5/27/2025
Last update
5/27/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%
Top Medical Research Studies
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
Read More
4
Magnesium shows promise in thyroid recovery
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
Most Useful Reviews
9
Improved thyroid function
I suffer from hypothyroidism and know magnesium is vital for thyroid function, converting inactive T4 to active T3. I take one capsule of magnesium glycinate nightly and have noticed my leg cramps are gone. It's important to ensure adequate intake, particularly for those with hypothyroidism, and I'm grateful for its benefits when combined with other vitamins.
Read More
9
Positive absorption effects
Magnesium is crucial for our bodies, especially for those with hypothyroidism like me. I’ve struggled with absorption issues, but I've found relief by alternating between various forms of magnesium, which I now take without side effects. My health has significantly improved as magnesium supports crucial bodily functions, including the skeletal and nervous systems.
Read More
9
Heart function support
I highly recommend magnesium citrate for those with hypothyroidism. It’s easy to digest and has a mild laxative effect, helping manage gastrointestinal issues. This form of magnesium is essential for heart health and nerve function. My overall wellbeing has improved since I started taking it regularly.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
- All Researches
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
8
Magnesium shows potential benefits
We conducted a randomized double-blind study to see how supplementation with zinc, magnesium, and vitamin A might affect hypothyroidism.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
In our trial with 86 participants, those receiving the supplements showed improved thyroid function, indicated by a significant increase in serum FT4 levels.
However, no noteworthy changes were observed in the control group regarding thyroid hormones.
Overall, while the supplementation shows promise for some thyroid improvement, it's not a guaranteed solution for everyone.
Read More
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Read More
7
Minerals affect thyroid dysfunction risk
We delved into how different minerals might influence thyroid dysfunction, particularly focusing on hypothyroidism. Analyzing data from nearly 7,800 people, we utilized advanced statistical methods to explore the impact of mineral intake on thyroid hormones.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
Read More
4
Magnesium shows promise in thyroid recovery
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved thyroid function
I suffer from hypothyroidism and know magnesium is vital for thyroid function, converting inactive T4 to active T3. I take one capsule of magnesium glycinate nightly and have noticed my leg cramps are gone. It's important to ensure adequate intake, particularly for those with hypothyroidism, and I'm grateful for its benefits when combined with other vitamins.
Read More
9
Positive absorption effects
Magnesium is crucial for our bodies, especially for those with hypothyroidism like me. I’ve struggled with absorption issues, but I've found relief by alternating between various forms of magnesium, which I now take without side effects. My health has significantly improved as magnesium supports crucial bodily functions, including the skeletal and nervous systems.
Read More
9
Heart function support
I highly recommend magnesium citrate for those with hypothyroidism. It’s easy to digest and has a mild laxative effect, helping manage gastrointestinal issues. This form of magnesium is essential for heart health and nerve function. My overall wellbeing has improved since I started taking it regularly.
Read More
9
Heart rhythm stability
Since being diagnosed with hypothyroidism and taking medication, I've faced heart rate issues. I started taking magnesium daily, and it has significantly improved my heartbeat and rhythm. Additionally, it helps soothe my nerves. I find magnesium indispensable for my health and plan to continue using it.
Read More
9
Eased constipation issues
Hypothyroidism brings several challenges, including constipation. Adding magnesium to my daily regimen has made a significant difference in my life. The quality is excellent, and I'm pleased with its effects on my health.
Read More
Frequently Asked Questions
9
Improved thyroid function
I suffer from hypothyroidism and know magnesium is vital for thyroid function, converting inactive T4 to active T3. I take one capsule of magnesium glycinate nightly and have noticed my leg cramps are gone. It's important to ensure adequate intake, particularly for those with hypothyroidism, and I'm grateful for its benefits when combined with other vitamins.
7.5
Better sleep quality
I've been using magnesium from NOW, recommended by my endocrinologist for my hypothyroidism. It has notably improved my sleep quality, which has been poor. I will explore other forms of magnesium for future use. I'm grateful for this improvement.
9
Heart rhythm stability
Since being diagnosed with hypothyroidism and taking medication, I've faced heart rate issues. I started taking magnesium daily, and it has significantly improved my heartbeat and rhythm. Additionally, it helps soothe my nerves. I find magnesium indispensable for my health and plan to continue using it.
9
Heart function support
I highly recommend magnesium citrate for those with hypothyroidism. It’s easy to digest and has a mild laxative effect, helping manage gastrointestinal issues. This form of magnesium is essential for heart health and nerve function. My overall wellbeing has improved since I started taking it regularly.
9
Positive absorption effects
Magnesium is crucial for our bodies, especially for those with hypothyroidism like me. I’ve struggled with absorption issues, but I've found relief by alternating between various forms of magnesium, which I now take without side effects. My health has significantly improved as magnesium supports crucial bodily functions, including the skeletal and nervous systems.
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.
While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
9
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
4
Magnesium shows promise in thyroid recovery
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
7
Minerals affect thyroid dysfunction risk
We delved into how different minerals might influence thyroid dysfunction, particularly focusing on hypothyroidism. Analyzing data from nearly 7,800 people, we utilized advanced statistical methods to explore the impact of mineral intake on thyroid hormones.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
While we found that higher intakes of minerals like magnesium and calcium were linked to lower rates of hyperthyroidism, the study did not show significant benefits of magnesium specifically for hypothyroidism. The results suggest that a balanced intake of various minerals may support thyroid health overall.
References
- Nikkhah M, Vafa M, Abiri B, Golgiri F, Sarbakhsh P, et al. The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial. Med J Islam Repub Iran. 2024;38:133. 10.47176/mjiri.38.133
- Abbas AM, Sakr HF. Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. Can J Physiol Pharmacol. 2016;94:426. 10.1139/cjpp-2015-0247
- Moncayo R, Moncayo H. Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation. BBA Clin. 2015;3:113. 10.1016/j.bbacli.2014.12.005
- Liu S, Huang W, Lin Y, Wang Y, Li H, et al. Machine learning-based exploration of the associations between multiple minerals' intake and thyroid dysfunction: data from the National Health and Nutrition Examination Survey. Front Nutr. 2025;12:1522232. 10.3389/fnut.2025.1522232
- Rabbani E, Golgiri F, Janani L, Moradi N, Fallah S, et al. Randomized Study of the Effects of Zinc, Vitamin A, and Magnesium Co-supplementation on Thyroid Function, Oxidative Stress, and hs-CRP in Patients with Hypothyroidism. Biol Trace Elem Res. 2021;199:4074. 10.1007/s12011-020-02548-3
