Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Carnosine (B-alanyl-L-histidine)
500 mg
*

Top Medical Research Studies

8
L-Carnosine's role in flu treatment
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.

The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.

Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.

Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
Read More
7
L-carnosine may aid flu response
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.

Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.

Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.

Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
Read More
7
l-carnosine aids flu response
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.

Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.

Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.

Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.
Read More

Most Useful Reviews

10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
Read More
4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
Read More
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
  • All Researches
8
L-Carnosine's role in flu treatment
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.

The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.

Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.

Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
Read More
7
L-carnosine may aid flu response
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.

Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.

Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.

Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
Read More
7
l-carnosine aids flu response
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.

Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.

Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.

Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
Read More
4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
Read More
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
Read More

Frequently Asked Questions

4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
7
L-carnosine may aid flu response
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.

Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.

Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.

Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
8
L-Carnosine's role in flu treatment
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.

The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.

Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.

Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
7
l-carnosine aids flu response
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.

Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.

Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.

Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.

References

  1. Babizhayev MA, Deyev AI, Yegorov YE. L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, prevention and self-care as an alternative to the conventional vaccination?. Curr Clin Pharmacol. 2014;9:93.
  2. Babizhayev MA, Deyev AI, Yegorov YE. Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide ("bioactivated Jewish penicillin") as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macrophages in the human body infected with the virulent swine influenza A (H1N1) virus. J Basic Clin Physiol Pharmacol. 2013;24:1. doi:10.1515/jbcpp-2012-0037
  3. Babizhayev MA, Deyev AI. Management of the virulent influenza virus infection by oral formulation of nonhydrolized carnosine and isopeptide of carnosine attenuating proinflammatory cytokine-induced nitric oxide production. Am J Ther. 2012;19:e25. doi:10.1097/MJT.0b013e3181dcf589
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