Magnesium supplementation shows promiseTreatment of Resistant Acne Vulgaris in Adolescents Using Dietary Supplementation with Magnesium, Phosphate and Fatty Acids (Omega 6 and 7): Comparison with 13-Cis-Retinoic Acid.
Relevant results highlight efficacy
We examined how dietary supplementation with magnesium, among other nutrients, could help treat acne vulgaris. In a six-month study, one group received this natural supplement while another was given isotretinoin.
Notably, all participants in the magnesium group reported complete regression of their symptoms, contrasting with 68% in the isotretinoin group. This significant difference suggests that magnesium can be highly effective for acne treatment, offering a promising alternative with fewer side effects.
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This study looks into how mesoporous magnesium carbonate (MMC) can help with acne by reducing bacteria that thrive on our skin. We used a specific Gram-positive bacterium considered a common culprit in acne lesions. To ensure our results were reliable, we measured bacterial activity using a metabolic assay.
Our findings revealed that MMC exhibits a strong antibacterial effect against this acne-related bacterium. A significant factor contributing to its effectiveness is the material's alkalinity. This suggests that MMC could be developed further as a skincare ingredient aimed at inhibiting bacterial growth, providing an alternative to traditional antibiotic treatments.
Overall, we see promising potential for MMC in topical applications, especially for those looking for non-antibiotic solutions to manage acne and maintain skin health.
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MAP reduces acne inflammationMagnesium Ascorbyl Phosphate Regulates the Expression of Inflammatory Biomarkers in Cultured Sebocytes.
High relevance to magnesium's effect
We explored how magnesium ascorbyl phosphate (MAP), a stable form of vitamin C, can impact the inflammatory processes associated with acne. Our study focused on cultured sebocytes, the skin cells that produce sebum, and examined how they respond to both MAP and lipopolysaccharide (LPS), a substance known to trigger inflammation.
Using methods such as reverse transcription-polymerase chain reaction and enzyme-linked immunosorbent assay, we evaluated how these treatments affected the expression of inflammatory markers, cytokines, and other related proteins. Surprisingly, we found that while LPS increased inflammation, the introduction of MAP either by itself or in combination with LPS significantly reduced this inflammatory response.
Additionally, lipid peroxidation, a marker of oxidative stress, was notably lowered after applying MAP. This suggests that MAP not only helps reduce inflammation but might also combat oxidative damage in skin cells related to acne.
Overall, our findings suggest that MAP could be a promising alternative treatment strategy for managing acne and its associated inflammation.
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Magnesium's potential in acne treatmentAssociation of Myo-Inositol and Microlipodispersed Magnesium in Androgen-Dependent Dermatological Diseases: A Retrospective Study.
Relevant findings, future research needed
We explored how the combination of myo-inositol and microlipodispersed magnesium can help manage acne in women with polycystic ovary syndrome (PCOS). Over a six-month period, we observed improvements in acne severity and related symptoms after administering a specific nutraceutical formulation, LEVIGON™.
Patients experienced significant reductions in body mass index and hormone levels associated with acne, and their quality of life improved. Importantly, no side effects were reported, ensuring high compliance with the treatment. However, we recommend further research for long-term confirmation of these findings.
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Magnesium's relationship with acneSerum Macroelement and Microelement Concentrations in Patients with Polycystic Ovary Syndrome: a Cross-Sectional Study.
Connection noted but not proven
In our study, we explored the connection between magnesium levels and acne in women with polycystic ovary syndrome (PCOS). We involved 1137 women, analyzing their serum levels of macroelements and microelements through established blood tests. Our findings revealed that PCOS patients who experienced acne had higher magnesium levels compared to those without acne.
However, while we noted this increase, it’s important to clarify that we did not directly assess the effects of magnesium treatment on acne. Therefore, we cannot definitively conclude that increasing magnesium would improve acne outcomes. This insight leads us to consider magnesium's potential role in acne but also highlights the need for further research to establish a clear causal link between magnesium treatment and acne improvement.
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