Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 6 Reviews
8.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Lysine (from 637 mg L-Lysine Hydrochloride)
500 mg
**

Top Medical Research Studies

We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.

Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.

We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.

Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Read More
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.

In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.

The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
Read More

Most Useful Reviews

9
Smooth skin achieved
6 people found this helpful
Against Herpes, For Beautiful Skin! I recommend drinking it if you have cold sores or problem skin. You will see results in a month! I drink for a month, take a break, then have the next one. I'm very happy so far! My facial skin has become perfectly smooth, without redness and acne! I highly recommend it! Thank you if you like it! 🤗💛
Read More
9
Effective for acne
1 people found this helpful
Works brilliantly for acne! It must be taken on an empty stomach.
Read More
9
Acne significantly improved
Excellent! It helps with acne and restores hormonal levels. I struggled with acne for over a year and tried numerous remedies, but nothing worked. After reading advice on a forum about drinking lysine, I decided to give it a go, despite my low expectations. After 2 weeks, nearly all my acne vanished, leaving my skin much clearer. Additionally, my cycle returned to normal. Overall, I am very pleased and will order again.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.

Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.

We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.

Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Read More
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.

In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.

The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Smooth skin achieved
6 people found this helpful
Against Herpes, For Beautiful Skin! I recommend drinking it if you have cold sores or problem skin. You will see results in a month! I drink for a month, take a break, then have the next one. I'm very happy so far! My facial skin has become perfectly smooth, without redness and acne! I highly recommend it! Thank you if you like it! 🤗💛
Read More
9
Effective for acne
1 people found this helpful
Works brilliantly for acne! It must be taken on an empty stomach.
Read More
9
Acne significantly improved
Excellent! It helps with acne and restores hormonal levels. I struggled with acne for over a year and tried numerous remedies, but nothing worked. After reading advice on a forum about drinking lysine, I decided to give it a go, despite my low expectations. After 2 weeks, nearly all my acne vanished, leaving my skin much clearer. Additionally, my cycle returned to normal. Overall, I am very pleased and will order again.
Read More
7.5
Reduced acne occurrences
I take it with proline. The condition of my skin has stabilised, and acne is occurring less frequently.
Read More
6
Works for acne
I used this previously for my skin and acne; I think it works.
Read More

Frequently Asked Questions

9
Smooth skin achieved
6 people found this helpful
Against Herpes, For Beautiful Skin! I recommend drinking it if you have cold sores or problem skin. You will see results in a month! I drink for a month, take a break, then have the next one. I'm very happy so far! My facial skin has become perfectly smooth, without redness and acne! I highly recommend it! Thank you if you like it! 🤗💛
9
Acne significantly improved
Excellent! It helps with acne and restores hormonal levels. I struggled with acne for over a year and tried numerous remedies, but nothing worked. After reading advice on a forum about drinking lysine, I decided to give it a go, despite my low expectations. After 2 weeks, nearly all my acne vanished, leaving my skin much clearer. Additionally, my cycle returned to normal. Overall, I am very pleased and will order again.
2
Minimal impact observed
It is unclear yet. I was searching for something for my joints, which constantly hurt. Some reviews mention an increase in energy. I agree it has become somewhat easier to do household chores and my overall health has improved. However, the effect is barely noticeable. I may need a higher dose, as I take 1 tablet in the morning before meals for 30-40 minutes. Regarding the cleanliness of my face, I haven’t noticed much improvement; I don’t suffer from herpes, but the acne on my temples didn’t disappear during PMS. Perhaps I need to take it more frequently. I’ve been drinking it for 10 days and have had no side effects.
7.5
Reduced acne occurrences
I take it with proline. The condition of my skin has stabilised, and acne is occurring less frequently.
9
Effective for acne
1 people found this helpful
Works brilliantly for acne! It must be taken on an empty stomach.
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.

Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.

We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.

Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.

In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.

The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.

References

  1. Leignadier J, Drago M, Lesouhaitier O, Barreau M, Dashi A, et al. Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin. Pharmaceutics. 2023;15. doi:10.3390/pharmaceutics15082083
  2. Attia-Vigneau J, Barreau M, Le Toquin E, Feuilloley MGJ, Loing E, et al. Polylysine dendrigraft is able to differentially impact Cutibacterium acnes strains preventing acneic skin. Exp Dermatol. 2022;31:1056. doi:10.1111/exd.14554
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