We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
Read More
7
Magnesium may ease tinnitus symptoms
Phase 2 study examining magnesium-dependent tinnitus.
We set out to understand whether magnesium supplementation could help alleviate tinnitus, a persistent ringing or noise in the ears that affects many individuals. In our study, we observed 26 patients who were experiencing moderate to severe tinnitus symptoms. Over three months, participants took a daily dose of 532 mg of magnesium and reported their tinnitus severity using a simple scale.
Patients rated their tinnitus distress each day, while also completing a standardized questionnaire at the beginning and end of the study. This approach allowed us to gather direct feedback from participants about their experiences with magnesium. After analyzing the results, it became clear that magnesium might indeed have a positive effect on reducing the perceived handicap associated with tinnitus.
Although we did not use a placebo group for this exploratory phase, the findings suggest there could be real potential for magnesium as a supportive treatment for those struggling with tinnitus. It’s encouraging to think that something as common as magnesium, often lacking in many diets, could make a difference for individuals dealing with this challenging condition.
Read More
9
Magnesium's potential in tinnitus treatment
Receptor pharmacological models for inner ear therapies with emphasis on glutamate receptors: a survey.
We explored the potential of magnesium as a treatment for tinnitus, a condition characterized by persistent ringing or buzzing in the ears. The research indicates that magnesium may have protective effects on inner ear health, particularly in the context of glutamate neurotoxicity, which is believed to contribute to hearing loss and tinnitus.
The study highlights that magnesium, along with other compounds like Caroverine, has shown statistically significant benefits in treating noise-induced hearing loss and tinnitus. However, it's essential to note that while these findings are promising, the specific effects of magnesium alone in isolated situations require further investigation before we can definitively recommend its use for tinnitus.
Overall, this research invites us to be optimistic but cautious. As we continue to search for effective therapies for tinnitus, magnesium might be one tool in our toolbox, but more studies are needed to fully understand its mechanisms and effectiveness.
Read More
Most Useful Reviews
9
Prevented tinnitus convulsions
Excellent! I experienced symptoms of magnesium deficiency, including sleep disturbances and convulsions, which alarmed me. After consulting my doctor, I’ve been taking magnesium citrate. I start with six capsules daily due to my high physical activity, gradually reducing it when feeling better. My symptoms, including tinnitus, have normalised, and the packaging is convenient.
Read More
7.5
Reduced tinnitus noise
Not the first time I’ve bought for the family. I take it twice a day with meals. My husband was initially sceptical about magnesium, but after experiencing high blood pressure and irritability, he noticed improvements after a month of taking it. His blood pressure is now normal, and symptoms like tinnitus and neck throbbing have disappeared. For me, magnesium is essential for brain nourishment and calmness. I take breaks during holidays before resuming.
Read More
7.5
Improved tinnitus symptoms
I used to suffer from tinnitus, but now the symptoms have diminished significantly and last for longer periods of time.
We explored the potential of magnesium as a treatment for tinnitus, a condition characterized by persistent ringing or buzzing in the ears. The research indicates that magnesium may have protective effects on inner ear health, particularly in the context of glutamate neurotoxicity, which is believed to contribute to hearing loss and tinnitus.
The study highlights that magnesium, along with other compounds like Caroverine, has shown statistically significant benefits in treating noise-induced hearing loss and tinnitus. However, it's essential to note that while these findings are promising, the specific effects of magnesium alone in isolated situations require further investigation before we can definitively recommend its use for tinnitus.
Overall, this research invites us to be optimistic but cautious. As we continue to search for effective therapies for tinnitus, magnesium might be one tool in our toolbox, but more studies are needed to fully understand its mechanisms and effectiveness.
Read More
8
Magnesium may alleviate tinnitus symptoms
AUDISTIM Day/Night Alleviates Tinnitus-Related Handicap in Patients with Chronic Tinnitus: A Double-Blind Randomized Placebo-Controlled Trial.
We explored the effectiveness of a daily supplement called AUDISTIM Day/Night, which includes magnesium along with various vitamins and phytochemicals, in reducing tinnitus-related challenges. Conducted as a double-blind randomized placebo-controlled trial, our research involved 114 adults with mild to severe tinnitus, looking at how this supplement might alleviate their symptoms over three months.
Our findings showed that those taking the AUDISTIM supplement experienced a more significant reduction in tinnitus handicap compared to those on a placebo. In fact, participants with continuous tinnitus reported even greater improvements. While both groups noticed some enhancements in sleep quality, it was only the group taking AUDISTIM that showed reduced psychological stress.
This study suggests that the combination of active compounds, including magnesium, could be beneficial in managing tinnitus symptoms. It aligns well with previous observations in real-life settings and offers a promising new avenue for those suffering from this challenging condition.
Read More
8
Tinnitan Duo® aids tinnitus relief
Effectiveness of Tinnitan Duo® in Subjective Tinnitus with Emotional Affectation: A Prospective, Interventional Study.
We looked into the effectiveness of a specific food supplement, Tinnitan Duo®, which contains magnesium along with other ingredients aimed at improving tinnitus symptoms. In this prospective study, we focused on patients suffering from subjective tinnitus that also had a notable emotional impact.
Over three months, participants reported changes in their tinnitus experience, specifically using the Tinnitus Handicap Inventory (THI) to gauge any differences. What we found was quite notable: participants experienced a significant decrease in THI scores, indicating fewer difficulties related to their tinnitus.
Notably, while the supplement showed promise in reducing tinnitus loudness and emotional distress, it’s important to mention that hearing status remained unchanged. Although magnesium was part of the supplement, we couldn't isolate its effects specifically on tinnitus, as it was combined with several other compounds.
Additionally, the study reported a few mild adverse events related to treatment, but overall, the safety profile was quite reassuring. In conclusion, while magnesium’s role in tinnitus relief is part of an effective supplement, more focused studies would be needed to understand its direct effects.
Read More
8
Magnesium effectively mitigates tinnitus
Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus.
We investigated the impact of magnesium on tinnitus, particularly in the context of its effect on long-term potentiation (LTP) in the dorsal cochlear nucleus, a critical area of the brain involved in hearing. Our research focused on a mouse model where acoustic over-exposure led to hearing loss and subsequent tinnitus.
We found that after exposure to loud sounds, there was a notable increase in the release probability at synapses in the dorsal cochlear nucleus, which saturated LTP and induced a state of metaplasticity. This chain of events could contribute to the persistent gap detection issues commonly seen in individuals with tinnitus.
However, we discovered that administering magnesium-threonate following the acoustic trauma effectively restored LTP and helped reduce the gap detection deficits linked to tinnitus. Alongside this, we also tested an NMDA receptor antagonist, which further decreased the release probability and similarly restored LTP.
These findings suggest that magnesium treatment may be a valuable early intervention to target metaplasticity and alleviates some of the debilitating effects associated with tinnitus. It supports the idea of using magnesium to potentially improve auditory function in those affected by noise-induced hearing issues.
Read More
8
Magnesium's role in tinnitus explored
Relationship between serum magnesium level and subjective tinnitus.
We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
Excellent! I experienced symptoms of magnesium deficiency, including sleep disturbances and convulsions, which alarmed me. After consulting my doctor, I’ve been taking magnesium citrate. I start with six capsules daily due to my high physical activity, gradually reducing it when feeling better. My symptoms, including tinnitus, have normalised, and the packaging is convenient.
Read More
7.5
Reduced tinnitus noise
Not the first time I’ve bought for the family. I take it twice a day with meals. My husband was initially sceptical about magnesium, but after experiencing high blood pressure and irritability, he noticed improvements after a month of taking it. His blood pressure is now normal, and symptoms like tinnitus and neck throbbing have disappeared. For me, magnesium is essential for brain nourishment and calmness. I take breaks during holidays before resuming.
Read More
7.5
Improved tinnitus symptoms
I used to suffer from tinnitus, but now the symptoms have diminished significantly and last for longer periods of time.
Read More
2
Relaxation effects
1 people found this helpful
I was told I looked more relaxed after I started taking them. I got them for tinnitus, but sadly I have not seen any improvements in that area. I believe they are good for feeling relaxed and sleep, and they also help regulate your system. I will buy again.
Read More
Frequently Asked Questions
Tinnitus is a condition characterized by the perception of sound when no external sound is present, often described as ringing, buzzing, hissing, or clicking in the ears. It can be a temporary or chronic condition, and while it's not considered a disease itself, it can be a symptom of an underlying issue, such as an ear injury, hearing loss, or exposure to loud noises. Tinnitus can significantly impact the quality of life, affecting concentration, sleep, and overall mental health.
Individuals experiencing tinnitus may find it helpful to consult a healthcare professional to identify potential causes and explore available management strategies. Treatments can range from sound therapy and hearing aids to cognitive-behavioral therapy and lifestyle changes. While there is currently no universal cure for tinnitus, understanding its nature and working with a specialist can lead to improved coping mechanisms and symptom reduction.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium has been explored as a potential supplement for managing tinnitus, although the evidence remains inconclusive. Some studies suggest that magnesium may play a role in protecting auditory function and reducing the intensity of tinnitus symptoms due to its ability to support nerve health and blood circulation. The mineral may also help in alleviating anxiety and stress, which can exacerbate the perception of tinnitus in some individuals. However, it's essential to note that while magnesium supplementation is generally considered safe for those who do not have underlying health issues, its effectiveness specifically for tinnitus relief varies from person to person.
Before starting any new supplement regimen, including magnesium, it’s vital to consult with a healthcare professional. They can provide personalized advice and ensure that any approach to managing tinnitus is safe and suitable. Additionally, a comprehensive treatment plan incorporating sound therapy, cognitive behavioral therapy, or other management strategies may be more effective than relying solely on magnesium supplementation for tinnitus relief.
Based on user reviews, it appears that the time it takes to see improvements in tinnitus symptoms can vary. Some users reported noticing noticeable changes after about a month of consistent use. For instance, one reviewer mentioned that their husband experienced improvements in not only tinnitus but also high blood pressure and irritability after a month of taking magnesium Read Review. Another user noted a significant reduction in their tinnitus symptoms, indicating that over time they have diminished significantly Read Review.
Additionally, those who have been diligent in taking the supplement regularly seem to experience longer periods of relief from their symptoms. For example, a user reported that their tinnitus symptoms normalized after they gradually adjusted their dosage based on their activity levels Read Review. Overall, while individual experiences may vary, a general timeframe of around a month seems to be a common benchmark for users assessing the effectiveness of magnesium supplementation for tinnitus.
Recent studies indicate that magnesium may hold promise as a supportive treatment for tinnitus, although more research is needed to fully validate its effectiveness. In a double-blind randomized placebo-controlled trial, the AUDISTIM supplement, which contains magnesium, significantly reduced tinnitus handicap among participants over three months [1]. Another study observed that patients taking Tinnitan Duo®, which also contains magnesium, reported a notable decrease in tinnitus severity and emotional distress, although the exact contribution of magnesium itself remains unclear, as it was combined with other active compounds [2].
Moreover, research demonstrates a fascinating link between low magnesium levels and severe tinnitus symptoms [4]. Participants deficient in magnesium recorded significantly lower serum levels compared to healthy controls, suggesting that maintaining adequate magnesium levels may impact tinnitus pathophysiology. Additionally, animal studies have indicated that magnesium can restore certain auditory functions affected by noise exposure [3]. While these findings are promising, they underscore the need for further focused studies to confirm magnesium's direct effects and mechanisms in alleviating tinnitus symptoms, suggesting that while magnesium may be a valuable tool in managing tinnitus, its isolated efficacy requires more rigorous exploration.
Users have reported a variety of improvements in symptoms related to magnesium supplementation, particularly concerning tinnitus. One user shared that after taking magnesium citrate diligently, their tinnitus symptoms normalized, alongside other magnesium deficiency issues like sleep disturbances Read Review. Another reviewer highlighted how their husband's persistent high blood pressure and irritability ceased after a month of use, with accompanying tinnitus and neck throbbing symptoms disappearing altogether Read Review.
Additionally, some individuals expressed a marked reduction in the duration and frequency of their tinnitus symptoms, noting that they experienced longer periods of relief over time Read Review. While these accounts reflect positive experiences, it is crucial to recognize that individual results can vary widely based on personal health factors and adherence to supplementation. As always, it is advisable to consult with a healthcare professional before beginning any new supplement regimen.
Users have shared diverse experiences when combining magnesium supplements with other treatments for tinnitus. Many reviewers emphasized the positive effects of magnesium supplementation on their symptoms, with one user noting that after diligently taking magnesium citrate, not only did their tinnitus normalize, but they also found relief from other magnesium deficiency-related issues like sleep disturbances Read Review. Another user observed that their husband's symptoms, including tinnitus and neck throbbing, had completely disappeared after a month of using magnesium, indicating a significant improvement when combined with other lifestyle changes Read Review.
Moreover, some users reported a marked reduction in both the frequency and duration of their tinnitus symptoms, suggesting that magnesium may contribute to longer-lasting relief over time Read Review. These accounts indicate that for some, combining magnesium supplementation with a holistic view of health—including dietary considerations and medical consultations—has led to noticeable improvements in managing tinnitus. However, individual results may vary, and it's always advisable to consult with healthcare professionals before starting any new supplement regimen.
While research on magnesium’s efficacy for tinnitus treatment is still emerging, recent studies have explored various doses and formulations incorporating magnesium. For instance, one study indicated a daily supplementation of 532 mg of magnesium for three months showed promise in alleviating tinnitus symptoms among patients experiencing moderate to severe distress [5]. However, another study using a proprietary supplement mixed with magnesium, numbers were not isolated but hinted at noticeable reductions in tinnitus burden [2]. It’s clear that magnesium may play a supportive role, yet the ideal dosage remains a subject for further investigation.
Overall, the interplay of magnesium within supplements like AUDISTIM suggests that while individual effects are difficult to ascertain, adequate magnesium intake might be beneficial [1]. Given that low magnesium levels were observed in individuals with tinnitus compared to healthy controls [4], maintaining sufficient magnesium through diet or supplementation could be a worthwhile consideration in managing tinnitus. Always consult with a healthcare professional before starting any new supplement regimen.
7.5
Reduced tinnitus noise
Not the first time I’ve bought for the family. I take it twice a day with meals. My husband was initially sceptical about magnesium, but after experiencing high blood pressure and irritability, he noticed improvements after a month of taking it. His blood pressure is now normal, and symptoms like tinnitus and neck throbbing have disappeared. For me, magnesium is essential for brain nourishment and calmness. I take breaks during holidays before resuming.
7.5
Improved tinnitus symptoms
I used to suffer from tinnitus, but now the symptoms have diminished significantly and last for longer periods of time.
9
Prevented tinnitus convulsions
Excellent! I experienced symptoms of magnesium deficiency, including sleep disturbances and convulsions, which alarmed me. After consulting my doctor, I’ve been taking magnesium citrate. I start with six capsules daily due to my high physical activity, gradually reducing it when feeling better. My symptoms, including tinnitus, have normalised, and the packaging is convenient.
8
Magnesium may alleviate tinnitus symptoms
AUDISTIM Day/Night Alleviates Tinnitus-Related Handicap in Patients with Chronic Tinnitus: A Double-Blind Randomized Placebo-Controlled Trial.
We explored the effectiveness of a daily supplement called AUDISTIM Day/Night, which includes magnesium along with various vitamins and phytochemicals, in reducing tinnitus-related challenges. Conducted as a double-blind randomized placebo-controlled trial, our research involved 114 adults with mild to severe tinnitus, looking at how this supplement might alleviate their symptoms over three months.
Our findings showed that those taking the AUDISTIM supplement experienced a more significant reduction in tinnitus handicap compared to those on a placebo. In fact, participants with continuous tinnitus reported even greater improvements. While both groups noticed some enhancements in sleep quality, it was only the group taking AUDISTIM that showed reduced psychological stress.
This study suggests that the combination of active compounds, including magnesium, could be beneficial in managing tinnitus symptoms. It aligns well with previous observations in real-life settings and offers a promising new avenue for those suffering from this challenging condition.
8
Tinnitan Duo® aids tinnitus relief
Effectiveness of Tinnitan Duo® in Subjective Tinnitus with Emotional Affectation: A Prospective, Interventional Study.
We looked into the effectiveness of a specific food supplement, Tinnitan Duo®, which contains magnesium along with other ingredients aimed at improving tinnitus symptoms. In this prospective study, we focused on patients suffering from subjective tinnitus that also had a notable emotional impact.
Over three months, participants reported changes in their tinnitus experience, specifically using the Tinnitus Handicap Inventory (THI) to gauge any differences. What we found was quite notable: participants experienced a significant decrease in THI scores, indicating fewer difficulties related to their tinnitus.
Notably, while the supplement showed promise in reducing tinnitus loudness and emotional distress, it’s important to mention that hearing status remained unchanged. Although magnesium was part of the supplement, we couldn't isolate its effects specifically on tinnitus, as it was combined with several other compounds.
Additionally, the study reported a few mild adverse events related to treatment, but overall, the safety profile was quite reassuring. In conclusion, while magnesium’s role in tinnitus relief is part of an effective supplement, more focused studies would be needed to understand its direct effects.
8
Magnesium's role in tinnitus explored
Relationship between serum magnesium level and subjective tinnitus.
We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
8
Magnesium effectively mitigates tinnitus
Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus.
We investigated the impact of magnesium on tinnitus, particularly in the context of its effect on long-term potentiation (LTP) in the dorsal cochlear nucleus, a critical area of the brain involved in hearing. Our research focused on a mouse model where acoustic over-exposure led to hearing loss and subsequent tinnitus.
We found that after exposure to loud sounds, there was a notable increase in the release probability at synapses in the dorsal cochlear nucleus, which saturated LTP and induced a state of metaplasticity. This chain of events could contribute to the persistent gap detection issues commonly seen in individuals with tinnitus.
However, we discovered that administering magnesium-threonate following the acoustic trauma effectively restored LTP and helped reduce the gap detection deficits linked to tinnitus. Alongside this, we also tested an NMDA receptor antagonist, which further decreased the release probability and similarly restored LTP.
These findings suggest that magnesium treatment may be a valuable early intervention to target metaplasticity and alleviates some of the debilitating effects associated with tinnitus. It supports the idea of using magnesium to potentially improve auditory function in those affected by noise-induced hearing issues.
7
Magnesium may ease tinnitus symptoms
Phase 2 study examining magnesium-dependent tinnitus.
We set out to understand whether magnesium supplementation could help alleviate tinnitus, a persistent ringing or noise in the ears that affects many individuals. In our study, we observed 26 patients who were experiencing moderate to severe tinnitus symptoms. Over three months, participants took a daily dose of 532 mg of magnesium and reported their tinnitus severity using a simple scale.
Patients rated their tinnitus distress each day, while also completing a standardized questionnaire at the beginning and end of the study. This approach allowed us to gather direct feedback from participants about their experiences with magnesium. After analyzing the results, it became clear that magnesium might indeed have a positive effect on reducing the perceived handicap associated with tinnitus.
Although we did not use a placebo group for this exploratory phase, the findings suggest there could be real potential for magnesium as a supportive treatment for those struggling with tinnitus. It’s encouraging to think that something as common as magnesium, often lacking in many diets, could make a difference for individuals dealing with this challenging condition.
References
Portmann D, Esteve-Fraysse MJ, Frachet B, Herpin F, Rigaudier F, et al. AUDISTIM Day/Night Alleviates Tinnitus-Related Handicap in Patients with Chronic Tinnitus: A Double-Blind Randomized Placebo-Controlled Trial. Audiol Res. 2024;14:359. doi:10.3390/audiolres14020031
Knäpper J, Girauta MV, Coromina J. Effectiveness of Tinnitan Duo® in Subjective Tinnitus with Emotional Affectation: A Prospective, Interventional Study. J Diet Suppl. 2023;20:1. doi:10.1080/19390211.2021.1944947
Tagoe T, Deeping D, Hamann M. Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus. Exp Neurol. 2017;292:1. doi:10.1016/j.expneurol.2017.02.011
Uluyol S, Kılıçaslan S, Yağız Ö. Relationship between serum magnesium level and subjective tinnitus. Kulak Burun Bogaz Ihtis Derg. 2016;26:225. doi:10.5606/kbbihtisas.2016.87094
Cevette MJ, Barrs DM, Patel A, Conroy KP, Sydlowski S, et al. Phase 2 study examining magnesium-dependent tinnitus. Int Tinnitus J. 2011;16:168.
Ehrenberger K, Felix D. Receptor pharmacological models for inner ear therapies with emphasis on glutamate receptors: a survey. Acta Otolaryngol. 1995;115:236.