Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.8
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Sodium (from Sodium Hyaluronate)
10 mg
< 1 %
Hyaluronic Acid (from Sodium Hyaluronate)
100 mg
†
L-Proline (Free-Form)
100 mg
†
Alpha Lipoic Acid
50 mg
†
Grape Seed Extract (Vitis vinifera)(Standardized for Polyphenols)
25 mg
†
Top Medical Research Studies
8
We looked into how a new treatment combining hyaluronic acid with a peptide from fibroblast growth factor 2 could help combat acne. This method targets specific receptors involved in acne development, showing promise by reducing both acne lesions and excess oil production in lab tests. Importantly, our study revealed that this treatment does not encourage certain reactions that would typically hinder acne management. While the results are positive, we acknowledge that ongoing research is necessary for further confirmation of these findings.
Read More
9
We explored the effectiveness of a high-concentration (4.5%) hyaluronic acid filler designed to treat facial acne scars. Participants received two treatments, and we evaluated improvements after four months.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
Read More
8
We evaluated how two types of hyaluronic acid fillers can impact acne scarring. In a well-structured study, thirty patients received injections of a new formulation with high and low molecular weight HA on one side of their face and a traditional HA filler on the other.
While the traditional filler showed quicker results, the new combined HA formulation provided more pronounced improvements over time. This suggests that hyaluronic acid treatments may offer varying benefits depending on the formulation used.
While the traditional filler showed quicker results, the new combined HA formulation provided more pronounced improvements over time. This suggests that hyaluronic acid treatments may offer varying benefits depending on the formulation used.
Read More
Most Useful Reviews
10
Acne gone forever
23 people found this helpful
I have experienced a remarkable improvement in my skin condition, and I can happily say that my acne has vanished after years of struggle. At 33, not only has my skin improved, but the hyaluron has also helped alleviate pain in my knee, which feels much better now.
Read More
0
Unpleasant reaction experienced
1 people found this helpful
Initially excited to try the miracle pill, I discovered after three days that my back was breaking out in large, unpleasant acne. Eventually, I realised that hyaluronic acid was causing this reaction. Once I stopped taking it, the acne ceased, but the marks will take time to heal. I won’t be ordering again.
Read More
9
Skin condition improved
I drink fish collagen (marine or from California), silicon and vitamin C on an empty stomach every morning, along with hyaluron. After a month, I'm pleased to note that my skin condition has improved significantly. I also face inflamed skin before ovulation and at the start of my cycle, so I've added DHT blockers such as saw palmetto to my routine.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.8
- All Researches
9
We explored the effectiveness of a high-concentration (4.5%) hyaluronic acid filler designed to treat facial acne scars. Participants received two treatments, and we evaluated improvements after four months.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
Read More
9
Promising treatment for acne scars
We examined how needle-free electronic pneumatic injections of hyaluronic acid could treat facial acne scars. In a carefully designed study, thirty Japanese participants received treatments on one side of their face, with follow-ups conducted for three months after completing three sessions.
Remarkably, 48.3% of the treated sides showed significant improvement, while none of the untreated sides did. Participants reported high satisfaction rates and the results were confirmed by imaging analysis. Overall, this treatment demonstrated promising effects on rolling acne scars with minimal side effects.
Remarkably, 48.3% of the treated sides showed significant improvement, while none of the untreated sides did. Participants reported high satisfaction rates and the results were confirmed by imaging analysis. Overall, this treatment demonstrated promising effects on rolling acne scars with minimal side effects.
Read More
9
Hyaluronic acid shows scar improvement
This study explored the effectiveness of using hyaluronic acid filler alongside subcision for treating post-acne scars.
In a controlled trial with 40 participants, we observed that both the subcision combined with hyaluronic acid and with fractional CO laser treatments showed significant improvements.
However, when comparing the two enhanced methods, neither was found to be statistically better than the other. Importantly, subcision alone still provided some improvement, even if modest. Overall, combining these treatments appears beneficial without serious side effects.
In a controlled trial with 40 participants, we observed that both the subcision combined with hyaluronic acid and with fractional CO laser treatments showed significant improvements.
However, when comparing the two enhanced methods, neither was found to be statistically better than the other. Importantly, subcision alone still provided some improvement, even if modest. Overall, combining these treatments appears beneficial without serious side effects.
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9
We evaluated the impact of combining subcision with hyaluronic acid (HA) on atrophic acne scars. Forty patients received subcision treatments over three sessions, followed by either HA or threads on one side of the face, while the other side served as a control.
The results showed that after 6 months, 94.1% of patients in the HA group experienced significant improvement compared to 67.3% with subcision alone. Patient satisfaction was notably higher for those who received the combined treatment. Side effects were mild and temporary, making this combination a promising option for better scar management.
The results showed that after 6 months, 94.1% of patients in the HA group experienced significant improvement compared to 67.3% with subcision alone. Patient satisfaction was notably higher for those who received the combined treatment. Side effects were mild and temporary, making this combination a promising option for better scar management.
Read More
8
We evaluated how two types of hyaluronic acid fillers can impact acne scarring. In a well-structured study, thirty patients received injections of a new formulation with high and low molecular weight HA on one side of their face and a traditional HA filler on the other.
While the traditional filler showed quicker results, the new combined HA formulation provided more pronounced improvements over time. This suggests that hyaluronic acid treatments may offer varying benefits depending on the formulation used.
While the traditional filler showed quicker results, the new combined HA formulation provided more pronounced improvements over time. This suggests that hyaluronic acid treatments may offer varying benefits depending on the formulation used.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
Acne gone forever
23 people found this helpful
I have experienced a remarkable improvement in my skin condition, and I can happily say that my acne has vanished after years of struggle. At 33, not only has my skin improved, but the hyaluron has also helped alleviate pain in my knee, which feels much better now.
Read More
0
Unpleasant reaction experienced
1 people found this helpful
Initially excited to try the miracle pill, I discovered after three days that my back was breaking out in large, unpleasant acne. Eventually, I realised that hyaluronic acid was causing this reaction. Once I stopped taking it, the acne ceased, but the marks will take time to heal. I won’t be ordering again.
Read More
9
Skin condition improved
I drink fish collagen (marine or from California), silicon and vitamin C on an empty stomach every morning, along with hyaluron. After a month, I'm pleased to note that my skin condition has improved significantly. I also face inflamed skin before ovulation and at the start of my cycle, so I've added DHT blockers such as saw palmetto to my routine.
Read More
9
Effective for acne
I take hyaluronic acid to tackle my bad acne, and it works quite well for me.
Read More
6
Soft and smooth skin
2 people found this helpful
After using transparent phytic acid for a month, I now find my skin soft and smooth, with a marked decrease in acne development. My skin no longer feels dry, and I also no longer experience tightness in my knees.
Read More
Frequently Asked Questions
9
Skin condition improved
I drink fish collagen (marine or from California), silicon and vitamin C on an empty stomach every morning, along with hyaluron. After a month, I'm pleased to note that my skin condition has improved significantly. I also face inflamed skin before ovulation and at the start of my cycle, so I've added DHT blockers such as saw palmetto to my routine.
7.5
Reduced acne noted
I have noticed improved skin hydration and a reduction in acne. There’s no taste, and I haven't observed any changes in my wrinkles.
0
Unpleasant reaction experienced
1 people found this helpful
Initially excited to try the miracle pill, I discovered after three days that my back was breaking out in large, unpleasant acne. Eventually, I realised that hyaluronic acid was causing this reaction. Once I stopped taking it, the acne ceased, but the marks will take time to heal. I won’t be ordering again.
10
Acne gone forever
23 people found this helpful
I have experienced a remarkable improvement in my skin condition, and I can happily say that my acne has vanished after years of struggle. At 33, not only has my skin improved, but the hyaluron has also helped alleviate pain in my knee, which feels much better now.
4
Occasional acne occurrence
I took one capsule each morning, and my face feels tight and plump. However, I do occasionally get acne on my chin. I've found that once I stop taking the capsules, my acne clears up, so I'll seek other brands.
7
Hyaluronic acid gel shows promise
We investigated a unique hyaluronic acid gel, combined with hydrogen peroxide and glycine, to treat mild to moderate acne. Over 8 weeks, 40 participants applied the gel multiple times a day and were frequently evaluated.
Although the results indicated some clinical benefits in reducing acne lesions and improving skin quality, they suggest this treatment might be best used alongside retinoids. Importantly, the product showed a good safety profile, although it may not be a standalone solution for everyone.
Although the results indicated some clinical benefits in reducing acne lesions and improving skin quality, they suggest this treatment might be best used alongside retinoids. Importantly, the product showed a good safety profile, although it may not be a standalone solution for everyone.
9
We explored the effectiveness of a high-concentration (4.5%) hyaluronic acid filler designed to treat facial acne scars. Participants received two treatments, and we evaluated improvements after four months.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
Notably, patients experienced a 12% improvement in scar severity shortly after treatment and a significant 31% improvement after four months. The skin's depth measurement also showed a 20% reduction in acne scar deepness with no serious side effects reported.
These promising results suggest that this hyaluronic acid formulation could be a valuable option for individuals seeking to improve their acne scarring.
7
We aimed to evaluate the effectiveness of microneedling alone compared to microneedling combined with hyaluronic acid in treating acne scars.
After conducting treatment on 60 patients, we observed that while most experienced moderate improvement, those receiving the combination treatment reported better outcomes, including “good” and “very good” results.
This procedure is straightforward and can be performed in various settings, with hyaluronic acid significantly boosting the results of microneedling alone.
After conducting treatment on 60 patients, we observed that while most experienced moderate improvement, those receiving the combination treatment reported better outcomes, including “good” and “very good” results.
This procedure is straightforward and can be performed in various settings, with hyaluronic acid significantly boosting the results of microneedling alone.
7
We examined how well hyaluronic acid (HA)—both non-crosslinked and crosslinked—works for treating aesthetic skin issues, including acne scars. In our analysis of 115 patient records, both HA types produced notable improvements in skin appearance with minimal side effects. Patients reported high satisfaction levels and experienced improvements that averaged around 1.7 on the Global Aesthetic Improvement Scale. Interestingly, both forms of HA had a similar longevity in results, lasting around 13 months. This study highlights the promise of HA in tackling acne-related concerns, offering effective and safe treatment options.
References
- Stefancu ME, Barattini DF, Botnaru I, Vizman C, Stucchi L, et al. Performance and Safety of the Medical Device Ialuxid Gel in the Treatment of Mild-Moderate Acne Vulgaris: An Open-Label, Noncomparative Multicentre Interventional Clinical Trial. J Cosmet Dermatol. 2025;24:e70084. doi:10.1111/jocd.70084
- Sparavigna A, Grimolizzi F, Cigni C, Lualdi R, Bellia G. Dual-Plane Treatment With Highly Concentrated Hybrid Cooperative Complexes of Hyaluronans for Facial Atrophic Acne Scars. Dermatol Surg. 2025;51:152. doi:10.1097/DSS.0000000000004387
- Mohamed SH, Omar GA, Hamdy AE. Microneedling with Topical Insulin Versus Microneedling with Non-Cross-Linked Hyaluronic Acid for Atrophic Post-Acne Scars: A Split-Face Study. Dermatol Pract Concept. 2024;14. doi:10.5826/dpc.1403a183
- Dastgheib M, Heidari S, Azizipour A, Kavyani M, Lajevardi V, et al. Investigating the impact of added Profhilo mesogel to subcision versus subcision monotherapy in treating acne scars; a single-blinded, split-face randomized trial. J Cosmet Dermatol. 2024;23:1992. doi:10.1111/jocd.16258
- Bano R, Brar BK, Kumar S. Comparative Evaluation of Therapeutic Efficacy and Safety of Microneedling Alone Versus Microneedling with Hyaluronic Acid in Post-Acne Scarring. J Cutan Aesthet Surg. 2023;16:279. doi:10.4103/JCAS.JCAS_6_23
- Behrangi E, Dehghani A, Sheikhzadeh F, Goodarzi A, Roohaninasab M. Evaluation and comparison of the efficacy and safety of cross-linked and non-cross-linked hyaluronic acid in combination with botulinum toxin type A in the treatment of atrophic acne scars: A double-blind randomized clinical trial. Skin Res Technol. 2024;30:e13541. doi:10.1111/srt.13541
- Kaminaka C, Sakata M, Nishiguchi M, Kunimoto K, Mikita N, et al. Clinical evaluation of needle-free electronic pneumatic hyaluronic acid injection treatment for facial atrophic acne scars: A prospective, randomized comparative trial. J Dermatol. 2023;50:971. doi:10.1111/1346-8138.16830
- Mehrabi J, Shehadeh W, Gallo ES, Artzi O, Horovitz T. Comparison of 2 Hyaluronic Acid-based Fillers for the Treatment of Acne Scars: Structural Lifting Versus Biostimulatory Effect. Dermatol Surg. 2023;49:581. doi:10.1097/DSS.0000000000003789
- Su Z, Zhang Y, Cao J, Sun Y, Cai Y, et al. Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist. J Nanobiotechnology. 2023;21:55. doi:10.1186/s12951-023-01812-7
- Abdelwahab AA, Omar GAB, Hamdino M. A combined subcision approach with either fractional CO laser (10,600 nm) or cross-linked hyaluronic acid versus subcision alone in atrophic post-acne scar treatment. Lasers Med Sci. 2022;38:20. doi:10.1007/s10103-022-03677-y
- Mohammed GF, Al-Dhubaibi MS. Triple steps acne scar revision technique: A new combination therapeutic modality for atrophic acne scars. J Cosmet Dermatol. 2022;21:4659. doi:10.1111/jocd.14944
- Ebrahim HM, Nassar A, ElKashishy K, Artima AYM, Morsi HM. A combined approach of subcision with either cross-linked hyaluronic acid or threads in the treatment of atrophic acne scars. J Cosmet Dermatol. 2022;21:3334. doi:10.1111/jocd.14675
- MacGillis D, Vinshtok Y. High-velocity pneumatic injection of non-crosslinked hyaluronic acid for skin regeneration and scar remodeling: A retrospective analysis of 115 patients. J Cosmet Dermatol. 2021;20:1098. doi:10.1111/jocd.14002
