Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide ("bioactivated Jewish penicillin") as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macrophages in the human body infected with the virulent swine influenza A (H1N1) virus.
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.
The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.
Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.
Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
Read More
7
L-carnosine may aid flu response
L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, prevention and self-care as an alternative to the conventional vaccination?
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.
Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.
Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.
Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
Read More
7
l-carnosine aids flu response
Management of the virulent influenza virus infection by oral formulation of nonhydrolized carnosine and isopeptide of carnosine attenuating proinflammatory cytokine-induced nitric oxide production.
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.
Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.
Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.
Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.
Read More
Most Useful Reviews
10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
Read More
4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
Read More
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide ("bioactivated Jewish penicillin") as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macrophages in the human body infected with the virulent swine influenza A (H1N1) virus.
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.
The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.
Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.
Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
Read More
7
L-carnosine may aid flu response
L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, prevention and self-care as an alternative to the conventional vaccination?
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.
Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.
Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.
Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
Read More
7
l-carnosine aids flu response
Management of the virulent influenza virus infection by oral formulation of nonhydrolized carnosine and isopeptide of carnosine attenuating proinflammatory cytokine-induced nitric oxide production.
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.
Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.
Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.
Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
Read More
4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
Read More
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
Read More
Frequently Asked Questions
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
L-Carnosine is a naturally occurring dipeptide composed of two amino acids, beta-alanine and L-histidine. It is primarily found in high concentrations in muscle and brain tissues, where it plays a role in various biological functions. L-Carnosine is known for its potential antioxidant properties, helping to protect cells from oxidative stress and damage caused by free radicals. Additionally, it is believed to have a buffering effect on pH levels in muscles, which may enhance athletic performance and delay fatigue during intense exercise.
Research surrounding L-Carnosine has suggested it may contribute to healthy aging by promoting cellular function and reducing age-related decline. Some studies indicate that it could support cognitive function and may even have potential benefits for conditions such as Alzheimer’s disease. However, it's important to note that while L-Carnosine can be obtained through dietary sources, supplementation and its effects should be approached with caution, as more research is necessary to fully understand its benefits and any potential interactions with other medications. If you're considering adding L-Carnosine to your health regimen, consulting with a healthcare professional is advisable.
Based on user reviews, the timeline for seeing results from this supplement during flu season can vary significantly. One user mentioned taking the supplement daily for 10 days without noticing immediate results in terms of flu symptoms, but they found that it improved their overall energy levels and could aid in preventing colds and flu Read Review. In contrast, another reviewer reported a significant improvement in their immunity after taking the supplement, indicating that within a shorter timeframe, results can be quite positive Read Review.
It appears that while some users may see results relatively quickly, within days, others might require a longer duration of use to experience the full benefits of the supplement. Factors such as individual health conditions and adherence to the dosage can affect the efficacy. Therefore, it would be reasonable to expect variable outcomes, with some users experiencing positive changes within a week while others may take longer to notice any significant effects.
L-carnosine, a naturally occurring dipeptide, has shown potential benefits against influenza based on several scientific studies. Research indicates that L-carnosine can stimulate neutrophils, a type of white blood cell crucial in fighting infections, thereby enhancing the immune response against the influenza virus [1]. Additionally, it has been observed that L-carnosine can reduce harmful nitric oxide production and inhibit virus replication in infected cells, suggesting a protective role during flu infections [2].
Further investigations into various formulations of L-carnosine have suggested that its non-hydrolyzed forms, particularly those derived from natural sources like chicken extracts, retain their effectiveness in both the digestive tract and bloodstream [2]. This makes them suitable for oral supplementation as part of an overall preventive approach to flu. Given its ability to modulate the immune response and mitigate severe reactions that can arise from influenza infections, L-carnosine emerges as a promising complementary option in flu treatment strategies, as supported by ongoing research [3].
Users have reported various improvements in their symptoms after using this supplement, particularly regarding immunity and overall health. One reviewer highlighted that since starting the supplement, their immunity has strengthened, and they no longer experience flu symptoms, underscoring its effectiveness as recommended by their doctor Read Review. Another user noted that while they didn’t see immediate results within the first ten days, they did find that taking the supplement after workouts helped significantly reduce the likelihood of colds and flu during the cold season, indicating a protective benefit Read Review.
Moreover, one user with a sensitive stomach reported that the supplement resolved their reflux esophagitis, although they noted it didn't alleviate menstrual stomach pain. This demonstrates that while many have experienced positive results related to immunity and digestive discomfort, the effects may vary based on individual health conditions and needs Read Review. Overall, while some users report quick health benefits, others may require consistent use over a longer period to notice significant improvements, emphasizing the need for individualized expectations.
Based on user reviews, there seems to be a generally positive sentiment regarding the combination of this supplement with other supplements to handle flu symptoms. One reviewer noted that taking the supplement after workouts significantly reduced the likelihood of colds, flu, and other respiratory illnesses, emphasizing its protective benefits during the cold season Read Review. This suggests that users find it effective when incorporated into a broader regimen aimed at bolstering immunity and overall health during flu season.
Additionally, another user reported a strong improvement in their immunity and stated they no longer experience flu symptoms after following their doctor's recommendation to use this supplement, indicating that it may work well in conjunction with other health practices Read Review. While some users have not yet noticed immediate effects, many believe that consistent use, especially alongside supportive health measures, can enhance the overall effectiveness of the supplement.
Based on user reviews, there's no consensus on a specific dose of L Carnosine for treating the flu. One user mentioned that taking the supplement for 10 days during cold and flu season did not yield noticeable results, despite appreciating other benefits such as boosted energy and reduced swelling after workouts Read Review. Another reviewer credited the vitamin for strengthening their immunity and noted a lack of flu symptoms, possibly implying that they found it effective, though no specific dosage was detailed Read Review.
Overall, users have reported mixed experiences with L Carnosine in relation to flu treatment, with some finding it beneficial for general health during the cold season while others did not see immediate effects. This suggests that individual responses may vary significantly, and specific dosing recommendations for flu treatment remain unclear based on the shared reviews.
4
Reduces flu risk
3 people found this helpful
Great for cold and flu season, I took it for 10 days in the morning, but haven't noticed any results yet. There is no unpleasant taste, especially with coffee—it gives a boost of energy. It didn’t significantly affect my workouts or muscles, just a bit more endurance. After reading reviews about its effect on skin, I’ve seen no results so far. I'll finish the jar and update my review. After finishing the package: I appreciated the benefits and the composition. The ingredients are reliable, and the capsule size is just right. Taking it at night means I wake up without swelling. In the cold season, it's excellent to have after workouts, as it greatly reduces the likelihood of colds, flu, and other respiratory illnesses. I’ll order more once this runs out.
10
Improves immunity
This vitamin is excellent; my immunity is strong, and I no longer have the flu. My doctor recommended this brand, and I am very pleased with it.
6
Stomach pain relief
1 people found this helpful
My stomach is sensitive when I'm hungry, and I’ve dealt with reflux esophagitis, but this resolved that issue. However, it didn’t help with my menstrual stomach pain. I will continue to use it.
7
L-carnosine may aid flu response
L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, prevention and self-care as an alternative to the conventional vaccination?
We explored how L-carnosine, a naturally occurring dipeptide, might influence the immune response to the influenza virus, particularly focusing on neutrophils, a type of white blood cell important in fighting infections.
Our findings indicated that L-carnosine can stimulate a respiratory burst in neutrophils, a process crucial for destroying influenza viruses. This suggests that boosting the activity of neutrophils with L-carnosine could provide a beneficial effect against flu infections by enhancing the body's natural defenses.
Moreover, we observed that L-carnosine and its related compound, anserine, not only enhance the immune response but also reduce apoptosis, or cell death, in neutrophils. This means they help immune cells to persist longer and better fight off viral infections.
Overall, the research points to L-carnosine as a promising complementary approach for influenza treatment and prevention, especially as a non-vaccine option that might be used alongside conventional treatments. While this study doesn’t rule out the effectiveness of traditional vaccines, it highlights an intriguing avenue for boosting our defenses against flu viruses.
8
L-Carnosine's role in flu treatment
Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide ("bioactivated Jewish penicillin") as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macrophages in the human body infected with the virulent swine influenza A (H1N1) virus.
We observed that L-carnosine, a natural peptide, shows promise in addressing influenza A virus infections, particularly the problematic H1N1 strain. This study highlights how L-carnosine can potentially influence the immune response during flu infections, which is crucial given the virus's ability to evade our defenses.
The effects of L-carnosine include the reduction of harmful nitric oxide production and the inhibition of virus replication in infected cells. Essentially, L-carnosine may act as a protective agent against the cellular damage typically caused by the flu virus. By helping to modulate the immune response, it might also aid in reducing symptoms and complications associated with flu infections.
Additionally, the study emphasizes the significance of L-carnosine's non-hydrolyzed forms, which maintain their effectiveness in the digestive tract and bloodstream, making them particularly beneficial for oral supplementation. Products derived from chicken extracts, noted for their high L-carnosine content, could be part of a preventive approach to flu.
Overall, L-carnosine appears to be a strong candidate in flu treatment strategies, especially given its ability to mitigate severe immune responses that can lead to complications in vulnerable populations.
7
l-carnosine aids flu response
Management of the virulent influenza virus infection by oral formulation of nonhydrolized carnosine and isopeptide of carnosine attenuating proinflammatory cytokine-induced nitric oxide production.
We explored the effects of l-carnosine on influenza A virus infections. Through our research involving serum samples from 150 patients with the flu and 140 healthy individuals, we observed that patients with the virus showed significantly increased levels of nitric oxide, a marker often related to inflammation. This finding underscores the important role of inducible nitric oxide synthase (iNOS) in inflammation during flu infections.
Our studies also highlighted that when human lung cells were infected with the flu virus, there was an increase in pro-inflammatory agents like interleukin-32 and iNOS. These agents contribute to the release of nitric oxide, further amplifying inflammation. We noted how macrophages, immune cells that typically respond to infection, also produce nitric oxide when stimulated by pro-inflammatory cytokines.
Importantly, we identified how l-carnosine, especially its nonhydrolized oral forms, can play a protective role against the harmful effects of oxidants like peroxynitrite generated during flu infections. Carnosine might help manage the body's immune response, reduce the toxicity from nitric oxide, and possibly inhibit the replication of the virus.
Our findings suggest that natural sources rich in carnosine, such as chicken soup, could be beneficial for flu prevention, although they may face challenges due to enzymatic breakdown in the body. However, the specially developed formulas of nonhydrolized carnosine could offer promising avenues for controlling and preventing influenza A infections, making them a noteworthy area of exploration in viral infection management.
References
Babizhayev MA, Deyev AI, Yegorov YE. L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, prevention and self-care as an alternative to the conventional vaccination?. Curr Clin Pharmacol. 2014;9:93.
Babizhayev MA, Deyev AI, Yegorov YE. Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide ("bioactivated Jewish penicillin") as a panacea of tomorrow for various flu ailments: signaling activity attenuating nitric oxide (NO) production, cytostasis, and NO-dependent inhibition of influenza virus replication in macrophages in the human body infected with the virulent swine influenza A (H1N1) virus. J Basic Clin Physiol Pharmacol. 2013;24:1. doi:10.1515/jbcpp-2012-0037
Babizhayev MA, Deyev AI. Management of the virulent influenza virus infection by oral formulation of nonhydrolized carnosine and isopeptide of carnosine attenuating proinflammatory cytokine-induced nitric oxide production. Am J Ther. 2012;19:e25. doi:10.1097/MJT.0b013e3181dcf589