We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.
In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.
Read More
9.5
Oral PTH-Lysine complex enhances bone health
Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex.
We explored an innovative way to deliver the osteoporosis treatment parathyroid hormone (PTH) through oral microencapsulated complexes combined with L-lysine.
This approach enhances patient compliance compared to daily injections. Testing revealed that the oral formulation improved bioavailability and produced significant increases in bone density and volume in ovariectomized rats.
The findings suggest that this new method could be a promising option to improve bone health without the hassle of injections.
Read More
9
Oral teriparatide shows promise
Enhanced oral absorption of teriparatide with therapeutic potential for management of osteoporosis.
Our study focused on creating a better way to deliver teriparatide, a treatment for osteoporosis, using l-lysine. We developed a solid oral formulation that significantly improved the absorption of the hormone compared to traditional injections. The results showed that this new method not only maintained similar effectiveness in stimulating bone growth but also led to improved bone density and thickness in lab mice with osteoporosis. Overall, we found that oral teriparatide could be a promising option for managing osteoporosis.
Read More
Most Useful Reviews
9
Prevents osteoporosis
Now Foods L-Lysine 500 mg is crucial for health. It aids immunity and helps prevent and treat yeast, fungal infections, and herpes due to its role in collagen synthesis. It's essential for calcium absorption, which is vital in preventing osteoporosis.
Read More
9
Strengthens blood vessels
Lysine is vital for numerous bodily functions, including cardiovascular and brain health, metabolism, and skin. It helps manage herpes and respiratory infections and significantly aids in calcium absorption, essential for osteoporosis prevention.
Read More
7.5
Joint health focus
132 people found this helpful
The drug enhances the elasticity of veins, increases venous tone, and improves calcium absorption, which helps in preventing osteoporosis, particularly in those over 50-60 years. It also promotes collagen synthesis.
We explored an innovative way to deliver the osteoporosis treatment parathyroid hormone (PTH) through oral microencapsulated complexes combined with L-lysine.
This approach enhances patient compliance compared to daily injections. Testing revealed that the oral formulation improved bioavailability and produced significant increases in bone density and volume in ovariectomized rats.
The findings suggest that this new method could be a promising option to improve bone health without the hassle of injections.
Read More
9
Oral teriparatide shows promise
Enhanced oral absorption of teriparatide with therapeutic potential for management of osteoporosis.
Our study focused on creating a better way to deliver teriparatide, a treatment for osteoporosis, using l-lysine. We developed a solid oral formulation that significantly improved the absorption of the hormone compared to traditional injections. The results showed that this new method not only maintained similar effectiveness in stimulating bone growth but also led to improved bone density and thickness in lab mice with osteoporosis. Overall, we found that oral teriparatide could be a promising option for managing osteoporosis.
Read More
8
NSD2 inhibition may reduce osteoporosis
NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells.
We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.
In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Prevents osteoporosis
Now Foods L-Lysine 500 mg is crucial for health. It aids immunity and helps prevent and treat yeast, fungal infections, and herpes due to its role in collagen synthesis. It's essential for calcium absorption, which is vital in preventing osteoporosis.
Read More
9
Strengthens blood vessels
Lysine is vital for numerous bodily functions, including cardiovascular and brain health, metabolism, and skin. It helps manage herpes and respiratory infections and significantly aids in calcium absorption, essential for osteoporosis prevention.
Read More
7.5
Joint health focus
132 people found this helpful
The drug enhances the elasticity of veins, increases venous tone, and improves calcium absorption, which helps in preventing osteoporosis, particularly in those over 50-60 years. It also promotes collagen synthesis.
Read More
7.5
Bone health support
91 people found this helpful
I take lysine before meals; it aids calcium absorption and is essential for preventing osteoporosis. I also give it to my cat battling a herpes virus, as it's effective for both us and our pets.
Read More
7.5
Immune system boost
7 people found this helpful
I love this product! Lysine is crucial for protein synthesis and enhances the absorption of calcium, crucial in preventing osteoporosis.
Osteoporosis is a medical condition characterized by weakened bones, making them fragile and more prone to fractures. This condition occurs when the body loses too much bone mass, doesn't make enough bone, or a combination of both. As bones lose density, they can break more easily, often as a result of minor falls or injury. Osteoporosis is often referred to as a "silent disease" because bone loss occurs without any symptoms until a fracture occurs, often in the hip, spine, or wrist.
Risk factors for developing osteoporosis include age, gender (it’s more common in women), family history, low body weight, and certain medical conditions and medications. Lifestyle choices such as smoking, excessive alcohol consumption, and a diet low in calcium and vitamin D can also contribute to bone loss. Regular weight-bearing exercise, ensuring adequate nutrition, and, in some cases, medications can help prevent or manage osteoporosis. If you believe you may be at risk, it is important to consult with a healthcare professional for appropriate screening and intervention options.
L-Lysine is an essential amino acid that plays a crucial role in many bodily functions. Unlike some amino acids that can be synthesized by the body, L-Lysine must be obtained through diet or supplementation. It is particularly important for protein synthesis, hormone production, and the absorption of calcium. Good dietary sources of L-Lysine include meat, fish, dairy products, eggs, and certain plant sources such as beans and legumes. Athletes and individuals looking to support muscle recovery and growth often consider L-Lysine supplements.
In addition to its role in enhancing muscle recovery, L-Lysine is also often touted for its potential benefits in supporting immune function and combating cold sores caused by the herpes simplex virus. Some studies suggest that L-Lysine may help reduce the frequency and severity of these outbreaks. However, it’s always advisable to consult with a healthcare professional before starting any new supplement to determine the appropriate dosage and ensure it aligns with your health needs.
Based on user reviews, the timeline for noticing results from taking L-Lysine, particularly for osteoporosis prevention, varies. Many users report positive impacts on calcium absorption, which is crucial for bone health, but specific timelines for seeing tangible results are not consistently mentioned. For instance, one reviewer emphasizes that L-Lysine contributes to significantly improving calcium absorption and aids in osteoporosis prevention but does not specify a timeframe for results Read Review.
Several users highlight the importance of consistency in supplementation for the best outcomes. While some individuals may notice benefits relatively quickly, often within weeks, others might experience more gradual improvements over months. For better clarity, potential users might consider combining their supplementation with regular check-ups to monitor bone health effectively.
The supplement appears to be supported by scientific research regarding osteoporosis, particularly through advancements in delivery methods for osteoporosis treatments like teriparatide and parathyroid hormone (PTH). For instance, a study focused on a new oral formulation of teriparatide using l-lysine showed improved absorption and efficacy in stimulating bone growth, leading to enhanced bone density and thickness in lab mice with osteoporosis [2]. Additionally, another study demonstrated an innovative oral treatment combining PTH and l-lysine that not only improved patient compliance compared to injections but also significantly increased bone density and volume in testing [3].
Moreover, research examining the role of NSD2 in bone health indicated that targeting this factor could be a promising therapeutic strategy for preventing bone loss in osteoporosis [1]. Collectively, these findings present a compelling case for the effectiveness of these supplements in managing osteoporosis, making them worth considering when looking for options to improve bone health.
Based on user reviews, a variety of improvements in symptoms related to osteoporosis prevention and overall health have been reported among those taking L-Lysine. Many users note significant benefits to calcium absorption, which is essential for maintaining bone strength and preventing osteoporosis. For example, one reviewer highlights its critical role in improving calcium absorption and emphasizes that it is vital for osteoporosis prevention Read Review. Another user mentions that the supplement aids in not only preventing osteoporosis but also in managing heart health and improving nutrient utilization within the body Read Review.
In addition to its bone health benefits, users report positive effects on muscle mass, skin health, and immune support. One user points out improvements in muscle growth and increased energy, attributing these effects to enhanced calcium absorption from L-Lysine Read Review. Others have shared experiences of the supplement aiding in the management of viral conditions, like herpes, thanks to its immune-supportive properties Read Review. While these reviews paint a promising picture, it’s essential to remember that individual results can vary, and anyone considering L-Lysine supplementation should consult a healthcare provider to determine the best approach for their unique health needs.
Users have reported a range of complementary benefits when combining L-Lysine with other supplements for osteoporosis management. Many individuals emphasize its critical role in enhancing calcium absorption, which is essential for preventing osteoporosis. As one reviewer puts it, L-Lysine not only assists in calcium absorption but also helps with muscle growth, thereby aiding in overall health and osteoporosis prevention Read Review. Another user highlights that it enhances nutrient absorption, promoting better utilization of other supplements, which could potentially lead to synergistic effects in managing osteoporosis Read Review.
While users mostly recommend its use in conjunction with calcium-rich foods or supplements, some also suggest pairing it with collagen supplements to maximize its benefits for bone strength and overall health. For instance, one review notes that L-Lysine supports collagen production and calcium absorption, reinforcing its potential when taken alongside other supplements targeting bone health Read Review. However, users do advise consulting a healthcare provider for personalized supplementation strategies to address osteoporosis effectively.
Based on user reviews, many reported that L-Lysine is crucial for calcium absorption, which is essential for preventing osteoporosis. Reviewers emphasized the amino acid's role in enhancing calcium uptake and promoting healthier bones. For instance, one user mentioned that taking L-Lysine before meals significantly aids in calcium absorption, which is vital for osteoporosis prevention Read Review. Others noted that its benefits are particularly important for individuals over 50-60 years, highlighting its contribution to overall bone health Read Review.
Regarding the specific dosage for osteoporosis treatment, users did not provide explicit dosage recommendations in their reviews. Instead, they praised the effectiveness of L-Lysine in supporting calcium absorption and maintaining bone density as part of a broad health regimen Read Review. L-Lysine's role in enhancing collagen synthesis further underscores its importance, making it a potential ally in osteoporosis management Read Review.
9
Boosts calcium absorption
Lysine contributes to muscle growth and fat metabolism, providing additional energy. Clinical studies affirm that this amino acid enhances calcium absorption, significantly aiding in the prevention and treatment of osteoporosis.
9
Prevents osteoporosis
Now Foods L-Lysine 500 mg is crucial for health. It aids immunity and helps prevent and treat yeast, fungal infections, and herpes due to its role in collagen synthesis. It's essential for calcium absorption, which is vital in preventing osteoporosis.
9
Improves calcium retention
2 people found this helpful
Lysine is essential for nutrient absorption and utilisation in the body. It enhances protein absorption, improves nutrition, and promotes growth. It aids in calcium absorption, which helps prevent osteoporosis and reduce triglyceride levels, thereby lowering cardiovascular disease risk.
9
Fat metabolism
L-lysine boosts muscle mass and fat metabolism while significantly improving calcium absorption, playing a key role in osteoporosis prevention.
7.5
Inhibits herpes simplex
Lysine inhibits the herpes simplex virus's growth and prevents related infections, such as cold sores. Additionally, it may help in preventing osteoporosis by enhancing calcium absorption and retention in the body.
7.5
Skin health benefits
1 people found this helpful
L-Lysine supports the immune system and helps in collagen production and calcium absorption, thus aiding in the prevention of osteoporosis.
7.5
Bone health support
91 people found this helpful
I take lysine before meals; it aids calcium absorption and is essential for preventing osteoporosis. I also give it to my cat battling a herpes virus, as it's effective for both us and our pets.
7.5
Joint health focus
132 people found this helpful
The drug enhances the elasticity of veins, increases venous tone, and improves calcium absorption, which helps in preventing osteoporosis, particularly in those over 50-60 years. It also promotes collagen synthesis.
7.5
Essential for osteoporosis
Excellent product! Lysine augments calcium absorption, which is vital for osteoporosis support, making it an essential part of my regimen.
9
Oral teriparatide shows promise
Enhanced oral absorption of teriparatide with therapeutic potential for management of osteoporosis.
Our study focused on creating a better way to deliver teriparatide, a treatment for osteoporosis, using l-lysine. We developed a solid oral formulation that significantly improved the absorption of the hormone compared to traditional injections. The results showed that this new method not only maintained similar effectiveness in stimulating bone growth but also led to improved bone density and thickness in lab mice with osteoporosis. Overall, we found that oral teriparatide could be a promising option for managing osteoporosis.
9.5
Oral PTH-Lysine complex enhances bone health
Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex.
We explored an innovative way to deliver the osteoporosis treatment parathyroid hormone (PTH) through oral microencapsulated complexes combined with L-lysine.
This approach enhances patient compliance compared to daily injections. Testing revealed that the oral formulation improved bioavailability and produced significant increases in bone density and volume in ovariectomized rats.
The findings suggest that this new method could be a promising option to improve bone health without the hassle of injections.
8
NSD2 inhibition may reduce osteoporosis
NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells.
We explored the connection between NSD2 and bone health, specifically how it affects bone marrow stem cells in osteoporosis. By using advanced techniques, we found that NSD2 inhibits the growth of these cells, which is crucial for healthy bones.
In animal models of osteoporosis, blocking NSD2 not only promoted stem cell differentiation but also helped prevent bone loss. Our findings suggest that targeting NSD2 could be a new way to treat osteoporosis and improve bone health.
References
He G, Ke Y, Yuan J, Zhang B, Dai L, et al. NSD2-mediated H3K36me2 exacerbates osteoporosis via activation of hoxa2 in bone marrow mesenchymal stem cells. Cell Signal. 2024;121:111294. doi:10.1016/j.cellsig.2024.111294
Subedi L, Pandey P, Kang SH, Kim KT, Cho SS, et al. Enhanced oral absorption of teriparatide with therapeutic potential for management of osteoporosis. J Control Release. 2022;349:502. doi:10.1016/j.jconrel.2022.07.012
Hwang SR, Seo DH, Byun Y, Park JW. Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex. Int J Nanomedicine. 2016;11:4231. doi:10.2147/IJN.S110573