'
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Theanine
200 mg
*
Inositol
100 mg
*

The product is found useful for the following medical conditions

Chronic Fatigue Syndrome

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 18 Reviews
8.8
9.5
Stress resistance
Most Useful Review
I regret not discovering L-theanine earlier. This amino acid, which I take daily, helps me combat chronic fatigue syndrome and stress. It effectively calms my mind, aiding in a protective mental state. I notice improvements in my cognitive functions, which are crucial at my age. Additionally, its neuroprotective properties support brain health and prevent age-related issues. I highly recommend combining L-theanine with caffeine for enhanced focus.

Depression

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
USERS' SCORE
Good
Based on 36 Reviews
8.8
8
Myo-inositol: Depression treatment potential
Cyclitols: From Basic Understanding to Their Association with Neurodegeneration.
Most Relevant Research
We explored the potential of inositol, particularly Myo-inositol (MI), as a treatment option for depression, especially in individuals dealing with neurodegenerative disorders. The literature suggests that MI and its derivatives are vital in various cellular functions, including signal transmission and osmoregulation.

While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.

However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
10
Alleviated anxiety
Most Useful Review
I developed anxiety and depression, leading to unclear thoughts and emotional eating. This supplement transformed my well-being. I now feel like my old self, with reduced anxiety and improved focus, enabling me to manage stress calmly. It has significantly improved my sleep and overall mood.

Menopause

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
USERS' SCORE
Good
Based on 17 Reviews
8.8
7
Myo-Inositol Support in Menopause
Tonsil-Derived Mesenchymal Stem Cell-Derived Small Extracellular Vesicles (sEVs) Restore Myo-Inositol Production in LPS-Treated Skeletal Muscle.
Most Relevant Research
We investigated whether small extracellular vesicles (sEVs) derived from human palatine tonsil mesenchymal stem cells could boost myo-inositol levels in the context of menopause. This was particularly interesting given that menopausal women are prone to chronic inflammation due to physiological changes and related issues like metabolic syndrome.

To explore this, we treated mice with lipopolysaccharides (LPS) to simulate inflammation and assessed how the inclusion of T-MSC sEVs influenced myo-inositol production. After treatment, we measured levels of proteins involved in inositol synthesis in skeletal muscle and checked the serum for inositol levels.

Our findings are encouraging and suggest that T-MSC sEVs might help mitigate some effects of chronic inflammation linked to menopause. By supporting skeletal muscle mass and maintaining myo-inositol levels, these sEVs could be an effective strategy for improving metabolic health in menopausal women. This study sheds light on a potential new approach to tackle metabolic disturbances during this life stage.
9.5
Improved sleep quality
Most Useful Review
I began taking this due to sleep issues during menopause that left me feeling unmotivated. Taking one tablet each morning made my head feel clearer, and my motivation returned. My sleep disturbances have improved significantly; I now wake up less during the night and feel refreshed in the morning. Daytime frustrations have also decreased. I will continue using this supplement.

Anxiety

SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.3
USERS' SCORE
Good
Based on 207 Reviews
8.7
8
Inositol reduces anxiety in hens
Dietary Inositol Reduces Fearfulness and Avoidance in Laying Hens.
Most Relevant Research
We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.

Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.

Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.

Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
9.5
Calmness achieved
Most Useful Review
I’ve noticed very positive effects; I cope with anxiety better, feel more confident, and remain calm. It positively influences my mood and helps concentration without causing drowsiness. I take it regularly; its effect is similar to that of good tea. I highly recommend it to everyone.

Cardiovascular Disease

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 9 Reviews
8.6
9
Inositol protects against cardiac damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.

The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.

Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
8.8
Support cardiovascular health
Most Useful Review
L-Theanine, an amino acid from green tea, promotes relaxation without drowsiness and supports the cardiovascular system. I've found it particularly effective when taken after a meal. Its effects are gradual, offering a soft sense of balance and clarity of thought without addiction or side effects. I've noticed no negative effects and consider it a noteworthy supplement that delivers on its promises.

High Cholesterol

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.6
9
Inositol boosts growth and health
Inositol Inclusion Affects Growth, Body Composition, Antioxidant Performance, and Lipid Metabolism of Largemouth Bass ().
Most Relevant Research
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.

Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.

Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.

Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
9.5
Effective relaxant
Most Useful Review
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.

Hypothyroidism

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Myo-inositol reduces thyroid nodule size
Evaluation of thyroid nodule characteristics in subclinical hypothyroid patients under a myo-inositol plus selenium treatment.
Most Relevant Research
We conducted an observational study to explore how myo-inositol (MI) combined with selenium (Se) impacts patients with subclinical hypothyroidism (SCH) and associated thyroid nodules (TNs).

Our research involved 642 patients suspected of having hypothyroidism, focusing on a subset with SCH. We divided them into two groups: one that received the MI plus Se treatment for six months and a control group that did not receive any treatment.

Among the received results, we found that the treatment group showed a significant reduction in the size and number of mixed TNs, alongside an improved elasticity score. Remarkably, TSH levels also dropped significantly after treatment, indicating a positive response. In contrast, the control group experienced an increase in TSH levels, highlighting the potential benefits of MI plus Se for managing symptoms of hypothyroidism.

These findings suggest promising avenues for further research, particularly regarding the role of inositol in thyroid health. While we observed substantial benefits in the treated group, we also emphasize the need for more extensive studies to confirm these effects and their mechanisms.
8.8
Improved concentration
Most Useful Review
I have hypothyroidism but enjoy coffee in the morning, paired with L-Theanine, which enhances the effect. Caffeine alone causes a sharp energy spike followed by a drop, whereas combining it with L-Theanine results in a smoother, longer-lasting boost in focus and mood. It aids my memory, suppresses appetite, and doesn’t induce drowsiness. Occasionally, I take it with melatonin at night to help me sleep, always on an empty stomach for greater potency. I love it and always keep it stocked!

Leg Cramps

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9.5
Relieved leg syndrome
Most Useful Review
This theanine has been my salvation during a stressful period at work. After taking magnesium before bedtime, I found it easier to sleep and wake up, and my restless legs syndrome at night disappeared.

Vertigo

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Reviews
8.6
9.5
Vertigo relief
Most Useful Review
I loved him from the first week. I've enjoyed excellent sleep and have woken up with a clear mind. The vertigo has ceased.

Liver Disease

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 1 Reviews
8.5
8
Myo-inositol improves insulin resistance
The effect of myo-inositol supplementation on AMPK/PI3K/AKT pathway and insulin resistance in patients with NAFLD.
Most Relevant Research
We conducted a double-blinded, placebo-controlled clinical trial to explore how myo-inositol (MI) influences insulin resistance (IR) among obese individuals with non-alcoholic fatty liver disease (NAFLD). Our study involved 48 participants who were randomly assigned to receive either 4 grams of MI or a placebo daily for eight weeks.

Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.

The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
8.8
Energy boost
Most Useful Review
A large package lasts me 4 months, perfect for an adult's full 6-month intake. The price-quality ratio is excellent! The capsules are small and easy to swallow, taken half an hour before breakfast. The main ingredient, theanine, effectively relaxes without causing drowsiness, boosting energy and alleviating depressive symptoms. This product also contains inositol, which helps lower bad cholesterol and prevents cardiovascular diseases, beneficial for addressing liver disease as well.

Bone Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.4
9.5
Healthy bone support
Most Useful Review
The quality is excellent, enhancing immunity with a generous dosage. It effectively addresses deficiencies and is very healthy. I'm pleased with my purchase; the size is convenient, and it supports bone strength. The packaging is user-friendly, especially since we receive so few vitamins from the sun, and the ingredients are superb.

Blood Clot

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
USERS' SCORE
Good
Based on 3 Reviews
8.2
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Most Relevant Research
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.

In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.

Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
8.3
Normalised blood pressure
Most Useful Review
I take this product with magnesium at night to aid my sleep. My blood pressure had risen, but thanks to the theanine, magnesium, and coQ10, my arrhythmia and blood pressure have normalised. This month's health check showed excellent results. I am pleased with both the quantity and quality, and as it is a reputable brand, I will continue using it.

Common Cold

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.2
9.5
Essential for colds
Most Useful Review
A fantastic product, essential if you suffer from recurring sore colds.

Heart Disease

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 25 Reviews
8.2
8
Inositol boosts heart protective adiponectin
Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia-reperfusion injury by elevating plasma adiponectin.
Most Relevant Research
Our research focused on understanding how inositol, specifically a molecule called 5-InsP7, plays a role in heart health by influencing levels of a substance called adiponectin. Adiponectin is important because it helps protect against cardiovascular issues and metabolic disorders.

We discovered that the enzyme inositol hexakisphosphate kinase 1 (IP6K1) produces 5-InsP7, which helps regulate how much adiponectin is available in the bloodstream. This regulation occurs through a process that ensures adiponectin stays stable instead of degrading within the cells.

When we decreased the levels of 5-InsP7—either by knocking out the gene responsible for producing it or through specific drug treatments—we noticed a significant increase in adiponectin levels in the plasma. This increase particularly favored the high molecular weight forms of adiponectin, which are particularly beneficial for heart protection.

The findings suggest that targeting 5-InsP7 could be a promising strategy for enhancing adiponectin levels, potentially offering a new avenue for protecting the heart against damage from conditions like ischemia-reperfusion injury, which occurs when blood flow returns to the heart after a period of blockage.

Overall, this study gives insight into how inositol treatment might help heart disease, emphasizing the importance of adiponectin in cardiovascular health.
9.5
Anxiety alleviation
Most Useful Review
L-theanine has greatly helped with my anxiety. Previously, my heart would race uncontrollably in stressful situations, but now I feel much calmer and can approach my day without that constant stress.

Tinnitus

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.1
6.8
Sleepy but relaxed
Most Useful Review
I've suffered from tinnitus for three months, fluctuating from a 6 to a 2 on a scale of 10. Despite no hearing loss, I'm exploring alternatives to medications like Xanax. After three weeks of taking this, I feel very sleepy but also quite relaxed. I hope it alleviates my bruxism and helps improve my tinnitus.

Autoimmune Disorder

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
5.6
USERS' SCORE
Good
Based on 10 Reviews
8
8
Myo-inositol enhances vitamin D effects
The impact of vitamin D on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in myo-inositol-treated and myo-inositol-naïve women with autoimmune thyroiditis: A pilot study.
Most Relevant Research
Our study aimed to explore the impact of myo-inositol treatment on thyroid autoimmunity in women with autoimmune thyroiditis. We included groups of women who had been on myo-inositol for a while and those who hadn’t. For six months, we observed how vitamin D supplementation interacted with myo-inositol in affecting thyroid health and immune responses.

We found that among participants taking myo-inositol, the addition of vitamin D significantly improved insulin sensitivity and led to better outcomes regarding thyroid antibodies. Specifically, women who were already on myo-inositol showed a greater reduction in thyroid peroxidase and thyroglobulin antibodies when vitamin D was added to their regimen.

Interestingly, the effects of vitamin D were less noticeable in women who weren't on myo-inositol. These individuals did not exhibit the same improvements in thyroid function or antibodies. Overall, the findings suggest that myo-inositol might enhance the benefits of vitamin D, indicating a potential synergistic effect between these two agents in managing autoimmune thyroiditis.
9.5
Improved mood evident
Most Useful Review
I have ordered theanine for my brother based on a doctor's advice. After a month, his condition has significantly improved; he seems happier and more aware. I highly recommend theanine as an effective treatment for those dealing with stress and cognitive issues.

Dizziness

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8
9.5
Sound sensitivity relief
Most Useful Review
I tried this due to my sensitivity to sound and light. After just one tablet, my hypersensitivity calmed down, and I felt a slight dizzy sensation, similar to anti-anxiety medication. I’m pleased it reduced my discomfort, and the capsules are easy to take. I’ll continue using this.

Insomnia

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 38 Reviews
8
9.5
Stress management
Most Useful Review
ALPHA waves in the sea of CALM or how to win STRESS! I regret not having iHERB and Theanine earlier; it could have saved my health! Now, Theanine is a vital supplement in my arsenal. It's well-known how stress depletes the body and drains energy. I take Theanine in my tea, and within 30-40 minutes, I feel STRESS-RESISTANT. It calms my mind and helps my cognitive functions, crucial at my age of 50. I highly recommend Theanine as an effective nootropic for cognitive support and stress relief.

Sleep Apnea

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 59 Reviews
7.9
9.5
Pain relief
Most Useful Review
I used to wake up with jaw aches, and my dentist informed me that I was clenching my teeth in my sleep, affecting my teeth. Since I began taking 400 mg of L-Theanine before bed, I no longer experience any pain!

Back Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.7
9.5
Effective relaxation
Most Useful Review
Microdosing L-theanine has been beneficial for my back pain caused by stress. Initially, I took it before bed, which didn’t help my sleep. I later found that taking one capsule in the morning and another in the evening, with green tea, promotes relaxation without causing drowsiness. The effect is reminiscent of MDMA microdosing; I feel a pleasant lightness and muscle relaxation. However, I advise against using it with alcohol as it can enhance intoxication.

Irritable Bowel Syndrome

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.5
8
Supplement improves IBS symptoms
Beta-glucan, inositol and digestive enzymes improve quality of life of patients with inflammatory bowel disease and irritable bowel syndrome.
Most Relevant Research
We explored how a mixture of beta-glucan, inositol, and digestive enzymes could alleviate gastrointestinal symptoms in patients with inflammatory bowel disease (IBD) and concurrent irritable bowel syndrome (IBS).

The study involved 43 patients who were already in clinical remission and treated only with mesalamine. They were divided into two groups: one received the usual treatment plus the supplement, while the other only received the standard care.

After four weeks, we observed notable improvements in symptoms such as bloating, flatulence, and abdominal pain in the group taking the supplement. Our findings suggest that this combination may significantly enhance the overall well-being of IBD-IBS patients, making their daily lives a bit easier.
7.5
Weight loss noted
Most Useful Review
I will purchase this product again! My digestion and bowel function have improved, and I've lost weight since taking it on an empty stomach, one or two daily. L-theanine, a unique amino acid in green tea, lowers anxiety and cortisol levels, thereby enhancing sleep quality. It's noted as beneficial in anti-aging and for calmness. I feel significantly less stressed and have lost weight, along with taking butyrate and EGCG preparations.

Pelvic Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.1
0
Jaw pain experienced
Most Useful Review
I experienced severe jaw pain after using this product for three days.

Headache

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 20 Reviews
6.9
9.5
Improved sleep
Most Useful Review
I have struggled with sleep disorders for years, relying on sleeping pills nightly. Even with 1.5 pills, I’d only sleep for 4-5 hours, waking with headaches and palpitations. After trying magnesium and theanine, my sleep improved remarkably. I managed to quit the pills and even adapt to afternoon naps. I am truly grateful.

Heart Attack

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
USERS' SCORE
Medium or Average
Based on 14 Reviews
6.2
9
ITPP enhances heart attack recovery
Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells.
Most Relevant Research
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.

Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.

In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.

Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
8.3
Normalised pulse
Most Useful Review
This is an excellent calming aid and has notably reduced my high heart rate. I take it nightly with bacopa, and I've been sleeping better, waking up less frequently. My pulse is now normal. I appreciate this product.
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