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NOW Supplements Magnesium & Calcium
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.4
USERS' SCORE
Good
Based on 5 Reviews
8.5
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin D-3 (as Cholecalciferol)
25 mcg (1,000 IU)
125%
Calcium (from Aquamin® TG Seaweed Derived Minerals and Calcium Citrate)
400 mg
31%
Magnesium (from Magnesium Oxide, Magnesium Glycinate, Magnesium Taurinate, Magnesium Citrate and Aquamin® TG Seaweed Derived Minerals)
800 mg
190%
Zinc (from L-OptiZinc® Monomethionine)
15 mg
136%

Top Medical Research Studies

9
Magnesium reduces migraine symptoms
Magnesium and Migraine.
Highly relevant to magnesium effects
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Zinc reduces migraine symptoms
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women.
Highly relevant to migraine treatment
This study was designed as a randomized double-blind, placebo-controlled trial to examine how zinc gluconate supplementation might alleviate migraine symptoms in adult women. We followed 60 women, averaging about 35 years old, who either received 15 mg of zinc per day or a placebo for a duration of 12 weeks.

Over the trial, we observed significant improvements in those taking zinc. The frequency of migraine attacks, as well as the duration and severity of the headaches, drastically decreased for participants receiving zinc. We used various assessments, such as a numerical rating scale and the Migraine Disability Assessment test, to evaluate these changes.

Additionally, zinc supplementation showed a notable reduction in levels of low-density lipoprotein (LDL) cholesterol and high-sensitivity C-reactive protein (hs-CRP), both of which are associated with inflammation. However, no significant changes in triglycerides or high-density lipoprotein (HDL) levels were seen. After taking initial values into account, the changes in lipid levels and hs-CRP weren’t significant.

Overall, we found that zinc supplementation can beneficially impact migraine symptoms, reducing their severity and frequency among women. This offers a promising direction for migraine management without the side effects often associated with traditional medications.
Read More
8
Magnesium aids migraine prevention
Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur.
High relevance to magnesium use
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More

Most Useful Reviews

7.5
Effective for prevention
I take these daily as part of my migraine prevention regime. They are large but not difficult to swallow. Since starting them, my migraines have become noticeably lighter. However, when I stopped after six months, my migraines began to worsen again.
Read More
9.5
Helps with migraines
Excellent! I absolutely love this magnesium! It has assisted me with constipation and migraines. I sleep remarkably well at night, almost as if I’m taking sleeping pills.
Read More
8.8
Eases migraine severity
I purchase this product for my son, who has used it for years. He takes it occasionally for his migraines, and it appears to ease their severity. The formulation with a reverse ratio of magnesium and calcium ingredients seems to be the best for this purpose.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.4
  • All Researches
9.5
Zinc may alleviate migraines
A new horizon into the pathobiology, etiology and treatment of migraine.
Study combines zinc with supplements.
We embarked on an investigation into the potential of zinc as a treatment for migraines. The study involved 30 migraine sufferers who were given 75 mg of zinc sulfate daily for six weeks, along with vitamin B-complex and vitamin A or E during the first ten days.

Remarkably, this combination led to a significant improvement in most participants, suggesting that zinc could play a vital role in alleviating migraine symptoms. Zinc's effectiveness may stem from its essential functions in various biological processes, such as supporting the nervous system and regulating mineral balance in the body.

However, it’s important to note that the research combined zinc with other supplements, which makes it challenging to ascertain zinc's isolated effect on migraines. Future studies may benefit from a more controlled approach—perhaps comparing zinc against a placebo or examining its impact in larger groups.

Overall, this exploration opens new avenues for understanding how zinc and other nutrients can contribute to migraine relief, but further research is needed to fully validate these findings.
Read More
9
Magnesium reduces migraine symptoms
Magnesium and Migraine.
Highly relevant to magnesium effects
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Magnesium significantly alleviates migraines
Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.
Highly relevant effects of magnesium.
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More
9
Effective magnesium treatment for migraines
Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy.
High relevance: significant findings
We examined how magnesium oxide (MgO), both alone and with riboflavin, helps prevent migraines in pregnant individuals. This retrospective study included 203 patients treated between 2015 and 2020, analyzing outcomes such as migraine frequency, severity, and duration.

We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
Read More
9
Zinc reduces migraine symptoms
Assessing the Effect of Zinc Supplementation on the Frequency of Migraine Attack, Duration, Severity, Lipid Profile and hs-CRP in Adult Women.
Highly relevant to migraine treatment
This study was designed as a randomized double-blind, placebo-controlled trial to examine how zinc gluconate supplementation might alleviate migraine symptoms in adult women. We followed 60 women, averaging about 35 years old, who either received 15 mg of zinc per day or a placebo for a duration of 12 weeks.

Over the trial, we observed significant improvements in those taking zinc. The frequency of migraine attacks, as well as the duration and severity of the headaches, drastically decreased for participants receiving zinc. We used various assessments, such as a numerical rating scale and the Migraine Disability Assessment test, to evaluate these changes.

Additionally, zinc supplementation showed a notable reduction in levels of low-density lipoprotein (LDL) cholesterol and high-sensitivity C-reactive protein (hs-CRP), both of which are associated with inflammation. However, no significant changes in triglycerides or high-density lipoprotein (HDL) levels were seen. After taking initial values into account, the changes in lipid levels and hs-CRP weren’t significant.

Overall, we found that zinc supplementation can beneficially impact migraine symptoms, reducing their severity and frequency among women. This offers a promising direction for migraine management without the side effects often associated with traditional medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective for prevention
I take these daily as part of my migraine prevention regime. They are large but not difficult to swallow. Since starting them, my migraines have become noticeably lighter. However, when I stopped after six months, my migraines began to worsen again.
9.5
Helps with migraines
Excellent! I absolutely love this magnesium! It has assisted me with constipation and migraines. I sleep remarkably well at night, almost as if I’m taking sleeping pills.
8.8
Eases migraine severity
I purchase this product for my son, who has used it for years. He takes it occasionally for his migraines, and it appears to ease their severity. The formulation with a reverse ratio of magnesium and calcium ingredients seems to be the best for this purpose.
8.8
Decreases migraine frequency
I take this for migraine prevention, and I feel that they occur less frequently now.
8
Reduces migraines
I initially purchased a large bottle for my mother and later bought a smaller one. She is pleased and takes it with vitamin D and omega supplements. She has noticed improvements in her nail and hair growth, as well as a reduction in migraines.
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