications.
Green tea extract has been recognized for its potential benefits in skincare, including its ability to help with acne. Rich in antioxidants, particularly catechins, green tea extract boasts anti-inflammatory properties that can reduce the redness and swelling associated with acne. Research suggests that applying green tea extract topically or incorporating it into your skincare routine may help minimize breakouts by reducing sebum production and fighting off acne-causing bacteria.
In addition, some studies indicate that oral supplementation with green tea extract could also contribute to improved skin health. However, while it may aid in managing acne for some individuals, it's important to remember that results can vary widely. It is always best to combine any supplement or topical treatment with a comprehensive skincare regimen tailored to your specific skin type. Consulting with a dermatologist can provide personalized advice and determine the most effective approach for your acne concerns.
Based on user reviews, many customers report seeing positive changes in their acne conditions after a relatively short period of use. For instance, one user mentioned that they noticed a significant improvement in their acne after just one week of taking the supplement, noting reduced oiliness and overall skin condition Read Review. Other reviewers also echoed similar sentiments, as several individuals saw their skin become clearer with fewer breakouts after a few weeks of consistent use Read Review.
In general, users seem to find that the supplement begins to show positive effects within a week to a few weeks, emphasizing its beneficial properties such as detoxification and improving overall skin health. Consistency in taking the supplement appears to be key, with several users indicating their intent to continue using it for long-term results Read Review. This suggests that while some may see initial improvements soon, enduring and continued use might be essential for optimal results.
Based on the available scientific research, certain supplements, notably green tea and vitamin C, show promise in the treatment of acne. Studies have indicated that topical applications of green tea extract can significantly reduce inflammatory lesions, demonstrating its effectiveness as an acne treatment [3]. Further evidence supports the use of green tea in various forms, including emulsions and lotions, which have led to notable reductions in acne lesions and sebum production [7], [6]. However, while oral formulations of green tea extract appear to be less effective, topical applications have shown consistent benefits [4].
Vitamin C, particularly in stable forms like sodium ascorbyl phosphate, also demonstrates potential for acne treatment through its antimicrobial properties and ability to reduce inflammation [24], [22]. Several studies highlight how vitamin C can effectively inhibit acne-causing bacteria and improve overall skin condition while being well-tolerated [23]. Overall, both green tea and vitamin C supplements could be valuable additions to acne treatment regimens, though further research is encouraged to confirm and expand upon these findings.
Based on user reviews, many individuals have reported notable improvements in their acne and overall skin health after using the green tea extract supplements. For instance, several users noted significant reductions in the number of breakouts and an overall clearer complexion within a few weeks of starting the capsules. One reviewer mentioned that after just a week, their skin became less oily, resulting in a considerable improvement in acne Read Review. Another user observed that their son experienced significantly decreased facial acne and fewer breakouts after using the product Read Review.
In addition to acne-related benefits, users also praised the supplement's overall impact on their mood and energy levels, often linking these improvements to the detoxifying properties of the product. Some users reported feeling invigorated and noted enhanced skin cleanliness and reduced inflammation Read Review. Nevertheless, it's important to recognize that individual results can vary, as some individuals are combining the supplement with other products or have different skin types and issues. However, the consensus indicates that many users found the green tea extract to be a beneficial addition to their skincare and wellness routine.
Based on user reviews, several individuals have reported favorable outcomes when combining this green tea extract supplement with other supplements in their quest to manage acne. One user mentioned improving their skin condition while also taking additional supplements, suggesting that the green tea extract complements their skincare routine effectively Read Review. This indicates that users often find it beneficial to integrate multiple products for enhanced results. However, there is no consensus on the specific combinations that work best, as experiences can vary greatly among individuals.
Users typically emphasize the effectiveness of the green tea extract alone in reducing acne and promoting clearer skin, with many noting improvements in their skin and overall well-being after starting the supplement Read Review. The detoxifying properties associated with green tea were frequently mentioned, suggesting that these benefits might be amplified when taken alongside other supplements designed to support skin health or overall wellness. However, as with any supplement regimen, it remains important to consider individual skin types and conditions for optimal results.
Based on user reviews, it appears that there is a consensus that green tea extract can effectively aid in managing acne, but specific dosage recommendations are not clearly established. Many users report positive outcomes regarding their skin condition after incorporating green tea extract into their routine. For instance, one user mentioned a noticeable reduction in acne and improved skin clarity after taking the capsules for a short period (Read Review). Another user noted fewer breakouts after starting the supplement and suggested that it helped with oiliness in their skin (Read Review).
Several users highlighted the benefits of the capsules in providing a higher concentration of green tea's active compounds, such as EGCG, which are believed to have anti-inflammatory and antioxidant properties that support acne reduction (Read Review). However, the reviews did not specify exact dosages, instead, they emphasized the effectiveness of the extract itself in improving skin health.
9
Significant improvement
1 people found this helpful
I have noticed fewer acne since starting this! It has a mild scent and is easy to swallow. After a week, my skin became less oily, and my acne significantly improved. It's likely due to this version being non-decaffeinated, allowing me to enjoy it in the morning.
7.5
Less acne for son
After giving this to my son, I observed that his facial acne has significantly decreased, and there are fewer breakouts!
6
Less prone to breakouts
I began taking green tea extract to enhance my skin. I learned that the EGCG in green tea possesses antioxidant and anti-inflammatory traits, beneficial for battling ageing and acne. While I enjoy drinking green tea, I sought higher levels of EGCG to see visible results. So far, my skin appears less prone to breakouts, and I plan to keep taking these capsules.
7.5
Less acne noticed
2 people found this helpful
Everyone knows how beneficial green tea is, but not all enjoy it brewed. Capsules are a fantastic alternative as they provide a higher concentration of green tea. I’ve been using this supplement for quite some time, and whilst I don't have specific skin issues, I do believe in its efficacy. It lifts my mood, invigorates me, and after using it, my skin appears cleaner with fewer acne. This is likely due to its detoxifying properties. I hope my review proves useful!
6
Skin has improved
2 people found this helpful
I read a study showing that green tea extract can reduce acne, so I opted for these pills. Although I'm also taking other supplements, I believe my skin has improved. They're easy to swallow and have no unpleasant odour or taste. Next time, I think I’ll choose a caffeine-free green tea extract.
7.5
Fewer acne noted
63 people found this helpful
Everyone knows how useful green tea is. While many prefer it brewed, in capsule form the concentration is far greater. Since starting this supplement, my mood has improved remarkably, and I feel more energetic. After the course, my skin looks clearer, and there are noticeably fewer acne. The capsules help detoxify and cleanse the liver too. If my review has helped, I would appreciate a click on YES. It’s a small effort for you but means a lot to me! Thank you!
8
Topical GTE effectively reduces acne
The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials.
We examined the impact of green tea extract (GTE) on acne through a comprehensive review and analysis of five randomized clinical trials. Our findings showed that topical GTE significantly decreased the number of inflammatory lesions, suggesting that applying it directly to the skin is effective.
However, oral GTE had minimal effects on acne reduction. While non-inflammatory lesions did decrease with topical GTE, the benefits of taking GTE by mouth were negligible. Overall, this research highlights that topical GTE is a promising treatment for acne with few side effects.
9
Green tea lotion effectively treats acne
The efficacy of topical 2% green tea lotion in mild-to-moderate acne vulgaris.
We aimed to find out how effective a 2% green tea lotion is for treating mild-to-moderate acne. In a study involving 20 participants, the lotion was applied twice daily for six weeks.
Results showed a significant reduction in acne lesions, with total lesion counts dropping an impressive 58.33%, confirming its effectiveness. The severity of acne also notably improved.
Overall, we found that green tea lotion is a promising, cost-effective option for acne management.
8
Green tea extract reduces skin sebum
Outcomes of 3% green tea emulsion on skin sebum production in male volunteers.
We explored the impact of a 3% green tea emulsion on skin oiliness among healthy volunteers over eight weeks. Utilizing a specialized formulation, we measured sebum production using a Sebumeter, and our findings demonstrated a statistically significant decrease in skin sebum.
This suggests that green tea extract could be a promising option for addressing acne-related issues. The results encourage further research on its effectiveness in individuals with acne, providing hope for better skin management.
7
GTE shows mixed results for acne
Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial.
We conducted a well-structured clinical trial to explore whether decaffeinated green tea extract (GTE) improves acne in women aged 25 to 45 experiencing moderate to severe outbreaks. Over four weeks, participants received either GTE or a placebo.
The results showed that those taking GTE experienced significant reductions in inflammatory lesions on areas like the nose and chin. However, overall lesion counts didn’t differ markedly from the placebo group. While GTE appeared promising for specific lesions, further studies are needed to fully understand its effectiveness for acne treatment.
9
Sodium ascorbyl phosphate for acne
Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris.
We explored the potential of sodium ascorbyl phosphate (SAP), a stable form of vitamin C, in preventing and treating acne vulgaris. The study included a time-kill analysis showing that a 1% SAP formulation reduced the harmful bacteria Propionibacterium acnes by a significant log reduction of 5 after 8 hours. This demonstrates the strong antimicrobial properties of SAP against acne-causing bacteria.
Additionally, we observed an in vivo study with 20 participants, where the SAP formulation effectively prevented up to 40% of UVA-induced sebum oxidation, suggesting it can help reduce inflammation associated with acne. In another open-label study involving 60 volunteers over 12 weeks, a 5% SAP lotion was rated as excellent or good in effectiveness by 76.9% of the participants, outperforming a commonly prescribed acne treatment.
Overall, our findings indicate that sodium ascorbyl phosphate could serve as an effective, non-antibiotic option for both the prevention and treatment of acne, making it an attractive addition to cosmetic products due to its lack of side effects.
9
Vitamin C shows effectiveness for acne
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
We explored the effectiveness of vitamin C in treating acne, focusing on its antioxidant and anti-inflammatory properties. Vitamin C, also known as L-ascorbic acid, is a natural component of our skin and plays a vital role in protecting it from oxidative stress.
Our findings highlight that vitamin C can be beneficial for acne control, although to truly maximize its effects, proper formulations are essential. The study indicates that when used in combination with other vitamins such as E and B3, vitamin C may have enhanced efficacy.
However, it's important to note that while vitamin C shows promise, it should be viewed as part of a broader skincare routine rather than a standalone solution for acne treatment.
References
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Shields A, Ly S, Wafae B, Chang YF, Manjaly P, et al. Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review. JAMA Dermatol. 2023;159:1373. 10.1001/jamadermatol.2023.3949
Kim S, Park TH, Kim WI, Park S, Kim JH, et al. The effects of green tea on acne vulgaris: A systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2021;35:374. 10.1002/ptr.6809
Lu PH, Hsu CH. Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial. Complement Ther Med. 2016;25:159. 10.1016/j.ctim.2016.03.004
Jung MK, Ha S, Son JA, Song JH, Houh Y, et al. Polyphenon-60 displays a therapeutic effect on acne by suppression of TLR2 and IL-8 expression via down-regulating the ERK1/2 pathway. Arch Dermatol Res. 2012;304:655. 10.1007/s00403-012-1249-x
Mahmood T, Akhtar N, Khan BA, Khan HM, Saeed T. Outcomes of 3% green tea emulsion on skin sebum production in male volunteers. Bosn J Basic Med Sci. 2010;10:260.
Elsaie ML, Abdelhamid MF, Elsaaiee LT, Emam HM. The efficacy of topical 2% green tea lotion in mild-to-moderate acne vulgaris. J Drugs Dermatol. 2009;8:358.
Sharquie KE, Al-Turfi IA, Al-Shimary WM. Treatment of acne vulgaris with 2% topical tea lotion. Saudi Med J. 2006;27:83.
Sharara MA, Fawaz GA, El Samahy MH. Efficacy of tranexamic acid solution versus vitamin C solution after micro-needling in treatment of persistent post acne erythema: a split face clinical and 3DAntera camera comparative study. Arch Dermatol Res. 2024;317:150. 10.1007/s00403-024-03582-0
Golonka I, Łukasiewicz IW, Sebastiańczyk A, Greber KE, Sawicki W, et al. The Influence of the Amphiphilic Properties of Peptides on the Phosphatidylinositol Monolayer in the Presence of Ascorbic Acid. Int J Mol Sci. 2024;25. 10.3390/ijms252312484
Hu JK, Quinonez RL, Antasiuk V, Waibel J. Treatment of Acne Vulgaris-Associated Post-Inflammatory Dyschromia With Combination of Non-Ablative Laser Therapy and Topical Antioxidants. J Drugs Dermatol. 2024;23:769. 10.36849/JDD.8309
Abbas MAM, Elgamal EEAE, Zaky MS, Elsaie ML. Microneedling with topical vitamin C versus microneedling with topical insulin in the treatment of atrophic post-acne scars: A split-face study. Dermatol Ther. 2022;35:e15376. 10.1111/dth.15376
Sawutdeechaikul P, Kanokrungsee S, Sahaspot T, Thadvibun K, Banlunara W, et al. Detachable dissolvable microneedles: intra-epidermal and intradermal diffusion, effect on skin surface, and application in hyperpigmentation treatment. Sci Rep. 2021;11:24114. 10.1038/s41598-021-03503-5
Amer SS, Nasr M, Abdel-Aziz RTA, Moftah NH, El Shaer A, et al. Cosm-nutraceutical nanovesicles for acne treatment: Physicochemical characterization and exploratory clinical experimentation. Int J Pharm. 2020;577:119092. 10.1016/j.ijpharm.2020.119092
Vasanth S, Dubey A, G S R, Lewis SA, Ghate VM, et al. Development and Investigation of Vitamin C-Enriched Adapalene-Loaded Transfersome Gel: a Collegial Approach for the Treatment of Acne Vulgaris. AAPS PharmSciTech. 2020;21:61. 10.1208/s12249-019-1518-5
Khan H, Akhtar N, Ali A. Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers. Drug Res (Stuttg). 2017;67:52. 10.1055/s-0042-118171
Jain A, Garg NK, Jain A, Kesharwani P, Jain AK, et al. A synergistic approach of adapalene-loaded nanostructured lipid carriers, and vitamin C co-administration for treating acne. Drug Dev Ind Pharm. 2016;42:897. 10.3109/03639045.2015.1104343
Lee WJ, Kim SL, Choe YS, Jang YH, Lee SJ, et al. Magnesium Ascorbyl Phosphate Regulates the Expression of Inflammatory Biomarkers in Cultured Sebocytes. Ann Dermatol. 2015;27:376. 10.5021/ad.2015.27.4.376
Ikeno H, Apel M, Zouboulis C, Luger TA, Böhm M. L-Ascorbyl-2-phosphate attenuates NF-κB signaling in SZ95 sebocytes without affecting IL-6 and IL-8 secretion. Arch Dermatol Res. 2015;307:595. 10.1007/s00403-015-1565-z
Chawla S. Split Face Comparative Study of Microneedling with PRP Versus Microneedling with Vitamin C in Treating Atrophic Post Acne Scars. J Cutan Aesthet Surg. 2014;7:209. 10.4103/0974-2077.150742
Iinuma K, Noguchi N, Nakaminami H, Sasatsu M, Nishijima S, et al. Susceptibility of Propionibacterium acnes isolated from patients with acne vulgaris to zinc ascorbate and antibiotics. Clin Cosmet Investig Dermatol. 2011;4:161. 10.2147/CCID.S23840
Woolery-Lloyd H, Baumann L, Ikeno H. Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial. J Cosmet Dermatol. 2010;9:22. 10.1111/j.1473-2165.2010.00480.x
Burgess C. Topical vitamins. J Drugs Dermatol. 2008;7:s2.
Klock J, Ikeno H, Ohmori K, Nishikawa T, Vollhardt J, et al. Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris. Int J Cosmet Sci. 2005;27:171. 10.1111/j.1467-2494.2005.00263.x