Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Magnesium (elemental) (from 2,667 mg Magnesium Citrate)
400 mg
95%

Top Medical Research Studies

We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.

The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
We conducted a multicenter crossover study to see if magnesium alginate could alleviate reflux symptoms in infants. A total of 72 infants participated, receiving either magnesium alginate or a thickened formula in alternating phases.

Our findings showed a significant reduction in reflux symptoms across all infant groups. However, there was no significant difference in effectiveness between the two treatments. Importantly, using magnesium alginate also yielded cost savings of about €4.60 per infant compared to the thickened formula.

Thus, magnesium alginate appears to be a cost-effective option without sacrificing symptom relief.
7
Gaviscon® Advance effectively treats LPR
We explored the effectiveness of Gaviscon® Advance, both alone and alongside proton pump inhibitors (PPIs), in treating laryngopharyngeal reflux (LPR).

One hundred patients participated in this study, all treated with Gaviscon® Advance and monitored over three months.

The findings indicated that while Gaviscon® Advance is effective on its own, combining it with a high-dose PPI did not enhance symptom relief.

This suggests that Gaviscon® Advance can be a sufficient treatment for LPR without needing the added PPI.

Most Useful Reviews

9
Reduced reflux discomfort
45 people found this helpful
Good evening, we are from Ukraine! I wish you all the best in this challenging time. This magnesium was prescribed by my doctor, so I take three capsules before bedtime as directed. The capsules are large, necessitating plenty of water. My gastrointestinal tract has improved, and the reflux gastritis has ceased to trouble me. My nervousness during PMS has also disappeared.
9
Effective for reflux
This is a great supplement for my reflux issue. It noticeably reduces discomfort and pain in my body, making me feel much better overall.
9
No reflux issues
This great product is easy to take and has significantly improved my experience. I have not experienced any reflux or unpleasant aftertaste.

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
  • All Researches
9.5
Gaviscon DA effectively neutralizes acid
We explored how Gaviscon Double Action, a combination of alginate and antacid, affects gastric acid levels. In a carefully designed crossover study, we monitored intragastric pH in healthy volunteers after administering Gaviscon DA versus a placebo.

The results showed a clear advantage for Gaviscon DA, with pH levels reaching 4 or higher nearly 47% of the time, compared to just 5% for the placebo. This confirms that Gaviscon DA effectively neutralizes gastric acid, enhancing the understanding of how its components work together for reflux relief.
9
Banxia Houpu Decoction shows promise
We evaluated how Banxia Houpu Decoction, a traditional Chinese remedy, can help patients with refractory gastroesophageal reflux disease (RGERD). In our study involving 89 patients, we compared this decoction to standard Western treatments, including proton pump inhibitors with added magnesium aluminum carbonate.

Results showed that the decoction significantly improved throat burning, swallowing difficulties, and hiccups more effectively than Western treatments. However, the Western medicine group had better relief for heartburn and gastric burning sensations.

Factors like age and gastroesophageal flap valve grade also impacted treatment effectiveness.
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.

The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
We aimed to observe how effective Weisu granules are on laryngopharyngeal reflux by randomly assigning 180 patients into three groups.

The experimental group received a combination of Lanqin oral solution and Weisu granules, while the control groups used either Lanqin alone or Esomeprazole with Lanqin.

After four weeks, the experimental group showed a remarkable 91.7% improvement, much higher than the 73.3% in control group A. Although the experimental group differed significantly from control group A, results were similar to control group B, indicating no major advantage over Esomeprazole.
8
GutGard® shows promise for GER
We evaluated how GutGard®, a specific liquorice extract, impacts symptoms of gastroesophageal reflux (GER) compared to a placebo. In a well-structured study, participants were randomly assigned to either a GutGard® group or a placebo group for 28 days.

Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced reflux discomfort
45 people found this helpful
Good evening, we are from Ukraine! I wish you all the best in this challenging time. This magnesium was prescribed by my doctor, so I take three capsules before bedtime as directed. The capsules are large, necessitating plenty of water. My gastrointestinal tract has improved, and the reflux gastritis has ceased to trouble me. My nervousness during PMS has also disappeared.
9
Effective for reflux
This is a great supplement for my reflux issue. It noticeably reduces discomfort and pain in my body, making me feel much better overall.
9
No reflux issues
This great product is easy to take and has significantly improved my experience. I have not experienced any reflux or unpleasant aftertaste.
7.5
Relieved reflux pain
I used Magnesium St when I experienced esophageal reflux, and it helped relieve my pain and tighten my muscles effectively. It is truly fantastic as it aids in deep sleep, assists in fat burning, and regulates everything. "Awesome" is an understatement.
8
Less nervous tension
4 people found this helpful
I highly recommend this! After taking it for ten days, I noticed a positive effect on my nervous tension from the very first day. I'm feeling more relaxed and no longer clench my jaw as tightly since introducing this supplement. The capsule is quite large, but it’s easy to swallow and does not cause reflux or discomfort.

Frequently Asked Questions

8
Less nervous tension
4 people found this helpful
I highly recommend this! After taking it for ten days, I noticed a positive effect on my nervous tension from the very first day. I'm feeling more relaxed and no longer clench my jaw as tightly since introducing this supplement. The capsule is quite large, but it’s easy to swallow and does not cause reflux or discomfort.
7.5
Improved digestion
I take these capsules with each meal, and I've noticed a significant difference. There is less acid reflux, more regularity, and reduced bloating as well.
9
Effective for reflux
This is a great supplement for my reflux issue. It noticeably reduces discomfort and pain in my body, making me feel much better overall.
7.5
Relieved reflux pain
I used Magnesium St when I experienced esophageal reflux, and it helped relieve my pain and tighten my muscles effectively. It is truly fantastic as it aids in deep sleep, assists in fat burning, and regulates everything. "Awesome" is an understatement.
9
Reduced reflux discomfort
45 people found this helpful
Good evening, we are from Ukraine! I wish you all the best in this challenging time. This magnesium was prescribed by my doctor, so I take three capsules before bedtime as directed. The capsules are large, necessitating plenty of water. My gastrointestinal tract has improved, and the reflux gastritis has ceased to trouble me. My nervousness during PMS has also disappeared.
9
No reflux issues
This great product is easy to take and has significantly improved my experience. I have not experienced any reflux or unpleasant aftertaste.
8
GutGard® shows promise for GER
We evaluated how GutGard®, a specific liquorice extract, impacts symptoms of gastroesophageal reflux (GER) compared to a placebo. In a well-structured study, participants were randomly assigned to either a GutGard® group or a placebo group for 28 days.

Our findings suggest that those taking GutGard® experienced quicker relief from symptoms like heartburn and regurgitation, showing improvements within just two weeks. This indicates that GutGard® could be an effective option for managing GER symptoms.
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.

The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
8
Gaviscon Advance outperforms antacid treatment
We investigated whether Gaviscon Advance or a non-alginate antacid was more effective at reducing acid reflux risk in obese individuals after late-night meals. In a clinical trial, participants were randomly assigned to receive one of the two medications after dinner.

Findings showed that Gaviscon Advance significantly suppressed the acid pocket and reduced symptoms like regurgitation better than the non-alginate antacid. This suggests that Gaviscon Advance may be a better treatment option for obesity-related reflux following late-night eating.

References

  1. Raj JP, Saxena U, Belhekar MN, Mamde A, Darak H, et al. Efficacy and Safety of GutGard® in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial. Complement Med Res. 2025;32:26. doi:10.1159/000543367
  2. Song S, Zhang Y, Zhang J, Jiang Y, Gong A. Efficacy evaluation and exploratory analysis of influencing factors of Banxia Houpu Decoction in the treatment of refractory gastroesophageal reflux disease. Medicine (Baltimore). 2024;103:e38045. doi:10.1097/MD.0000000000038045
  3. Pizzorni N, Ambrogi F, Eplite A, Rama S, Robotti C, et al. Magnesium alginate versus proton pump inhibitors for the treatment of laryngopharyngeal reflux: a non-inferiority randomized controlled trial. Eur Arch Otorhinolaryngol. 2022;279:2533. doi:10.1007/s00405-021-07219-0
  4. Ciprandi G, Damiani V, Passali FM, Crisanti A, Motta G, et al. Magnesium alginate in patients with laryngopharyngeal reflux. J Biol Regul Homeost Agents. 2021;35:61. doi:10.23812/21-1supp2-12
  5. Deraman MA, Abdul Hafidz MI, Lawenko RM, Ma ZF, Wong MS, et al. Randomised clinical trial: the effectiveness of Gaviscon Advance vs non-alginate antacid in suppression of acid pocket and post-prandial reflux in obese individuals after late-night supper. Aliment Pharmacol Ther. 2020;51:1014. doi:10.1111/apt.15746
  6. Dragomiretska NV, Babov KD, Gushcha SG, Zabolotna IB, Plakida AL, et al. Application of mineral waters in the complex treatment of patients with gastroesophageal reflux disease. Minerva Gastroenterol Dietol. 2020;66:225. doi:10.23736/S1121-421X.20.02601-X
  7. Baldassarre ME, Di Mauro A, Pignatelli MC, Fanelli M, Salvatore S, et al. Magnesium Alginate in Gastro-Esophageal Reflux: A Randomized Multicenter Cross-Over Study in Infants. Int J Environ Res Public Health. 2019;17. doi:10.3390/ijerph17010083
  8. Wilkinson J, Abd-Elaziz K, den Daas I, Wemer J, van Haastert M, et al. Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action). Drug Dev Ind Pharm. 2019;45:430. doi:10.1080/03639045.2018.1546314
  9. Wilkie MD, Fraser HM, Raja H. Gaviscon® Advance alone versus co-prescription of Gaviscon® Advance and proton pump inhibitors in the treatment of laryngopharyngeal reflux. Eur Arch Otorhinolaryngol. 2018;275:2515. doi:10.1007/s00405-018-5079-0
  10. Zhuang XY, Yang HZ, Wang HG, Li CW. [Clinical observation of Weisu granules in treating laryngopharyngeal reflux]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018;32:369. doi:10.13201/j.issn.1001-1781.2018.05.012
  11. Bianchetti M, Peralta S, Nicita R, Aragona SE, Ciprandi G. Emerging from gastroesophageal reflux (EMERGE): An Italian survey - II the viewpoint of the patient. J Biol Regul Homeost Agents. 2018;32:983.
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