' 
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Magnesium (elemental) (from 2,667 mg Magnesium Citrate)
400 mg
95%
Top Medical Research Studies
9
Magnesium aids menopause-related issues
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
Strong relevance to menopause research
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
7
Magnesium impacts menopause bone health
Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.
Significant findings on bone health
We explored the relationship between magnesium intake and bone health in postmenopausal black South African women over a two-year period. In this study, which included 144 participants, researchers measured bone mineral density (BMD) at several key sites, alongside various biochemical analyses, including bone turnover markers.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
The findings highlighted that higher dietary magnesium intake was linked to lower levels of C-Telopeptide of type I collagen (CTX-1), indicating reduced bone resorption. Moreover, calcium intake showed a positive correlation with BMD at the distal radius both at the start and end of the study.
Interestingly, one dietary pattern—snacking—also related to BMD scores over time, suggesting that what we eat can influence our bone health as we age. The results revealed that magnesium intake alone predicted a notable portion of the changes in bone turnover, emphasizing its potential role in supporting bone health during menopause.
Overall, this study suggests that paying attention to magnesium in our diets could be beneficial for women navigating menopause, especially regarding bone health.
Read More
7
Magnesium's limited effectiveness on menopause
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a systematic review.
Moderate relevance; mixed findings
We reviewed various studies to understand how magnesium and other dietary supplements like B vitamins and essential fatty acids affect stress and anxiety in women. Our search included women aged 18 and older who had their stress levels assessed.
Although magnesium showed potential benefits, particularly in combination with vitamin B6 for premenstrual anxiety, the results overall suggested limited effectiveness in managing menopause-related anxiety when evaluated across all studies.
We found that essential fatty acids could help reduce stress during pregnancy and menopause, but more research is needed to establish more definitive findings.
Although magnesium showed potential benefits, particularly in combination with vitamin B6 for premenstrual anxiety, the results overall suggested limited effectiveness in managing menopause-related anxiety when evaluated across all studies.
We found that essential fatty acids could help reduce stress during pregnancy and menopause, but more research is needed to establish more definitive findings.
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Most Useful Reviews
9.5
Less irritable feeling.
I recommend it! I purchased magnesium for its benefits on depression and irritability during menopause. After starting it, I felt less depressed and irritable, enabling me to live more comfortably. My mother had severe menopausal symptoms, but if taking magnesium can alleviate my fears about menopause, I’m delighted! I appreciate the capsule size as well, making it easy to take.
Read More
9.5
Mood improved significantly.
I found it quite good! I’ve purchased this multiple times after reading about magnesium deficiency. My mood, previously a bit low, improved from the second day of intake, and irritability vanished. I initially thought this was just a symptom of menopause, yet it allowed me to live peacefully. I plan to reorder when it runs out.
Read More
9.5
Better sleep reported.
Great product and price! The coated tablets are easy to swallow, which is important during menopause. They help with muscle tightness. I began with one to see if it assisted my sleep, and now I take up to three on occasion. Since I stopped using sleeping pills and melatonin, sleep improves significantly after taking these.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
- All Researches
9
Magnesium aids menopause-related issues
The Causal Role of Magnesium Deficiency in the Neuroinflammation, Pain Hypersensitivity and Memory/Emotional Deficits in Ovariectomized and Aged Female Mice.
Strong relevance to menopause research
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
Read More
9
Magnesium's impact on bone health
Supplementation of nanofiltrated deep ocean water ameliorate the progression of osteoporosis in ovariectomized rat via regulating osteoblast differentiation.
Study shows mixed magnesium benefits
Our exploration centered on the effects of magnesium, particularly from nanofiltrated deep ocean water (DOW), in addressing osteoporosis, a common concern during menopause. In our study, we used ovariectomized female Sprague-Dawley rats, a model that simulates menopausal conditions. We administered varying amounts of DOW daily over eight weeks to observe its impact on bone health.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
We found that DOW supplementation significantly increased bone density and reduced bone loss related to menopause. This was particularly notable as the rats that received DOW showed improved bone structure and reduced adiposity in their bones. More specifically, the lowest doses of DOW led to increased expression of a key protein called RUNX2, which plays an essential role in the formation of bone cells known as osteoblasts.
In human osteoblasts, DOW also raised levels of osteocalcin and alkaline phosphatase—both vital for promoting bone health. Overall, our findings demonstrated that magnesium-rich DOW can enhance osteoblast differentiation, contributing positively to bone structure integrity during menopause. This work highlights how incorporating magnesium into our diets or supplements could be beneficial for bone health as we age.
Read More
9
Isoflavones, probiotics boost bone health
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial.
Evidence-based findings on menopause treatment
We explored the impact of a novel red clover extract rich in isoflavones and probiotics on bone health in postmenopausal osteopenic women. In a year-long double-blind trial with 78 participants, we compared this treatment alongside standard supplements against a placebo. Results showed that the extract substantially reduced bone mineral density loss and improved certain estrogen metabolism markers. However, it did not affect other bone turnover indicators significantly. Overall, combining the extract with calcium and magnesium proved beneficial for bone health in this demographic.
Read More
9
Magnesium reduces menopause symptoms
Effects of a new combination of nutraceuticals on postmenopausal symptoms and metabolic profile: a crossover, randomized, double-blind trial.
High relevance to menopause treatment
We explored the effects of a nutraceutical blend, including magnesium, on menopause symptoms through a crossover trial involving 43 postmenopausal women.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
Participants experienced significant reductions in menopause symptoms, as measured by the Menopause Rating Scale, after using the nutraceuticals.
Additionally, improvements were noted in cardiovascular risk factors, such as lower cholesterol levels and blood pressure.
Overall, this study suggests that magnesium, combined with other nutrients, may provide meaningful relief for postmenopausal symptoms.
Read More
7
Magnesium aids menopausal metabolism
Utilizing a Combination of Supplements Comprising Boric Acid, Magnesium, Vitamin D3, and Extra Virgin Olive Oil to Improve Metabolism in Menopausal Ovariectomized Rats.
Combination treatment limits specificity
We conducted a study to understand how magnesium, along with other supplements, could influence metabolic health during menopause. Our research involved 42 adult female rats that were either ovariectomized or kept as controls. We divided them into seven groups to assess the effects of various treatments, including magnesium, boric acid, vitamin D3, extra virgin olive oil, and combinations of these supplements.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
The results were promising. We observed significant improvements in markers related to inflammation, oxidative stress, and various metabolic parameters when magnesium was included in the treatment plans. Interestingly, the rats receiving magnesium, especially as part of a combined treatment, showed better results than those given individual supplements. This suggests that magnesium could play a valuable role in supporting metabolic health during menopause.
However, it’s worth noting that while magnesium demonstrated beneficial effects, the comprehensive impact of each supplement used individually wasn’t singled out for analysis. Thus, while magnesium appears to contribute positively, we cannot decisively state its specific role in isolation. Overall, our findings hint at a promising therapeutic potential for magnesium in managing menopausal symptoms, particularly when used alongside other beneficial nutrients.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Less irritable feeling.
I recommend it! I purchased magnesium for its benefits on depression and irritability during menopause. After starting it, I felt less depressed and irritable, enabling me to live more comfortably. My mother had severe menopausal symptoms, but if taking magnesium can alleviate my fears about menopause, I’m delighted! I appreciate the capsule size as well, making it easy to take.
Read More
9.5
Mood improved significantly.
I found it quite good! I’ve purchased this multiple times after reading about magnesium deficiency. My mood, previously a bit low, improved from the second day of intake, and irritability vanished. I initially thought this was just a symptom of menopause, yet it allowed me to live peacefully. I plan to reorder when it runs out.
Read More
9.5
Better sleep reported.
Great product and price! The coated tablets are easy to swallow, which is important during menopause. They help with muscle tightness. I began with one to see if it assisted my sleep, and now I take up to three on occasion. Since I stopped using sleeping pills and melatonin, sleep improves significantly after taking these.
Read More
7.5
Symptoms alleviated overall.
The drug was recommended by my doctor. The benefits of magnesium citrate include providing energy to cells and commencing necessary biochemical processes. It effectively addresses sleep disorders and digestive issues while relieving menstruation and menopause symptoms. Overall, my health has improved, leading to calmness and better sleep.
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7.3
Notable improvement
Good magnesium. I've ordered it before and take two capsules at night. Now, during menopause, I can feel the noticeable effects of the supplement.
